Effects of ginger supplementation in individuals with mild to moderate joint pain I: ratings of pain, functional capacity, and markers of inflammation by Jacob Broeckel, Landry Estes, Megan Leonard, Broderick Dickerson, Drew E. Gonzalez, Martin Purpura, Ralf Jäger, Ryan Sowinski, Christopher J. Rasmussen, Richard B. Kreider

“…Data were analyzed using the general linear model (GLM) analysis of variance with repeated measures, mean changes from baseline with 95% confidence intervals, and chi-squared analysis.Results There was evidence that ginger supplementation: 1.) attenuated perceptions of muscle pain in the vastus medialis (Day 2: χ2 p = 0.087); 2.) reported less pain from sitting (Day 2: χ2 p = 0.02), while nocturnal pain (Day 32: χ2 p = 0.075, Day 58: (χ2 p = 0.097), weight bearing pain (Day 32: χ2 p = 0.058), physical functioning of performing heavy duties (Day 32: χ2 p = 0.100), and physical functioning of performing light duties (Day 2: χ2 p = 0.064) on WOMAC questions; 3.) experienced significant reductions in WOMAC overall ratings of pain, stiffness, physical function, and total score values, particularly in 48-hour follow-up measures; 4.) reported less pain during nighttime bed rest (Day 2: χ2 p = 0.065; Day 32: χ2 p = 0.032) and when going up and down stairs (Day 32: χ2 p = 0.097) from the LEQ; and, 5.) promoted significant differences over time and/or between groups in IL-β, IL-5, IL-6, IL-8, INF-γ, TNF-α, and high sensitivity C-reactive Protein at various points during the study.Conclusion Ginger supplementation promotes some favorable effects on exercise-induced perceptions of pain, functional capacity, and inflammatory markers in men and women who have mild to moderate muscle and joint pain.Registered clinical trial #ISRCTN74292348.…”
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Effect of processing methods on the nutrient, antinutrient, functional, and antioxidant properties of pigeon pea (Cajanus cajan (L.) Millsp.) flour by Abdulmajid Haji, Tilahun A. Teka, Tizazu Yirga Bereka, Tess Astatkie, Henock Woldemichael Woldemariam, Markos Makiso Urugo

“…All processing methods effectively reduced antinutritional components, with germination achieving the most substantial reductions in phytic acid and tannins. Functional properties were also affected: bulk density decreased across all methods, while water and oil absorption capacities increased, particularly in germinated flour. …”
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Diversity, functionality, and stability: shaping ecosystem multifunctionality in the successional sequences of alpine meadows and alpine steppes on the Qinghai-Tibet Plateau by Xin Jin, Abby Deng, Yuejun Fan, Kun Ma, Yangan Zhao, Yingcheng Wang, Kaifu Zheng, Xueli Zhou, Guangxin Lu

“…We further identify the primary environmental drivers of these changes and evaluate their collective impact on ecosystem multifunctionality. Our analysis reveals that, as vegetation communities progress from alpine meadows toward alpine steppes, multi-year average precipitation and temperature decline significantly, accompanied by reductions in soil nutrients. …”
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Determination of metallization degree of pre-reduced chromite with image and rietveld analysis by Leino T., Taskinen P., Eric R.H.

“…Metallization degrees for the investigated samples ranged from 15 to 65 % depending on the extent of reduction which was a function of time, reduction temperature, and methane content of the gas mixture. …”
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Outcome and safety 90 days after combined airway valve treatment of the right upper and middle lobes in patients with severe pulmonary emphysema by A. Susanne Dittrich, Cosimo Carlo De Pace, Judith Maria Brock, Franziska Trudzinski, Claus Peter Heussel, Ralf Eberhardt, Felix J. F. Herth, Konstantina Kontogianni

“…Abstract Background In COPD patients with severe right-sided emphysema, complete major and incomplete minor fissure, implantation of one-way valves in both the right upper (RUL) and middle lobes (ML) is a possible approach for endoscopic lung volume reduction. The aim of this retrospective analysis was to evaluate the response to therapy and the complication rate at 90 days (90d-FU) after combined RUL-ML valve implantation. …”
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ANALYSIS OF GENERAL PLOW BODY TRACTIVE RESISTANCE by A. Yu. Izmaylov, A. A. Artyushin, N. E. Evtyushenkov, G. S. Bisenov, V. F. Rozhin, D. N. Kynev

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SGRiT: Non-Negative Matrix Factorization via Subspace Graph Regularization and Riemannian-Based Trust Region Algorithm by Mohsen Nokhodchian, Mohammad Hossein Moattar, Mehrdad Jalali

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Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target by Chiara Piazzai, Alessio Petrone, Andrea Stefanini, Flavio D’Ascenzi, Iacopo Olivotto, Iacopo Olivotto, Matteo Cameli

“…Emerging therapies, like cardiac myosin inhibitors, also improve LV function but present complex effects on atrial performance, with some evidence suggesting a reduction in atrial strain that warrants further investigation.ConclusionAtrial remodelling is a significant marker of disease severity in HCM and an important independent predictor of adverse outcomes, including AF and cardioembolic events. …”
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Meta-analysis of nifedipine and enalapril combination therapy for hypertensive patients with coronary heart disease: A systematic review and meta-analysis by Kun Wang, Wenchao Ma, Leina Sun, Fangcheng Su

“…Additionally, the trial group exhibited a more pronounced reduction in blood pressure and greater enhancement in cardiac function (OR=5.55, 95%CI). …”
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Use the 4S (Signal-Safe Speckle Subtraction): Explainable Machine Learning Reveals the Giant Exoplanet AF Lep b in High-contrast Imaging Data from 2011 by Markus J. Bonse, Timothy D. Gebhard, Felix A. Dannert, Olivier Absil, Faustine Cantalloube, Valentin Christiaens, Gabriele Cugno, Emily O. Garvin, Jean Hayoz, Markus Kasper, Elisabeth Matthews, Bernhard Schölkopf, Sascha P. Quanz

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A randomised, double-blind clinical study into the effect of zinc citrate trihydrate toothpaste on oral plaque microbiome ecology and function by Suzi Elizabeth Adams, Andrew Kenneth Cawley, David Arnold, Michael John Hoptroff, Vera Slomka, Jane Reid Matheson, Robert Edward Marriott, Matthew Ronald Gemmell, Philip David Marsh

“…Increases at the species level were observed for taxa from the genus Veillonella with decrease in a taxon from the genus Fusobacterium for the zinc toothpaste. Analysis of microbiome function based on predicted metagenomic and metatranscriptomic analysis show that use of the zinc toothpaste is associated with an in-vivo reduction in glycolysis, consistent with the mode of action of zinc and, increases in processes linked to gum-health (lysine biosynthesis), and to whole-body health (nitrate reduction). …”
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Long-term surrogate cardiovascular outcomes of SGLT2 inhibitor empagliflozin in chronic heart failure: a systematic review and meta-analysis by Qingkai Yan, Xinrao Chen, Changqing Yu, Yuehui Yin

“…The meta-analysis revealed that EMPA administration significantly contributed to a reduction in systolic blood pressure (SBP) (MD = 4.93 mmHg, 95% CI=[-9.67, -0.19]; P < 0.0001) and left ventricular end-diastolic volume (LVEDV) (MD=-18.03 mL, 95% CI=[-25.4, -10.67], P < 0.0001). …”
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Research on the Performance Optimization of Turbulent Self-Noise Suppression and Sound Transmission of Acoustic Windows Made from Functionally Graded Material by Bing LI, Fu-Lin ZHOU, Jun FAN, Bin WANG, Liwen TAN

“…The STL, the turbulent self-noise reduction or a weighting function of the STL and turbulent self-noise reduction of FGM acoustic windows is chosen as the optimization objective. …”
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Investigating the association of microRNA polymorphisms and lifestyle factors with the susceptibility to common gastrointestinal cancers in an Indian population- A case control stu... by Charles Emmanuel Jebaraj Walter, Zioni Sangeetha Shankaran, Sai Sushmitha Kontham, Kotteeswaran Ramachandran, Nandini Prakash, Thanka Johnson, Sri Nisha JR

“…Multifactor dimensionality reduction analysis demonstrated that miRSNPs alter GI cancer risk by interacting with exposures like diabetes mellitus, alcohol consumption, diet and socioeconomic status in the study subjects. …”
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The Cr(VI) removal from tailing wastewater by magnetic amino-functionalized sludge biochar prepared through one-pot method by Zhiping Li, Yi Zhou, Quan Yin, Lidong Ma

“…Magnetic amino-functionalized sludge biochar (Fe@NBC) was prepared via a one-step method for efficient Cr(VI) removal from tailing wastewater. …”
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Comparative and synergistic impacts of lime and biochar on soil properties, nitrogen transformation, and microbial function in acidic soils under tobacco cropping by Bianhong Zhang, Lina Tang, Zhicheng Chen, Xiaoyan Chen, Lindong You, Ruixin Pan, Ting Chen, Yifei Liu, Wenxiong Lin, Wenxiong Lin, Jinwen Huang

“…Lime treatments (L, L+B) promoted nitrification potential in rhizosphere soil, whereas biochar application (B, L+B) resulted in elevated nitrate nitrogen content. Microbial functional analysis indicated that lime (L, L+B) enhanced nitrification, while biochar (B, L+B) fostered dissimilatory nitrate reduction, thereby improving nitrogen retention. …”
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Insights into the role of GhCYP and GhTPS in the gossypol biosynthesis pathway via a multiomics and functional-based approach in cotton by Teame Gereziher Mehari, Marijana Skorić, Hui Fang, Kai Wang, Fang Liu, Tesfay Araya, Branislav Šiler, Dengbing Yao, Baohua Wang

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SARS-CoV-2-induced cytokine storm drives prolonged testicular injury and functional impairment in mice that are mitigated by dexamethasone. by Stefanos Giannakopoulos, Jin Pak, Jackson Bakse, Monika A Ward, Vivek R Nerurkar, Michelle D Tallquist, Saguna Verma

“…This study characterized the consequences of SARS-CoV-2 on testis function. The K18-hACE2 mice that survived SARS-CoV-2 infection were followed for one month after infection and the testicular injury and function markers were assessed at different stages of infection and recovery. …”
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Lysozyme functionalized zinc-oxide nanoparticles: Synthesis, characterization, and antibacterial assessment against Staphylococcus aureus with futuristic application in wastewater... by Suneeti Singh, Pavni Rekhi, Jewel Mary Saju

“…In this context, the current study reports zinc oxide nanoparticles functionalized with lysozyme (ZnO@LY NPs) via a modified oxidation-reduction mechanism, followed by an assessment of their antibacterial activity. …”
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Water Use Enhancement and Root Function Compensatory Regulation of Biomass Accumulation in Quinoa Under Salt Stress by Photosynthetic Drive Advantage by Hao Xu, Lingzheng Feng, Jia Hao, Yongkun Zhang, Runjie Li

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