Local Anesthesia Versus Saddle Block for Open Hemorrhoidectomy: Cost-Analysis From a Randomized, Double Blind Controlled Trial. by Sikakulya, Franck Katembo, Ssebuufu, Robinson, Okedi, Xaviour Francis, Baluku, Moris, Lule, Herman, Kiyaka, Sonye Magugu, Muhumuza, Joshua, Selamo, Fabrice Molen, Bassara, Godefroy Nyenke, Waziri, Musa Abbas, Kithinji, Stephen Mbae, Mugisho, Munyerenkana Leocadie, Byamungu, Pahari Kagenderezo, Munihire, Jeannot Baanitse, Vahwere, Bienfait Mumbere, Kiswezi, Ahmed, Kyamanywa, Patrick

“…Background Despite the benefits attributed to the use of local anesthesia (LA) for open hemorrhoidectomy (OH) in developed countries, this technique is still not considered as the first-line technique in low-income countries such as Uganda; therefore, we aimed to compare the cost of OH under LA versus Saddle block among patients with 3rd or 4th-degree hemorrhoids. …”
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Study Design and Rationale for the PHINDER Study: Pulmonary Hypertension Screening in Patients with Interstitial Lung Disease for Earlier Detection by Tejaswini Kulkarni, David A. Zisman, Oksana A. Shlobin, David G. Kiely, Maral DerSarkissian, Eric Shen, Kevin M. Maher, Meredith Broderick, Mary Beth Scholand

“…Trail Registration NCT05776225.…”
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Assessment of Oral Fluid HIV Test Performance in an HIV Pre-Exposure Prophylaxis Trial in Bangkok, Thailand. by Pravan Suntharasamai, Michael Martin, Kachit Choopanya, Suphak Vanichseni, Udomsak Sangkum, Pairote Tararut, Wanna Leelawiwat, Rapeepan Anekvorapong, Philip A Mock, Thitima Cherdtrakulkiat, Manoj Leethochawalit, Sithisat Chiamwongpaet, Roman J Gvetadze, Janet M McNicholl, Lynn A Paxton, Somyot Kittimunkong, Marcel E Curlin

“…Participants receiving tenofovir took longer to develop a reactive OraQuick (191.8 days) than participants receiving placebo (16.8 days) (p = 0.02) and participants infected with HIV CRF01_AE developed a reactive OraQuick earlier than participants infected with other subtypes (p = 0.04).…”
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Monitoring and enforcement of Code-based legal measures to protect breastfeeding in South Asia: opportunities and bottlenecks by Constance Ching, Vani Sethi, David Lawson Clark, Joo Kean Yeong, Katherine Shats, Zivai Murira, Ahmadwali Aminee, Dhammica Rowel, Golam Mohiuddin Khan, Khadheeja Ahmed, Kinley Dorji, Mazhar Iqbal, Muhammad Faisal, Phulgendra Prasad Singh, Saba Shuja

“…Overarching themes in opportunities include: (1) Product registration or licensing as entry points for monitoring and enforcement, (2) authority provided in legal measures for designated agencies to carry out monitoring and enforcement actions, (3) civil society as government partners in monitoring including developing monitoring tools and strengthening systems to integrate monitoring with enforcement. …”
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Pathology-Based Animal Cancer Registry of Abruzzo and Molise Regions (Central Italy): A Ten-Year Retrospective Study (2014–2023) by Giovanni Di Teodoro, Francesca Cito, Romolo Salini, Marina Baffoni, Sabrina V. P. Defourny, Antonio Cocco, Nicola D’Alterio, Chiara Palmieri, Antonio Petrini

“…The risk of developing skin and subcutaneous tissues tumors was higher for dogs and cats that lived mostly outdoor (PMR dogs = 1.21; 95% CI: 1.10–1.33; PMR cats = 1.18; 95% CI: 1.08–1.47), while dogs that live mainly indoor had a greater risk to develop mammary gland tumors (PMR = 0.78; 95% CI: 0.68–0.89). …”
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Neutrophil and neutrophil-lymphocyte ratios as predictors of clinical characteristics in patients with Lymphangioleiomyomatosis by Lulu Yang, Lulu Yang, Lulu Yang, Liting Huang, Liting Huang, Liting Huang, Yingquan Luo, Siying Ren, Siying Ren, Siying Ren

“…Differences between the two groups were compared, and significantly different indicators were further analyzed.ResultsA total of 78 patients with LAM were included in the study, 42 of them developed pneumothorax from registration to the end of follow-up, and 36 did not develop pneumothorax. …”
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Impact of depression and/or anxiety on patients with percutaneous coronary interventions after acute coronary syndrome: a protocol for a real-world prospective cohort study by Yan Liu, Zuyi Yuan, Jie Zheng, Juan Zhou, Xiang Hao, Manyun Guo, Wenyuan Li, Yihui Xiao, Xiaojie Cai, Zhanyi Zhang

“…Depression and/or anxiety after ACS is common. Studies from developed countries have reported that the occurrence of anxiety or depression after ACS might increase the risk of cardiovascular events and mortality. …”
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The impact of a heart failure management protocol based on a hospital-community pharmacist collaboration by Junichi Terashima, Takahiro Kambara, Eisei Hori, Masahiro Fukatsu, Yukina Ichiki, Eri Oki, Risako Koketsu, Rika Taguchi, Suzuka Mii, Ryoka Hiro, Teruhiro Sakaguchi, Hiroyuki Osanai, Tomoya Tachi, Tadashi Suzuki

“…Although there is growing interest in the management of heart failure by community pharmacists in Japan, no effective method has been developed. We created and verified the effectiveness of a novel heart failure management protocol that community pharmacists could utilize. …”
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Prevalence and risk factors of gross neurologic deficits in children after severe malaria: a systematic review protocol by Allen Eva Okullo, Chandy C. John, Richard Idro, Andrea L. Conroy, Alison Annet Kinengyere, Kevin Ouma Ojiambo, Caroline Otike, Simple Ouma, Moses Ocan, Ekwaro A. Obuku, Michael Boele van Hensbroek

“…Although CM patients are the most likely group to develop GND, it is not clear if other forms of severe malaria (non-CM) may also contribute to malaria-related GND. …”
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Antitumor proteinkinase inhibitor imatinib may be regarded as a potential correcting agent for COVID-19 associated pulmonary fibrosis by I. N. Mikhaylova, N. M. Treshalina, I. Zh. Shubina, I. V. Manina, M. V. Kiselevsky, A. N. Lukashev

“…As a result, hypoxia is developing, which is difficult to control and can cause lethal outcome in severe cases. …”
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11-Year Trend of Mortality from Fatal Road Traffic Injuries in The Center of Iran; a Cross-sectional Study by Maziyar Mollaei Pardeh, Mohammad Hosain Yarmohammadian, Golrokh Atighechian, Afshin Ebrahimi, Mohamad Reza Maracy

“… Introduction: Road traffic injuries (RTIs) are one of the major health problems in developed and developing countries. In Iran, RTIs are the first leading cause of years of life lost (YLL). …”
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Mental disorders and excess mortality: a systematic review protocol by Julie A Pasco, Michael Berk, Lana J Williams, Mohammadreza Mohebbi, Heli Koivumaa-Honkanen, Amanda L Stuart, Shae E. Quirk, Risto J Honkanen, Jeremi Heikkinen

“…Background There is developing evidence of excess mortality among people with mental disorders. …”
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Prediction of postoperative visual cognitive impairment using graph theory and machine learning based on resting-state brain networks by Songbin Liu, Zhaoshun Jiang, Pei Ye, Feidong Lv, Fei Tao, Yuxi Cai, Lina Yi, Shihong Li, Guoqing Wu, Jun Zhang, Weidong Gu

“…However, effective preoperative prediction methods remain lacking. We developed a machine learning model using graph theory analysis of resting-state functional connectivity networks to predict postoperative visual cognitive impairment. …”
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Validation of a delirium predictive model in patients admitted to surgical intensive care units: a multicentre prospective observational cohort study by Kaweesak Chittawatanarat, Onuma Chaiwat, Sirirat Mueankwan, Sunthiti Morakul, Pitchaya Dilokpattanamongkol, Chayanan Thanakiattiwibun, Arunotai Siriussawakul

“…This cut-off offered the highest value for Youden’s index (0.50), the best AUROC, and the optimum values for sensitivity (78.9%) and specificity (70.9%).Conclusions The model developed by the previous study was able to predict the occurrence of postoperative delirium in critically ill surgical patients admitted to SICUs.Trial registration number Thai Clinical Trail Registry (TCTR20180105001).…”
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Bringing together conceptualisations of the health advocacy competence across the continuum of medical education: a scoping review protocol by Dario Cecilio-Fernandes, Maarten F M Engel, Andrea M Woltman, Wilma R W Oosthoek, Lars T van Prooijen, Suzie J Otto

“…A comprehensive literature search was developed and already carried out in eight academic databases and Google Scholar, without restrictions on publication date, geography or language. …”
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Exploring the professional identity of physicians experienced in older persons’ health care - implications for medical education: A qualitative study by Annemarie Moll-Jongerius, Kirsten Langeveld, Wing Tong, Tahir Masud, Martin Smalbrugge, Anneke W.M. Kramer, Wilco P. Achterberg

“…Abstract Background Given the growing population of older persons, medical students need to develop an appropriate professional identity that enables them to give older persons the health care they need. …”
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Accuracy deficits during robotic time-constrained reaching are related to altered prefrontal cortex activity in children with cerebral palsy by Owais A. Khan, Tarkeshwar Singh, Deborah A. Barany, Christopher M. Modlesky

“…We hypothesized that reaching accuracy in children with CP would be lower than in typically developing children and would be related to PFC activity. …”
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A physical activity counseling intervention to promote health among pregnant women: a study protocol of randomized clinical trial by Xin Chen, Yong-fang Deng, Chun-feng Fu, Xiao Yang, Lingling Gao

“…Physical activity during pregnancy can lower the odds ratio of developing GDM and offer numerous health benefits for mothers and infants. …”
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Testing the effect of a dynamic descriptive social norm message on meat-free food selection in worksite cafeterias: a randomized controlled trial by Elif Naz Çoker, Rachel Pechey, Susan A. Jebb

“…The message was developed based on existing evidence and in collaboration with the catering company operating the cafeterias. …”
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Systematic review of the application of the Kidney Failure Risk Equation and Oxford classification in estimating prognosis in IgA Nephropathy by M. P. Toal, R. Fergie, M. P. Quinn, C. J. Hill, C. O’Neill, A. P. Maxwell

“…The kidney failure risk equation (KFRE) was developed to predict kidney failure in all causes of CKD and has been shown to be highly accurate across diverse etiologies. …”
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