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Suggested Topics within your search.
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Comparative analysis of the effectiveness of caudal epidural blocks and combined pharmacological therapy in the treatment of patients with discogenic low back pain
Published 2024-12-01“…Results. Assessment of the functional state after treatment showed that at the time of the final survey, after 6 months, positive changes with the absence of functional limitations were noted by 30 (83.3 %) patients with chronic nonspecific pain in the lumbar spine in the EB group and 8 (32 %) patients in the FT group. …”
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Enhanced optical properties of chitosan polymer doped with orange peel dye investigated via UV–Vis and FTIR analysis
Published 2025-01-01“…UV–Vis-NIR spectroscopy revealed significantly enhanced UV–visible light absorption in the 200–500 nm region and effective UV light blocking. FTIR analysis showed strong interactions between OPDs and the CS matrix, with functional groups such as O–H, C=O, and C=C. …”
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A Case Report of Clinical Features Analysis of a Novel IKBKG Variant Leading to Anhidrotic Ectodermal Dysplasia and Immunodeficiency
Published 2024-10-01“…In addition, genetic analysis is needed to exclude pseudogene interference and functional evaluations are required.…”
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Cyclin D2 – a potential biomarker in uterine corpus endometrial carcinoma through methylation chip and bioinformatic analysis
Published 2025-07-01“…CCND2 was selected for further functional analysis. IHC results revealed that the positive expression of CCND2 in UCEC was significantly lower than in normal endometrial tissue (P < 0.05). …”
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Comparative effectiveness of various orbital decompression techniques in treating thyroid-associated ophthalmopathy: a systematic review and meta-analysis
Published 2024-12-01“…Abstract Background In thyroid-associated ophthalmopathy (TAO), orbital decompression is a critical surgical approach for functional and aesthetic reasons. Meanwhile, the presence of surgical complications, especially the new onset of primary gaze diplopia, also influences postoperative patient satisfaction. …”
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Efficacy and safety of vitamin E as adjunctive therapy for epilepsy: a systematic review and meta-analysis of randomized control trials
Published 2025-07-01“…Vitamin E had a potential advantage in reducing seizure frequency by >75% (RR = 1.73, 95% confidence interval (CI) (1.31, 2.28), p < 0.01), compared with the control group. Subgroup analysis showed a statistically significant difference in the reduction of seizure frequency by >50% (RR = 1.58, 95% CI (1.27, 1.96), p < 0.01) between the vitamin E group and the control group, especially in children (RR = 1.69, 95% CI (1.29, 2.20), p < 0.01). …”
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Dapagliflozin combined with methylcobalamin in the treatment of type 2 diabetes mellitus with peripheral neuropathy: a systematic review and meta-analysis
Published 2025-06-01“…There was no significant increase in adverse events (OR: 0.37; 95% CI: 0.07–2.03; P=0.25).ConclusionDapagliflozin combined with methylcobalamin appears to be an effective and safe therapeutic strategy for managing DPN in T2DM patients, improving both nerve function and glycemic control.…”
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Outcomes of transcatheter aortic valve replacement in younger low-risk patients: a comprehensive meta-analysis of efficacy and safety
Published 2025-08-01“…Secondary endpoints included all-cause mortality, disabling stroke, atrial fibrillation (AF), permanent pacemaker implantation (PPI), bleeding, functional class (NYHA), and quality-of-life (KCCQ score) improvements.ResultsFour RCTs were included with 4,252 patients (2,125 TAVI and 2,127 SAVR). …”
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Association Between Estimated Pulse Wave Velocity and Endovascular Thrombectomy Outcome: A Secondary Analysis of the OPTIMAL‐BP Trial
Published 2025-05-01“…A reduction in ePWV at 24 hours after EVT increased the likelihood of functional independence at 3 months in patients receiving conventional BP management (adjusted odds ratio, 3.41 [95% CI, 1.02‒11.38]) but not in those receiving intensive BP management. …”
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Hierarchical Gaussian processes for characterizing gait variability in multiple sclerosis
Published 2025-01-01“…Reduction in mobility due to gait impairment is a critical consequence of diseases affecting the neuromusculoskeletal system, making detecting anomalies in a person’s gait a key area of interest. …”
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Efficacy of ginkgo biloba extract in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis of randomized controlled trials
Published 2025-03-01“…ObjectiveThis systematic review and meta-analysis aims to assess the efficacy of GBE in the treatment of IPF by evaluating its impact on total effective rate, blood gas analysis, pulmonary function tests, and markers of inflammation and fibrosis.MethodsWe conducted a comprehensive search across seven databases, including PubMed, EMBASE, Web of Science, CNKI, Wanfang DATA, VIP, and CBM, without restrictions on publication date. …”
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