HORMONE IMBALANCE AS A MANIFESTATION OF STRESS IN THE FORMATION OF OLIGOMENORRHEA IN TEENAGE GIRLS by В. Диннік, О. Диннік, С. Новохатська

“…Stress is implicated in the development of oligomenorrhea (OM), particularly in the context of the ongoing full-scale war in Ukraine. …”
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Effect of regulating gut microbiota using probiotics on functional changes in the brain: protocol for a systematic review by Tian Tian, Ling Zhao, Siyuan Zhou, Mingsheng Sun, Jiao Chen, Xixiu Ni, Lu Liu, Xiao Li, Fengmei Li

“…We will use risk of bias assessment and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to assess the quality of evidence. …”
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Quantitative examination of video-recorded NHS Health Checks: comparison of the use of QRISK2 versus JBS3 cardiovascular risk calculators by Christopher J Gidlow, Sarah Grogan, Lisa Cowap, Elizabeth Cottrell, Ruth Chambers, Naomi J Ellis, Victoria A Riley, Diane Crone, David Clark-Carter

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Urinary tract infections in postmenopausal women revisited (UTIr): a prospective observational cohort study to explore the urobiomes of postmenopausal women with and without recurr... by Marleen D. Hekker, Tamara N. Platteel, Roderick P. Venekamp, Janetta Top, Suzanne E. Geerlings, Constance Schultsz, Marjon G.J. de Vos, Janneke H. H. M. van de Wijgert

“…While Escherichia coli is the primary cause of most UTIs in premenopausal women, this may not hold true for postmenopausal women. To facilitate development of novel diagnostics, preventive interventions, and clinical management of RUTI in postmenopausal women, it is essential to strengthen the biological evidence base. …”
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Perioperative temperature management and coagulation: effects of mild hypothermia in a prospective study by Alena Trčková, Tereza Bönischová, Tereza Bönischová, Hana Zelinková, Petr Štourač, Petr Štourač

“…BackgroundPerioperative hypothermia is a common complication of general and regional anesthesia in children and is a known risk factor for the development of coagulation disorders. The primary aim of the study was to assess the occurrence of coagulopathy in hypothermic pediatric patients (0–18 years) undergoing arthroscopic surgery and open abdominal surgery. …”
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Effectiveness of eHealth for Medication Adherence in Renal Transplant Recipients: Systematic Review and Meta-Analysis by Lili Zhou, Ke Cheng, Linbin Chen, Xinyi Hou, Jingjing Wan

“…Risk of bias and evidence quality were evaluated using the Cochrane Risk of Bias 2 tool and the Grading of Recommendations, Assessment, Development, and Evaluation approach, respectively. …”
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Perceptions of, Barriers to, and Facilitators of the Use of AI in Primary Care: Systematic Review of Qualitative Studies by Héctor Martínez-Martínez, Julia Martínez-Alfonso, Belén Sánchez-Rojo-Huertas, Valeria Reynolds-Cortez, Andrea Turégano-Chumillas, Victoria A Meseguer-Ruiz, Shkelzen Cekrezi, Vicente Martínez-Vizcaíno

“…A thematic synthesis approach was used to structure the results, and the Grading of Recommendations Assessment, Development, and Evaluation–Confidence in the Evidence From Reviews of Qualitative Research (GRADE-CERQual) tool was used to assess the confidence in each finding. …”
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User journey method: a case study for improving digital intervention use measurement by Lauri Lukka, Maria Vesterinen, Antti Salonen, Vilma-Reetta Bergman, Paulus Torkki, Satu Palva, J. Matias Palva

“…Conclusion The user journey method allowed for the comprehensive evaluation of the six intervention elements, and enabled identifying use barriers expediting iterative intervention development and implementation. Trial registration ClinicalTrials.gov, NCT05426265. …”
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Primary staging with 2[18F]-FDG-PET/CT and -PET/MRI and radiotherapy response evaluation with MRI in uterine cervical cancer: an interim analysis of a prospective clinical trial by Maja Aasa, David Lindquist, Ulrika Ottander, Sara N. Strandberg

“…With the technical development in diagnostic imaging, continuous prospective evaluation of the different imaging methods contributing to stage determination is warranted. …”
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Prevalence of multidrug-resistant bacteria in healthcare and community settings in West Africa: systematic review and meta-analysis by Moustapha Diop, Oumar Bassoum, Abdourahmane Ndong, Fatimata Wone, Ajuamendem Ghogomu Tamouh, Maguette Ndoye, Tracie Youbong, Sokhna Moumy Mbacké Daffé, Romziath Olouwakemi Radji, Mamadou Wagué Gueye, Ndeye Aissatou Lakhe, Bécaye Fall, Papa Samba Ba, Adama Faye

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Cognitive-motor dual-task training on gait and balance in stroke patients: meta-analytic report and trial sequential analysis of randomized clinical trials by Lu Zhang, Jiangping Ma, Xiaoqing Liu, Aiping Jin, Kai Wang, Xiaobing Yin

“…The evidence for each outcome was evaluated according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) Working Group criteria. …”
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Phase 1 Trials of Gatralimab, a Next-Generation Humanized Anti-CD52 Monoclonal Antibody, in Participants with Progressive Multiple Sclerosis by Fredrik N. Albach, Christian Geier, Christian Keicher, Maximilian G. Posch, Stephan J. Schreiber, Gerald Grütz, Levent Akyüz, Xiaodong Luo, Annaig Le-Halpere, Philippe Truffinet, Frank Wagner

“…Although gatralimab is no longer in development for MS, insights from these trials may inform the development of comedication regimes of future anti-CD52 mAbs and subcutaneous formulations of other lymphocyte-depleting mAbs. …”
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Parallels of structural-functional parameters the myocardium, C-type natriuretic peptide and endothelin-1 plasma concentrations in women with uncomplicated essential hypertension by V. V. Petrovska, B. M. Zhebel

“…The development of endothelial dysfunction (DE)plays an important role in the pathogenesis of essential hypertension (EH). …”
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Nurse-led weaning protocols—a systematic review and meta-analysis by Yingying Wang, Yingying Wang, Yan Wang, Su Gu, Liqun Zhu, Ruixiao Jia, Min Tan, Shaoyong Ma

“…The certainty of evidence was assessed using the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) profiler Guideline Development Tool.ResultsOur analysis included a total of six relevant studies. …”
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A phase 3 randomised study of enzalutamide plus leuprolide and enzalutamide monotherapy in high-risk non-metastatic hormone-sensitive prostate cancer with rising PSA after local th... by Ugo De Giorgi, Martin Gleave, Brad Rosbrook, Stephen J Freedland, Qi Shen, Jennifer Sugg, Gabriel P Haas, Neal D Shore

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The feasibility of conducting a randomized controlled trial that compares immediate versus optional delayed surgical repair for treatment of acute Anterior cruciate ligament injury... by Feryal Ghafelzadeh Ahwaz, Annemie Smeets, Stijn Bogaerts, Pieter Berger, Koen Peers

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Efficacy of virtual reality assisted guided imagery (VRAGI) in a home setting for pain management in patients with advanced cancer: protocol for a randomised controlled trial by Andrew Todd, Rosalba Hernandez, George Hartshorn, Matthew Browning, Kapil Chalil Madathil, Fredric Mau, Shyam Ranganathan, Jeff Bertrand, Allison Maynard, Olivia McAnirlin, Kailan Sindelar, Teny Henry Gomez

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TO A QUESTION OF BACKGROUND SUBTRACTION AT AN INDIVIDUAL RADIATION CONTROL by A. I. Grigorev

“…In article one provision of the Methodical Guideline MG 2.6.1.3015-12 developed in 2012, – refusal of subtraction of a contribution of external natural radiation at the organization and carrying out an individual dosimetry control is discussed. …”
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Label-Free Electrochemical Cell-Based Biosensor for Toxicity Assay of Water-Soluble Form of Phosphatidylcholine by Veronica V. Pronina, Lyubov V. Kostryukova, Sergey V. Ivanov, Elena G. Tichonova, Alexander I. Archakov, Victoria V. Shumyantseva

“…<b>Methods:</b> In this work, the electrochemical mediator-free and reagent-free analysis of cell lines based on the registration of electrochemical profiles of membrane proteins was developed. …”
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Challenges and insights from implementing clinical decision support systems for radiologic imaging: experience from the MIDAS trial by Thomas Kroencke, Stijntje W. Dijk, Moritz C. Halfmann, Claudia Wollny, Joerg Barkhausen, Olav Janssen, Dimitris Rizopoulos, M. G. Myriam Hunink

“…Abstract Clinical decision support systems (CDSSs) have been developed to give guidance for referring physicians to make appropriate decisions at the point of care. …”
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