Pragmatic, multicentre, randomised controlled trial of a Hospital-Community-Home Tiered Transitional Care (HCH-TTC) programme for individuals with type 2 diabetes: a study protocol by Hongyan Wang, Min Lu, Zheng Zhu, Ruijie Ma, Baiyun Zhou, Mengyao Shao, Yanmei Wang

“…Introduction Type 2 Diabetes Mellitus (T2DM) and its complications significantly increase the risk of premature mortality and disability among patients, placing a considerable burden on socioeconomic development. Evidence has shows that effective transitional care can improve health outcomes for patients with T2DM. …”
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Predictability of kinetic estimated glomerular filtration rate for acute kidney injury in patients undergoing coronary artery bypass surgery by Mohammad Ali Haghighatpanah, Sadegh Mazaheri-Tehrani, Amirhosein Adibzadeh, Negar Ostadsharif, Parham Moradi, Mahshad Vali, Roya Riahi, Mohsen Mirmohammadsadeghi

“…We found that patients with higher values of neutrophil-lymphocyte-platelet ratio (NLPR) had an increased risk of developing AKI compared to those with lower values (OR: 1.74; 95%CI: 1.07 to 2.83). …”
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Patient safety in the ‘Room of Horrors’ simulation: a multi-method study of student, novice, and experienced nurses by Seung Eun Lee, Hyun Joo Lee, V. Susan Dahinten, Won Jin Seo, Heejin Lim, Hanjoe Kim

“…The Room of Horrors (ROH) simulation was developed to enhance these skills by presenting learners with a simulated patient scenario containing safety hazards. …”
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Updating methodological and source database of binominal denominations of introduced cultivars with elements of extrapolation by Н. В. Лещук, Н. П. Костенко, Н. В. Павлюк, В. А. Павлюк

“…It is the binary nomenclature of introduced cultivars that requires a scientific approach to structuring and developing the methodological and source learning database of botanical names in Ukrainian and Latin. …”
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Conveying Cappadocia. A new representation model for rock-cave architecture by contour lines and chromatic codes by Fabio Colonnese, Marco Carpiceci, Carlo Inglese

“…In the context of a work methodology customized on the rupestrian habitat of Cappadocia (Turkey), the authors developed an original envisioning model in which an associate use of contour lines and chromatic codes transforms traditional orthogonal projections after the numeric model into drawings able to offer a synthesis and transmit the complex forms and relationships of rupestrian settlements.…”
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Smart Contract Blockchain for Supporting Therapy of Neurological Patients by U. А. Vishniakou, Yu Chuyue

“…The functional structure of the therapy support subsystem (smart contract in the Etherium blockchain) has been developed, including initialization of patient data, treatment plans, registration of medical staff, record management, dynamic switching of therapy plans based on diagnostic data, monitoring of medical staff warnings, as well as management of payments and their distribution. …”
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Transforming Non-Digital, Clinical Workflows to Detect and Track Vision-Threatening Diabetic Retinopathy via a Digital Platform Integrating Artificial Intelligence: Implementation... by Peranut Chotcomwongse, Paisan Ruamviboonsuk, Chaiwat Karavapitayakul, Koblarp Thongthong, Anyarak Amornpetchsathaporn, Methaphon Chainakul, Malee Triprachanath, Eckachai Lerdpanyawattananukul, Niracha Arjkongharn, Varis Ruamviboonsuk, Nattaporn Vongsa, Pawin Pakaymaskul, Turean Waiwaree, Hathaiphan Ruampunpong, Richa Tiwari, Viroj Tangcharoensathien

“…To integrate the screening programs, with or without artificial intelligence (AI), into hospital information systems to improve their effectiveness, the non-digital workflow must be transformed into digital. We developed a cloud-based digital platform and implemented it in an existing DR screening program. …”
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Digital therapeutics approach for young children with myopia using SAT-001 (DAYS): study protocol for a randomized controlled trial by Hae Jung Paik, Byung Joo Lee, Dong Hui Lim, So Young Han, Eun Hye Jung, Hyun Jin Shin, Hyun Kyung Kim, Ungsoo Samuel Kim, Won Jae Kim, Hee Young Choi, Jihae Park, Soolienah Rhiu, Jihye Lee, Moonjeong Kim, Kyunghee Kim

“…SAT-001 is a novel digital therapeutic software developed for myopia control and is designed to overcome the limitations of existing therapies. …”
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Using the Ethereum Blockchain in the Internet of Things Network for IT Diagnostics by U. A. Vishniakou, YiWei Xia, Chuyue Yu

“…An integrated system architecture has been developed that combines the IoT network, the IPFS (InterPlanetary File System) file structure with the Ethereum blockchain to create a reliable data storage model. …”
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The state of the cardiovascular system in typhoid fever (Experience of a leading infectious disease specialist of a limited contingent of Soviet troops in Afghanistan) by Yu. I. Ljashenko

“…It has been established that patients with an extremely severe form of relapse of typhoid in connective tissue develop in the intercardiomyocytic intervals.…”
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Analyse de traces d’interaction et reconceptualisation des indicateurs de performance de MOOC : une revue de littérature by Matthieu Cisel

“…The use of the certification rate reduces the weight of the non-certified, who can develop a significant activity, invisible by the choice of certain indicators, as shown by trace analyzes and interviews with learners. …”
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Safety, immunogenicity, efficacy, and effectiveness of Lassa fever vaccines in pregnant persons, children, and adolescents: a protocol for a living systematic review and meta-analy... by Jamile Ballivian, Mabel Berrueta, Agustín Ciapponi, Juan Manuel Sambade, Katharina Stegelmann, Agustina Mazzoni, Ariel Bardach, Martin Brizuela, Daniel Comandé, Noelia Castellana, Edward P. K. Parker, Andy Stergachis, Xu Xiong, Flor M. Munoz, Pierre M. Buekens

“…While several vaccine candidates have been developed, none have received regulatory approval. …”
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Key Points for Quality Management in Phase Ⅰ Clinical Trials of Anti-Tumor Drugs by Li GONG, Bin LIAO, Jie SHEN, Juan ZHAO, Yi GONG, Xiaoxiao LU, Huiyao YANG, Sha LI, Yongsheng LI

“…Phase Ⅰ clinical trials play a crucial role in the research and development of new drugs, serving as the initial studies to assess their safety, tolerability, effectiveness, and pharmacokinetic properties in humans. …”
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Evaluation of a transdiagnostic mental health intervention in German primary care: study protocol for a parallel-group, two-arm, cluster randomised controlled pilot study by Christopher Ebert, Marie Vogel, Jochen Gensichen, Hanna Reif, Lena Grögor, Lukas Junker, Thomas Ehring, Alkomiet Hasan, Stefan Leucht, Kirsten Lochbühler, for the POKAL-Group

“…Thus, a transdiagnostic intervention adapted from the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders was developed specifically for primary care. In a parallel-group, two-arm, cluster randomised controlled pilot study, the transdiagnostic intervention will be evaluated for feasibility, acceptability and potential effectiveness in German primary care. …”
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Effect of intravenous versus inhaled anesthetics on blood-brain barrier dysfunction and neuroinflammation in elderly patients undergoing major surgery: study protocol of a randomiz... by Wongook Wi, Hyo-Jin Kim, Sira Bang, Oh Joo Kweon, Doyeon Kim, Eun Jung Oh

“…Also, the study results will provide additional information to develop intraoperative anesthetic strategies to reduce POCD. …”
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The HOME (home monitoring of high-risk pregnancies) study: a study protocol for an observational study of a telemedicine-assisted follow-up at home vs. hospitalization by Åsa Henning Waldum, Aase Serine Devold Pay, Aase Serine Devold Pay, Gunvor Aasbø, Vinod Kumar Mishra, Meryam Sugulle, Meryam Sugulle, Anne Cathrine Staff, Anne Cathrine Staff

“…BackgroundPregnancies at high risk for adverse health outcomes for mother and offspring often require long-term antenatal hospitalization and/or frequent outpatient visits. We have developed a telemonitoring home care service for high-risk pregnancies that has been integrated into the Electronic Patient Journal System of our department. …”
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General practitioners’ scanning competence following tailored ultrasound training: a hybrid effectiveness-implementation study by Camilla Aakjær Andersen, Søren Lundbye-Christensen, Allan Riis, Ulrike Mehnert, Thomas Løkkegaard, Troels Mengel-Jørgensen, Liv Dyre Rasmussen, Nicolai Soll, Bo Stork, Søren Kæseler Andersen, Louise Pil, Christian Stjernebjerg, Ole Graumann, Martin Bach Jensen

“…Conclusion This study emphasizes that a customized training program, considering the learning challenges faced by office-based GPs, can result in scanning proficiency that continues to develop in the months following the training. Trial registration Clinical trials registration ID NCT05274581.…”
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Community intervention to reduce cardiovascular disease in Chicago (CIRCL-Chicago): protocol for a type 3 hybrid effectiveness-implementation study using a parallel cluster-randomi... by Justin D. Smith, Allison J. Carroll, Yacob G. Tedla, Olutobi A. Sanuade, James L. Merle, Jennifer Heinrich, Jenn Bannon, Emily M. Abramsohn, Faraz S. Ahmad, Danielle Lazar, Stacy Tessler Lindau, Megan C. McHugh, Rasha Khatib, Ramona Donovan, Elizabeth A. Pinkerton, Linda L. Rosul, Theresa L. Walunas, Ricky Watson, Tejashri Ganbote, Namratha Kandula, Quentin R. Youmans, Paris Davis, Abel N. Kho

“…A key partner for this trial, the Total Resource Community Development Organization, isa faith-based community outreach hub networked with faith-based organizations throughout Chicago’s South Side community. …”
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Transforming healthcare by prioritizing qualitative and quantitative clinical trial evidence: evaluating the Aging, Community and Health Research Unit’s Community Partnership Progr... by Kathryn Fisher, Soo Chan Carusone, Rebecca Ganann, Maureen Markle-Reid, Melissa Northwood, Diana Sherifali

“…To synthesize the findings and guide integration of this large body of evidence, we developed a conceptual model which combined two existing frameworks: the Consolidated Framework for Implementation Research and Quintuple Aim. …”
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The socioecological model levels, behavior change mechanisms, and behavior change techniques to improve accelerometer-measured physical activity among Hispanic women: a systematic... by Elizabeth Lorenzo, Jeni Page, Rebeca Wong, Elizabeth Lyons

“…Conclusions Interventions to increase Hispanic women’s accelerometer-measured MVPA in the shorter-term should be developed to include BCT to increase self-efficacy (intrapersonal level) and family participation (interpersonal level) and identify physical activity opportunities/access (neighborhood level), including BCT to overcome safety and weather barriers. …”
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