Multidimensional pain profiling in people living with obesity and attending weight management services: a protocol for a longitudinal cohort study by Catherine Blake, Carel W le Roux, Keith M Smart, Catherine M Doody, Francis M Finucane, Brona M Fullen, Jean O’Connell, Natasha S Hinwood, Colin Dunlevy, Clare Gilsenan, Grainne O'Donoghue

“…Obesity is associated with increased self-reported pain intensity and pain-related disability, reductions in physical functioning and poorer psychological well-being. …”
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DSG3 promotes bladder cancer growth and metastasis via AKT/GSK3β/β-catenin pathway by Tao Wang, Anqi Du, Yuan Peng, Jianjian Yin, Guoqiang Sun, Yihang Yu, Zhangran Sun, Qi Chang, Kaidi Gong, Shengna Han, Lirong Zhang, Dongkui Song

“…Importantly, elevated DSG3 levels demonstrated a strong association with aggressive tumor behavior and poorer clinical outcomes. Functional experiments revealed that DSG3 knockdown significantly impeded cancer stemness characteristics, epithelial-mesenchymal transition (EMT), migration, and invasion capabilities in vitro, whereas in vivo studies showed marked reductions in tumorigenesis and lung metastasis. …”
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Comprehensive rehabilitation of patients with early rheumatoid arthritis: results of 6-month program by Evgenia Vladislavovna Orlova, D E Karateev, A V Kochetkov

“…The outpatient and domiciliary stages included 45-min TE thrice weekly; creation of a correct functional stereotype; and orthotics. Twenty-six patients received medical therapy only (a control group). …”
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Overexpression of the GmERF071 gene confers resistance to soybean cyst nematode in soybean by Erhui Xiong, Jiaqi Xu, Pingzhang Feng, Yun Lian, Xiaoling Zhi, Ke Li, Erhan Zhang, Bing Li, Shijie Zhao, Changzhong Liu, Chengyu Wei, Panpan Li, Yaping Zhao, Lipei Zhao, Mengwei Zheng, Heng Zhang, Yi Li, Shanshan Chu, Yongqing Jiao

“…Abstract Soybean cyst nematode (SCN) is one of the most harmful pests, causing major reductions in soybean yield globally. The validation and functional characterization of SCN resistance genes are crucial to improving soybean yield worldwide. …”
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Evaluating oxide nanoparticle exsolution on A-site deficient PrBaCo2O6-δ electrodes by Alfonso J Carrillo, María Balaguer, Cecilia Solís, Andrés López-García, Sylvio Haas, María Fabuel, Blanca Delgado-Galicia, Isabelle Rodriguez, Einar Vøllestad, Sebastian Wachowski, Ragnar Strandbakke, Truls Norby, Jose M Serra

“…Combined Raman spectroscopy and electron microscopy analysis revealed that BaCoO _3 , Co _3 O _4 , and amorphous BaCO _3 nanoparticles were formed on the surface of the double perovskites after the reductive treatments. …”
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Rational design of sustainable thin-film composite membranes: Computational and experimental investigation of deep eutectic solvents as a green alternative to hexane for enhanced d... by Muhammad Akmal Rana, Farwah Hassan, Rahma Tamime, Palwasha Khan, Aqeel Ahmed Bazmi, Muhammad Yasin, Mazhar Amjad Gilani, Faheem Hassan Akhtar, Muhammad Aslam, Muhammad Bilal K. Niazi, Hamad AlMohamadi, Asim Laeeq Khan

“…Mass and solvent intensity analysis further highlighted the environmental benefits of DES, with reductions of 23 % and 26 % as compared to hexane, highlighting its resource efficiency. …”
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Size-dependent effects of oxo-degradable plastic contamination on soil quality and the growth of Zea mays by Do Thi Kim THANH, Robert W. BROWN, Martine GRAF, Michaela K. REAY, Charlotte E. M. LLOYD, Gupeng LI, David R. CHADWICK, Davey L. JONES

“…At extreme plastic loading rates (10% w/w), both micro- and macro-sized ODPs caused significant reductions in plant growth, with microplastic treatments having consistently greater effects than the macroplastic treatments. …”
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Clinical efficacy of modified laminoplasty in the treatment of cervical spondylotic myelopathy by Zhiyu Huang, Tianzuo Zhan, Shaodong Zhang

“…Methods A retrospective analysis was conducted on 93 patients who underwent laminoplasty for cervical spondylotic myelopathy (CSM) at our institution between January 2016 and June 2022. …”
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Implantable continuous-flow total artificial heart for newborns and small pediatric patients: First report of working modelCentral MessagePerspective by Jamshid H. Karimov, MD, PhD, Chihiro Miyagi, MD, PhD, Taiyo Kuroda, MD, Anthony R. Polakowski, BS, MEng, Christine R. Flick, BS, Barry D. Kuban, BS, Kiyotaka Fukamachi, MD, PhD, Tara Karamlou, MD, Munir Ahmad, MD, Hani Najm, MD

“…Results: The functional I-CFTAH prototype demonstrated capability to support stable hemodynamics and desired device performance. …”
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The interplay between epidermal barrier distribution, microbiota composition, and immune infiltrate defines and stratifies psoriasis patients and is associated with disease severit... by Elizabeth M. Ortega Rocha, Paul Hernández-Herrera, Sofia V. de los Santos- Carmona, Saraí G De León-Rodríguez, Ángel Juárez-Flores, Vadim Pérez-Koldenkova, Octavio Castro-Escamilla, Samira Muñoz-Cruz, Alicia Lemini-López, Laura C. Bonifaz

“…Our findings emphasize the complex interplay between epidermal barrier distribution, SEB localization, and functional CD4 TCRvβ17 cells in psoriatic skin, highlighting their potential in patient stratification in association with the severity of the disease.…”
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Effectiveness of a brief behavioural intervention on psychological distress among women with a history of gender-based violence in urban Kenya: A randomised clinical trial. by Richard A Bryant, Alison Schafer, Katie S Dawson, Dorothy Anjuri, Caroline Mulili, Lincoln Ndogoni, Phiona Koyiet, Marit Sijbrandij, Jeannette Ulate, Melissa Harper Shehadeh, Dusan Hadzi-Pavlovic, Mark van Ommeren

“…Between 15 April 2015 and 20 August 2015, 1,393 women were screened for eligibility on the basis of psychological distress and impaired functioning. Of these, 518 women (37%) screened positive, of whom 421 (81%) were women who had experienced GBV. …”
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Identification of Priority Areas for Ecological Restoration at a Small Watershed Scale: A Case Study in Dali Prefecture of Yunnan Province in China by Qiyuan Zhou, Qiuping Zhu, Yu Feng, Jinman Wang

“…Integrating ecological quality and risk levels, the study area was classified into four functional zones: Zone I (high quality, high risk), Zone II (low quality, high risk), Zone III (low quality, low risk), and Zone IV (high quality, low risk). …”
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Cognitive Training for Emotion-Related Impulsivity and Rumination: Protocol for a Pilot Randomized Waitlist-Controlled Trial by K J D Allen, Matthew V Elliott, Eivind Haga Ronold, Liam Mason, Nandini Rajgopal, Åsa Hammar, Sheri L Johnson

“…This pilot trial will gather preliminary evidence for a new cognitive training intervention targeting “hot” affective control (ie, inhibitory functions during elevated emotional arousal) in a transdiagnostic sample of adults who report heightened emotion dysregulation. …”
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Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility... by Gareth Ambler, Simon Dixon, Chris Brew-Graves, Norman R Williams, James W F Catto, John D Kelly, John McGrath, Melanie Tan, Muhammad Shamim Khan, Edward Rowe, Anthony Koupparis, Pramit Khetrapal, Rachael Sarpong, Andrew Feber, Louise Goodwin

“…Radical cystectomy (RC) with pelvic lymphadenectomy is a gold standard treatment for high-risk BC. Reductions in morbidity and mortality from RC may be achieved through robot-assisted RC (RARC). …”
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Dynamic Modeling of Convective Drying of Pineapple Peels: Bioactive, Physical, and Thermal Properties by Raniza de Oliveira Carvalho, Rossana Maria Feitosa de Figueirêdo, Alexandre José de Melo Queiroz, Francislaine Suelia dos Santos, Mailson Gonçalves Gregório, Lumara Tatiely Santos Amadeu, Henrique Valentim Moura, Nailton de Macedo Albuquerque Junior, Fabrícia Santos Andrade, Emily Bezerra Coutinho Cruz, Emerson Zambrano Lara, Josivanda Palmeira Gomes, Marta Suely Madruga

“…Thus, the study highlights pineapple peels as a promising raw material for producing nutrient-rich functional flour, with a drying temperature being a crucial factor in preserving bioactive compounds and achieving desirable product characteristics.…”
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Effects of Lacticaseibacillus paracasei K56 on perceived stress among pregraduate students: a double-blind, randomized, placebo-controlled trial by Yiran Guan, Ruixin Zhu, Wen Zhao, Langrun Wang, Li You, Zhaozhong Zeng, Qiuyue Jiang, Zeyang Zhu, Jiayu Gou, Qi Zhang, Jie Guo, Keji Li, Liang Zhao, Yixuan Li, Pengjie Wang, Bing Fang, Weilian Hung, Jian He, Liwei Zhang, Ran Wang, Jingjing He

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Effect of Biochar-Based Organic Fertilizer on the Growth of Maize in Cadmium-Contaminated Soil by Liyuan Mu, Hongyin Zhou, Ke Yang, Junlei Wang, Sijing Sun, Zhengli Lu, Lijuan Wang, Naiming Zhang, Li Bao

“…The T8 treatment (biochar-based organic fertilizer II at 3000 kg/ha) showed the best effect in reducing soil-available cadmium and cadmium content in corn grains, with reductions of 32.84% and 26.28%, respectively, compared to CK. …”
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Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…These systems offer real-time information updates, cost reductions for online space purchases, multilingual website accessibility, and diverse marketing strategy implementations. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
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Remote work – the new normal needs more research by Annina Ropponen

“…Wendsche J, Lohmann-Haislah A. A Meta-Analysis on Antecedents and Outcomes of Detachment from Work. …”
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