Effectiveness, safety and acceptability of medical abortion at home versus in the clinic: a systematic review and meta-analysis in response to COVID-19 by Katherine Gambir, Camille Garnsey, Kelly Ann Necastro, Thoai D Ngo

“…We used the Grading of Recommendations Assessment, Development and Evaluation approach to assess risk of bias by outcome and to evaluate the overall quality of the evidence.Results We identified 6277 potentially eligible published studies. …”
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Comparative analysis of carbomer polymers for pharmaceutical and cosmetic practice by H. P. Kukhtenko, T. V. Popova, Ie. V. Gladukh, O. S. Kukhtenko

“…When using carbomers in the pharmaceutical development of medicines, the results of additional studies on the compliance of quality with pharmacopoeial indicators should be provided in registration materials. …”
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Risk factors for delayed wound healing after anal fistula surgery: Protocol of a meta-analytic study. by Zubing Mei, Peixin Du, Ye Han, Yin Qu, Huili Tang, Yan Li, Huiyan Gao, Qingming Wang, De Zheng

“…The certainty of evidence will be evaluated with the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.<h4>Discussion</h4>This study's strengths include its comprehensive search strategy and rigorous methodology, providing a robust synthesis of risk factors. …”
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Quality of life in adults with Down syndrome: A mixed methods systematic review. by Ogochukwu Ann Ijezie, Jane Healy, Philip Davies, Emili Balaguer-Ballester, Vanessa Heaslip

“…The synthesised findings were grouped into the 8 core domains of quality of life: personal development, self-determination, interpersonal relations, social inclusion, rights, emotional, physical and material well-being. …”
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The role of compounded mouthwash with or without acyclovir in managing chemotherapy-induced oral mucositis in cancer patients: a randomized controlled trial by Amira Abdelnasser, Shaimaa El-Ashwah, Salma Elashwah, Mohamed Mabed

“…Logistic regression analysis corroborated the protective effect of the acyclovir-containing mouthwash against the development of mucositis, yielding an odds ratio (OR) of 2.444 with a p-value of 0.03. …”
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Evaluating respiratory depression after methadone administration in surgical patients: protocol for a systematic review and meta-analysis by Guido Mazzinari, Juan P. Cata, Eduardo Nunez-Rodriguez, Sarah Lumsden, Kate J. Krause, Nicolas Cortes, Evan D. Kharasch

“…The certainty of the evidence will be assessed using Grading of Recommendations Assessment, Development and Evaluation methodology.Ethics and dissemination Ethics approval is not necessary for this systematic review and meta-analysis. …”
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Personalised app-based relapse prevention of depressive and anxiety disorders in remitted adolescents and young adults: a protocol of the StayFine RCT by Claudi Bockting, Suzanne J Robberegt, Bas E A M Kooiman, Casper J Albers, Yvonne Stikkelbroek

“…Exploratory endpoints are monitoring and wearable outcomes.Ethics, funding and dissemination The study was approved by METC Utrecht and is funded by the Netherlands Organisation for Health Research and Development (636310007). Results will be submitted to peer-reviewed scientific journals and presented at (inter)national conferences.Trial registration number NCT05551468; NL8237.…”
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Acupotomy versus acupuncture for cervical spondylotic radiculopathy: protocol of a systematic review and meta-analysis by Jing Liu, Bin Chen, Cai Zhang, Ren-Pan Zhang, An-Yang Lin, Zhong-Biao Xiu, Hong-Jia Zhao

“…The Review Manager 5.3 will be used for meta-analysis and the evidence level will be assessed by using the method for Grading of Recommendations Assessment, Development and Evaluation. Continuous outcomes will be presented as the weighted mean difference or standardised mean difference with 95% CI, whereas dichotomous data will be expressed as relative risk with 95% CI. …”
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Physical literacy-based intervention for chronic disease management: a quasi-experimental study protocol by Alexandre Mouton, Jean-Pierre Weerts, Johannes Carl

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Physical functioning outcome measures in the lumbar spinal surgery population and measurement properties of the physical outcome measures: protocol for a systematic review by Alison B Rushton, Jai Mistry, Michael J Lukacs, Katie L Kowalski, Maren Goodman

“…Results will be disseminated through peer-reviewed journal publication and conference presentation.PROSPERO registration number CRD42021293880.…”
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Docosahexaenoic Acid Status in Pregnancy Determines the Maternal Docosahexaenoic Acid Status 3-, 6- and 12 Months Postpartum. Results from a Longitudinal Observational Study. by Maria Wik Markhus, Josef Daniel Rasinger, Marian Kjellevold Malde, Livar Frøyland, Siv Skotheim, Hanne Cecilie Braarud, Kjell Morten Stormark, Ingvild Eide Graff

“…As a result, the DHA status may not be optimal for child development and may increase the risk for maternal postpartum depression. …”
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The increased purchase of asthma medication for individuals born preterm seems to wane with age: A register-based longitudinal national cohort study. by Anne Louise de Barros Damgaard, Rasmus Gregersen, Theis Lange, Frederik Buchvald, Bo Mølholm Hansen, Gorm Greisen

“…Gestational age per se did not seem to be significant for the development of asthma-like symptoms: most of its effect could be explained by other perinatal factors.…”
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Sexual networks, sexual practices, and sexual health among youths in WHO-South East Asia Region: a scoping review protocol by Amrita Rao, Rashmi Shinde, Sheikh Mohammed Shahabuddin

“…All countries are striving to achieve the sustainable development goal by 2030; hence, it is important to prioritize healthcare services for youths. …”
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A qualitative study of the perspectives of health workers and policy makers on external support provided to low-level private health facilities in a Ugandan rural district, in mana... by Juliet Mwanga-Amumpaire, Joan N. Kalyango, Karin Källander, Radhika Sundararajan, Judith Owokuhaisa, Joseph Rujumba, Celestino Obua, Tobias Alfvén, Grace Ndeezi

“…Background With the under-five child mortality rate of 46.4 deaths per 1000 live births, Uganda should accelerate measures to reduce child deaths to achieve the Sustainable Development Goal 3. While 60–70% of frontline health services are provided by the private sector, many low-level private health facilities (LLPHF) are unregistered, unregulated, and often miss innovative and quality improvement strategies rolled out by the Ministry of Health. …”
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A randomized, controlled, 12-month trial on the effects of an interdisciplinary treatment approach in ESRD patients: study protocol of the smart and fit for kidney transplantation... by Helge Krusemark, Judith Kleemann, Julian Weigand, Dennis Kannenkeril, Katharina Heller, Tobias Hepp, Marc Albersmeyer, Doris Gerbig, Mario Schiffer

“…This deterioration may cause these patients to be classified as unsuitable for transplantation during the waiting period owing to frailty, poor body composition, or the development of new comorbidities. Studies have shown that physical exercise and tailored nutrition can maintain and improve physical performance and overall health status. …”
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Health service use among adults with cerebral palsy: a mixed methods systematic review protocol by Michael Walsh, Aisling Walsh, Manjula Manikandan, Claire Kerr, Jennifer M Ryan

“…Where possible a pooled analysis and aggregation of findings will be performed for quantitative and qualitative data, respectively, and Grading of Recommendations Assessment, Development and Evaluation (GRADE)/GRADE-CERQual (Confidence in Evidence from Reviews of Qualitative research) employed. …”
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Izuchenie vliyaniya sulodeksida na endoteliy-zavisimuyu vazodilatatsiyu mozgovykh sosudov u zhivotnykhso streptozototsin-indutsirovannym sakharnym diabetom by Ivan Nikolaevich Tyurenkov, Andrey Vladislavovich Voronkov, Anna Al'bertovna Slietsans, Evgenia Viktorovna Petrova, Grigoriy Leonidovich Snigur

“…Thus, impaired expression of antibodies against e-NOS and enhanced expression of anti-endothelin-1 antibodies (specific markers of endothelial disturbance) suggest development of ED in DM and endothelium protection by sulodexide that increases the eNOS level and decreases the endothelin-1 level thereby improving EDVD. …”
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Effect of adverse perinatal outcomes on postpartum maternal mental health in low-income and middle-income countries: a protocol for systematic review by Samrawit Mihret Fetene, Tsegaye Gebremedhin Haile, Abel Dadi

“…The review will be submitted for publication in a peer-reviewed journal.PROSPERO registration number CRD42023405980.…”
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The role of early weight bearing in the aftertreatment of unilateral displaced intraarticular calcaneal fractures: a systematic review and pooled analysis by Coen Verstappen, Mitchell L. S. Driessen, Lloyd Brandts, Michael J. R. Edwards, Martijn Poeze, Erik Hermans, Pishtiwan H. S. Kalmet

“…Future research should focus on the development of standardized, evidence-based after-treatment guidelines. …”
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What is the level of evidence for the amnestic effects of sedatives in pediatric patients? A systematic review and meta-analyses. by Karolline Alves Viana, Anelise Daher, Lucianne Cople Maia, Paulo Sucasas Costa, Carolina de Castro Martins, Saul Martins Paiva, Luciane Rezende Costa

“…The quality of the evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation approach.<h4>Results</h4>Fifty-four studies were included (4,168 participants). …”
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