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Barriers and facilitators to nurses’ adoption of artificial intelligence-driven solutions in clinical practice: a protocol for a systematic review of qualitative studies
Published 2025-08-01“…Introduction Artificial intelligence (AI) technologies are increasingly being developed and deployed to support clinical decision-making, care delivery and patient monitoring in healthcare. …”
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Interventions and practice models for improving health and psychosocial outcomes of children and young people in out-of-home care: protocol for a systematic review
Published 2019-09-01“…Trauma in early childhood can impact on children’s health and psychosocial development, whereas early interventions can improve children’s development and placement stability. …”
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Understanding why resident doctors leave the NHS and what can be done to retain them: protocol for a realist synthesis
Published 2025-08-01“…This realist synthesis will examine how, why and in what contexts resident doctors leave the National Health Service, and what interventions might support their retention.Methods and analysis This realist synthesis will follow Realist And Meta-narrative Evidence Synthesis: Evolving Standards guidance and will be conducted in five iterative steps: (1) identifying existing theories to develop an initial programme theory; (2) undertaking formal and purposive searches to identify relevant UK-based literature; (3) selecting documents based on relevance and rigour; (4) extracting and coding data to support the development of explanatory insights; and (5) synthesising findings using a realist logic of analysis to develop and refine context-mechanism-outcome configurations. …”
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Population-pharmacokinetic/pharmacodynamic model of atractylodes lancea (Thunb.) DC. administration in patients with advanced-stage intrahepatic cholangiocarcinoma: a dosage predic...
Published 2024-11-01“…Conclusions The applied pop-PK model with MC simulation, along with the appropriate cut-off pharmacokinetic parameters, can be used as a potential tool for supporting dosage prediction and selection for clinical studies, and thus reducing the rate of drug development failures. Trial registration www.thaiclinicaltrials.org , WHO ICTRP search, TCTR20210129007 , Registed 29 January 2021.…”
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Association of TLR2 Arg753Gln gene polymorphism with its expression level in nonagenarians with frailty
Published 2024-07-01“…Frailty was detected in 41 subjects using a short physical performance battery, with registration in the test ≤ 7 points. It was shown that carriage of the Gln allele is statistically significantly associated with an increased risk of developing frailty; patients with the Arg/Gln genotype have a 12.8-fold higher chance of developing this geriatric syndrome. …”
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The Impact of Long-Chain Omega-3 Polyunsaturated Fatty Acid Supplementation in Pregnant Women Toward the Intelligence Status of Early Childhood: Protocol for a Systematic Review an...
Published 2025-04-01“… BackgroundLong-chain omega-3 polyunsaturated fatty acids (LCPUFAs) are essential fatty acids that protect cellular structures and provide energy, particularly for fetal growth and development. The maternal supplementations of omega-3 LCPUFA may affect the rate of intelligence in early childhood development. …”
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Cognitive–behavioral therapy-based intervention to treat symptoms of anxiety in pregnancy in a prenatal clinic using non-specialist providers in Pakistan: design of a randomised tr...
Published 2020-04-01“…Identification of an evidence-based intervention for anxiety starting in early pregnancy to mid pregnancy may be transferable for use and scale-up in other low-income and middle-income countries.Trial registration number NCT03880032.…”
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Establishment of Russian Oncology before the Great Patriotic War
Published 2020-05-01“…Soviet scientists-enthusiasts made a significant contribution to the development of oncology in the USSR. The organisation of medical professional societies facilitated the determination of main directions in the development of oncology as a discipline in the country. …”
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Association of myeloid cell reactivity patterns with safe food predictions in FPIES patients
Published 2025-05-01“…As there are no extant methods to identify safe foods for FPIES patients, food ingestion trials are performed at home and often lead to reactions and development of food aversions, which may lead to failure-to-thrive and gastric feeding tube requirements. …”
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Prevalence of metabolic dysfunction‐associated steatotic liver disease in people living with HIV and on antiretroviral treatment: A systematic review and meta‐analysis protocol
Published 2024-11-01“…Literature suggests that human immunodeficiency virus‐infected (HIV‐infected) individuals may have an increased risk of developing MASLD due to a complex interplay of factors including antiretroviral therapy. …”
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Landscaping the evidence of intimate partner violence and postpartum depression: a systematic review
Published 2022-05-01“…The majority of the studies were judged as ‘good quality’ (n=20/33).Conclusion We found evidence of an association between exposure to IPV and the development of signs of postpartum depression. Meta-analysis or individual patient data meta-analysis is required to quantify the magnitude of the association between IPV and postpartum depression.PROSPERO registration number CRD42020209435.…”
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Have interventions aimed at assisting general practitioners in facilitating earlier diagnosis of type 1 diabetes in children been successful? A systematic review protocol
Published 2023-12-01“…DKA is a life-threatening emergency where dehydration and cerebral oedema can quickly develop and lead to death. Despite treatment, DKA also has harmful impacts on cognition and brain development. …”
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Viral gastroenteritis in children: modern concepts of epidemiology and prevention
Published 2015-11-01“…After the introduction of mass vaccination against rotaviruses in developed countries increases the share of astroviral and adenoviral infection in the structure of the AII. …”
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Choice of primary healthcare providers among population in urban areas of low- and middle-income countries—a protocol for systematic review of literature
Published 2024-11-01“…An Excel-based data extraction table will be developed, piloted, and refined during the review process. …”
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