Protocol for a nested case-control study: identifying neuroimaging biomarkers for the progression of subclinical depression and qi-stagnation constitution to major depressive disor... by Jing Wang, Chengfeng Zhang, Yueqi Zhang, Yuanyuan Liu, Jingli Zhang, Xingwei Fang, Wangyang Xia, Yanzhao Xie, Zhongli Lan, Jinhui Wang, Jinhui Wang, Jinhui Wang, Jinhui Wang, Min Lu, Jun Chen, Jun Chen

“…Thus, early identification and intervention is crucial for adolescents at high risk for developing MDD. Subclinical depression (SD), characterized by depressive symptoms that do not meet the full criteria for MDD, substantially increases the risk of developing MDD. …”
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All-Russian Research Institute of Vegetable Breeding and Seed Production (VNIISSOK) is the oldest scientific institution; its leadership in Russian Agricultural Science by V.F. Pivovarov, L.K. Gurkina

“…The research core group of All-Russian Research Institute of Vegetable Breeding and Seed Production has developed over 700 cultivars and hybrids, 447 of them were included in the State Registration List of Achievements in Plant Breeding of Russian Federation in 2008.…”
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Associations between continuous glucose monitoring-derived metrics and diabetic retinopathy and albuminuria in patients with type 2 diabetes by Hirotaka Watada, Tomoya Mita, Takeshi Osonoi, Masahiko Gosho, Iichiro Shimomura, Toshihiko Shiraiwa, Yosuke Okada, Satomi Wakasugi, Naoto Katakami, Hidenori Yoshii, Keiko Nishida, Keiichi Torimoto, Akira Kurozumi

“…Introduction Preventing the development and progression of diabetic microvascular complications through optimal blood glucose control remains an important challenge. …”
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The median effective dose of oxycodone for acute postoperative pain after thoracoscopic pulmonary surgery with intercostal nerve blockin in patients of different ages: a dose-findi... by Min Zhang, Yi Liu, Jing Cao, Mengjie Liu, Xiaojun Gao, Na Guo, Chuansong Wei, Ye Zhu, Yongtao Sun, Jianbo Wu

“…Trial registration This study was registered on clinicaltrials.gov (NCT06534801) on August 1, 2024.…”
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Leading the way in pediatric sexual health screenings: evaluating pediatric emergency department workflows for the integration of STI screening tools by Laura Schubel, Deanna-Nicole Busog, Azade Tabaie, Monika Lemke, Danielle Foltz, Gia Badolato, Natasha Ajay Kaushal, Monika K. Goyal, Monika K. Goyal, Monika K. Goyal, Kristen Miller, Kristen Miller

“…Participants included patients, parents/caregivers, registration staff, nurses, social workers, child life specialists, providers, and health IT experts.ResultsThe primary study outcome was development of a general model of ED workflow and patient-clinician engagement, focusing on patient flow, clinical tasks, people, and technologies involved. …”
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Electromyography (EMG)-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation in persons with chronic stroke: a randomized, controlled trial by Mami Tani, Tomofumi Yamaguchi, Kaoru Honaga, Yoko Takahashi, Hidemi Kono, Yuhei Murakami, Reina Isayama, Koshiro Haruyama, Yuji Fujino, Tadamitsu Matsuda, Issei Fukunaga, Masaaki Hori, Akira Tanuma, Futoshi Wada, Kozo Hatori, Toshiyuki Fujiwara

“…Abstract Background Transcutaneous spinal stimulation has been applied to gait rehabilitation for persons with neurological diseases. The authors developed electromyography-triggered transcutaneous spinal cord and hip stimulation for gait rehabilitation and called this system FAST walk. …”
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Observational prospective study of social media, smartphone use and self-harm in a clinical sample of young people: study protocol by Rina Dutta, Kylee Trevillion, Ben Carter, Zohra Zenasni, Amanda Bye, Daniel Leightley, Maria Liakata, Stella Branthonne-Foster, Grace Williamson

“…The findings from this study will be disseminated through peer-reviewed scientific journals, conferences, websites, social media and stakeholder engagement activities.Trial registration number NCT04601220.…”
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Unravelling neutropenic enterocolitis: insights from gut microbiota, and intestinal barrier analyses by Natacha Kapandji, Maud Salmona, Anaïs Lemoine, Guillaume Ulmann, Julien Calderaro, Brigitte Roche, Nathalie Kapel, Lucie Biard, Etienne Lengline, Jérôme Le Goff, Christophe Rodriguez, Muriel Thomas, Lara Zafrani

“…Severe NE is marked by the development of a local inflammatory response that may be induced by the reduction in butyrate levels. …”
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A hybrid convolutional neural network model for dental age estimation using buccal alveolar bone level for Saudi children by Seyed Matin Mazloom Nezhad, Erma Rahayu Mohd Faizal Abdullah, Norliza Ibrahim, Heba H. Bakhsh, Uzair Ishtiaq, Rabiah Al Adawiyah Rahmat, Sarah AlMugairin, Sara M. ElKhateeb

“…Teeth are commonly used for age estimation because the schedules of tooth development and eruption are barely affected by the environment, nutrition, and socio-economic factors. …”
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Barriers and facilitators associated with steps of the HIV care cascade for migrants in OECD countries: a systematic mixed studies review protocol by Bertrand Lebouché, Isabelle Vedel, Anish Arora, Amelie Quesnel-Vallee, David Lessard, Kedar Mate, Adriana Rodriguez-Cruz, Nadine Kronfli, Kim Engler

“…Introduction In 2019, the United Nations signalled a substantial rise in the number of international migrants, up to 272 million globally, about half of which move to only 10 countries, including 8 member nations of the Organization for Economic Co-operation and Development (OECD). Migrants in OECD countries are often at higher risk for acquiring HIV and have a higher frequency of delayed HIV diagnosis. …”
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Incidence of cancer-related lymphoedema: a protocol for a living systematic review with meta-analysis by Nele Devoogdt, Hildegard Reul-Hirche, Kira Bloomquist, Michael Bernas, Ben Singh, Sandi Hayes, Melanie Plinsinga, Debbie Geyer, Louise Koelmeyer, Neil Piller, Stanley Rockson

“…The overall strength of evidence will be appraised with the Grading of Recommendations, Assessment, Development and Evaluations tool. Random effect models will be used to produce pooled overall lymphoedema incidence estimates. …”
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mHealth Incentivized Adherence Plus Patient Navigation (MIAPP): protocol for a pilot randomized controlled trial to improve linkage and retention on buprenorphine for hospitalized... by Elenore P. Bhatraju, Devin N. Kennedy, Alexander J. Gojic, Matthew Iles-Shih, Joseph O. Merrill, Jeffrey H. Samet, Kevin A. Hallgren, Judith I. Tsui

“…Methods The study is a two-arm pilot randomized controlled trial (N = 40) comparing the mHealth Incentivized Adherence Plus Patient Navigation (MIAPP) intervention to treatment as usual. Development of the MIAPP intervention was guided by the information-motivation-behavioral skills model and combines financial rewards via mobile health-based adherence monitoring with the “human touch” of a patient navigator. …”
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Serplulimab combined with gemcitabine, nab-paclitaxel and stereotactic body radiotherapy as the first-line treatment for patients with metastatic pancreatic adenocarcinoma in China... by Dan Cao, Ke Cheng, Chenyan Zhang, Deying Kang, Ruizhen Li, Chen Chang, Heqi Yang, Junjie Xiong, Du He, Xi-Jiao Liu

“…Introduction Patients with pancreatic ductal adenocarcinoma (PDAC) remain a poor prognosis despite the development of chemotherapy. Although programmed cell death 1 (PD-1) blockade has shown great efficacy in various solid tumours, its application in treating PDAC is limited. …”
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Lack of effect of Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12 on beta-cell function in children with newly diagnosed type 1 diabetes: a randomised controlled trial by Hania Szajewska, Agnieszka Szypowska, Lidia Groele, Mieczysław Szalecki, Jolanta Świderska, Marta Wysocka-Mincewicz, Agnieszka Ochocińska, Anna Stelmaszczyk-Emmel, Urszula Demkow

“…Introduction The gut microbiota may be relevant in the development of type 1 diabetes (T1D). We examined the effects of Lactobacillus rhamnosus GG and Bifidobacterium lactis Bb12 on beta-cell function in children with newly diagnosed T1D.Research design and methods Children aged 8–17 years with newly (within 60 days) diagnosed T1D were enrolled in a double-blind, randomised controlled trial in which they received L. rhamnosus GG and B. lactis Bb12 at a dose of 109 colony-forming units or placebo, orally, once daily, for 6 months. …”
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Mapping the interactions of critical factors in China’s first-contact healthcare systems using causal loop diagrams by Wenjun He, Yusupujiang Tuersun, Tao Yang, Yuting Wan, Minji Yong, Zizhen Huang, Zhiyong Xiao, Menglin Luo, Yujia Zhang, Yujie Liu, Tao Yang, Yi Qian, Dong Roman Xu

“…Using Causal Loop Diagram (CLD) methodology, this study mapped the causal pathways and feedback mechanisms among factors such as health insurance awareness, medical consortium development, and tiered healthcare policy guidance. …”
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Structural brain changes in hyperthyroid Graves’ disease: protocol for an ongoing longitudinal, case-controlled study in Göteborg, Sweden—the CogThy project by Rolf A Heckemann, Mats Olof Holmberg, Helge Malmgren, Peter Berglund, Lina Bunketorp-Käll, Birgitta Johansson, Niklas Klasson, Erik Olsson, Simon Skau, Helena Nystrom Filipsson

“…The results will be actively disseminated through peer-reviewed journals, national and international conference presentations and among patient organisations after an appropriate embargo time.Trial registration number 44321 at the public project database for research and development in Västra Götaland County, Sweden (https://www.researchweb.org/is/vgr/project/44321).…”
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Feasibility and implementation of a healthy lifestyles program in a community setting in Ontario, Canada: protocol for a pragmatic mixed methods pilot study by Zainab Samaan, David Feeny, Lawrence Mbuagbaw, Elizabeth Alvarez, Majdi Qutob, John Lavis, Cynthia Lokker, Marjan Walli-Attaei, Arielle Sutton, Japteg Singh, John Fortuna

“…Mental health and other determinants of health play a role in the development and progression of chronic conditions. Changing habits takes time and requires the use of multiple techniques, including mental health and behavioural change strategies, based on a person’s needs. …”
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A semi-automatic pipeline integrating histological and µCT data in a mouse model of lung fibrosis by Elena Vincenzi, Martina Buccardi, Erica Ferrini, Alice Fantazzini, Eugenia Polverini, Gino Villetti, Nicola Sverzellati, Andrea Aliverti, Curzio Basso, Francesca Pennati, Franco Fabio Stellari

“…By facilitating a detailed and objective view of disease progression and treatment response, this approach has the potential to accelerate the development of effective therapies for lung fibrosis.…”
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Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional diso... by Yanli Zhao, Jiahua Xu, Jie Zhang, Jiaqi Song, Ning Yang, Hongzhen Fan, Zhe Dong, Shuping Tan

“…Trial registration ChiCTR2100044553, Registered March 24, 2021.…”
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Knowledge on melioidosis among healthcare workers of Bangladesh by Sraboni Mazumder, Tabiha Binte Hannan, Fahmida Rahman, Saika Farook, Forhad Uddin Hasan Chowdhury, Lovely Barai, Chandan Kumar Roy, Kutub Uddin Ahamed, Md. Shariful Alam Jilani, Fazle Rabbi Chowdhury

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