VR READY: a protocol for a non-randomised, single-arm, mixed methods, feasibility trial of a coproduced ViRtual REality intervention to AiD recoverY in people recently admitted to... by Ceri Battle, Michelle Smalley, Kim Smallman, Paul Twose, Katherine Cullen, Ceri Lynch, Sarah Gill, Alys Irving, Cheney J G Drew, Craig Greenstock, Domonic White

“…It has been suggested that the use of digital tools such as virtual reality (VR) may play a useful role in the development of recovery-supporting interventions. We engaged with people with lived experience of critical care admission to coproduce a VR intervention (ViRtual REality to AiD recoverY post ICU (VR READY)). …”
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Protocol for the economic evaluation of individualised (early) patient-directed rehabilitation versus standard rehabilitation after surgical repair of the rotator cuff of the shoul... by Chris Littlewood, Marcus Bateman, Vijay S Gc, Andrea Manca, T Chen, Bruno Mazuquin, Apostolos Fakis, Maria Moffatt, Shainur Premji

“…Findings will be disseminated in peer-reviewed journals, at scientific conferences, and via the study website.Trial registration number ISRCTN11499185…”
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Black raspberry supplementation on overweight and Helicobacter pylori infected mild dementia patients a pilot study by Yohanes Tandoro, Hui-Fang Chiu, Chei-Ling Tan, Ming-Hong Hsieh, Yi-Wen Huang, Jianhua Yu, Li-Shu Wang, Chi-Ho Chan, Chin-Kun Wang

“…This study aimed to determine whether supplementation of BRBs has a meaningful effect on H. pylori infection, overweight, and AD development in a clinical trial setting. We conducted a randomized placebo-controlled clinical trial in patients with mild clinical dementia who also had H. pylori infection and were overweight. …”
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Pharmacokinetics and Safety Profile of SNS812, a First in Human Fully Modified siRNA Targeting Wide‐Spectrum SARS‐CoV‐2, in Healthy Subjects by Yi‐Chung Chang, Yi‐Fen Chen, Chi‐Fan Yang, Hui‐Ju Ho, Jen Fu Yang, Yuan‐Lin Chou, Ching‐Wen Lin, Pan‐Chyr Yang

“…ABSTRACT Severe acute respiratory syndrome caused by the coronavirus (SARS‐CoV‐2) in the COVID‐19 pandemic has highlighted the need for effective treatments, as rapid viral mutations complicate therapeutic development. SNS812, a fully modified inhaled siRNA that targets the conserved RNA‐dependent RNA polymerase (RdRP) gene of SARS‐CoV‐2, has been shown to possess its suppression ability against wide‐spectrum SARS‐COV‐2 variants preclinically. …”
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Effects of cupping therapy on chronic musculoskeletal pain and collateral problems: a systematic review and meta-analysis by Tingting Sun, Yuanyuan Jia, Xiaosheng Dong, Yunlong Chai, Zhenmin Bai, Xiao Hou

“…But it cannot improve functional disability and mental health significantly.PROSPERO registration number CRD42023406219.…”
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Efficacy and safety of HYYK formula for residual follicle revival in premature ovarian insufficiency: a multicenter, randomized, double-blind, placebo-controlled trial protocol by Yin Peng, Jian Liu, Yang Li, Guangning Nie, Fangping Cheng, Daning Feng, Qiaolin Du, Jian Huang, Hongyan Yang

“…This study will concentrate on stimulating residual follicle development in POI patients, offering a viable approach to delaying ovarian decline and generating compelling clinical evidence. …”
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Exploring the effectiveness of technology-based learning on the educational outcomes of undergraduate healthcare students: an overview of systematic reviews protocol by Muhammad Hibatullah Romli, Manraj Singh Cheema, Muhammad Zulfadli Mehat, Nur Fariesha Md Hashim, Hafizah Abdul Hamid

“…Introduction Rapid technology development due to the introduction of Industrial Revolution 4.0 and Internet of Things has created a demand and gradual transition from traditional teaching and learning to technology-based learning in higher education, including healthcare education. …”
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Smoking cessation interventions for people living in rural and remote areas: a systematic review protocol by Billie Bonevski, Eliza Skelton, Alistair Lum, Kristen Louise McCarter, Tonelle Handley, Lucy Judd

“…The results will be disseminated through peer-reviewed publication and at conferences by presentations.PROSPERO registration number 177398.…”
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Evaluation of mobile health applications using the RE-AIM model: systematic review and meta-analysis by Emanuele Louise Gomes de Magalhães Jorge, Emily de Souza Ferreira, Michele Duarte Pereira, Ana Luiza Paes Mingote, João Henrique Corrêa Silva, Tiago Ricardo Moreira, Rosângela Minardi Mitre Cotta

“…By highlighting the strengths and areas requiring improvement, the study provides important input for the future development of mobile health applications capable of achieving better clinical and health promotion outcomes.Systematic Review RegistrationPROSPERO. …”
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Using telehealth in motor neuron disease to increase access to specialist multidisciplinary care: a UK-based pilot and feasibility study by Susan Mawson, Cindy Cooper, Mike Bradburn, Pamela J Shaw, Esther V Hobson, Wendy O Baird, Ann Quinn, Theresa Walsh

“…The complexity of the intervention and heterogeneity of the patient population means that a randomised controlled trial may not be the best way to evaluate the further development and implementation of the TiM.Trial registration number ISRCTN26675465.…”
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Cognitive functioning and work-related outcomes of non-central nervous system cancer survivors: protocol for a systematic review with meta-analysis by Sofia Fernandes, Ana F Oliveira, Juliana D Reis, Ana Torres, Isabel M Santos, Diane Von Ah

“…The cumulative evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation system.Ethics and dissemination Ethics approval is not required since individual patient data will not be collected. …”
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Positive mental states and their relation to psychosocial resources: protocol of a systematic review focusing on cultural moderators by Klaus Lieb, Makiko Yamada, Sarah K Schäfer, Max Supke, Jana Meier, Hiro Taiyo Hamada, Michele Wessa

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A systematic review of military-to-civilian transition, The role of gender. by Alexandria Smith, Laura Rafferty, Bethany Croak, Neil Greenberg, Rafiyah Khan, Victoria Langston, Marie-Louise Sharp, Anne Stagg, Nicola Fear, Sharon Stevelink

“…Female veterans also struggled with the legacies of gender inequality, discrimination, and sexual assault which affected their development of a female veteran identity and affected the provision of services designed to meet their needs as a female. …”
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Patient satisfaction and quality of vision after bilateral implantation of enhanced monofocal IOL and mini-monovision: a prospective study by Andrea Llovet-Rausell, Jorge Navalón-Tortosa, Vasyl Druchkiv, Javier Coloma-Bockos, Jaime Moya-Roca, Fernando Llovet-Osuna

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Interventions to Foster Mental Health and Reintegration in Individuals Who Are Unemployed: Systematic Review by Sophia Helen Adam, Florian Junne, Svenja Schlachter, Miriam Mehler, Harald Gündel, Nicolas Rüsch, Jörn von Wietersheim, Katrin Elisabeth Giel, Stephan Zipfel, Rebecca Erschens

“… BackgroundUnemployment is a risk factor for the development and perpetuation of psychological distress. …”
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Association of the frequency of spicy food intake and the risk of abdominal obesity in rural Chinese adults: a cross-sectional study by Ling Wang, Yuqian Li, Chongjian Wang, Zhenxing Mao, Kaili Yang, Yuan Xue, Wenjie Li

“…Clarifying the mechanisms will facilitate the development of novel preventive and therapeutic approaches for abdominal obesity.Trial registration number ChiCTR-OOC-15006699…”
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Equity in protection: bridging global data gaps for an EBV vaccine—a systematic review and meta-analysis by Helen R Stagg, Ting Shi, Simran Kapoor, Marisa D Muckian, Vesa Qarkaxhija, Tomos Morgan

“…Pharmaceutical companies and researchers are placing substantial investment in the development of EBV vaccines. To ensure optimal vaccine roll-out, particularly in resource-limited settings, it is essential to have data on the age at acquisition of EBV. …”
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Effect of tree nuts on glycemic control in diabetes: a systematic review and meta-analysis of randomized controlled dietary trials. by Effie Viguiliouk, Cyril W C Kendall, Sonia Blanco Mejia, Adrian I Cozma, Vanessa Ha, Arash Mirrahimi, Viranda H Jayalath, Livia S A Augustin, Laura Chiavaroli, Lawrence A Leiter, Russell J de Souza, David J A Jenkins, John L Sievenpiper

“…<h4>Objective</h4>To provide better evidence for diabetes guidelines development, we conducted a systematic review and meta-analysis of randomized controlled trials to assess the effects of tree nuts on markers of glycemic control in individuals with diabetes.…”
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Ginseng supplementation and cardiovascular disease risk factors: a protocol for GRADE-assessed systematic review and dose-response meta-analysis by Sima Besharat, Ali Jafari, Kosar Kordkatuli, Helia Mardani, Fatemeh Mehdipoor, Pardis Bakhtiari Jami, Maryam Abbastabar, Mohammadali Vakili, Alireza Alaghi

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Intrauterine metformin exposure and adiposity outcomes in children: a systematic review and meta-analysis by George Tomlinson, Jill Hamilton, Kellie E Murphy, Jennifer Fu, Najla Tabbara, Denice S Feig

“…Grading of Recommendations Assessment, Development and Evaluation methodology was used to assess certainty of evidence.Results 18 studies reporting on 7975 children with metformin exposure in utero and over 1 million children without metformin exposure were included. …”
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