New possibilities of pharmacotherapy for systemic lupus erythematosus: A place of belimumab by E. L. Nasonov

“…Various defects in the T cells regulating a B cell immune response have been detected. The development of genetic, epigenomic, transcriptomic, and proteomic technologies could identify a group of pathogenetically relevant cytokines, including BLyS (the B-lymphocyte stimulator is the most important component of cytokine-mediated regulation of B cell function, proliferation, and differentiation), interleukin (IL) 6, 17, 18, type 1 interferon, and tumor necrosis factor-α, which are involved in the development of visceral inflammation and damage.Large-scale clinical trials of different medications, primarily biological agents (BA), were conducted in patients with SLE. …”
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Nursing regulation in Canada: Insights from a scoping review. by Patrick Chiu, Natalie J Thiessen, Sobia Idrees, Kathleen Leslie, Janice Y Kung

“…This highlights opportunities for regulators and researchers to enhance collaboration to co-create research agendas that can maximize knowledge development and mobilization efforts.…”
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Diagnostic yield of chest and thumb ECG after cryptogenic stroke, Transient ECG Assessment in Stroke Evaluation (TEASE): an observational trial by Peter Magnusson, Adam Lyren, Gustav Mattsson

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Do insomnia and/or sleep disturbances predict the onset, relapse or worsening of depression in community and clinical samples of children and youth? Protocol for a systematic revie... by Sarah Bonato, Peter Szatmari, John D Haltigan, Cecilia Marino, Brendan Andrade, Madison Aitken

“…Introduction Disturbed sleep represents a potentially important modifiable risk factor for the development of depression in children and youth. This protocol for a systematic review proposes to investigate whether insomnia and/or sleep disturbances predict child and youth depression in community and clinical-based samples.Methods and analysis The protocol adheres to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. …”
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The relevance of using methods of molecular epidemiology of HIV to characterize territorial epidemics: Sakhalin region, Russia by I. P. Osipova, A. V. Totmenin, P. G. Bersenev, E. Yu. Ilyina, E. A. Lomakina, N. M. Gashnikova

“…Studying the peculiarities of HIV infection spread in individual regions of Russia is important for the development of effective measures aimed at ending HIV transmission in the country.…”
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Point-of-care ultrasound (POCUS) Programme 2024-25 by Ahmed Mohammad Shamsul Hoque, Reehum Masud

“…This programme supports competency development in ultrasound imaging for rapid diagnosis and clinical decision-making. …”
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Design of an international, phase IV, open-label study of simoctocog alfa in women/girls with hemophilia A undergoing surgery (NuDIMENSION) by Natascha Marquardt, Florian Langer, Katharina Holstein, María Teresa Álvarez Román, Ramiro Núñez Vázquez, Predrag Miljić, Nicolas Drillaud, Laurent Ardillon, Anna-Elina Lehtinen, Rita Carlotta Santoro, Mariasanta Napolitano, Sergio Siragusa, Gillian Gidley, Martina Jansen, Sigurd Knaub, Johannes Oldenburg

“…Trial Registration: CT EU 2022-502061-17-00; NCT05936580…”
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Microsimulation models on child and adolescent health: a scoping review protocol by Filipa Sampaio, Claire de Oliveira

“…In addition, we will use this information to guide the development of a microsimulation model on child and adolescent health for use in the Swedish context.Registration details https://osf.io/a8txn/…”
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Dietary pattern and risk of thyroid cancer: a systematic review and meta-analysis protocol by Kleyton Santos Medeiros, Jose Brandao-Neto, Yasmin Guerreiro Nagashima, Aline Alves Soares, Camila Xavier Alves, Marcia Marilia Gomes Dantas Lopes

“…While there is currently no conclusive evidence linking dietary factors to thyroid cancer, certain dietary patterns seem to have an impact on the development of the disease. There are interesting connections among diet, environment, metabolism and thyroid carcinogenesis; a deeper comprehension of the underlying mechanisms should help the identification of modifiable risk factors for thyroid cancer. …”
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Family and marriage social institution in young people’s minds and its support in modern Russia by T. E. Petrova, Z. V. Zhiratkova, A. G. Kovalchuk

“…The impact of globalization, rapid technological development, and changing social norms on traditional ideas about family and marriage has been considered. …”
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Prevalence of spontaneous movement disorders (dyskinesia, parkinsonism, akathisia and dystonia) in never-treated patients with chronic and first-episode psychosis: a systematic rev... by Arturas Kalniunas, Katie James, Sofia Pappa

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Autonomous Waste Classification Using Multi-Agent Systems and Blockchain: A Low-Cost Intelligent Approach by Sergio García González, David Cruz García, Rubén Herrero Pérez, Arturo Álvarez Sanchez, Gabriel Villarrubia González

“…This article describes the development and implementation of a prototype of a smart bin that automatically sorts waste using a multi-agent system and blockchain integration. …”
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Effects of planting date and seed priming on partitioning coefficients, grain yield and yield components of wheat(Triticum aestivum) by حمیدرضا شریفی, Gholamali Gazanchian, Sedigheh Anahid

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After-discharge activity as a basis to change intraoperative mapping protocol for functionally significant brain areas by M. G. Podgurskaya, D. S. Kanshina, A. V. Dimertsev, M. V. Alexandrov, S. S. Nikitin

“…In the first case, AD was registered while FAs mapping in a patient with a history of one epileptic seizure, upon reaching the maximum stimulation force of 2.5 mA, that was replaced by recording focal epileptiform activity with the following evolution to ictal generalized event and development of intraoperative convulsive seizure. In the second patient with a history of recurrent epileptic seizures, AD with spatiotemporal evolution of the pattern development of clinical ictal event was registered with stimulation at 2.5 mA. …”
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A quantitative study to evaluate the controls and accountability measures in place to alleviate the leadership and governance challenges impacting the realization of the National H... by Samuel Vuyo Mokoena, Panjasaram Naidoo

“…Further objective of the study was to evaluate if there were appropriate controls and accountability measures in leadership and governance to inform the development of a workable model for the implementation of the NHI in South Africa. …”
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Association of arterial stiffness and eye disease: a systematic review and meta-analysis by Robert Scragg, Angela L Beros, John D Sluyter

“…The 19 cohort studies identified (five for AMD, three for glaucoma, one for RVO and 10 for retinopathy) indicated overall that increased arterial stiffness was associated with the future development of eye disease.Conclusions Higher arterial stiffness is associated with AMD, glaucoma, RVO and retinopathyPROSPERO registration number CRD42019129563.…”
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Applications of multispectral autofluorescence imaging of malignant tumors by G. V. Papayan, N. N. Petrishchev, S. V. Kim, Hyung Ho Kim, V. B. Berezin, Uk Kang

“…The obtained results are intended to help in the development of endoscopic methods of imaging and devices for diagnosis of early tumors.…”
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Study protocol testing feasibility of the Comfort Measures Only Time out (CMOT) to reduce distress during palliative withdrawal of mechanical ventilation by Abigail G. Fischer, Margaret L. Campbell, Margaret M. Hayes, Richard M. Schwartzstein, Douglas B. White, Susan L. Mitchell, Corey R. Fehnel

“…Intervention development was guided by published literature and a structured inter-professional advisory panel. …”
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Parenting Knowledge of Urban Chinese Postpartum Women: The Role of Spousal Support and Women’s Affective Well-Being by He S, Chen Y

“…Shanshan He, Yihua Chen School of Social Development, East China Normal University, Shanghai, People’s Republic of ChinaCorrespondence: Yihua Chen, School of Social Development, No. 500 Dongchuan Road, East China Normal University, Shanghai, People’s Republic of China, Email chenyihua95@163.comPurpose: The purpose of this study was to examine parenting knowledge’s perceived level, sources, and predictors among urban Chinese postpartum women, including sociodemographic and psychosocial factors.Methods: Survey data was collected from 498 postpartum women who just gave birth within one year in Shanghai, China. …”
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Tezepelumab can Restore Normal Lung Function in Patients with Severe, Uncontrolled Asthma: Pooled Results from the PATHWAY and NAVIGATOR Studies by Ian D. Pavord, Christopher E. Brightling, Stephanie Korn, Nicole L. Martin, Sandhia S. Ponnarambil, Nestor A. Molfino, Jane R. Parnes, Christopher S. Ambrose

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