Effects of movement behaviors on preschoolers’ cognition: a systematic review of randomized controlled trials by Catalina Pacheco, Victoria Culkin, Amelia Putkaradze, Nan Zeng

“…Future research should focus on integrated interventions that address PA, SB, and sleep to achieve a more comprehensive understanding of their collective impact on cognitive development in early childhood. Trial registration This study was registered with PROSPERO under the registration number CRD42023479156.…”
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Evaluation of pre-treatment effect of Moringa peregrina) Forssk( Fiori seed to improve germination and increase seedling establishment rate for its preservation and development in... by marzeyh Rezai, Naeges Palashi, Farzin Abdolahi, Hamid Moslemi

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DEveloping Tests for Endometrial Cancer deTection (DETECT): protocol for a diagnostic accuracy study of urine and vaginal samples for the detection of endometrial cancer by cytolog... by Suzanne Carter, Eleanor R Jones

“…Results will be disseminated through publication in peer-reviewed scientific journals, presentation at conferences and via charity websites.Trial registration number ISRCTN58863784.…”
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Protocol for a case–control diagnostic accuracy study to develop diagnostic criteria for psoriasis in children (DIPSOC study): a multicentre study recruiting in UK paediatric derma... by Kim Suzanne Thomas, Esther Burden-Teh, Ruth Murphy, Sonia Gran, Tamar Nijsten, Carolyn Hughes

“…The aim of this study is to develop clinical examination and history-based diagnostic criteria for psoriasis in children to help differentiate psoriasis from other scaly inflammatory rashes. …”
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Development and validation of a risk assessment model for predicting the failure of early medical abortions: A clinical prediction model study based on a systematic review and meta... by An-Hao Liu, Bin Xu, Xiu-Wen Li, Yue-Wen Yu, Hui-Xin Guan, Xiao-Lu Sun, Yan-Zhen Lin, Li-Li Zhang, Xian-Di Zhuo, Jia Li, Wen-Qun Chen, Wen-Feng Hu, Ming-Zhu Ye, Xiu-Min Huang, Xun Chen

“…<h4>Objective</h4>As the first model in predicting the failure of early medical abortion (EMA) was inefficient, this study aims to develop and validate a risk assessment model for predicting the failure of EMAs more accurately in a clinical setting.…”
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Factors associated with Anganwadi Workers' service delivery of Integrated Child Development Services (ICDS) in rural India: A cross-sectional analysis of household and community he... by Lakshmi Gopalakrishnan, Sumeet Patil, Lia Fernald, Dilys Walker, Nadia Diamond-Smith

“…<h4>Objectives</h4>India's 1.4 million Anganwadi Workers (AWW), a type of community health worker (CHW), serve 158 million beneficiaries under the Integrated Child Development Services (ICDS) program. They play a crucial role in facilitating the delivery of nutrition services at the village level in India. …”
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Treatment of e-cigarette use among hospitalised adolescents and young adults: a protocol for intervention development and evaluation of preliminary efficacy and implementation outc... by Delwyn Catley, Kimber P Richter, Karen Wilson, Shelbie Wooten, Melissa K Miller, Abbey Masonbrink

“…Study results will be disseminated to our public committee, youth research advisory board, to relevant stakeholders and through publication.Trial registration number NCT05936099; registered on 30 June 2023. …”
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Four-year follow-up to a home-visiting intervention to promote early childhood development and prevent family violence in rural Rwanda: the Sugira Muryango cluster randomised trial by Theresa S Betancourt, Matias Placencio-Castro, Shauna M Murray, Vincent Sezibera, Sarah G K Jensen, Jess Littman, Stephanie M Bazubagira, Dieudonne Uwizeye

“…Programme updates may be required to support children’s continued cognitive growth.Trial registration number NCT02510313.…”
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Development of a Diagnostic Prediction Model for Post‐Stroke Cognitive Impairment in Acute Large Vessel Occlusion Stroke Using Multimodal MRI and PET/CT: A Study Protocol by Junhao Li, Yuding Luo, Pingchuan Liu, Jiali Zhang, Chuanxi Duan, Hai Xiong, Maoxia Li, Binyang Zhang, Lu Li, Lulu Gong, Yupeng Niu, Bo Zheng, Jian Wang

“…Baseline imaging data will be processed using 3D Slicer for MRI and PET/CT standardization, registration, and feature extraction. Machine learning models will be developed using these imaging features combined with demographic and clinical data and evaluated via metrics such as the area under the receiver operating characteristic curve, precision, and recall. …”
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Co-developing an intervention to facilitate safe and early transition to neonatal home care for very preterm infants: a mixed-method study evaluating the impact of patient and publ... by Sofia Arwehed, Ylva Thernström Blomqvist, Elin Carlsson Filipowicz, Anna Axelin

“…Field notes, post-it notes, mind maps, and audio recordings supported data validation. Results The co-development process resulted in an intervention tool designed to visualise the neonatal care journey, discharge criteria, infant development, and parental preparation, including milestones to track progress and strengthen parental roles. …”
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DAWN: Designing Distributed Agents in a Worldwide Network by Zahra Aminiranjbar, Jianan Tang, Qiudan Wang, Shubha Pant, Mahesh Viswanathan

“…These advancements have led to the development of specialized LLM-based agents designed for diverse tasks such as coding and web browsing. …”
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Development of a large Danish single-centre retro- and prospective transgender cohort using a web-based platform: a study protocol of a transgender cohort study by Ulrik Schiøler Kesmodel, Allan Stensballe, Emma Elisabeth Skovby Petersen, Frederika Kiy, Michael Winterdahl, Jakob Dal, Maria Lucia Pop, Gry Kjaersdam Telléus, Astrid Ditte Højgaard

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Effects of improved complementary feeding and improved water, sanitation and hygiene on early child development among HIV-exposed children: substudy of a cluster randomised trial i... by Lawrence H Moulton, Melissa Gladstone, Jaya Chandna, Robert Ntozini, Kuda Mutasa, Jean H Humphrey, Andrew J Prendergast, Bernard Chasekwa, Ceri Evans, Gwendoline Kandawasvika, Batsirai Mutasa, Florence D Majo, Naume V Tavengwa, Mduduzi NN Mbuya

“…There was no evidence that that any intervention impacted object permanence or self-control.Conclusions Combining IYCF and WASH interventions significantly improved motor, language and cognitive development in HIV-exposed children.Trial registration number NCT01824940.…”
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Development of a multicentre cohort study to understand the role of MRI and ultrasound in the diagnosis of acute haematogenous bone and joint infection in children (the PIC Bone st... by Marie-Caroline Nogaro, Stuart Hartshorn, Mariea Brady, Amaka Offiah, Saul Faust, Gregory Firth, Jie Ma, Paula Dhiman, Joanna O'Mahoney, Loretta Davies, Catherine Spowart, Amy Moscrop, Bridget Young, Catrin Tudur-Smith, Gary Collins, Daniel C. Perry, Tim Theologis

“…Discussion: Ethical approval for this study (registration: ISRCTN15471635) was granted (REC reference 23/WM/0027). …”
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Development of a Smartphone‐Enabled Hypertension and Diabetes Mellitus Management Package to Facilitate Evidence‐Based Care Delivery in Primary Healthcare Facilities in India: The... by Vamadevan S. Ajay, Devraj Jindal, Ambuj Roy, Vidya Venugopal, Rakshit Sharma, Abha Pawar, Sanjay Kinra, Nikhil Tandon, Dorairaj Prabhakaran

“…Methods and Results The development of the intervention and mobile phone–based clinical decision support system was carried out using mixed methods in five Community Health Centers. …”
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Developing and validating utility parameters to establish patient-reported outcome-based perioperative symptom management in patients with lung cancer: a multicentre, prospective,... by Rui Zhang, Wei Dai, Qiang Li, Shaohua Xie, Qiuling Shi, Yuanqiang Zhang, Wenhong Feng, Xiaoqing Liao, Yunfei Mu, Xing Wei, Chuanmei Wu, Heling Zhou, Xuemei Cheng, Yanhua Jiang, Jintao He, Xiaojun Yang

“…The results of this study will be presented at medical conferences and published in peer-reviewed journals.Trials registration number NCT03341377.…”
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Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings... by Hassan Haghparast-Bidgoli, Michelle Heys, Caroline Crehan, Erin Kesler, Monica Lakhanpaul, Emma Wilson, Fabiana Lorencatto, Felicity Fitzgerald, Mario Cortina Borja, Msandeni Chiume, Hannah Gannon, Simbarashe Chimhuya, Gwendoline Chimhini, Tim Hull-Bailey, Tarisai Chiyaka, Yali Sassoon, Deliwe Nkhoma, Nushrat Khan, Alexander G. Stevenson, Kristina Curtis

“…Since 2014, we have worked in Bangladesh, Malawi, Zimbabwe and the UK to develop and pilot Neotree: an android app with accompanying data visualisation, linkage and export. …”
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Developing a Novel Mobile App to Support HIV Testing and Pre-Exposure Prophylaxis Uptake Among Men Who Have Sex With Men: Formative and Technical Pilot Study by Albert Y Liu, Thiago S Torres, Cat-Dancing Alleyne, Janie Vinson, Kelly Bojan, Pedro Alonso Serrano, Temitope Oyedele, Amayvis Garcia, Elizabeth Enriquez-Bruce, Patricia Emmanuel, Jeb Jones, Kathryn E Muessig, Susan P Buchbinder, Patrick Sullivan, Lisa B Hightow-Weidman, Hyman Scott

“…ObjectiveThis study aims to describe the development and assess the feasibility and acceptability of LYNX, a mobile app to increase HIV testing and PrEP uptake among YSMM. …”
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Association between levothyroxine treatment for maternal subclinical hypothyroidism with negative TPOAb and early child neurodevelopment: A prospective real‐world clinical trial by Zhekun Zhao, Qiongjie Zhou, Huanqiang Zhao, Yu Xiong, Xiaotian Li

“…Child neurodevelopment was assessed by the Gesell development diagnosis scale (GDDS) at one, three, six, 12, and 24 months of age. …”
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Music therapy embedded in the life of dementia inpatient care to help prevent and manage distress: a feasibility study to inform a future trial by Naomi Thompson, Naomi Thompson, Helen Odell-Miller, Helen Odell-Miller, Chris Pointon, Chris Pointon, Benjamin R. Underwood, Benjamin R. Underwood, Benjamin R. Underwood, Emma Wolverson, Emma Wolverson, Emma Wolverson, Rachel Hunt, Rachel Hunt, Joanne Inglis, Joanne Inglis, Abdulwarrith Olawale, Lucy Pickering, Lucy Pickering, Alison Wilkinson, Alison Wilkinson, Christine Wise, Christine Wise, Cansu Buyukulas, Robert Dudas, Robert Dudas, Jufen Zhang, Ming-Hung Hsu, Ming-Hung Hsu

“…This protocolised intervention should be tested for clinical effectiveness in a controlled trial.RegistrationISRCTN86317609…”
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