Genome mining identifies a diversity of natural product biosynthetic capacity in human respiratory Corynebacterium strains by Ashley L. Cunningham, Ilya Y. Zhbannikov, Rachel Myers, Tommy H. Tran, Wei Gao, Katherine P. Lemon, Jhoanna N. Aquino, Jillian H. Hurst, Joon Won Yoon, Patrick C. Seed, Matthew S. Kelly

“…Among 161 genomes, we identified 672 BGCs, 495 of which were unique, including polyketide synthase, non-ribosomal peptide synthetase, ribosomally synthesized and post-translationally modified peptide, and siderophore families. …”
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Bibliometric-based visualization analysis of hotspots and trends in falls research among older hospitalized patients (2013–2023) by Yang Dong, Dandan Liu, Ya Yu, Ziyu Xiong, Hongying Rao

“…Furthermore, epidemiology, aging population dynamics, and health outcomes continue to be enduring areas of interest for researchers post-2018 and warrant additional emphasis from scholars.…”
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Role of long non-coding RNA in plant flowering regulation(长链非编码RNA在植物开花调控中的作用) by 郑羽琪(ZHENG Yuqi), 苏逸然(SU Yiran), 彭俊睿(PENG Junrui), 杜佳宏(DU Jiahong), 武亮(WU Liang)

“…Within these pathways, long non-coding RNA (lncRNA) works in conjunction with related proteins to regulate key factors at transcriptional, post-transcriptional and epigenetic levels. They achieve this by modifying histones, participating in alternative splicing, and producing or competitively binding to microRNA (miRNA) and small interfering RNA (siRNA), thereby either promoting or inhibiting flowering. …”
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A Novel High-Content Screening-Based Method for Anti-Trypanosoma cruzi Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Diogo Crispim Nascimento Portella, Erik Aranha Rossi, Bruno Diaz Paredes, Tanira Matutino Bastos, Cássio Santana Meira, Carolina Vasques Kymie Nonaka, Daniela Nascimento Silva, Alex Improta-Caria, Diogo Rodrigo Magalhaes Moreira, Ana Cristina Lima Leite, Gevanio Bezerra de Oliveira Filho, José Maria Barbosa Filho, Ricardo Ribeiro dos Santos, Milena Botelho Pereira Soares, Bruno Solano de Freita Souza

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Drug tapering in animal research: current practices and challenges by Yatong Zhang, Yatong Zhang, Mengrui Chen, Mengrui Chen, Tongtong Jiang, Tongtong Jiang, Qianfang Fu, Qianfang Fu, Rong Ma, Rong Ma, Lianghui Nie, Lianghui Nie, Yuqiong You, Yuqiong You, Shuqi Gao, Shuqi Gao, Ping Rong, Ping Rong

“…The outcomes of tapering were classified into drug discontinuation, low-dose maintenance, and drug substitution, with all studies reporting the effects post-tapering.ConclusionThe methods of drug tapering in animal studies are influenced by multiple factors, including disease characteristics, treatment duration, animal tolerance, and specific goals. …”
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Delayed treatment with hydro-ethanolic extract of Khaya grandifoliola protects mice from acetaminophen-hepatotoxicity through inhibition of c-Jun N-terminal kinase phosphorylation... by Arnaud Fondjo Kouam, Ibrahim Njingou, Nina Jeannette Pekam Magoudjou, Hamed Bechir Ngoumbe, Philipe Herman Nfombouot Njitoyap, Elisabeth Menkem Zeuko'o, Frédéric Nico Njayou, Paul Fewou Moundipa

“…Our findings demonstrate that post-treatment with KgE protects the mouse liver from APAP-hepatotoxicity through the inhibition of JNK activation and mitochondrial dysfunction.…”
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A quantitative multi-parameter mapping protocol standardized for clinical research in multiple sclerosis by Henri Trang, Tim J. Hartung, Qianlan Chen, Stefan Hetzer, Claudia Chien, Pia S. Sperber, Tanja Schmitz-Hübsch, Susanna Asseyer, Rebekka Rust, Darius Mewes, Lina Anderhalten, Michael Sy, Alexander U. Brandt, Carsten Finke, Friedemann Paul

“…We used a fast multi-parameter mapping (MPM) protocol for clinical routine at 3T to reconstruct whole-brain quantitative maps of magnetization transfer saturation (MT), proton density (PD), longitudinal (R1), and transverse relaxation rate (R2*) with 1.6 mm isotropic resolution. We report reference MPM values from a healthy population with age and gender distributions typical of multiple sclerosis in whole brain white matter (WM), T2-weighted WM hyperintensities, cortical grey matter and deep grey matter regions and present post-processing optimizations including integration of lesions and normalization of PD maps against cerebrospinal fluid (CSF) for standardized research in multiple sclerosis (MS) and potentially also in related disorders. …”
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Surface electromyography character of upper limb muscle after open reduction combine with ulnar osteotomy in children with neglected Monteggia fracture by Hailing Qiu, Hailing Qiu, Tingzhi Li, Fanling Li, Siqi Zhang, Xiangling Wu, Jing Yang, Xin Li, Ke Fang, Jie Wen, Sheng Xiao

“…The root mean square (RMS) values of sEMG signals, co-contraction ratio, and elbow joint function scores were compared between pre- and post-operation periods as well as between the affected side and unaffected side.ResultsThe preoperative maximum grip strength, as well as the average RMS values of flexor carpi radialis and average RMS value of extensor carpi ulnaris on the affected side were significantly lower. …”
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Auditory evoked delta brushes involve stimulus-specific cortical networks in preterm infants by Anna Kaminska, Dorothée Arzounian, Victor Delattre, Jacques Laschet, Jean-François Magny, Shushanik Hovhannisyan, Mostafa Mokhtari, Antoine Manresa, Anne Boissel, Lisa Ouss, Lucie Hertz-Pannier, Catherine Chiron, Fabrice Wendling, Yves Denoyer, Mathieu Kuchenbuch, Jessica Dubois, Roustem Khazipov

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Verification of Lactobacillus brevis tolerance to simulated gastric juice and the potential effects of postbiotic gamma-aminobutyric acid in streptozotocin-induced diabetic mice by Amro Abdelazez, Heba Abdelmotaal, Smith Etareri Evivie, Maha Bikheet, Rokayya Sami, Hassan Mohamed, Xiangchen Meng

“…The body weight and hyperglycemia in the blood were assessed weekly, post-euthanasia blood plasma parameters, insulin, and histological examination were evaluated. …”
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THE STUDY "REGISTER OF PATIENTS AFTER ACUTE STROKE (REGION)". PART 2. OUTPATIENT PROSPECTIVE REGISTER OF PATIENTS AFTER ACUTE STROKE (ACCORDING TO THE RESULTS OF THE PILOT PHASE OF... by S. А. Boytsov, M. M. Loukianov, S. S. Yakushin, S. Yu. Martsevich, L. V. Stakhovskaya, A. N. Vorobyev, A. V. Zagrebelnyy, N. P. Kutishenko, A. N. Kozminsky, K. A. Moseichuk, K. G. Pereverzeva, E. A. Pravkina, E. N. Belova, E. V. Kudryashov, A. D. Deev

“…Majority of patients at the outpatient phase  received inadequate treatment for cardiovascular risk decrease, especially before  reference ACVA. The ACVA-FV register patients as compared to the ACVA-AR ones (who had experienced ACVA on an average 4.8 years earlier) were more often (p<0.05) examined by instrumental and laboratory methods of diagnostics during the post-stroke follow-up in outpatient settings. …”
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Simulation of frost damage on overwintering fruiting parent branches in Actinidia arguta by QU Jing, WANG Nan, LI Sihu, LI Hualong, WU Jinwen

“…By observing the freezing point in the cells of the fruiting mother branches of four varieties in Liaoning, as well as measuring membrane leakage, post-frost growth recovery and tissue browning, damage caused by simulated frost was observed in A. arguta fruiting mother branches. …”
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„Nasze ścieżki staną się drogami”: Ekogroznawcze refleksje wokół Death Stranding Hideo Kojimy by Karol Zaborowski

“…Chang’s postulates from the manifesto of environmentally conscious game design, as well as references to works in the field of post-humanistic philosophy. …”
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Motor induced syncope after cerebral infarction: A case report and literature review by Zihan Zhao, Ranran Wang, Lihua Gao, Meijing Zhang

“…Cardio-cerebral syndrome refers to cardiac injury following cranial brain injury, representing a critical complication of stroke associated with high morbidity and mortality. …”
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The cost-effectiveness of peer education on medication adherence in the elderly with hypertension: a randomized controlled trial by Hossein Ranjbar, Kobra Sadeghi-Vazin, Mahmoud Bakhshi

“…Data was collected before the intervention, immediately after intervention, and at 3 and 6 weeks post-intervention using the Morisky Medication Adherence Scale. …”
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The Effectiveness of Treatment Is Based on the Mentalization of Object Relations and Feelings of Shame and Guilt in Conflicting Mother-Child Relationships by Parvin Roosta, Sayed Abdollah sadat Bahreinian, Ghasem Ahi, Mohammad Hassan Ghanifar

“…Methods: This research method was semi-experimental and pre-test-post-test with a control group. The statistical population of this research included all mothers and adolescents with conflicting relationships who were referred to counseling centers in Shiraz in 2022. …”
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Missed opportunities: poor linkage into ongoing care for HIV-positive pregnant women in Mwanza, Tanzania. by Deborah Watson-Jones, Rebecca Balira, David A Ross, Helen A Weiss, David Mabey

“…Only 32% of 244 women followed to four months post-partum had attended an HIV clinic and been assessed for HAART eligibility. …”
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Lumbosacral (myelo) meningoceles in dogs, related tethered cord syndrome, and their surgical management: review of the literature and clinical experience by Patrick Roynard, Patrick Roynard, Curtis Wells Dewey

“…Pelvic limb deficits improve post-surgically in most cases (14/17 [82%] cases with pre-operative deficits and follow-up ≥1 month) albeit sometimes only marginally. …”
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Impact of microneedling on reducing perioral wrinkles by Fariba Iraji, Amir Hossein Siadat, Fatemeh Mokhtari, Mohsen Hosseini, Maryam Fatahinasab

“…Methods: A clinical trial was conducted on 30 women referred to a skin clinic in Isfahan, Iran, from December 22, 2021, to June 20, 2022. …”
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Case Report: Hemodynamic challenges during the anesthetic management of a patient who presented with a cervical vagal schwannoma in southern Ethiopia: a rare clinical case by Tajera Tageza Ilala, Gudeta Teku Ayano, Mengistu Yinges Kebede

“…The patient was awakened, extubated, and successfully transferred to the post-anesthesia care unit at the end of the procedure. …”
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