<i>Salmonella</i> Typhi-Exposed Placentae: Chorionic Villi Histomorphology and Neonatal Birthweight by Patience B. Tetteh-Quarcoo, Joana Twasam, Kevin Kofi Adutwum-Ofosu, John Ahenkorah, Bismarck Afedo Hottor, Nicholas T. K. D. Dayie, Peter Ofori Appiah, Emmanuel Afutu, Fleischer C. N. Kotey, Emilia Asuquo Udofia, Nii Koney-Kwaku Koney, Benjamin Arko-Boham, Eric S. Donkor

“…Aim: This study utilised stereology to assess histomorphological and functional alterations in term placentae of <i>Salmonella</i> Typhi-exposed placentae, compared to unexposed controls. …”
Get full text

IQUB mutation induces radial spoke 1 deficiency causing asthenozoospermia with normal sperm morphology in humans and mice by Tingwenyi Hu, Xiangrong Tang, Tiechao Ruan, Shunhua Long, Guicen Liu, Jing Ma, Xueqi Li, Ruoxuan Zhang, Guoning Huang, Ying Shen, Tingting Lin

“…To date, many components of RSs and their functions in human sperm flagella remain unclear. Methods We recruited a cohort of 323 infertile males with ASZ between August 2019 and June 2024. …”
Get full text

Cognitive impact and brain structural changes in long COVID patients: a cross-sectional MRI study two years post infection in a cohort from Argentina by Sol A. Cataldo, Andrea Micciulli, Laura Margulis, Melina Cibeyra, Sabrina Defeo, Silvina G. Horovitz, Analía Martino, Raul Melano, Milagros Mena, Francisco Parisi, Diego Santoro, Florencia Sarmiento, Martin A. Belzunce

“…Neuroimaging studies have identified structural alterations in brain regions linked to cognitive functions. However, most of these studies have focused on patients within months of their initial infection. …”
Get full text

Eco‑friendly biosynthesis of gold nanoparticles from Amphimedon compressa with antibacterial, antioxidant, anti-inflammatory, anti-biofilm, and insecticidal properties against dise... by Alsayed E. Mekky, Ebrahim Saied, Mahmoud M. Al-Habibi, Zeinab A. Shouaib, Ahmed I. Hasaballah, Mohammed E. Rashed, Ashjan F. Khaled, Amal Naif Alshammari, Fady Sayed Youssef, Ahmed M. Al-Shahat, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Mohammed Aufy, Tharwat A. Selim

“…FTIR spectroscopy indicated that secondary metabolites featuring –OH functional groups acted as reducing agents in the production of AuNPs. …”
Get full text

History and development direction of iterative upgrading of deep coalbed methane reservoir reconstruction technology：Taking the Daji Block in the eastern margin of the Ordos Basin... by Fengyin XU, Huaibin ZHEN, Shuguang LI, Feng WANG, Lei ZHANG, Yubin WANG, Weichu YU, Weiping ZHU, Borui XU, Yun YANG, Haifeng ZHAO, Kunsen BAI

“…Practical application of finely tailored fracturing designs based on geological characteristics has yielded remarkable results.However, the paper identifies five key challenges and areas for improvement in deep coal reservoir stimulation: High water consumption and difficulties in managing flowback fluids during ultra-large-scale fracturing; The need for breakthroughs in intelligent fracturing technologies; Immaturity of collaborative fracturing methods; The urgent requirement to establish fracturing technology systems for deep, medium-to-low-rank coal seams; Incomplete functionality of fracturing fluids.To address these challenges, six development directions are proposed:① Advancing water-reducing fracturing techniques; ② Conducting research on fishbone horizontal wells combined with matrix acidizing for large-scale water-reduction and production enhancement; ③ Expanding the application of artificial intelligence in intelligent fracturing and post-fracturing evaluation; ④ Developing and implementing collaborative fracturing techniques to optimize well-to-fracture network integration; ⑤ Strengthening research and development and application of stimulation technologies for deep, medium-to-low-rank coal reservoirs; ⑥ Innovating new fracturing materials to further reduce costs, improve efficiency, and enhance recovery rates for deep CBM.…”
Get full text

Hypoxic cancer-associated fibroblast exosomal circSTAT3 drives triple negative breast cancer stemness via miR-671-5p/NOTCH1 signaling by Lu Yang, Siyuan Zhao, Xu Liu, Yuchen Zhang, Shaorong Zhao, Xuan Fang, Jin Zhang

“…Exosomes were characterized via transmission electron microscopy (TEM), dynamic light scattering (DLS), and marker profiling (CD63⁺/TSG101⁺/Alix⁺, calnexin⁻). Functional effects of hypoxic CAF exosomes on TNBC cells (MDA-MB-231, SUM159) were assessed through proliferation/migration assays, stemness/epithelial-mesenchymal transition (EMT) marker analysis, and siRNA-mediated circSTAT3 knockdown. …”
Get full text

Novel pyrochlores in the Bi2O3–MgO–Ta2O5 (BMT) system: Synthesis optimisation, phase equilibria and dielectric properties by K.B. Tan, P.Y. Tan, Y. Feng, C.C. Khaw, V. Raman, H.C. Ananda Murthy, R. Balachandran, S.K. Chen, O.J. Lee, K.Y. Chan, D. Zhou, M. Lu

Get full text

Molecular Profiling, Characterization and Antimicrobial Efficacy of Silver Nanoparticles Synthesized from <em>Calvatia gigantea</em> and <em>Mycena leaiana</em> Against Multidrug-R... by Sayab Khan, Muhammad Fiaz, Iqbal Ahmad Alvi, Muhammad Ikram, Humaira Yasmin, Junaid Ahmad, Amin Ullah, Zeeshan Niaz, Shubana Hayat, Ajaz Ahmad, Prashant Kaushik, Arshad Farid

“…In addition, SEM results showed the cubic morphology of <i>C. gigantea</i> with a diameter of 65 nm, and the FTIR spectra of fruiting body revealed the presence of functional groups—carboxyl, nitro, and hydroxyl—in AgNPs, which catalyzed the reduction of Ag+ to Ag0. …”
Get full text

The spice clove effectively ameliorated hyperuricemia and hyperuricemia-induced kidney injury in mice by Fang Wang, Lin Fang, Jin-Juan Zhang, Qian Wang, Ya Wang, Qiong Fu, Yan Hong, Yan-Yan Gao, Xiao-Li Guo, Jing Li, Xue-Long Yan, Guo-Bo Xu, Xing-Jiang Liao, Xiang Fang, Shang-Gao Liao

Get full text

Macrophage is crucial for tongue development by regulating myogenesis and vascularization by Ziyao Wang, Mengqiao Wang, Jiani Liu, Delu Zhao, Jixiao Wang, Fulan Wei

“…Abstract Background Abnormal tongue development is a craniofacial deformity that affects dental-maxillofacial esthetics and function. Recent evidence has identified macrophages as multi-functional immune cells crucial for heart and brain development. …”
Get full text

A Ralstonia solanacearum effector regulates plant cell death by disrupting the homeostasis of the BPA1-ACD11 complex by Bingbing Xue, Yan Zhou, Yongxiao Xie, Xiaocheng Huang, Jinye Zhang, Yang Zhang, Wenyan Zhong, Jinjia Zhao, Dehong Zheng, Lifang Ruan

“…Our study reveals a novel mechanism by which an effector inhibits ETI and, for the first time, highlights the critical role of protein abundance in its function.IMPORTANCER. solanacearum infects major economic crops, notably tomato, potato, and tobacco, leading to substantial yield reductions and economic losses. …”
Get full text

Higher hemoglobin levels are associated with impaired left ventricular global strains in metabolic syndrome: a 3.0 T CMR feature tracking study by Xue Li, Shi-Qin Yu, Zhi-Gang Yang, Bi-Yue Hu, Ke Shi, Jing Wang, Xue-Ming Li, Ge Zhang, Wen-Rong Li, Rong Xu, Yuan Li

“…Methods A retrospective analysis included 254 patients with MetS and 78 sex-, age-, and Hb-matched controls. …”
Get full text

Prediction of Soil Carbon Sequestration in Rangelands Regarding the Depth and Elevation of Sample Locations using Adaptive Neuro-Fuzzy Inference System (ANFIS) (Case Study: Lar Wat... by zeinab jafarian, zhila ghorbani

“…This system is based on the combination of three components: membership functions of input and output variables (fuzzification), fuzzy rules (rule base), mechanism inference (a combination of rules with fuzzy input), output characteristics, and results of the system (de-fuzzification). …”
Get full text

Circ‐myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super‐Enhancers in FOSL2 Expression by Jingya Zhang, Xinru Wang, Xu Wang, Songyue Li, Jianli Hou, Yibin Zhang, Xinyue Song, Shukun Cao, Ya Xu, Jing Qi, Baoshan Zhao, Xiaodong Zheng, Yan Xing

“…CRISPR‐Cas9‐mediated knockdown of the FOSL2 SE resulted in a reduction in PANoptosis in PASMCs. Additionally, ChIP‐polymerase chain reaction assays revealed that FOSL2 functions as a transcription factor that binds to the promoters of PANoptosis‐related genes. …”
Get full text

Single-stage surgery with antibiotic-loaded hydrogel-coated implants versus two-stage surgery for chronic periprosthetic hip joint infection in French tertiary referral hospitals:... by Elisabeth Botelho-Nevers, Emilie Presles, Anne Carricajo, Céline Chapelle, Bertrand Boyer, Celine Cazorla, Carine Labruyere, Paul Zufferey

“…The single-stage procedure is thought to be less susceptible to late functional complications with a shorter, single hospital stay. …”
Get full text

Differential Effects of Hazardous Drinking on Post-Traumatic Stress Disorder Outcomes Across Two Prolonged Exposure Treatment Formats by Casey L. Straud, Kiara H. Buccellato, Edna B. Foa, Lily A. Brown, Carmen P. McLean, Tabatha H. Blount, Richard P. Schobitz, Bryann B. DeBeer, Joseph Mignogna, Brooke A. Fina, Brittany N. Hall-Clark, Christian C. Schrader, Jeffrey S. Yarvis, Vanessa M. Jacoby, Wyatt R. Evans, Brett T. Litz, Eric C. Meyer, Barbara L. Niles, Stacey Young-McCaughan, Terence M. Keane, Alan L. Peterson

“…The present study is an exploratory, secondary analysis investigating differential effects of prolonged exposure (PE) among those with and without hazardous drinking and whether treatment outcomes varied across these groups as a function of PE format. …”
Get full text

KArAT (Knee Arthroplasty Activity Trial): Rationale and design features of a multicenter randomized controlled trial by Elena Losina, Jamie E. Collins, Mahima Kumara, Linda Ehrlich-Jones, Maame Opare-Addo, Clare Safran-Norton, Neil A. Segal, Lauren M. Mitchell, Paul T. Kopp, Faith Selzer, Hanna Mass, Michael Paskewicz, Rowland W. Chang, Dorothy Dunlop, Antonia F. Chen, Samuel Lerner, Samantha Chin, Christine Pellegrini, Jeffrey N. Katz

“…Despite substantial pain reduction and functional improvements, physical activity (PA) does not necessarily increase post TKA. …”
Get full text

Perturbations in gut microbiota in autism spectrum disorder: a systematic review by Xiangkun Tao, Zhuocan Li, Dongfang Wang, Dongfang Wang, Dongfang Wang, Juncai Pu, Juncai Pu, Yiyun Liu, Yiyun Liu, Yiyun Liu, Siwen Gui, Siwen Gui, Siwen Gui, Xiaogang Zhong, Xiaogang Zhong, Xiaogang Zhong, Dan Yang, Haipeng Zhou, Wei Tao, Weiyi Chen, Xiaopeng Chen, Yue Chen, Xiang Chen, Peng Xie, Peng Xie, Peng Xie

“…These findings suggest that the disrupted intestinal microecology and functional changes in ASD are characterized by an enrichment of pro-inflammatory genera, a reduction of specific probiotics, lactic acid-producing and utilizing bacteria, and an imbalance of anti-inflammatory butyrate-producing bacteria. …”
Get full text

OGLE-2011-BLG-0462: An Isolated Stellar-mass Black Hole Confirmed Using New HST Astrometry and Updated Photometry by Kailash C. Sahu, Jay Anderson, Stefano Casertano, Howard E. Bond, Martin Dominik, Annalisa Calamida, Andrea Bellini, Thomas M. Brown, Henry C. Ferguson, Marina Rejkuba

“…\limits^{^{\prime\prime} }4$ from a bright neighbor, making it crucial to perform precise subtraction of its point-spread function (PSF) in the astrometric measurements of the source. …”
Get full text

Predicting dupilumab effectiveness with Type-2 biomarkers: A real-world study of severe asthma by Kenji Mizumura, Yasuhiro Gon, Norihiro Harada, Shiho Yamada, Asami Fukuda, Ryosuke Ozoe, Shuichiro Maruoka, Sumiko Abe, Kazuhisa Takahashi, Akihiko Tanaka, Hironori Sagara, Taisuke Akamatsu, Toshihiro Shirai, Katsunori Masaki, Koichi Fukunaga, Konomi Kobayashi, Hiroyuki Nagase, Nobuaki Miyahara, Arihiko Kanehiro, Noboru Kitamura, Naruhiko Sugihara, Fumio Kumasawa, Junko Terada-Hirashima, Masayuki Hojo, Kazuyuki Chibana, Etsuko Tagaya

“…Exacerbations and respiratory functions were monitored for 24 weeks. Asthma control was evaluated using the Asthma Control Questionnaire-5. …”
Get full text