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Comparative efficacy of different doses of platelet-rich plasma injection in the treatment of knee osteoarthritis: a systematic review and network meta-analysis
Published 2025-03-01“…Conclusion This network meta-analysis highlights the superior efficacy of higher-dose PRP, particularly PRP3, in reducing pain and improving function in patients with knee osteoarthritis.…”
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Spatiotemporal Analysis and Anomalous Trends of Asia AOD (2001–2024): Insights from a Deep Learning Fusion Model and EOF Decomposition
Published 2025-05-01“…Spatio-temporal analysis, conducted using Empirical Orthogonal Function (EOF) decomposition, reveals that AOD concentrations across Asia are strongly influenced by anthropogenic factors, including industrial activities, transportation emissions, and biomass burning. …”
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Deep brain stimulation of pallidal versus subthalamic for patients with Parkinson's disease: a meta-analysis of controlled clinical trials
Published 2016-06-01“…Meanwhile, the STN-DBS is superior at reducing the LED, whereas the GPi-DBS shows a significantly greater reduction in BDI score after DBS. Keywords: Parkinson disease, deep brain stimulation, subthalamic nucleus, globus pallidus internus…”
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Efficacy and safety of belimumab therapy for patients with lupus nephritis: A meta‐analysis and a propensity score‐matched case–control study
Published 2023-07-01“…Abstract Objective In this study, we performed a meta‐analysis and a propensity score‐matched case–control study to evaluate the efficacy and safety of belimumab in patients with lupus nephritis (LN). …”
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Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis.
Published 2016-01-01“…Secondary outcomes were fasting plasma glucose, body weight, blood pressure, heart rate, lipids, liver function tests, creatinine and adverse events including infections. …”
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Reinforcing gut integrity: A systematic review and meta-analysis of clinical trials assessing probiotics, synbiotics, and prebiotics on intestinal permeability markers
Published 2025-06-01“…Background: Given the magnitude and variety of chronic metabolic disease linked to increased intestinal permeability, appropriate strategies to reinforce gut barrier function are urgently needed. Methods: This systematic review and meta-analysis explores the effects of pro- and synbiotic, or prebiotic administration, on various intestinal permeability markers. …”
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Effectiveness of high-intensity laser therapy in the treatment of shoulder impingement syndrome: a systematic review and meta-analysis of randomised clinical trials
Published 2025-03-01“…Results Nineteen studies were included, generally presenting a low RoB, except for outcome data measurement and bias due to deviations from the intended intervention. RCTs reported a reduction in pain and an improvement in functionality in the meta-analysis. …”
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Association between dietary index for gut microbiota and diarrhea among US adults: a cross-sectional analysis of NHANES 2005–2010
Published 2025-04-01“…Notably, the “beneficial component” was found to have a more pronounced effect on reducing diarrhea risk.ConclusionBased on a large representative population, our findings suggest that a higher DI-GM score is significantly associated with a lower risk of diarrhea, underscoring the importance of overall dietary patterns in maintaining gut function and homeostasis.…”
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Proximal Articular Set Angle Correction with the Reverdin–Isham Osteotomy in Mild and Moderate Hallux Valgus: A Systematic Review and Meta-Analysis
Published 2025-02-01“…Objective: The main objective of this analysis was to evaluate the correction of radiological angles (PASA, IMA, and HVA), the improvement in functionality according to the AOFAS scale, pain reduction, and patient satisfaction. …”
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Nutritional Enhancement of Crackers Through the Incorporation of By-Products from the Frozen Pumpkin Industry
Published 2025-07-01“…The inclusion of pumpkin flour significantly increased β-carotene content (up to 2.36 mg/100 g), total phenolics, and antioxidant activity of the baked crackers. Proximate analysis showed a marked improvement in fiber content and a slight reduction in energy value compared to wheat flour. …”
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The effect of mild to moderate knee osteoarthritis on gait and three-dimensional biomechanical alterations
Published 2025-04-01“…BackgroundKnee Osteoarthritis (KOA) is a prevalent chronic degenerative joint disease, particularly among the elderly, leading to pain, stiffness, and diminished functionality. The progression of KOA is often associated with significant changes in gait and biomechanics, yet detailed investigations of these changes—especially in early to moderate stages—remain limited. …”
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Investigation of Antioxidative Enzymes and Transcriptomic Analysis in Response to Foliar Application of Zinc Oxide Nanoparticles and Salinity Stress in <i>Solanum lycopersicum</i>
Published 2025-07-01“…Differential expression analysis was used to identify increased and reduced gene clusters, and gene enrichment analysis was used to identify over- and under-expressed genes under the treatment. …”
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The Efficacy of Hyaluronic Acid in Reducing Pelvic Adhesions in Patients Undergoing Gynecologic Laparoscopic Surgery: A Meta‐Analysis of Randomized Clinical Trials
Published 2025-06-01“…Hyaluronic acid gel functions as a physical barrier, potentially reducing the formation of postoperative adhesions by minimizing tissue contact during the healing process. …”
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Psycho-educational interventions for children and young people with Type 1 Diabetes in the UK: How effective are they? A systematic review and meta-analysis.
Published 2017-01-01“…Most interventions were delivered by non-psychologists and targeted adolescents with more than one year duration of diabetes. Meta-analysis of nine of these trials (N = 1,838 participants) showed a non-significant reduction in HbA1c attributable to the intervention (pooled SMD = -0.06, 95% CI: -0.21 to 0.09). …”
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Tuning surface properties of thiophene-based thin films on glass substrates for cancer cell adhesion, drug release control, and computational analysis
Published 2025-06-01“…SEM analysis and roughness measurements were used to assess their structural and functional properties. …”
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Surgical vs conservative: what is the best treatment of acute Rockwood III acromioclavicular joint dislocation? A systematic review and meta-analysis
Published 2025-03-01“…Conclusion: The results showed no significant differences in terms of patient-reported or objective functional outcomes between the two treatment groups. …”
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Exploring synergistic effects: Atorvastatin and electrical stimulation in spinal cord injury therapy
Published 2025-06-01“…In addition, astrocyte protein levels were lower in the SCI+OFS+ATR group compared with others. Histological analysis showed a significant reduction in white and gray matter after SCI, but less white and gray matter volume loss was found in the groups receiving therapies (SCI+OFS+ATR, SCI+nOFS+ATR, SCI+OFS). …”
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Integrative bulk RNA analysis unveils immune evasion mechanisms and predictive biomarkers of osimertinib resistance in non-small cell lung cancer
Published 2025-08-01“…Batch effect analysis highlighted a marked reduction in effector immune cells, such as activated CD8 + T cells, alongside an increase in immunosuppressive populations, emphasizing the role of immune evasion in osimertinib resistance.We constructed a robust diagnostic model, nomoScore, based on the hub genes, achieving excellent predictive accuracy (AUC > 0.9) in training and validation datasets. …”
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