Predicting Deterioration in Patients With Normotensive Acute Pulmonary Embolism Using Clinical‐Imaging Features: A Multicenter Prospective Cohort Study by Yizhuo Gao, Shibo Wei, Yuchen Liu, Zhenglun Yu, Shanshan Zhan, Binze Yang, Chuanxin Qi, Shougang Qi, Minggang Wang, Dong Jia

“…Background Prioritization of management strategies in patients with normotensive acute pulmonary embolism is based on the identification of individuals at risk for early deterioration. This study aims to develop and validate a novel score for deterioration prediction using clinical‐imaging features. …”
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Identifying patients with cerebral infarction within the time window compatible with reperfusion therapy, diagnostic performance of glutathione S-transferase-π (GST-π) and peroxire... by Nicolas Girerd, Arif Karakus, Jean-Charles Sanchez, Sophie Marchal, Anne Aubertin, Sanae Bouali, Kevin Duarte, Sandrine Reymond

“…If confirmed, these molecules could be used to develop rapid and reliable decentralised measurement methods, making it possible to initiate reperfusion therapy before hospital admission. …”
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Multicentre, 26-week, open-label phase 2 trial of the JAK inhibitor filgotinib in Behçet’s disease, idiopathic inflammatory myopathies and IgG4-related disease: DRIMID study protoc... by Sander W Tas, Joost Raaphorst, Paco M J Welsing, Jacob M van Laar, Rogier M Thurlings, Robbert J Goekoop, César Magro Checa, Jan A M van Laar, Bettina C Geertsema-Hoeve, Nicolle H Rekers, Erik Present

“…Thus, there is an urgent need to develop more targeted and effective anti-inflammatory treatments. …”
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Randomised, placebo-controlled, double-blinded, four-way crossover trial to demonstrate the comparative pharmacodynamic equivalence of a non-invasive diagnostic test for adrenal in... by Judith Cohen, Miguel Debono, Kathleen Baster, Richard J Ross, Charlotte J Elder, Kathryn L Date, Sharon L Caunt, Jane Fearnside, Trevor N Johnson, Rosie N Taylor

“…A novel formulation, Nasacthin, has been developed, which can be delivered intranasally, with the resultant glucocorticoid levels measured in saliva instead of blood. …”
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Coproduction in Social Prescribing Initiatives: Protocol for a Scoping Review by Madeline Dougherty, Tamara Tompkins, Elaine Zibrowski, Jesse Cram, Maureen C Ashe, Le-Tien Bhaskar, Kiffer George Card, Christina Godfrey, Paul Hebert, Ron Lacombe, Caitlin Muhl, Kate Mulligan, Gillian Mulvale, Michelle L A Nelson, Myrna Norman, Bobbi Symes, Gary Teare, Vivian Welch, Anita Kothari

“…We anticipate this review will guide clients, communities, stakeholders, and policy makers in further developing SP practice within health care systems. …”
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Inspiratory muscle training facilitates liberation from mechanical ventilation in subacute critically ill patients—a randomized controlled trial by Shu-Jane Wang, Tien-Pei Fang, Tien-Pei Fang, Daniel D. Rowley, Nan-Wei Liu, Jui-O Chen, Jui-Fang Liu, Jui-Fang Liu, Hui-Ling Lin, Hui-Ling Lin, Hui-Ling Lin

“…BackgroundPatients undergoing mechanical ventilation often develop rapid diaphragmatic atrophy, respiratory muscle weakness, and dysfunction, which are associated with prolonged duration of ventilation. …”
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Differences in the incidence and mortality of tracheal, bronchus, and lung cancer between the Global Cancer Observatory 2022 and the Global Burden of Disease 2021 by Zhifei Li, Runze Li, Jianchuan Chen, Ruida Yang, Peng Li, Bin Qiu

“…Additionally, some populous developing countries, including China, South Africa, Brazil and India, showed smaller differences in ASRs. …”
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Prevalence of hematological malignancies in Africa: A systematic review and meta-analysis by Zewudu Mulatie, Dereje Mengesha Berta, Alemu Gedefie, Hussen Ebrahim, Brukitawit Eshetu, Tesfaye Gessese, Mihret Tilahun, Seada Ali, Habtu Debash, Yeshimebet Kassa, Ermiyas Alemayehu

“…Abstract Hematological malignancies are a class of neoplasms that include a variety of diverse diseases that all develop from and change into lymphatic and bone marrow cells. …”
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Blinding assessment in randomised sham-controlled trials of acupuncture:protocol for a systematic survey by Ling Li, Xin Sun, Jiali Liu, Minghong Yao, Yong Fu, Jiahui Yang, Xiaochao Luo

“…The findings of this study will be disseminated through peer-reviewed publications, conference presentations and condensed summaries for clinicians, health policymakers and guideline developers regarding the design, conduct, analysis and interpretation of blinded assessment of sham acupuncture RCTs.Study registration Open Science Framework (https://doi.org/10.17605/OSF.IO/B3U7K).…”
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Tripartite prehabilitation of patients with acute myeloid leukaemia and high-risk myelodysplastic syndromes during intensive chemotherapy before allogeneic haematopoietic stem cell... by Jean-Marie Boher, Norbert Vey, Colombe Saillard, Sarah Cuvelier, Charlène Villaron-Goetgheluck, Leonor Almeida-Lopez, Anne-Gaelle Le Corroller, Pauline Denis, Céline Rivieccio, Sarah Calvin, Cécile Bannier-Braticevic

“…Furthermore, allo-HSCT can be responsible for significant toxicity with risks of graft-versus-host disease (GvHD). Developing strategies to prevent physical deconditioning, undernutrition and psychological distress could help maintain a satisfactory general state of health before transplantation and thus limit these deleterious effects. …”
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Comparison of the inflammatory biomarkers IL- 6, TNF-α, and CRP to predict the effect of nutritional therapy on mortality in medical patients at risk of malnutrition by Carla Wunderle, Elisabeth Martin, Alma Wittig, Pascal Tribolet, Thomas A. Lutz, Christina Köster-Hegmann, Zeno Stanga, Beat Mueller, Philipp Schuetz

“…This finding might help to develop improved treatment strategies for patients with elevated inflammatory profiles. …”
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Incidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study by John Wogabaga, Kathy Burgoine, Abel Kakuru, Brendah Nambozo, Martin Chebet, Josephine Tumuhamye, Benon Wanume, Faith Oguttu, Milton W. Musaba, Agnes Napyo, Solomon Wani, Peter Olupot-Olupot, Andrew D. Weeks, Thorkild Tylleskär, David Mukunya

“…Neonates born at home were twice as likely to develop omphalitis as those born in a health facility (adjusted hazards ratio (AHR) 1.99; 95% CI: 1.01, 3.9). …”
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Supporting vulnerable families’ meal practices: process evaluation of a nationwide intervention implemented by a retailer and social organizations by Marjolijn Vos, Anneleen Van Kerckhove, Benedicte Deforche, Viktor L. J. Proesmans, Nathalie Michels, Maartje P. Poelman, Maggie Geuens, Wendy Van Lippevelde

“…The objective of this study was to evaluate a nationwide intervention “Dinner is served at 1-2-3 euros”, developed by a Belgian retailer in collaboration with social organizations. …”
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Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Stu... by Haobin Peng, Jiajun Wen, Manli Chen, Zhengyuan Xia, Ying Jiang, Kaiqi Xie, Weitao Huang, Bangsheng Cui, Peixing Li, Yiwen Zhang, Xianping Wu

“…This single-center, randomized controlled, observer-blinded trial utilizes a novel combination of liposomal bupivacaine (LB) single-injection PENG block to examine its efficacy, duration, and safety in preoperative analgesia for hip fractures, aiming to develop a new preoperative analgesic protocol. Methods Sixty-six patients with hip fractures received ultrasound-guided single-injection PENG block with LB or ropivacaine after admission. …”
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Prediction model study focusing on eHealth in the management of urinary incontinence: the Personalised Advantage Index as a decision-making aid by Huibert Burger, Henk van der Worp, Marco H Blanker, Marjolein Y Berger, Anne Martina Maria Loohuis, Nienke Wessels, Janny Dekker, Alec GGA Malmberg

“…Objective To develop a prediction model and illustrate the practical potential of personalisation of treatment decisions between app-based treatment and care as usual for urinary incontinence (UI).Design A prediction model study using data from a pragmatic, randomised controlled, non-inferiority trial.Setting Dutch primary care from 2015, with social media included from 2017. …”
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Inheritance of Drought Tolerance in a F₃ Biparental Population of Pinto Saltillo (<i>Phaseolus vulgaris</i> L.) × Tepary Cafe (<i>Phaseolus acutifolius</i> A. Gray) by Marcela Cília-García, José Cruz Jiménez-Galindo, Cecilia Beatriz Peña-Valdivia, Ebandro Uscanga-Mortera, Antonio García-Esteva, Daniel Padilla-Chacón

“…The main objective of this study was to evaluate the germination and seedling growth components in response to drought stress simulated with polyethylene glycol (PEG-6000). We developed a F₃ biparental population from the cross between the susceptible P-saltillo variety and drought-tolerant T-cafe, which allowed the study of drought-tolerance genetics in beans. …”
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Cluster randomised controlled trial to investigate the effectiveness and cost-effectiveness of a Structured Health Intervention For Truckers (the SHIFT study): a study protocol by Mark Hamer, Laura J Gray, Gerry Richardson, Vicki Johnson, Stacy A Clemes, Verónica Varela Mato, Fehmidah Munir, Charlotte L Edwardson, Yu-Ling Chen, Nishal Bhupendra Jaicim, Jacqui Troughton

“…Their working environments are not conducive to a healthy lifestyle, yet there has been limited attention to health promotion efforts. We have developed a Structured Health Intervention For Truckers (the SHIFT programme), a multicomponent, theory-driven, health-behaviour intervention targeting physical activity, diet and sitting in HGV drivers. …”
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Parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: outcomes from LOCATE-NAFLD by Sanjeewa Kularatna, James O'Beirne, Adrian Barnett, Patricia C Valery, Elizabeth Powell, Ingrid J Hickman, Ruth Tulleners, David Brain, Katherine Stuart, Carolyn McIvor, Elen Witness, Melanie Aikebuse

“…Other clinical outcomes showed minimal changes.Conclusion The LOCATE model shows potential for impact, particularly in reducing waiting times for patients at high risk of developing severe liver disease due to NAFLD. A larger sample and longer follow-ups are needed to measure additional clinical outcomes.Trial registration number ACTRN12620000158965.…”
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Effects of urban airborne particulate matter exposure on the human upper respiratory tract microbiome: a systematic review by Sonia Arca-Lafuente, Beatriz Nuñez-Corcuera, Rebeca Ramis, Spyros Karakitsios, Denis Sarigiannis, Saúl García Dos Santos, Amanda Fernández-Rodríguez, Verónica Briz

“…In summary, the entry of fine and coarse particles into the URT is associated with microbial dysbiosis, increasing the risk of developing respiratory diseases and allergies. Prospero registration: This systematic review was registered on PROSPERO (#CRD42023416230) Graphical Abstract…”
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Recovery rate of sever acute malnutrition and its predictors among children admitted to therapeutic feeding unit in Northcentral Ethiopia by Gebrehiwot Berie Mekonnen, Wubet Tazeb Wondie, Bruck Tesfaye Legesse, Netsanet Melkamu Abera, Abere Gebru Abuhay, Gebrie Kassaw Yirga, Biruk Demissie, Melaku Tadege Engidaw

“…Abstract Severe acute malnutrition (SAM) is the leading cause of hospital admissions and continues to be the leading cause of death in pediatric wards for children under five (25–30% of deaths), particularly in developing nations. Even if Ethiopia implements SAM treatment guidelines and protocols, the study area needs to have up-to-date data on the recovery rate. …”
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