East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol by Michael Doherty, Roshan das Nair, Ana Valdes, Reuben Ogollah, Paul Greenhaff, Bonnie Millar, Michelle Hall, Amy Fuller, Polykarpos Angelos Nomikos, David A Walsh, A Abhishek

“…However, implementation of these in primary care is often suboptimal. This study aims to develop a complex intervention with non-pharmacological and pharmacological components that can be delivered by nurses. …”
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Factors impacting loneliness in patients with serious life-limiting illness in the Emergency Medicine Palliative Care Access (EMPallA) study by Brendan Maloney, Mara Flannery, Jason J. Bischof, Kaitlyn Van Allen, Oluwaseun Adeyemi, Keith S. Goldfeld, Allison M. Cuthel, Alex Chang, Corita R. Grudzen

“…Discerning risk factors of loneliness in palliative care patients allows providers to take preventative action and develop holistic treatment plans. Methods A planned sub-study of patients who completed the previously developed Three-Item Loneliness Scale upon enrollment into the multicenter, randomized clinical trial Emergency Medicine Palliative Care Access (EMPallA) with the objective of investigating the association of multimorbidity with loneliness in patients with late-stage illnesses. …”
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Acupoint catgut embedding advantage in treating gastro-oesophageal reflux disease (ACE-GERD): study protocol for a randomised controlled trial by Xiaofeng Lin, Shuting Wen, Xiying Zhao, Zhaoli Fu, Shumin Qin, Qimou Pan, Fengbin Liu, Wenfang He, Tianwen Liu

“…Background Gastro-oesophageal reflux disease (GERD) is a highly prevalent disorder worldwide and developing effective treatment strategies for GERD is a clinical priority. …”
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The Ohio State University Early Psychosis Intervention Center (EPICENTER) step-based care programme for individuals at clinical high risk for psychosis: study protocol for an obser... by Nicholas J K Breitborde, Hossam Guirgis, Walter Stearns, Kristen M Carpenter, Ghada Lteif, Jacob G Pine, Nichole Storey, Heather Wastler, Aubrey M Moe

“…Introduction In October 2018, the Substance Abuse and Mental Health Services Administration funded 21 sites throughout the USA to develop, implement and evaluate specialised care programmes for individuals at clinical high risk for developing a psychotic disorder (CHR-P). …”
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Identifying psychosocial characteristics that predict outcome to the UPLIFT programme for people with persistent back pain: protocol for a prospective cohort study by Pim Cuijpers, Hayley Thomson, Jonathon Dearness, John Kelley, Kylie Conway, Collette Morris, Leanne Bisset, Gwendolijne Scholten-Peeters, Michel W Coppieters

“…Prognostic models will be developed using multivariable logistic regression analyses, with bootstrapping techniques for internal validation. …”
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Perspectives and Experiences of Family Caregivers Using Supportive Mobile Apps in Dementia Care: Meta-Synthesis of Qualitative Research by Haifei Shen, Yi Han, Wen Shi, Jiangxuan Yu, Xueqi Shan, Hongyao Wang, Junjie Wang

“…Overall, our study offers an important reference for developing person-centered supportive mobile apps for family caregivers of persons with dementia. …”
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Improving retention of pediatric feeding tubes with a nasal bridle: a randomized controlled trial by Megan Foster, Veronica Armijo-Garcia, Jonathan Gelfond, Andrew D. Meyer

“…Four patients in the tape group developed erythema and skin breakdown where the tube was secured with tape. …”
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Improving Explainability and Integrability of Medical AI to Promote Health Care Professional Acceptance and Use: Mixed Systematic Review by Yushu Liu, Chenxi Liu, Jianing Zheng, Chang Xu, Dan Wang

“…From the included studies, a conceptual framework was developed that delineates HCPs’ perceptions of explainability and integrability. …”
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Cognitive behavioural therapy in practice-nurse led behaviour-intervention for low back pain in German primary care – qualitative process evaluation of a feasibility study by Gregor Feldmeier, Stefan Zutz, Jennifer Höck, Anja Wollny, Peter Kropp, Attila Altiner, Christin Löffler

“…To address this gap, we have developed a nurse-led pragmatic group programme. This programme could be an approach for an additional treatment option for affected patients in a multiprofessional general practice. …”
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Engagement, Retention, and Progression to Type 2 Diabetes: A Retrospective Analysis of the Cluster-Randomised "Let's Prevent Diabetes" Trial. by Laura J Gray, Thomas Yates, Jacqui Troughton, Kamlesh Khunti, Melanie J Davies, Let’s Prevent Diabetes Team

“…Participants who were retained in the programme were also less likely to develop T2DM compared to those in the control arm (7 people of 130 versus 67 people of 433, HR 0.12 [95% CI 0.05-0.28]). …”
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Cognitive recovery of post critical care patients with and without COVID-19: differences and similarities, an observational study by Anna Gorsler, Christiana Franke, Anneke Quitschau, Nadine Külzow

“…Abstract Background Coronavirus disease (COVID-19) patients treated in an intensive care unit (ICU) are at high risk of developing cognitive impairments of a “post-intensive care syndrome” (PICS). …”
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Factors that influence uptake of routine postnatal care: Findings on women's perspectives from a qualitative evidence synthesis. by Emma Sacks, Kenneth Finlayson, Vanessa Brizuela, Nicola Crossland, Daniela Ziegler, Caroline Sauvé, Étienne V Langlois, Dena Javadi, Soo Downe, Mercedes Bonet

“…The analysis framework was developed a priori based on previous knowledge and research on the topic and adapted. …”
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Scoping review of employment resources for individuals with fetal alcohol spectrum disorder and justice involvement by James P Fitzpatrick, Carmela F Pestell, Marie M A Nankoo, Kirsten R Panton

“…Content analysis revealed common themes addressing FASD-related employment challenges and required supports.Conclusions This review highlights the need for developing evidence-based employment-related resources for justice-involved people with FASD. …”
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Feasibility of co-creating and delivering a youth-led noncommunicable diseases risk reduction intervention in schools of slums in Karachi, Pakistan: protocol for a mixed-methods, p... by Sabahat Naz, Munazzah Ilyas, Romaina Iqbal

“…However, there is limited literature from Pakistan that involves school-going adolescents in developing and delivering NCD risk-reduction interventions among their younger peers. …”
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The Hybrid Market Segmentation of Electric Vehicles in Ukraine Using Data Science Methods by Andrusyk Yevhenii V., Guryanova Lidiya S.

“…This market, on one hand, demonstrates exponential growth, while on the other, it develops in the context of significant economic and social challenges, which shapes a unique consumer behavior. …”
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Benefits and risks of health data reuse for healthcare providers: stakeholder perspectives from a qualitative interview study by Susanne Stark, Susanne Gabriele Schorr, Merle-Marie Pittelkow, Daniel Strech

“…Current ethical discussions on developing health data platforms (e.g. the German Medical Informatics Initiative, MII) have primarily addressed patient-related benefits and risks of reusing this data. …”
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Co-designing and evaluating a prenatal yoga intervention for ethnic minority women: a feasibility study by Carolina Estevao, Carola Chiarpenello, Winsze Kwok, Hemant Bhargav, Nishitha Jasti, Prabha Chandra, Shivarama Varambally, Carmine Pariante

“…This study primarily assessed the feasibility of a prenatal yoga module co-developed by King’s College London and the National Institute of Mental Health and Neurosciences (NIMHANS). …”
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Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol by Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Vivian Wing Yan Lee, Kai Chow Choi, Alexander Yuk Lun Lau, David R Thompson, Eddie Chi Fai Kwok

“…The intervention group will receive a newly developed 6-week novel custom-made SP-VR application comprising two sessions weekly. …”
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Validating a Patient-Reported Outcome Measure to Improve Emergency Department Asthma Care: Protocol for an Observational Study by Michelle P Lin, Lauren Gordon, Lynne D Richardson

“…We will use item response theory to develop scale responses based on summed item responses, which will allow us to test associations with clinical outcomes, including adherence to guideline-recommended care and return ED visits and hospitalizations. …”
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Pattern and Predictors of Maternal Healthcare Services Utilization among Women of Reproductive Age in Lagos, Nigeria by Esther Oluwakemi Oluwole, Alero Ann Roberts, Ifeoma Peace Okafor, Victoria Oluwasola Yesufu

“…Background: The world still grapples with alarming maternal mortality rates, particularly in developing nations, including Nigeria. Annual global deaths exceed 500,000, predominantly in developing countries (99%) and sub‑Saharan Africa (over 50%), where the lifetime risk of maternal death is 1 in 26. …”
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