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2821
Hepatocellular carcinoma drug resistance models
Published 2025-05-01“…Although drug therapy has been well developed and applied, its clinical efficacy is limited due to primary or acquired drug resistance in most HCC patients. Therefore, it is of great clinical significance to elucidate the key molecular mechanisms of resistance and improve the sensitivity of HCC cells to drugs. …”
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2822
In Vitro Antimicrobial Activity of Some Medicinal Plants against Human Pathogenic Bacteria
Published 2019-01-01“…The result indicated that most of the extracts exhibited antimicrobial properties. …”
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2823
Predicting DNA-binding proteins and binding residues by complex structure prediction and application to human proteome.
Published 2014-01-01“…This work presents a highly reliable computational technique for predicting DNA-binding function at the level of protein-DNA complex structures, rather than low-resolution two-state prediction of DNA-binding as most existing techniques do. The method first predicts protein-DNA complex structure by utilizing the template-based structure prediction technique HHblits, followed by binding affinity prediction based on a knowledge-based energy function (Distance-scaled finite ideal-gas reference state for protein-DNA interactions). …”
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2824
Teaching History from a biblical integration perspective in an Adventist high school in Romania
Published 2025-04-01“…Teachers and students studying history recognize that most historical narratives include philosophies and beliefs antagonistic to the biblical worldview. …”
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2825
BTK inhibition in primary central nervous system lymphoma: mechanisms, clinical efficacy, and future perspectives
Published 2024-12-01“…The prognosis of primary central nervous system lymphoma (PCNSL) patients is relatively poor, and there is currently no standard treatment plan. Most patients choose high-dose chemotherapy based on methotrexate. …”
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2826
Examining the Challenges faced in Service Delivery by South African Rural Communities after 28 years of Democratic Government Administration: The Case of Sekhukhune Municipal Areas...
Published 2025-06-01“…The purpose of this study was to examine and discuss the challenges faced by South African rural communities in the provision of public services with specific reference to Sekhukhune District Municipal (SDM) areas in Limpopo province. …”
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2827
The biology of chronic myeloid leukemia: an overview of the new insights and biomarkers
Published 2025-05-01“…Among these, leukemic stem cells, miRNAs, extracellular vesicles, and additional BCR::ABL1 mutations, with particular reference to the ASXL1 gene, have been the most extensively investigated. …”
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2828
Interventions to Improve Sexual Health in Iranian Cancer Patients: A Systematic Review
Published 2025-07-01“…Results: All studies (n = 291) were reviewed and 20 met the inclusion criteria. Most studies (n = 18) focused on breast cancer patients and were conducted in Tehran (n = 11). …”
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2829
Identification of benthic diatoms isolated from the eastern tidal flats of the Yellow Sea: Comparison between morphological and molecular approaches.
Published 2017-01-01“…The Blast search on NCBI's Genebank indicated that the reference sequences for most of the species were absent for the benthic diatoms. …”
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2830
Contested Meanings of Hate Speech and the Post-Truth Condition on Digital Platforms
Published 2025-05-01“…From a large dataset of 289,933 messages, we identified the 10 most relevant themes. We further used articulation theory to analyze different political and social articulations of hate speech. …”
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2831
Thermal properties of mineral wool insulation recovered from construction and demolition waste
Published 2022-03-01“…Mineral wool is one of the most commonly used types of thermal insulation in the European Union at the present, however, it generates massive amounts of waste. …”
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2832
Human Action Recognition Based on The Skeletal Pairwise Dissimilarity
Published 2025-06-01“…The article presents the human figure representing approach based on pairwise dissimilarity function of skeletal models and a set of reference objects, also known as a basic assembly. …”
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2833
Epilepsy and a woman – a woman has been found!
Published 2022-10-01“…Currently, the number of antiepileptic drugs (AEDs) has been growing. While choosing the most optimal AEDs by criteria of their efficacy, tolerability and retention time on therapy, many clinical factors, individual biological characteristics of any certain patient, as well as socio-economic aspects should be taken into account, including those associated with the burden on the health care system. …”
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2834
Optimization of Ultrasonic-Enzyme Synergistic Extraction of Proanthocyanidins from Jujube: Purification, Characterization, and Bioactivity Study
Published 2025-01-01“…They can be utilized for the extraction and purification of proanthocyanidins, offering a reference for the expansion of natural sources of proanthocyanidins and the development of functional foods.…”
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2835
The Comparison of Activation Functions in Feature Extraction Layer using Sharpen Filter
Published 2025-06-01“…The findings revealed that ReLU consistently outperformed other activation functions by achieving the lowest MSE values, making it the most effective choice for feature extraction tasks using sharpening filters. …”
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2836
A Study on the Price Spatial Differentiation and Influencing Factors of Rural Homestay in Suzhou Based on the Hedonic Price Model
Published 2025-05-01“…The results show that (1) the high-priced rural homestays in Suzhou are concentrated in the lake island resort with good natural environment and perfect infrastructure; (2) the location, facility quality, and network score of rural homestays have a positive impact on housing prices; (3) the parking lot of rural homestays hurts housing prices; (4) the quality of rural residential buildings and facilities has the most significant positive impact on housing prices. …”
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2837
Viagens ecléticas, residências e obras: Maria Graham artista-autora-viajante
Published 2020-11-01“…The case of the traveller Maria Graham, whose critical experiences echo in about 10 travel books, among them The Diary of a Journey to Brazil and a Stay in this Country during the years of 1821, 1822 and 1823, is exemplary – especially considering the period of socio-political consciousness in reference. Her literary work intertwines narrative with images, under the at most scientific requirements, and it can be related to the works of some other European authors who followed similar scientific and artistic missions, shaping an image of Brazil as seen by its visiting artists from the 16th century on. …”
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2838
Patrones constructivos de enfriamiento pasivo para mampostería cerámica de bajo costo
Published 2021-02-01“…For the analysis, the models are exposed to the most extreme climatic conditions of a hot semi-arid climate taking as reference the periods of highest temperature and solar radiation in Cúcuta, Colombia to determine the thermal performance of the different configurations and evaluate the viability of the solutions. …”
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2839
NUMBER OF RUNS VARIATIONS ON AUTODOCK 4 DO NOT HAVE A SIGNIFICANT EFFECT ON RMSD FROM DOCKING RESULTS
Published 2021-05-01“…However, it is not known exactly how the most ideal runs in the docking process with AutoDock 4. …”
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2840
Determination of the Error in Transferring of Length Unit’s Size when Measuring the Nanoparticles’ Diameter Using an Analyzer of Particles’ Differential Electrical Mobility
Published 2021-10-01“…This measurement method is the most accurate in the field of measuring the diameters of particles in aerosols, therefore, the error in the transmission of particle size must be set as for a standard.The paper describes the physical principles of measurement by this method and presents an equation for determining the diameter of nanoparticles. …”
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