School-Based Health Centers Addressing Health Equity for LGBTQ + Patients (SBHCs HELP): protocol for a stepped-wedge trial to implement innovations promoting structural competency... by Cathleen E. Willging, Daniel Shattuck, Marisa Sklar, Rachel A. Sebastian, Robert L. Stout, Mary M. Ramos

“…Nationally recognized guidelines for nurturing structural competency include (1) adopting, disseminating, and adhering to SGD supportive policies and procedures; (2) creating welcoming physical environments; (3) systematically documenting and using sexual orientation and gender identity information in clinical care; (4) training all employees in best practices for interacting with SGD patients; and (5) developing the clinical workforce to deliver high-quality services to SGD patients. …”
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The feasibility, acceptability and clinical impact of a guided self-help mobile intervention (INTERconNEcT-EDs) for individuals with eating disorders: protocol for two multicenter... by Gianluca Lo Coco, Gaia Albano, Salvatore Gullo, Valentina Cardi, Cristina Segura-Garcia

“…INTERconNEcT-EDs) to target psychological distress and eating psychopathology in young adults with ED symptoms has been developed. INTERconNEct-EDs is an online, eight-week, guided self-help (GSH) program based on an integrated approach which combines elements of psychoeducation, behaviour change and interpersonal therapy tailored to individual’s interpersonal difficulties. …”
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Status and perceptions of ChatGPT utilization among medical students: a survey-based study by Na Hu, Xiao Qin Jiang, Yi Da Wang, Yan Ming Kang, Zhen Xia, Hao Hui Chen, Sai Nan Duan, Dong Xu Chen

“…Trial registration Not applicable.…”
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HOLSEA-NL: a Holocene water level and sea level indicator dataset for the Netherlands by K. de Wit, K. M. Cohen, R. S. W. van de Wal, R. S. W. van de Wal

“…<p>Deltas and coastal plains worldwide developed under the influence of relative sea level rise (RSLR) during the Holocene. …”
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Association of Cumulative Exposure to Triglyceride and Remnant Cholesterol With the Risk of Cardiovascular Disease in Hypertensive Patients With Target LDL‐C by Shuang Guo, Chi Wang, Taoyu Hu, Lihua Lan, Zhen Ge, Jianxiang Huang, Shuohua Chen, Shouling Wu, Hao Xue

“…During a median follow‐up of 15.97 years, 1415 participants developed CVD. After multivariable adjustment, compared to the low cumTG/low cumRC group, CVD risk was higher in the high cumTG/high cumRC (HR 1.43, 95% CI 1.24‒1.64) and low cumTG/high cumRC groups (HR 1.24, 95% CI 1.05–1.47), but not in the high cumTG/low cumRC group (HR 1.06, 95% CI 0.89–1.25). …”
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Safety and tolerability of metformin in overweight and obese patients with dengue: An open-label clinical trial (MeDO). by Nguyet Minh Nguyen, Dong Thi Hoai Tam, Ho Quang Chanh, Huynh Trung Trieu, Nguyen Thi Xuan Chau, Nguyen Thanh Van, Nguyen Thanh Phong, Cao Thi Tam, Nguyen Thi Hong Lan, Luong Thi Hue Tai, Nguyen Thi Cam Huong, Le Thi Ngoc Thuan, Nguyen Van Hao, Phan Tu Qui, Tran Thi Dong Vien, Pham Thi Hai Men, Huynh Thi Thuy Hoa, Phan Vinh Tho, Huynh Thi Le Duyen, Vi Tran Thuy, Thuan Dang Trong, Nguyen Tan Thanh Kieu, Angela McBride, Evelyne Kestelyn, Ronald B Geskus, Nguyen Lam Vuong, Sophie Yacoub

“…Six patients in the metformin group and 5 controls developed dengue shock syndrome, and no patients died. …”
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Determinants of prenatal breastfeeding knowledge, attitudes and self-efficacy among Burmese migrant pregnant mothers in Samut Sakhon Province, Thailand: a cross-sectional study by Montakarn Chuemchit, Zayar Lynn

“…A comprehensive understanding of these factors will enable policy-makers and healthcare providers to develop context-specific interventions for the promotion of exclusive breast feeding among Burmese migrant mothers in Thailand.Trial registration number TCTR20230310004.…”
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A systematic review of robotic colorectal surgery programs worldwide and a comprehensive description of local robotic training programme by Valentin Butnari, Harpreet Kaur Sekhon Inderjit Singh, Eshtar Hamid, Shady Gaafar Hosny, Sandeep Kaul, Joseph Huang, Richard Boulton, Nirooshun Rajendran

“…In addition it delineates the conceptualization and implementation of a locally developed RACS program tailored to senior colorectal trainees and fellows at our Trust. …”
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Risk factors for urosepsis following ureteroscopic lithotripsy: a systematic review and meta-analysis by Lifei Dai, Junlian Xiang, Xiaoli Liu, Xiaoyan Wen, Lin Tan, Jiali Zhang

“…Early identification of the factors influencing urosepsis is crucial to reduce its incidence and improve patient outcomes.Systematic Review RegistrationPROSPERO CRD42025641787.…”
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Accuracy and reliability of a three-dimensional superimposition method for maxillary jaws and dentition by Qifei Yang, Minchun Cai, Shushu Hao, Huihan Chu, Yuting Wang, Ming Hu, Hui Yang, Zhendong Wang

“…Abstract Objective This study aims to develop a method for three-dimensional (3D) superimposition of the maxillary jaws and dentition using Cone Beam Computed Tomography (CBCT) and intraoral scan data, and to evaluate its accuracy and reliability. …”
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Internet-Based Interventions for Preventing Premature Birth in Preconceptional Women of Childbearing Age: Systematic Review by Sun-Hee Kim, Sun-Young Jung, Jin-Hwa Park, Jennie C De Gagne

“…Future research, including robust clinical trials, is essential to develop, evaluate, and disseminate effective and safe internet-based interventions for preconception care. …”
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Adherence to outpatient cardiac rehabilitation and related factors in STEMI after PCI in China: a sequential explanatory mixed method study protocol by Wenjie Zhang, Hongjin Wang, Peiru Li, Beibei Wu, Xiaodong Wang

“…The final phase links to integrating the data and developing a targeted strategy to improve adherence to outpatient cardiac rehabilitation among patients with ST-elevation myocardial infarction after percutaneous coronary intervention. …”
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Unveiling the perfect workout: exercise modalities and dosages to ameliorate adipokine dysregulation in individuals with overweight and obesity: a systematic review with pairwise,... by Hai Wang, Hao Wang, Enyan Zhan, Xiaodong Liu

“…These abnormalities are closely linked to an increased risk of developing type 2 diabetes mellitus (T2DM), cardiovascular diseases, and certain cancers.ObjectiveTo systematically evaluate the effects of different exercise modalities—AE, RT, COM, HIIT—and their dosages on the regulation of adipokines (leptin and adiponectin) in individuals with overweight and obesity.MethodsA comprehensive literature search was conducted across Cochrane, Embase, PubMed, Web of Science, and EBSCO databases for randomized controlled trials (RCTs) published between 2000 and January 2025. …”
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Effectiveness of Virtual Simulations Versus Mannequins and Real Persons in Medical and Nursing Education: Meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trial... by Nan Jiang, Yuelun Zhang, Siyu Liang, Xiaohong Lyu, Shi Chen, Xiaoming Huang, Hui Pan

“… BackgroundVirtual simulation (VS) is a developing education approach with the recreation of reality using digital technology. …”
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AN INDIVIDUALIZED RISK ASSESSMENT OF SUDDEN CARDIAC DEATH IN DILATION CARDIOMYOPATHY PATIENTS by T. G. Vaykhanskaya, L. N. Sivitskaya, T. V. Kurushko, N. G. Danilenko, O. P. Melnikova, A. V. Frolov

“…With binary logit-regression analysis of independent risk factors (VES, sVT, mATW, TCR, JTd and GLS LV) we built-up a model of binary regression (F=31,2; χ2=143,2; p=0,0000) and developed an algorithm of SCD risk evaluation that make it to classify with high prediction power up to 93,9%, cases of DCMP (OR 470; sensitivity 80,8%, specificity 99,1%).Conclusion. …”
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Cost-Effectiveness Analysis of a Machine Learning–Based eHealth System to Predict and Reduce Emergency Department Visits and Unscheduled Hospitalizations of Older People Living at... by Charlotte Havreng-Théry, Arnaud Fouchard, Fabrice Denis, Jacques-Henri Veyron, Joël Belmin

“…After each home visit, the home care aides completed a questionnaire on participants’ functional status using a smartphone app, and the information was processed in real time by a previously developed machine learning algorithm that identifies patients at risk of an emergency visit within 7 to 14 days. …”
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Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, doub... by Niklas Walther, Robert Schultz-Heienbrok, Heino Staß, Victor M Corman, Nils C Gassen, Marcel A Müller, Christian Drosten, Martin Witzenrath, Hweeling Lee, Maximilian G Posch

“…A liquid oral formulation using polyethylene glycol 400 was developed and investigated in healthy volunteers to assess safety, tolerability, and pharmacokinetics in comparison to the marketed tablet. …”
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Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and Delta va... by Timothy W Russell, Hermaleigh Townsley, Sam Abbott, Joel Hellewell, Edward J Carr, Lloyd A C Chapman, Rachael Pung, Billy J Quilty, David Hodgson, Ashley S Fowler, Lorin Adams, Chris Bailey, Harriet V Mears, Ruth Harvey, Bobbi Clayton, Nicola O'Reilly, Yenting Ngai, Jerome Nicod, Steve Gamblin, Bryan Williams, Sonia Gandhi, Charles Swanton, Rupert Beale, David L V Bauer, Emma C Wall, Adam J Kucharski

“…Using data from a prospective observational cohort study of healthy adult volunteers undergoing weekly occupational health PCR screening, we developed a Bayesian hierarchical model to reconstruct individual-level viral kinetics and estimate how different factors shaped viral dynamics, measured by PCR cycle threshold (Ct) values over time. …”
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Pharmacokinetic and pharmacodynamic assessment of oral nicotinamide in the NEAT clinical trial for early Alzheimer’s disease by Gabriel L Ketron, Felix Grun, Joshua D Grill, Howard H Feldman, Robert A Rissman, Gregory J Brewer

“…Both the bioavailability and rapid metabolic methylation need to be addressed if nicotinamide is further developed as a potential intervention for AD. Trial registration NCT03061474, last updated 2023–10-17. https://clinicaltrials.gov/study/NCT03061474 .…”
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Measurement, determinants and outcomes of maternal care satisfaction in Nigeria: a systematic review by Jane E Hirst, Robyn Norton, Margaret Peden, Edward Mullins, Beatrice Wuraola Ope, Tavleen Wasan

“…It also highlights the need for robust methodologies that accurately measure women’s experiences, which is essential for enhancing the quality of maternal health services.PROSPERO registration number A protocol was developed for this study and published on PROSPERO, the International Prospective Register of Systematic Reviews (CRD42023414771).…”
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