Vestibular Infant Screening-Rehabilitation (VIS-REHAB): protocol for a randomised controlled trial on Vestibular Rehabilitation Therapy (VRT) in vestibular-impaired children by Ruth Van Hecke, Leen Maes, Ingeborg Dhooge, Marieke Fontaine, Cleo Dhondt, Frederic Acke, Lena Van den Bossche, Helen Van Hoecke, Els De Leenheer

“…Introduction A vestibular deficit can have a substantial impact on the overall development of children. Therefore, it is of utmost importance that vestibular-impaired problems are treated early and effectively through Vestibular Rehabilitation Therapy (VRT). …”
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Digital Therapeutics in China: Comprehensive Review by Nan Jiang, Xiru Yu, Yuxi Yang, Guanqiao Li, Chanchan He, Man Ping Wang, Yih Chung Tham, Tien Yin Wong, Keqin Rao

“…The findings provide insights for countries aiming to develop, regulate, and integrate DTx solutions into health care systems. …”
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FitSkills: protocol for a stepped wedge cluster randomised trial of a community-based exercise programme to increase participation among young people with disability by Nicholas F Taylor, Nora Shields, Andrea M Bruder, Claire Willis, Christine Imms, Luke A Prendergast, Jennifer J Watts, Ben van Dorsselaer, Georgia McKenzie, Luke Prendergast, Jason Calleja, David Strickland, Shawn Stephenson, Michael P Walker, Justine Robbins, Melissa Barkley, Cameron Geddes, Shane Lee, Richard Amon, Juliet Ryan, Ayden Shaw, Simone Power, Rebecca McCabe, Shannon Cheal, Vicki Cavelieros, Debby Fraumano, Sue Blandford, Lucy Bain, Sonia Bonadio, Sue O’Riley, Bernadette Roberts, John Summers, Troy Walker, Fiona Kriaris, Sam Taylor, Tom Scanlan, Abigail Elliot, Lachlan O’Brien, Jenni Smith, Stacey Cleary, Brooke Adair, Melissa Moore, Jess Kuek

“…Introduction There is a need to develop relevant, acceptable initiatives that facilitate physical activity participation in young people with disability. …”
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Laying the foundation for an International Classification of Functioning, Disability and Health Core Set for community-dwelling elderly adults in primary care: the clinical perspec... by Thomas Kuehlein, Johanna Tomandl, Stephanie Book, Gudrun Ulbrecht, Susann Gotthardt, Ellen Freiberger, Elmar Graessel

“…Along with lists from the other three preparatory studies, it will form the basis for the development of an ICF Core Set for community-dwelling older adults in primary care.Trial registration details The trial is registered in ClinicalTrials.gov (NCT03384732).…”
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What items should be included in an early warning score for remote assessment of suspected COVID-19? qualitative and Delphi study by David Nunan, Simon de Lusignan, Ana Luísa Neves, Laiba Husain, Brendan Delaney, Paul Thompson, Sietse Weiringa, Merlin Dunlop, Alexander Rushforth

“…Background To develop items for an early warning score (RECAP: REmote COVID-19 Assessment in Primary Care) for patients with suspected COVID-19 who need escalation to next level of care.Methods The study was based in UK primary healthcare. …”
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Predictive machine learning algorithm for COPD exacerbations using a digital inhaler with integrated sensors by Michael Reich, Njira Lugogo, Laurie D Snyder, Megan L Neely, Guilherme Safioti, Randall Brown, Michael DePietro, Roy Pleasants, Thomas Li, Lena Granovsky

“…Features of the model with the highest weight were baseline inhalation parameters and changes in inhalation parameters before an exacerbation compared with baseline.Conclusion We demonstrated the development of a proof-of-concept machine learning model predictive of impending COPD exacerbations using data from the integrated digital reliever inhaler. …”
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Optimising neonatal service provision for preterm babies born between 27 and 31 weeks gestation in England (OPTI-PREM), using national data, qualitative research and economic analy... by Neena Modi, Elizabeth S Draper, Miaoqing Yang, Sarah E Seaton, Oliver Rivero-Arias, Thillagavathie Pillay, Brad Manktelow, Natalie Armstrong, Alexis Paton, Abdul Qader Tahir Ismail, Elaine M Boyle

“…Dissemination will be through publication of findings and development of recommendations for care.Trial registration number NCT02994849 and ISRCTN74230187.…”
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The effects of an immersive virtual reality and telemedicine-based multi-component intervention in individuals with subjective cognitive decline: study protocol of a randomized con... by Maria Stefania De Simone, Maria Stefania De Simone, Silvia Zabberoni, Silvia Zabberoni, Alberto Costa, Alberto Costa, Erika Tenaglia, Erika Tenaglia, Gaetano Tieri

“…BackgroundOlder adults with subjective cognitive decline (SCD) are at high risk of developing dementia and frequently experience subclinical symptoms (e.g., anxiety, depression) which are themselves associated with an increased dementia and cognitive decline risk. …”
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Risk prediction models for ovarian hyperstimulation syndrome: a systematic review and meta-analysis by Jinghui Liu, Fangli Liu, Wenqi Xu, Luwen Zhang, Qingmi Tian, Libaihe Du, Siyuan Li, Mingyang Zhang

“…Trial registration: PROSPERO CRD420251025876.…”
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A scoping review of outcome selection and accuracy of conclusions in complex digital health interventions for young people (2017–2023): methodological proposals for population heal... by Claire Collin, Clara Eyraud, Philippe Martin, Morgane Michel, Enora Le Roux, Corinne Alberti

“…PROSPERO Registration number CRD42023401979.…”
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Association between child and youth physical activity and family functioning: a systematic review of observational studies by Yasmine Forghani Soong, Heather Hollman, Ryan E. Rhodes

“…In particular, active families support well developed and resilient offspring. As the family unit is optimally placed during a critical time in development, it is pertinent to explore the relationship between family functioning and child and youth physical activity. …”
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Slope Protection Structures at Water Reservoirs in Belarus and Causes of their Deformations by V. E. Levkevich

“…The results of on-site and laboratory investigations on protection stability have permitted to determine that the following reasons influence on the development of deformations: presence of objective inaccuracies and assumptions in the accepted calculated design schemes and dependencies for determination of protection parameters; lack of completeness in registration of conditions for wave formation and level regime of reservoirs; initial data and survey materials do not always provide true information about ground conditions for construction of bank protection facility; technological deviations while constructing structures and their protection. …”
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Impact of family-oriented gamification on self-management of people with multiple sclerosis: a mixed-methods study protocol by Arezoo Rasti, Leily Zare, Nahid Dehghan nayeri, Fatemeh Bahramnezhad

“…Next, web-based and card gamification will be developed for patients and their families based on the findings of the qualitative phase. …”
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Healthcare professionals’ and patients’ views and experiences of surgical and medical treatment for nasal obstruction: a qualitative interview study for a Nasal Airway Obstruction... by Leila Rooshenas, David Hamilton, Nikki Rousseau, Emma Clark, Janet A Wilson, Caroline Wilson, Sean Carrie, Kelly E Lloyd

“…For patients, better information about treatment mechanisms, treatment delivery and aftercare, and the development of decision support tools would enable shared decision-making and help to provide optimal patient experience of the treatments.Trial registration number ISRCTN16168569.…”
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Assessment of the quality and content of clinical practice guidelines for vitamin D and for immigrants using the AGREE II instrument: global systematic review by George A Wells, Ian Colman, Lamia Hayawi, Nazmun Nahar, Doug Manuel, Said Yousef, Alomgir Hossain, Emmanuel Papadimitropoulos, MoezAlIslam E Faris, Leenah Abdelrazeq

“…Urgent national and international efforts are needed to develop comprehensive CPGs, bridging research, policy and practice disparities. …”
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Non-randomised prospective clinical trial to improve follow-up adherence, survivorship knowledge and late effects documentation at a childhood cancer clinic in Western Kenya: a stu... by Festus Njuguna, Gertjan Kaspers, Gilbert Olbara, Terry Vik, Jesse Lemmen, Susan Mageto

“…Findings will also be shared with governmental and non-governmental organisations that support children with cancer in Kenya to inform their target audiences and guide their policy development.Lessons learnt from this study could inform healthcare providers and policy makers on how to shape survivorship programmes in the Kenyan context and possibly implement similar programmes in other centres in Sub-Saharan Africa.Trial registration number NCT06680687.…”
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Impact of ambient heat exposure on pregnancy outcomes in low- and middle-income countries: A systematic review by Sohail Lakhani, Sobia Ambreen, Zahra Ali Padhani, Yusra Fahim, Sana Qamar, Salima Meherali, Zohra S Lassi

“…Pregnant women and their fetuses are among the most vulnerable groups being affected by these dramatic changes resulting in adverse outcomes for both the mother and the developing fetus. Evidence regarding heat-related pregnancy adversities in high-income countries is conclusive, however, such evidence is rare in low- and middle-income countries (LMICs). …”
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Identification of Compounds With Potential Dual Inhibitory Activity Against Drug Efflux Pumps in Resistant Cancer Cells and Bacteria: Protocol for a Systematic Review by Elina Beleva, Antonia Diukendjieva, Ilza Pajeva, Ivanka Tsakovska

“… BackgroundDrug efflux mediated by transporter proteins is one of the major mechanisms conferring multidrug resistance (MDR) to antimicrobial agents in bacteria and to chemotherapeutics in cancer cells. Therefore, the development or identification of efflux modulators represents a promising strategy to overcome the resistant phenotype. …”
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“It’s like going through life at a mediocre level”: a qualitative study of the meaning and impact of fatigue in children and young people with sickle cell disease by Brenda Agyeiwaa Poku, Karl Michael Atkin, John David Grainger, Iyamide Thomas, Rachael Oshinbolu, Abubakar Mohammed, Edith Kyewalyanga, Susan Kirk

“…The findings emphasise recognising fatigue as a primary symptom in CYP with LTCs, given its severe impact on social and educational development and future stability. Trial registration Not Applicable.…”
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Generation Healthy Kids: Protocol for a cluster-randomized controlled trial of a multi-component and multi-setting intervention to promote healthy weight and wellbeing in 6-11-year... by Louise T Thomsen, Jesper Schmidt-Persson, Camilla Trab Damsgaard, Peter Krustrup, Anders Grøntved, Rikke Fredenslund Krølner, Glen Nielsen, Jesper Lundbye-Jensen, Thomas Skovgaard, Christian Mølgaard, Anders Blædel Gottlieb Hansen, Didde Hoeeg, Malte Nejst Larsen, Line Lund, Paulina Sander Melby, Natascha Holbæk Pedersen, Jens Troelsen, Nikolai Baastrup Nordsborg, Ulla Toft

“…"Generation Healthy Kids" (GHK) is a multi-setting, multi-component intervention to promote healthy weight development, health and wellbeing in Danish children aged 6-11 years. …”
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