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3481
Utilization of Artificial Intelligence Coupled with a High-Throughput, High-Content Platform in the Exploration of Neurodevelopmental Toxicity of Individual and Combined PFAS
Published 2025-02-01“…This study selected eleven PFAS commonly found in drinking water and exposed Caenorhabditis elegans to concentrations ranging from 0.1 to 200 µM to assess neurodevelopmental toxicity using a high-throughput, high-content screening (HTS) platform coupled with artificial intelligence for image analysis. Our findings showed that PFAS such as 6:2 FTS, HFPO-DA, PFBA, PFBS, PFHxA, and PFOS inhibited dopaminergic neuron activity, with fluorescence intensity reductions observed across concentrations from 0.1 to 100 µM. …”
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3482
Physiological aspects and production of coriander using nutrient solutions prepared in different brackish waters
Published 2022-08-01“…ABSTRACT The analysis of chlorophyll fluorescence is one of many ways to quantify the salt damage to photosynthetic performance and crop production. …”
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3483
Traffic safety evaluation of emerging mixed traffic flow at freeway merging area considering driving behavior
Published 2025-03-01“…First, human drivers’ driving behaviors were classified into aggressive driving, normal driving, and conservative driving using a k-means clustering algorithm based on field dataset analysis. Next, an improved lane-changing model of HDVs, accounting for driving behavior, was developed by incorporating lane-changing duration and a lane-changing motivation function within a multi-objective optimization framework. …”
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3484
Physical activity and cardiovascular risk in obese older Korean women: effects on obesity, hypertension, and arterial stiffness
Published 2025-06-01“…Further research is warranted to explore the effects of various intensities and types of PA on vascular health and metabolic function.…”
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3485
Comparing the Effectiveness of Surgical versus Medical Approaches in Managing Patients with Indeterminate Spinal Instability Neoplastic Scores
Published 2024-11-01“…The outcomes analyzed were patients’ functional status, complications, and conversion to surgery/revision surgery. …”
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3486
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3487
S-nitrosylation of EZH2 alters PRC2 assembly, methyltransferase activity, and EZH2 stability to maintain endothelial homeostasis
Published 2025-04-01“…Herein, we report S-nitrosylation of selected cysteine residues of EZH2 in endothelial cells, which interplays with its stability and functions. We detect a significant reduction in H3K27me3 upon S-nitrosylation of EZH2 as contributed by the early dissociation of SUZ12 from the PRC2. …”
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3488
Metabolomics and proteomics insights into hepatic responses of weaned piglets to dietary Spirulina inclusion and lysozyme supplementation
Published 2024-11-01“…Proteomics analysis identified 2,560 proteins, with 132, 11, and 52 differentially expressed in the Control vs. …”
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3489
Optimization by Hydrogen Plasma Treatment of a-CH and Hydrogen/Nitrogen-Assisted a-CH Layers for SAW Sensors
Published 2024-09-01“…X-ray photoelectron spectroscopy (XPS) studies indicated the formation of new functional groups, increased defect density, and a significant reduction in electron transitions following hydrogen plasma treatment. …”
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3490
Correlation of Intraoperative Neuromonitoring (IONM) Signal Changes with Clinical Outcomes in Patients with Compressive Cervical Myelopathy: A Prospective Study
Published 2025-01-01“…Paired t-tests were used for the comparison of preoperative and postoperative functional scores. One-way Analysis of variance (ANOVA) tests with Bonferroni post hoc analyses were performed for comparison between the three groups. …”
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3492
PHONETIC REHABILITATION FOR REMOVABLE DENTAL PROSTHETICS
Published 2019-06-01“… Removable prosthesis is considered as a device with therapeutic, rehab and prophylactic functions, which allows to improve the quality of life of the dentist. …”
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3493
Effects of Roasting on Antibacterial and Antioxidant Properties of <i>Sophora japonica</i> Buds—The Involvements of Rutin and Quercetin Constituents
Published 2024-11-01“…The results showed that dark yellow-roasted SJ buds exerted the strongest antibacterial and antioxidant activities and were also the richest in polyphenol contents. Analysis of rutin and quercetin revealed that, following the increment in heating temperatures up to 240 °C, the reduction in rutin content occurred in a parallel manner to the increment in quercetin content. …”
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3494
Sestrin2 alleviates cognitive impairment via inhibiting hippocampus ferroptosis in cigarette smoke-induced chronic obstructive pulmonary disease
Published 2025-09-01“…Our clinical data revealed a significant reduction in total hippocampal volume in patients with COPD, with the CA1 subfield notably smaller and associated with lung function. …”
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3495
Elevated SLC4A11 expression promotes OV progression via interaction with EGFR
Published 2025-07-01“…This study focused on Solute Carrier Family 4 Member 11 (SLC4A11), a gene highly expressed in OV, to explore its functional role and underlying mechanisms. Analysis of public datasets (TCGA and GEO) revealed that SLC4A11 expression was significantly elevated in OV tissues compared to normal tissues and was associated with poorer overall survival and advanced clinical stages. …”
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3496
Circular economy and 3D printing in the healthcare sector
Published 2025-03-01“…However, there remains a notable gap in the integration of circular economy principles to recycle plastic waste into functional, high-quality 3D printing filaments, particularly in clinical settings. …”
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3497
Research advances in the molecular regulatory mechanisms of fruit coloration in fruit trees
Published 2025-08-01“…Besides their coloring function, they also have photoprotective, antioxidant, and plant hormone precursor (ABA) synthesis functions. …”
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3498
“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration
Published 2024-10-01“…“CellChat” package facilitated the analysis of cell-cell communication. Differential gene expression analysis, PPI network, GO and KEGG pathway enrichment analysis, GSVA, co-expressed gene analysis and key gene-related networks were also performed to explore hub genes and their associated functions. …”
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3499
TGF-β/Smad2/3 signaling directly regulates several miRNAs in mouse ES cells and early embryos.
Published 2013-01-01“…Treatment of embryos with TGF-β inhibitor caused a reduction of their levels confirming that they are targets of this pathway in vivo. …”
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3500
Assessment of the adaptogenic properties of herbal tea based on pine needles and microstrobiles
Published 2025-04-01“…Morphometric studies showed that after administration of azathioprine significant morphofunctional changes were observed in the thymus and spleen of mice, which suggested a decreased functional activity of the organs. A decrease in the number and size of thymic Hassal’s bodies and a reduction of nucleated cells were observed in the thymus, while a significant two-fold decrease in the average area of follicles and a decrease in thickness of germinal centers were noticed in the spleen compared to those in the intact group. …”
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