Quality of aerobic training description and its relation to intervention efficacy in chronic obstructive pulmonary disease trials: study protocol for a systematic review, meta-anal... by André Nyberg, Peter Klijn, Anouk A F Stoffels, Jana de Brandt, Hieronymus W H van Hees, Johan Jakobsson

“…Study quality will be assessed using the Tool for the assESsment of sTudy quality and bias in Exercise, specifically developed for exercise training studies. The certainty of the evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation approach. …”
Get full text

Application of medical products: mandatory requirements, supervision of their compliance by O. A. Makhova

“…Specific features of medical products (MPs), their active development and implementation in healthcare require post-market control and safe use.Objective: to study the existing state regulation in the field of medical products, methods of state control, self-control in medical organisations for their use.Material and methods. …”
Get full text

Effects of acupuncture on pregnancy outcomes in infertile women with polycystic ovarian syndrome: a protocol for systematic review and meta-analysis by Xiaoyan Wang, Huanfang Xu, Yigong Fang, Jiashan Li, Tian Hang

“…Evidence strength will be graded using the Grading of Recommendations Assessment, Development and Evaluation system. This protocol is developed following the guidelines of PRISMA-P 2015.Ethics and dissemination Ethics approval is not required for this review. …”
Get full text

Retrospective cohort study evaluating clinical, biochemical and pharmacological prognostic factors for prostate cancer progression using primary care data by Margaret T May, Samuel William David Merriel, Richard M Martin, Suzanne Marie Ingle

“…Objectives To confirm the association of previously reported prognostic factors with future progression of localised prostate cancer using primary care data and identify new potential prognostic factors for further assessment in prognostic model development and validation.Design Retrospective cohort study, employing Cox proportional hazards regression controlling for age, prostate specific antigen (PSA), and Gleason score, was stratified by diagnostic stage.Setting Primary care in England.Participants Males with localised prostate cancer diagnosedbetween 01/01/1987 and 31/12/2016 within the Clinical Practice ResearchDatalink database, with linked data from the National Cancer Registration andAnalysis Service and Office for National Statistics.Primary and secondary outcomes Primary outcome measure was prostate cancer mortality. …”
Get full text

Financial Fraud Detection on Social Networks Based on a Data Mining Approach by Victoria Bozhenko, Serhii Mynenko, Artem Shtefan

“…The urgency of solving this scientific problem is due to the fact that the mass involvement of Internet users in social interactions in the virtual environment has contributed to the development of various criminal schemes, as well as personal data that is initially entered during registration and information that is published in social networks can be used by a fraudster to carry out illegal financial transactions. …”
Get full text

The efficacy of promoting sustained shared thinking through the use of activity books on parental empowerment; A quasi-experimental study. by Kamolvisa Techapoonpon, Wisarat Pruttithavorn, May Sripatanaskul, Niyata Limpiti, Kahwei Yoong

“…The format of this intervention is primarily self-directed activity, providing a solution that can be replicated and further developed in the future. Clinical trial registration: Thai Clinical Trials Registry (TCTR20221203002).…”
Get full text

Key determinants in implementation processes: a systematic review using the Consolidated Framework for Implementation Research (CFIR) by Marin Schmitt, Maren Hawkins, Paul Florsheim

“…Damschroder & Lowery (2013) developed a rating system to assess which Consolidated Framework for Implementation Research (CFIR) constructs have the strongest impact on implementation. …”
Get full text

Determinants of physical activity level in pediatric oncological patients treated with cardiotoxic therapy – a study protocol by Julia Haponiuk-Skwarlińska, Jakub S. Gąsior, Katarzyna Albrecht, Paweł Łaguna, Bożena Werner

“…Trial registration NCT06256068.…”
Get full text

Estimation of productivity indicators of new winter wheat varieties in the steppe Crimea by L. A. Radchenko, T. L. Averchenko, D. M. Marchenko

“…The purpose of the current study was to estimate the main elements of productivity and yield of new winter common wheat varieties developed by the FSBSI “ARC “Donskoy” in the contrasting weather conditions of the steppe Crimea. …”
Get full text

Understanding barriers to young people’s utilisation of sexual and reproductive health services in Asia-Pacific countries: a qualitative systematic review and thematic synthesis by Daniel Mackay, Benjamin Gregory, Evi Germeni, Watcharakorn Riabroi

“…Thematic synthesis identified six descriptive themes that captured factors influencing SRH service utilisation: (1) navigating puberty; (2) knowledge and beliefs about SRH; (3) embarrassment and confidentiality concerns; (4) low decision-making autonomy; (5) traditional practices and religious beliefs; and (6) social and gender norms. Based on these, we developed an overarching analytical theme, ‘trapped in a legacy of shame’, which highlights the role of shame as a key emotion associated with young people’s utilisation of SRH services.Conclusion Our findings point towards the necessity of integrating shame-sensitive approaches and a social norms perspective in interventions aiming to improve young people’s SRH outcomes in Asia-Pacific countries.PROSPERO registration number CRD42023389653.…”
Get full text

Association between RANTES/CCL5 levels with Plasmodium infections and malaria severity: a systematic review by Pattamaporn Kwankaew, Aongart Mahittikorn, Wanida Mala, Kwuntida Uthaisar Kotepui, Nsoh Godwin Anabire, Polrat Wilairatana, Manas Kotepui

“…Abstract Background Malaria continues to be a significant global health concern, and developing effective therapeutic strategies requires an understanding of the immune response to the disease. …”
Get full text

Design, implementation, and evaluation of a psychosocial intervention to improve mental health in pregnant adolescents: a mixed-methods protocol by Setareh Yousefi, Simin Montazeri, Nahid Javadifar, Saeed Ghanbari

“…Second, insights from the qualitative phase will inform the development of a targeted intervention, guided by expert consensus using the Nominal Group Technique. …”
Get full text

Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge. by Damian A Oyong, Fergal J Duffy, Maxwell L Neal, Ying Du, Jason Carnes, Katharine V Schwedhelm, Nina Hertoghs, Seong-Hwan Jun, Helen Miller, John D Aitchison, Stephen C De Rosa, Evan W Newell, M Juliana McElrath, Suzanne M McDermott, Kenneth D Stuart

“…Understanding immune mechanisms that mediate malaria protection is critical for improving vaccine development. Vaccination with radiation-attenuated Plasmodium falciparum sporozoites (PfRAS) induces high level of sterilizing immunity against malaria and serves as a valuable tool for the study of protective mechanisms. …”
Get full text

How effective and cost-effective are behaviour change interventions in improving the prescription and use of antibiotics in low-income and middle-income countries? A protocol for a... by Mishal Khan, Virginia Wiseman, Neha Batura, Carla Cuevas

“…A meta-analysis or narrative synthesis will be conducted as appropriate, along with an appraisal of quality of studies using the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) checklist.Ethics and dissemination No individual patient data are used, so ethical approval is not required. …”
Get full text

Barriers and facilitators to the use of clinical practice guidelines in osteoarthritis care: a qualitative study among German physiotherapists by Carolin Bahns, Lisa Happe, Christian Kopkow

“…The results of this study can inform the development of theory-based interventions aimed at changing physiotherapists’ behaviour to support them in providing optimal OA care.Trial registration German Clinical Trials Register (DRKS00030800). …”
Get full text

Common bacterial infections and risk of incident cognitive decline or dementia: a systematic review protocol by Liam Smeeth, Carol Brayne, Krishnan Bhaskaran, Rutendo Muzambi, Charlotte Warren-Gash

“…Introduction The global burden of dementia is rising, emphasising the urgent need to develop effective approaches to risk reduction. Recent evidence suggests that common bacterial infections may increase the risk of dementia, however the magnitude and timing of the association as well as the patient groups affected remains unclear. …”
Get full text

Relationship between dietary antioxidants and hypertension with the role of genetic factors: a scoping review protocol by Tao Liu, Jianwei Zeng, Miao Huang, Ru Fu, Xiaogang Li, Weihong Jiang

“…Oxidative stress is considered a critical factor in the development of hypertension. Diet plays a crucial role in hypertension management due to its routine and non-pharmacological nature, and dietary natural antioxidants are believed to play a role in reducing oxidative stress. …”
Get full text

Mapping the impact, sustainability and pedagogical frameworks of international virtual knowledge exchanges in global health: Protocol for a scoping review [version 1; peer review:... by Oisin Brady Bates, Divya Iyer, Alexandru Nicholas Grecu, Walter Cullen, Diarmuid Stokes, Joseph Gallagher

“…Understanding the pedagogical underpinnings, challenges, and best practices of virtual exchanges is vital for developing scalable and sustainable integration into healthcare education. …”
Get full text

Perceptions of human papillomavirus vaccination among adolescent boys and their parents in high-income countries: a scoping review protocol by Eunyoung Park, Hyun-Ju Seo, Yumi Choi, Jisu Seo, Hye-Jeong Yang

“…However, among adolescent boys, initial exposure to HPV is associated with a higher risk of developing oropharyngeal and oral cancers compared with girls. …”
Get full text

Analysis of the media coverage characteristics on radiation safety issues of the Saint-Petersburg and the Leningrad region population by A. M. Biblin

“…The study was performed by this system as a development and improvement of the Center’s works applicable to the registration, storage, and analysis of qualitative and quantitative information contained in the publications. …”
Get full text