Group cognitive stimulation therapy for people with intellectual disability and dementia: feasibility randomised controlled trial by Afia Ali, Cheryl Francis, Sarah Hoare, Joanna Carter, Nia Goulden, Caroline S. Clarke, Georgina Charlesworth, Zoe Hoare, Danny Acton, Shafia Khanum, Akinwande Onafalujo, Adebayo Jejeloye, Kate Brackley, Elisa Aguirre, Aimee Spector

Get full text

Epidemiological characteristics of suspected adenomyosis in the Chinese physical examination population: a nested case-control study by Wei Xu, Lijun Zhang, Qiuling Shi, Fan Xu, Ke Chen, Yanyan Huang, Ruoyan Gong, Yang Pu, Yuxian Nie, Xueyao Su, Jiayuan Zhang

“…The disease-specific threshold of CA125 will support further preventive strategy development in population.Trial registration number ChiCTR2100049520, 2021/8/2.…”
Get full text

A novel technique- subendometrial autologous platelet rich plasma injection in patients with unresponsive thin endometrium undergoing frozen-thawed embryo transfer: a prospective c... by Yigit Cakiroglu, Yusuf Aytac Tohma, Aysen Yuceturk, Ozge Karaosmanoglu, Ilke Ozer Aslan, Sule Yildirim Kopuk, Zeynep Ece Utkan Korun, Caglar Yazicioglu, Hulusi Bulent Zeyneloglu, Bulent Tiras

“…Conclusions In women with a history of suboptimal endometrial development, subendometrial PRP injection was associated with improved endometrial thickness and livebirth rate. …”
Get full text

Fatigue in patients with chronic obstructive pulmonary disease: protocol of the Dutch multicentre, longitudinal, observational FAntasTIGUE study by Mirjam A G Sprangers, Martijn A Spruit, Emiel F M Wouters, Daisy J A Janssen, Jean W M Muris, Judith B Prins, Yvonne M J Goërtz, Milou Looijmans, Melissa S Y Thong, Jeannette B Peters, Chris Burtin, Yvonne Meertens-Kerris, Arnold Coors, Jan H Vercoulen

Get full text

A Pilot Randomized Controlled Trial Assessing the Feasibility and Acceptability of Family-Partnered Delirium Prevention, Detection, and Management in Critically Ill Adults: The Act... by Kirsten M. Fiest, PhD, Karla D. Krewulak, PhD, Bonnie G. Sept, Judy E. Davidson, DNP, E. Wesley Ely, MD, Chel H. Lee, PhD, Andrea Soo, PhD, Henry T. Stelfox, MD

Get full text

Resistance training improves functional capacities in women with multiple sclerosis: a randomized control trial by Nasrin Niazi Nezhad, Abdolhossein Parnow, Kianoosh Khamoushian, Rasoul Eslami, Julien S. Baker

“…When we consider the clear role in MS pathogenesis and progression, antioxidant increases in relation to a reduction in pro-oxidant capacity would have provided a positive and important clinical development for people with MS.…”
Get full text

Time-dynamic associations between symptom-related expectations, self-management experiences and somatic symptom severity in everyday life: an ecological momentary assessment study... by Bernd Löwe, Yvonne Nestoriuc, Anne Toussaint, Stefanie Hahn, Franz Pauls, Simon Kirchhof

“…The effect of symptom-related expectations on subsequent symptom severity levels was independent of expectation framing.Conclusions Our findings highlight the impact of expectations and expectation framing on somatic symptom severity among university students and expand the knowledge needed for the development of expectation management techniques.Trial registration number ISRCTN36251388.…”
Get full text

Comparative Effectiveness of Phosphate Binders in Patients with Chronic Kidney Disease: A Systematic Review and Network Meta-Analysis. by Nigar Sekercioglu, Lehana Thabane, Juan Pablo Díaz Martínez, Gihad Nesrallah, Christopher J Longo, Jason W Busse, Noori Akhtar-Danesh, Arnav Agarwal, Reem Al-Khalifah, Alfonso Iorio, Gordon H Guyatt

“…We used the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach to rate the quality of evidence for each paired comparison.…”
Get full text

Patient-reported factors associated with emergency department referrals from a co-located out-of-hours walk-in clinic in Germany: a cross-sectional observational study by Martin Scherer, Ingmar Schäfer, Katharina Schmalstieg-Bahr, Johanna Sophie Bobardt-Hartshorn, Penelope-Sophie Peters, Bastian Bessert, Jan Hendrik Oltrogge-Abiry

“…These findings could support the development of triage tools for patients in OOH care.…”
Get full text

Analgesic efficacy and safety of erector spinae plane block versus serratus anterior plane block in breast surgery—a meta-analysis and systematic review of randomized controlled tr... by Samiullah Shaikh, Umm E Salma Shabbar Banatwala, Paranshi Desai, Muhammad Arham Khan, Rimsha Bint-e-Hina, Sidra Samad, Muhammad Hamza Sikandari, Ali Nawaz, Rana Ijaz, Shayan Asmat, Abeer Fatima, Harim Mirza, Noor Mahal Azam, Qurat Ul Ain Muhammad, Satesh Kumar, Mahima Khatri

“…The Cochrane Risk of Bias tool 2.0 (18) and Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) guidelines were used to appraise and evaluate the evidence (19). …”
Get full text

Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a. by Thomas C Darton, Claire Jones, Christoph J Blohmke, Claire S Waddington, Liqing Zhou, Anna Peters, Kathryn Haworth, Rebecca Sie, Christopher A Green, Catherine A Jeppesen, Maria Moore, Ben A V Thompson, Tessa John, Robert A Kingsley, Ly-Mee Yu, Merryn Voysey, Zoe Hindle, Stephen Lockhart, Marcelo B Sztein, Gordon Dougan, Brian Angus, Myron M Levine, Andrew J Pollard

“…While several licensed vaccines to prevent typhoid are available, they are of only moderate efficacy and unsuitable for use in children less than two years of age. Development of new efficacious vaccines is complicated by the human host-restriction of Salmonella enterica serovar Typhi (S. …”
Get full text

The Value of Remote Vital Signs Monitoring in Detecting Clinical Deterioration in Patients in Hospital at Home Programs or Postacute Medical Patients in the Community: Systematic R... by Su-Ann Cheng, Shijie Ian Tan, Samuel Li Earn Goh, Stephanie Q Ko

“…The GRADE (Grading Recommendations Assessment, Development, and Evaluation) framework was used to assess the certainty of evidence. …”
Get full text

Effectiveness of a school-based educational intervention on oral health knowledge, attitudes, practices, and self-efficacy among female secondary school students: a randomized cont... by Akram Mehtari Taheri, Fatemeh Zarei, Alireza Hidarnia, Mahmoud Tavousi

“…While genetics may have some influence, lifestyle factors such as diet, preventive care, and oral hygiene practices play a more critical role in the development of dental caries. The World Health Organization recognizes oral health as a lifelong cornerstone of overall well-being. …”
Get full text

Immersive Virtual Reality eHealth Intervention to Reduce Anxiety and Depression in Pregnant Women: Randomized Controlled Trial by Marta Jimenez-Barragan, Amparo Del Pino Gutierrez, Gloria Sauch Valmaña, Olga Monistrol, Carme Monge Marcet, Mar Pallarols Badia, Ignasi Garrido, Anna Carmona Ruiz, Oriol Porta Roda, Cristina Esquinas, Gemma Falguera Puig

“…Anxiety and depression affect up to 30% of pregnant women, with significant consequences for maternal well-being and child development. Despite this, interventions during pregnancy remain limited, creating a need for innovative, accessible solutions. …”
Get full text

The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study) by Taiji Hasegawa, Kenji Obayashi, Kimie Miyata, Tetsuo Ueda, Norio Kurumatani, Keigo Saeki, Nahoko Ogata, Hiroki Tsujinaka, Mariko Yamashita, Tomo Nishi, Nobuhiro Tone, Naonori Masuda, Yutarou Mizusawa, Masahiro Okamoto, Shinji Maruoka, Masashi Kojima, Toyoaki Matsuura

Get full text

Factors Influencing eHealth Literacy Worldwide: Systematic Review and Meta-Analysis by Zhong Hua, Song Yuqing, Liu Qianwen, Chen Hong

“…Meta-regressions were used to explore the effect of potential moderators, including participants’ characteristics, internet use measured by time or frequency, and country development status. Predictors of eHealth literacy were integrated according to the Literacy and Health Conceptual Framework and the Technology Acceptance Model (TAM). …”
Get full text

Administration of dehydroepiandrosterone improves endometrial thickness in women undergoing IVF/ICSI: a systematic review and meta-analysis by Ling Huang, Ying Gao, Shuo Liang, Mei Jiang

“…Risk of bias and quality of evidence (QoE) were assessed according to the Cochrane Collaboration’s tool and the Grading of Recommendations Assessment, Development and Evaluation system. Odds ratios (ORs) and mean differences (MDs) with 95% confidence intervals (CIs) were assessed by random-effects or fixed-effects models. …”
Get full text

Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials by Sumera Aziz Ali, Jeanine Genkinger, Ka Kahe, Linda Valeri, Nayab Khowaja, Nancy F. Krebs, Louise Kuhn

“…Systematic review registration PROSPERO CRD42023464966.…”
Get full text

Extended Reality Gaming for Exercise and Mindfulness Throughout Pediatric Cancer Rehabilitation: Protocol for a Randomized Controlled Trial by Byron Lai, Kelli Chaviano, Joshua S Richman, Mahmoud Ahmad, Ashley Wright, Raven Young, Drew Davis, James H Rimmer, Avi Madan-Swain, Joseph H Chewning

“…The knowledge obtained from this study will inform the development of a larger trial. Trial RegistrationClinicalTrials.gov NCT06298357; https://clinicaltrials.gov/study/NCT06298357 International Registered Report Identifier (IRRID)DERR1-10.2196/64879…”
Get full text

Digital Decision Aids to Support Decision-Making in Palliative and End-of-Life Dementia Care: Systematic Review and Meta-Analysis by Jie Zhong, Wei Liang, Tongyao Wang, Pui Hing Chau, Nathan Davies, Junqiang Zhao, Ho Nee Connie Chu, Chia Chin Lin

“…Articles were included if the study focused on the development and evaluation of a digital decision support tool on end-of-life dementia care, used an experimental design, and was available in full text in English. …”
Get full text