Home management by remote self‐monitoring in intermediate‐ and high‐risk pregnancies: A retrospective study of 400 consecutive women by Anne Rahbek Zizzo, Lone Hvidman, Jannie Dalby Salvig, Lone Holst, Morten Kyng, Olav Bjørn Petersen

“…The implementation process included staff training workshops and development of patient enrollment practice with clarification of expectations and responsibilities, which can be crucial to the results.…”
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Internet and telephone intervention to support patients discontinuing long-term antidepressants in primary care: the REDUCE research programme including RCT by Tony Kendrick, Beth Stuart, Hannah Bowers, Mahboobeh Haji Sadeghi, Helen Page, Christopher Dowrick, Michael Moore, Mark Gabbay, Geraldine Leydon, Guiqing Lily Yao, Shihua Zhu, Paul Little, Gareth Griffiths, Glyn Lewis, Carl May, Joanna Moncrieff, Chris F Johnson, Una Macleod, Simon Gilbody, Rachel Dewar-Haggart, Samantha Williams, Wendy O’Brien, Riya Tiwari, Catherine Woods, Tasneem Patel, Naila Khan, Emma Maund, Nadja van Ginneken, Amy Din, Claire Reidy, Rebecca Lucier, Bryan Palmer, Taeko Becque, Yumna Masood, Natalie Thompson, Ellen van Leeuwen, Marta Glowacka, Adam WA Geraghty

“…A booklet and video version of the patient intervention was also developed in Urdu. Setting Primary care (131 general practices in England and Wales). …”
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Self-reported health and depression among EIRA cohort: a moderated mediation model of sex and perceived social support by Raquel Sánchez-Recio, Raquel Sánchez-Recio, Bárbara Oliván-Blázquez, Bárbara Oliván-Blázquez, Bárbara Oliván-Blázquez, Fátima Méndez-López, Fátima Méndez-López, Fátima Méndez-López, Santiago Gascón-Santos, Santiago Gascón-Santos, Ruth Martí-Lluch, Ruth Martí-Lluch, Ruth Martí-Lluch, Ruth Martí-Lluch, Edurne Zabaleta-Del-Olmo, Edurne Zabaleta-Del-Olmo, Edurne Zabaleta-Del-Olmo, Olaya Tamayo-Morales, Olaya Tamayo-Morales, José A. Maderuelo-Fernández, José A. Maderuelo-Fernández, José A. Maderuelo-Fernández, Marc Casajuana, Tomas López-Jiménez, Emma Motrico, Emma Motrico, Irene Gómez-Gómez, Irene Gómez-Gómez, Álvaro Sánchez-Pérez, Álvaro Sánchez-Pérez, Álvaro Sánchez-Pérez, María Luisa Rodero-Cosano, Joan Llobera, Joan Llobera, Joan Llobera, Juan A. Bellón, Juan A. Bellón, Juan A. Bellón, Juan A. Bellón, Patricia Moreno-Peral, Patricia Moreno-Peral, Bonaventura Bolíbar, Bonaventura Bolíbar, José I. Recio-Rodríguez, José I. Recio-Rodríguez, Rafel Ramos, Rafel Ramos, Rafel Ramos, Rafel Ramos, Ana Clavería, Ana Clavería

“…It is known that having a good social support influences the proper maintenance of health even as a protective factor, besides being a good predictor in the recovery of health during a disease process, influencing differently men and women.AimThis project aims to study the moderating effects of perceived social support in the relationship between depression and self-perceived health according to gender, after a complex multiple-risk intervention was carried out in patients of primary health care with low social support.MethodsA cluster randomized clinical trial was developed in the subgroup of patients included in phase 3 of the EIRA project. …”
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The MinDag app for symptom monitoring and feedback to patients and clinicians during the initial treatment of bipolar disorder – a feasibility study by Margrethe Collier Høegh, Stine Holmstul Glastad, Siv Hege Lyngstad, Magnus Johan Engen, Sofie Ragnhild Aminoff, Ingrid Melle, Thomas Bjella, Trine Vik Lagerberg

“…Abstract Background The app “MinDag” (MyDay) was developed as a tool for monitoring mood, symptoms and illness-relevant behaviour in the initial treatment of bipolar disorder. …”
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Identifying most important predictors for suicidal thoughts and behaviours among healthcare workers active during the Spain COVID-19 pandemic: a machine-learning approach by Itxaso Alayo, Oriol Pujol, Jordi Alonso, Montse Ferrer, Franco Amigo, Ana Portillo-Van Diest, Enric Aragonès, Andrés Aragon Peña, Ángel Asúnsolo Del Barco, Mireia Campos, Meritxell Espuga, Ana González-Pinto, Josep Maria Haro, Nieves López-Fresneña, Alma D. Martínez de Salázar, Juan D. Molina, Rafael M. Ortí-Lucas, Mara Parellada, José Maria Pelayo-Terán, Maria João Forjaz, Aurora Pérez-Zapata, José Ignacio Pijoan, Nieves Plana, Elena Polentinos-Castro, Maria Teresa Puig, Cristina Rius, Ferran Sanz, Cònsol Serra, Iratxe Urreta-Barallobre, Ronny Bruffaerts, Eduard Vieta, Víctor Pérez-Solá, Philippe Mortier, Gemma Vilagut

“…Future clinical implementations of this model could enable the early detection of HCWs at the highest risk for developing adverse mental health outcomes. Study registration NCT04556565 …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…Disseminate the findings and develop a definitive trial bid. Design A programme to develop an enhanced recovery pathway for people with hip fracture and cognitive impairment, tested for implementation and refined in the clinical environment. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…The interview questions were informed by risk perception theories and developed iteratively with our patient and public partners to ensure face validity. …”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…A detailed statistical analysis plan was developed and agreed with the Trial Steering Committee before database lock and analyses. …”
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Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…We assessed the cost-effectiveness of treatments by developing an economic model to estimate the incremental cost per quality-adjusted life-year (QALY) gained. …”
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Opportunities and practices supporting responsive health care for forced migrants: lessons from transnational practice and a mixed-methods systematic review by Amy Robinson, Protus Musotsi, Ziaur Rahman A Khan, Laura Nellums, Bayan Faiq, Kofi Broadhurst, Gisela Renolds, Michael Pritchard, Andrew Smith

“…Cambridge: Polity Press; 2011), to a ‘capability to be healthy’. We developed a tentative set of responsive principles, which we explored through four stakeholder ‘conversations’. …”
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Safety and immunogenicity of GamEvac-Combi, a heterologous rVSV- and rAd5-vectored Ebola vaccine: a randomized controlled multicenter clinical trial in the Republic of Guinea and R... by Denis Y. Logunov, Inna V. Dolzhikova, Mamadou Y. Boiro, Anna V. Kovyrshina, Alina S. Dzharullaeva, Alina S. Erokhova, Daria M. Grousova, Amir I. Tukhvatulin, Fatima M. Izhaeva, Yana V. Simakova, Maria K. Ordzhonikidze, Nadezhda L. Lubenets, Olga V. Zubkova, Dmitrii V. Scheblyakov, Ilias B. Esmagambetov, Maksim M. Shmarov, Alexander S. Semikhin, Natalia M. Tukhvatulina, Dmitrii N. Shcherbinin, Irina L. Tutykhina, Georgiy S. Prokhorov, Alexander A. Khovaev, Tatiana N. Demidova, Nikolai A. Malishev, Liliya N. Merkulova, Olga L. Voronina, Irina T. Fedyakina, Lidiya B. Kisteneva, Lyudmila V. Kolobukhina, Dmitry V. Mishin, Aleksandr L. Elakov, Ekaterina I. Ermolova, Kirill G. Krasnoslobodtsev, Viktor F. Larichev, Irina S. Kruzhkova, Egor M. Burmistrov, Anna B. Sheremet, Elizaveta A. Tokarskaya, Alexander V. Gromov, Dmitrii A. Reshetnikov, Aleksandr I. Fisun, Bogdan N. Kotiv, Dmitrii V. Ovchinnikov, Evgenii V. Ivchenko, Konstantin V. Zhdanov, Sergei M. Zakharenko, Aleksandr N. Solovev, Andrei M. Ivanov, Vitalii S. Sukachev, Roman V. Gudkov, Oleg V. Maltsev, Ilnur A. Gabdrakhmanov, Anton V. Barsukov, Vladislav V. Vashchenkov, Nikolai I. Demianenko, Sergei B. Ignatev, Konstantin V. Asiamov, Nikolai N. Kirichenko, Andrei V. Liubimov, Igor I. Volkov, Evgenii V. Kriukov, Nikolai K. Bazarnov, Viktoriia A. Kolodiazhnaia, Elena V. Kolomoets, Svetlana I. Syromyatnikova, Dmitry E. Chifanov, Alexander F. Andrus, Dmitry A. Kutaev, Sergei V. Borisevich, Boris S. Naroditsky, Alexander L. Gintsburg, Alexander L. Gintsburg

“…There are several licensed vaccines against EVD, but it remains one of the priority diseases for research and development of effective vaccines.MethodsA double-blind randomized placebo-controlled trial was performed to evaluate safety and immunogenicity of rVSV- and rAd5-vectored vaccine GamEvac-Combi in healthy adults of both sexes between 18 and 60 years. …”
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Increase in colonic propionate as a method of preventing weight gain in adults aged 20–40 years: iPREVENT, a multicentre, double-blind, randomised, parallel-group trial by Gary Frost, Joana C Vasconcelos, Jennifer E Pugh, Aisha Anjum, Katerina Petropoulou, George Thom, Louise McCombie, Martina Tashkova, Sumayya Alshehhi, Daphne Babalis, Leah Holroyd, Christina Prechtl, Tom Preston, Mike J Lean, Waljit Dhillo, A Toby Prevost, and Douglas Morrison

“…Background Overweight and obesity affect over 60% of the United Kingdom population and constitute a major risk factor for the development of comorbidities. Preventing weight gain in periods of life where there is an elevated risk of adipose tissue expansion could be beneficial in preventing associated diseases in later life. …”
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Which behavioral patterns score points in taekwondo matches? An analysis of the Roma 2019 World Grand Prix finalists by Yarisel Quiñones Rodríguez, Gennaro Apollaro, Gennaro Apollaro, Carmen Fúnez, Emanuela Faelli, Emanuela Faelli, Antonio Hernández-Mendo, Verónica Morales-Sánchez, Coral Falcó

“…Seven matches were observed (female, n = 3; male, n = 4) for a total of 1,382 registrations. The observation tool used for this study was designed “ad hoc” using the HOISAN tool. …”
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Consequences, costs and cost-effectiveness of workforce configurations in English acute hospitals by Peter Griffiths, Christina Saville, Jane Ball, David Culliford, Jeremy Jones, Francesca Lambert, Paul Meredith, Bruna Rubbo, Lesley Turner, Chiara Dall’Ora

“…The observed association with mortality rates in this study suggests it may not be, and if that is the case, evidence-based methods for determining appropriate staffing need to be developed. Our results not only show the adverse effects of low nurse staffing but also show that medical and AHP staffing are important considerations for patient safety. …”
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EXPERIMENTAL STUDY OF TOXIC PROPERTIES OF VMU-2012-05 DRUG – ORIGINAL NON-NUCLEESIDE INHIBITOR OF HIV-1 REVERSE TRANSCRIPTASE by V. A. Vavilova, E. V. Shekunova, E. A. Jain (Korsakova), V. Yu. Balabanyan, A. A. Ozerov, M. N. Makarova, V. G. Makarov

“…Antiretroviral therapy is currently the main component of treatment for HIV patients. The development of new, more effective and safer drugs is an urgent task.The aim of the research is to study the toxic properties of the finished dosage form (FDF) VMU-2012-05, a non-nucleoside reverse transcriptase inhibitor (1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil) for the HIV-1 infection treatment in single and repeated enteral administrations.Materials and methods. …”
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Intersecting factors of disadvantage and discrimination and their effect on daily life during the coronavirus pandemic: the CICADA-ME mixed-methods study by Carol Rivas, Amanda P Moore, Alison Thomson, Kusha Anand, Zainab Zuzer Lal, Alison Fang-Wei Wu, Ozan Aksoy

“…Strand 2: primary survey and quantitative analysis We developed a new survey for community-dwelling migrants and UK/Republic of Ireland-born children of migrants, also White British comparators, all with/without disability. …”
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Software with artificial intelligence-derived algorithms for detecting and analysing lung nodules in CT scans: systematic review and economic evaluation by Julia Geppert, Peter Auguste, Asra Asgharzadeh, Hesam Ghiasvand, Mubarak Patel, Anna Brown, Surangi Jayakody, Emma Helm, Dan Todkill, Jason Madan, Chris Stinton, Daniel Gallacher, Sian Taylor-Phillips, Yen-Fu Chen

“…Artificial intelligence-based software has been developed to reduce the number of missed or misdiagnosed lung nodules on computed tomography images. …”
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Enhancing referrals to Child and Adolescent Mental Health Services: the EN-CAMHS mixed-methods study by Kathryn M Abel, Pauline Whelan, Lesley-Anne Carter, Heidi Tranter, Charlotte Stockton-Powdrell, Kerry Gutridge, Lamiece Hassan, Rachel Elvins, Julian Edbrooke-Childs

“…The overarching aim of this study is to understand fully what the problems are and how we can develop solutions that can improve the success of Child and Adolescent Mental Health Services referrals. …”
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Exploring meso- and macro-level contextual factors associated with inequalities in program adoption during statewide scale-up of TransformUs Primary, a whole-school physical activi... by Elly Ganakas, Jo Salmon, Jiani Ma, Karen E. Lamb, Lisa Barnett, Adrian Bauman, Amanda Telford, Nicola D. Ridgers, Anna Timperio, Harriet Koorts

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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…A comprehensive search was developed iteratively and undertaken in a range of relevant bibliographic databases and other source. …”
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