Prior information guided deep-learning model for tumor bed segmentation in breast cancer radiotherapy by Peng Huang, Hui Yan, Jiawen Shang, Xin Xie

“…To facilitate this process, a deep learning model is developed to segment TB from CT with the guidance of prior tumor location. …”
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Focused low-intensity hippocampal transcranial ultrasound stimulation (TUS) for sleep disturbances in patients with chronic tinnitus: A study protocol for a pilot randomized contro... by Xi Ni, Yuk Shan Yuen, Zeyan Li, Kaipeng Wang, Natalie Shu Yang, Yi Yuan, Lin Meng, Liwei Guo, Hanna Lu

“…Compared to TMS, focused low-intensity transcranial ultrasound stimulation (TUS) is a newly developed modality of non-invasive brain stimulation that offers promising therapeutic effects by transmitting acoustic energy into deep brain structures with a high spatial resolution (i.e., sub-millimeter), which sparks interest in managing the comorbidities in ageing populations.…”
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Paediatric goal management training in patients with acquired brain injury: study protocol for a randomised controlled trial by Eva Skovlund, Ruth Elizabeth Hypher, Anne Elisabeth Brandt, Kari Risnes, Torstein Baade Rø, Stein Andersson, Torun Gangaune Finnanger, Jan Stubberud

“…The purpose of the present study is to determine the efficacy of a recently developed paediatric version of GMT (pGMT) for children and adolescents with ABI and reported executive dysfunction.Methods and analysis This study protocol describes a parallel randomised controlled trial including allocation concealment and assessor blinding. …”
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Dynamic Simulation Models of Suicide and Suicide-Related Behaviors: Systematic Review by Genevieve Gariepy, Rifat Zahan, Nathaniel D Osgood, Benjamin Yeoh, Eva Graham, Heather Orpana

“…MethodsEight databases were searched, including MEDLINE, Embase, PsycINFO, Scopus, Compendex, ACM Digital Library, IEEE Xplore, and medRxiv, from inception to July 2023. We developed a search strategy in consultation with a research librarian. …”
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The effects of physical activity on mental health in adolescents with attention-deficit hyperactivity disorder: a randomized controlled trial by Chang Liu, Yijian Yang, Stephen Heung-sang Wong, Andes Leung, Cindy Hui-ping Sit

“…Abstract Background Adolescents with attention-deficit hyperactivity disorder (ADHD) represent a high-risk population with an elevated likelihood of developing mental health disorders. Physical activity (PA) has emerged as a promising intervention to enhance mental health in youth. …”
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Incidence and influencing factors of occupational pneumoconiosis: a systematic review and meta-analysis by Xiao Yu, Xinri Zhang, Xuesen Su, Xiaomei Kong

“…Studies were selected for meta-analysis if they involved at least one variable investigated as an influencing factor for the incidence of pneumoconiosis and reported either the parameters and 95% CIs of the risk fit to the data, or sufficient information to allow for the calculation of those values.Primary outcome measures The pooled incidence of pneumoconiosis and risk ratio (RR) and 95% CIs of influencing factors.Results Our meta-analysis included 19 studies with a total of 335 424 participants, of whom 29 972 developed pneumoconiosis. The pooled incidence of pneumoconiosis was 0.093 (95% CI 0.085 to 0.135). …”
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Assessment of Geriatric Problems and Risk Factors for Delirium in Surgical Medicine: Protocol for Multidisciplinary Prospective Clinical Study by Henriette Louise Möllmann, Eman Alhammadi, Soufian Boulghoudan, Julian Kuhlmann, Anica Mevissen, Philipp Olbrich, Louisa Rahm, Helmut Frohnhofen

“…ObjectiveThis study aimed to determine the frequency and severity of geriatric medical problems in elective patients of the Clinics of Oral and Maxillofacial Surgery, Vascular Surgery, and Orthopedics, General Surgery, and Trauma Surgery, revealing associations with the incidence of perioperative delirium regarding potential risk factors, and recording the long-term effects of geriatric problems and any perioperative delirium that might have developed later the patient’s life. MethodsWe performed both pre- and postoperative assessments in patients of 4 different surgical departments who are older than 70 years. …”
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Cluster-randomized trial of the implementation of the Responses to Illness Severity Quantification (RISQ) system in children with acute malnutrition 6 to 59 months of age in Ngouri... by Nancy M. Dale, Youssouf Djidita Hagre, Susan Shepherd, George Tomlinson, Stanley Zlotkin, Masra Ngaradoum, Mahmat Bechir, Marius Madjissem, Charles Tehoua, Christopher Parshuram

“…Abstract Background The Responses to Illness Severity Quantification (RISQ) System is a scientifically developed clinical decision support tool comprised of four parts: (1) a validated 7-item severity of illness score, (2) age-specific documentation forms, (3) context-relevant score-matched recommendations, and (4) implementation programming. …”
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Prognostic role of preoperative inflammatory markers in postoperative lung metastasis of colorectal cancer: a retrospective study by Jiukang Sun, Weili Xiong, Zhang Fang, Chuanjun Song

“…Results Among the patients, 55 developed lung metastasis during the study period. …”
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Comparative Analysis of Muscle Elasticity and Pathological Characteristics Between Affected and Unaffected Sides in Postherpetic Neuralgia Patients: Protocol for a Pilot Cohort Tra... by Ji H, Ma J, Cui X, Huang Y

“…Heyu Ji,1 Jiangyu Ma,2 Xulei Cui,1 Yuguang Huang1 1Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, People’s Republic of China; 2Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, People’s Republic of ChinaCorrespondence: Xulei Cui; Yuguang Huang, Department of Anesthesiology, Peking Union Medical College Hospital, Shuaifuyuan 1st, Dongcheng District, Beijing, 100730, People’s Republic of China, Email cuixulei10685@pumch.cn; garypumch@163.comBackground: Postherpetic neuralgia (PHN) is the most common condition that can develop as a complication after herpes zoster (HZ) infection, characterized by pain that persists for more than 3 months after the initial rash has resolved. …”
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Depression among medical students in Bangladesh: a systematic review and meta-analysis protocol on prevalence and associated factors by Sharmin Sultana, Afroza Tamanna Shimu, Imtiaz Abdullah, Md Mantaka Rahman, Ummul Khair Alam, Nusrat Fatema

“…The quality of the included studies will be assessed using the modified Newcastle-Ottawa Scale (mNOS) tool developed for observational study designs. All statistical analyses and visualization will be conducted using the R studio v.4.3.2 with built-in “meta”-packages and GraphPad Prism v.9.0.2.Ethics and dissemination This review will analyse existing published evidence. …”
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Randomised, placebo-controlled, double-blinded trial of fecal microbiota transplantation in severe obesity: a study protocol by Rasmus Goll, Per-Christian Valle, Hege Marie Hanssen, Maria Serafia Fjellstad, Linn Skjevling, Peter Holger Johnsen, Kristin Helen Almå

“…The enema method for FMT administration used in this study was developed by our study team.Trial registration number NCT03273855.…”
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Improving cervical cancer screening participation by introducing HPV vaginal self-sampling to women living with HIV in Denmark– a pilot study by Siri Nana Halling Svensgaard, Mette Tranberg, Berit Andersen, Lone Kjeld Petersen, Merete Storgaard, Sanne Jespersen

“…Women living with HIV (WLWH) are at a six-fold higher risk of developing cervical cancer, primarily due to persistent infection with high-risk HPV (hrHPV). …”
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[195mPt]Cisplatin for lung cancer imaging: a pilot study by Denise S. Hoogenkamp, Berlinda J. de Wit-van der Veen, Jeske Hendriksen, Karlijn van der Schilden, Josefine A. M. Nanne, José S.A. Belderbos, Maddalena M. Rossi, Martien P. J. Mooijer, Uta Funke, N. Harry Hendrikse, Wouter V. Vogel, Else A. Aalbersberg

“…Abstract Background Radiolabeled [195mPt]cisplatin has been developed as a tool to determine the biodistribution of cisplatin in vivo through SPECT imaging and possibly aid in patient-selection. …”
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Socio-economic assessment of dog population management systems: a scoping review by Rabina Ghimire, Parimala Mohanty, Elly Hiby, Andrew Larkins, Andrew Larkins, Salome Dürr, Sonja Hartnack

“…Prioritizing systematic collection of data on costs, benefits and social impacts allows for a more robust analysis of DPM systems. Developing tools and standardized reporting methods would further facilitate consistent evaluation of impacts, efficient resource allocation and evidence-based policy making to implement the most cost-effective DPM systems.Systematic review registrationDOI: 10.17605/OSF.IO/NHE3X…”
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Improvement of Care Cascade for Hypertension and Diabetes in Rural China: Protocol for an Implementation Study by Xuejun Yin, Zhenzhong Wang, Jingsong Yang, Jia Li, Shasha Han, Wenshuai Feng, Qinglan Liu, Ning Li, Lihui Zhang, Jiawen Ke, Xiaoxia Wei, Juan Zhang, Nizal Sarrafzadegan, Ruitai Shao

“…Intervention villages will implement interventions developed in Phase 2 for 1 year, while control villages will continue with usual care. …”
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Improving older people’s experiences and safety at transitions of care: the PACT mixed-methods study including RCT by Jenni Murray, Ruth Baxter, Jane O’Hara, Laura Sheard, Catherine Hewitt, Natasha Hardicre, Charles Vincent, Eirini Oikonomou, Gerry Richardson, Rosie Shannon, Kalpita Baird, Stephen Brealey, Robbie Foy, Laura Mandefield, Sarah Hampton, Ed Breckin, Lubena Mirza, Alfredo Palacios, Sally Moore, Jayne Marran, Jacqui Elliot, Jane Schofield, Alison Cracknell, Beth Woods, Sarah Cockayne, Thomas Mills, Yvonne Birks, Olivia Joseph, Rebecca Lawton

“…The methodology of fidelity assessments for complex healthcare interventions requires further development. Trial registration This trial is registered as Current Controlled Trials ISRCTN51154948 (WP5) and ISRCTN17062524 (WP6). …”
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PEP4LEP study protocol: integrated skin screening and SDR-PEP administration for leprosy prevention: comparing the effectiveness and feasibility of a community-based intervention t... by Stephen E Mshana, Jan Hendrik Richardus, Liesbeth Mieras, Artur Manuel Muloliwa, Anne Schoenmakers, Thomas Hambridge, Robin van Wijk, Christa Kasang, Kidist Bobosha, Fernando Mitano, Ephrem Mamo, Abdoulaye Marega, Nelly Mwageni, Taye Letta, Deus Vedastus Kamara, Ahmed Mohammed Eman, Litos Raimundo, Blasdus Njako

“…Post-exposure prophylaxis with single-dose rifampicin (SDR-PEP) reduces the risk of developing leprosy when administered to screened contacts of patients. …”
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Pilot study to evaluate the use of remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): study prot... by James M Cotton, Derek Kyte, Nazish Khan, Winnie Chua, Larissa Fabritz, Richard P Steeds, Yongzhong Sun, Samir Mehta, Katie Kirkham, Philip Collis, Clive Stubbs, Mary Nulty

“…Introduction Aortic stenosis (AS) is common affecting >13% of adults over the age of 75 years. In people who develop symptoms, without valve replacement, prognosis is dismal with mortality as high as 50% at 1 year. …”
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A score prediction model for predicting the heterogeneity symptom trajectories among lung cancer patients during perioperative period: a longitudinal observational study by Yong Yang, Xueqi Tian, Huiling Zhou, Yichao Wang, Yifeng Gu, Ao Qi, Decai Wang, Zhiying Wang, Yabin Gong, Lijing Jiao, Ling Xu

“…By Logistic regression analysis, a score prediction model was developed based on predictive factors, which was internally validated utilizing 1000 bootstrap samples. …”
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