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A gap-free reference genome of Populus deltoides provides insights into karyotype evolution of Salicaceae
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Integrating parental genomes to reduce reference bias and identify intramuscular fat genes in Qinchuan Black pigs
Published 2025-07-01“…Abstract Background Traditional genomic analysis relies on a single reference genome, which struggles to effectively characterize the genetic diversity among populations. …”
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Construction of the porcine genome mobile element variations and investigation of its role in population diversity and gene expression
Published 2024-12-01“…Finally, we provide a high-quality SNP–MEV reference haplotype panel to impute MEV genotypes from genome-wide SNPs. …”
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Complete mitochondrial genomes of the Prototheca genus: comparative genomics and evolutionary insights
Published 2025-08-01“…Abstract Background Prototheca (Chlorophyta: Trebouxiophyceae) is a genus of non-photosynthetic microalgae that causes increasingly frequent infections in both humans and animals, collectively referred to as protothecosis The genetic landscape of the Prototheca algae has remained largely uncharted until recent advances in sequencing and genomics. …”
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The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs
Published 2024-11-01“…Based on the deep sequencing (~25.95×) of these pigs, we identify 63.62 million genomic variants, and provide a population-specific reference panel to improve the imputation performance of Chinese domestic pig populations. …”
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Genome assembly and population analysis of tetraploid marama bean reveal two distinct genome types
Published 2025-01-01“…Overall, this study presents the first high-quality genome assembly of marama bean, offering a valuable genomic reference for understanding its unique biology and highlighting its potential for crop improvement in challenging environments.…”
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Extending gene set variation analysis with a reference dataset to stabilize scores
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Progress in plant genome sequencing: research directions
Published 2019-02-01“…In this review, an analysis of sequencing technologies development and the construction of “reference” genomes of plants is performed. A comparison of the methods of targeted sequencing based on the use of the reference DNA sequence is accomplished.…”
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Sequence-based prioritization of i-Motif candidates in the human genome
Published 2025-08-01“…The human reference genome (hg38) was scanned using a custom regular expression targeting cytosine-rich motifs, followed by scoring each sequence with the PSSM. …”
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Lactuca super-pangenome provides insights into lettuce genome evolution and domestication
Published 2025-08-01“…Here, we report the high-quality reference super-pangenome for the Lactuca genus by integrating 12 chromosome-scale genomes from representative cultivated lettuce morphotypes, landrace, and wild relatives, and investigate lettuce genome evolution and domestication. …”
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The Impact of Narratives on the Legal and Regulatory Discourse of Heritable Human Genome Editing
Published 2025-07-01“…Notably, Heritable Human Genome Editing (HHGE), which refers to the editing of germline cells for the purpose of reproduction, has significant potential for therapeutic application. …”
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Refinement of the Reference Viral Database (RVDB) for improving bioinformatics analysis of virus detection by high-throughput sequencing (HTS)
Published 2025-07-01“…In this study, we have refined our original comprehensive Reference Virus Database (RVDB) for greater accuracy of virus detection with a reduced computational burden. …”
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The first chromosome-level genome of the lappet moth Trabala vishnou (Lepidoptera: Lasiocampidae)
Published 2025-07-01“…A total of 1,630 non-coding RNAs and 12,895 protein-coding genes have been identified within the genome. The first chromosome-level genome of T. vishnou serves as a valuable reference for elucidating the evolution of functional traits in Lasiocampidae family and will facilitate the development of strategies for controlling defoliating pests.…”
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Chromosome-level genome assembly of Marco Polo Blister Beetle (Hycleus marcipoli)
Published 2025-08-01“…Despite the availability of fragmented genomes of Hycleus, a high-quality, chromosome-level genome reference is not yet available for this diverse genus. …”
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Ecological diversification of sea catfishes is accompanied by genome-wide signatures of positive selection
Published 2024-11-01“…Here, we generate and analyze one long-read reference genome and 66 short-read whole genome assemblies, in conjunction with genomic data for 54 additional species. …”
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Universal amplification and sequencing of foot-and-mouth disease virus complete genomes using nanopore technology
Published 2025-08-01“…A bioinformatics pipeline was used to assemble genomes based upon blastn and reference assembly. …”
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Oar_Finn: the genome assembly and annotation of an exceptionally fertile Finnsheep (Ovis aries) Ewe
Published 2025-08-01“…Abstract Objectives Finnsheep, a highly prolific breed of sheep, has been globally exported for improving fertility traits of many sheep breeds. Published genomic studies of Finnsheep have been based on Texel and Rambouillet reference genomes, which may not capture its unique genetic features. …”
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The chromosome-level genome assembly and annotation of the silver-lipped pearl oyster, Pinctada maxima
Published 2025-07-01“…However, the lack of genomic reference limits our in-depth understanding of this species in genome-based breeding, conservation, evolution and adaptation. …”
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