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3221
Markers of intracellular energy supply under conditions of hypoxia in premature babies
Published 2024-10-01“…The well-being of the intrauterine environment and birth, morphological and functional maturity at birth are the basis for the child’s postnatal adaptation. …”
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3222
A Chimeric Peptide Derived from a Bacterial Effector Protein Attenuates TLR-2/4-Mediated Production of Pro-Inflammatory Cytokines and Enhances the Cellular Availability of Gentamic...
Published 2025-08-01“…A chimeric peptide, TB4-BBL2, was then generated and evaluated for cellular uptake, interaction with TLR adaptors, and functional activities. Binding of FAM-labelled TB4-BBL2 to FLAG-tagged TIRAP/MYD88 was confirmed via co-immunoprecipitation and fluorescence analysis, while degradation of adaptors was assessed by Western blotting. …”
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3223
Assessment of cardiovascular risk from the use of an interleukin-1 inhibitor in patients with severe tophaceous gout
Published 2016-03-01“…It is suggested that interleukin (IL)-1β inhibition may promote a reduction in the risk of cardiovascular diseases; however, the mechanism of this impact has not been adequately investigated.Objective: to evaluate the impact of canakinumab therapy on the structural and functional properties of the vascular bed and the stiffness of the vessel wall.Patients and methods. …”
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3224
Mesoporous hydrochar from Acacia falcata leaves by hydrothermal process for hexavalent chromium adsorption
Published 2025-04-01“…Material characterization indicated that the adsorbent has a rough and porous structure. FTIR analysis confirmed Cr(VI) adsorption through functional group interactions, evidenced by peak intensity changes and the emergence of a Cr–O bond vibration at 669 cm-1. …”
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3225
Concept and Methodological Aspects of Providing Balanced Innovative Development of Transportation System of the Russian Federation
Published 2020-04-01“…The transportation system is the most important strategic link of social and economic development of the country, one of the most dynamic, multiplicative and promising segments of the market, which makes 12.5 % of the gross domestic product (GDP) of the Russian Federation. An analysis of transport activity has demonstrated a smoldering recession over the last years which is accompanied by reduction of values for the most important resulting indicators. …”
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3226
Traction splinting (EAVAST protocol) versus operative fixation of proximal phalanx fractures: a comparative study of patient outcomes
Published 2022-03-01“…However, closed methods of reduction are increasing. This study aimed to compare functional outcomes for a non-operative cohort using a skin traction method developed by the Nepean Hospital, Sydney, Australia, termed ‘early active vector adjustable skin traction’ or EAVAST, compared to operatively managed patients. …”
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3227
EFFECT OF INFLIXIMAB ON PARAMETERS OF REMODELING OF ARTERIAL BLOODSTREAM, RANKL AND OSTEOPROTEGERIN LEVELS IN PATIENTS WITH RHEUMATOID ARTHRITIS
Published 2014-02-01“…To study the effect of infliximab (INF) on serum levels of RANKL and osteoprotegerin (OPG), as well as on structural and functional properties of the vascular wall in patients with rheumatoid arthritis (RA).Material and Methods. …”
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3228
Reduced Graphene Oxide-Coated Iridium Oxide as a Catalyst for the Oxygen Evolution Reaction in Alkaline Water Electrolysis
Published 2025-05-01“…This work introduces an innovative and eco-friendly strategy for constructing a high-performance, functionalized Ir-based catalyst.…”
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3229
Grammar-Based Computational Framework for Predicting Pseudoknots of K-Type and M-Type in RNA Secondary Structures
Published 2024-10-01“…A particularly challenging aspect of RNA analysis is the prediction of its secondary structure, which is crucial for elucidating its functional role in biological systems. …”
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3230
Hardware and software complex for operational management of a flexible site of highly efficient assembly production
Published 2025-05-01“…The created hardware and software complex, based on a script written in the Python3 language, combined the functionality necessary for the flexible production modules transport service algorithm study, the analysis of the network model for flexible automated production site functioning equipment, and organisation of flexible automated production site operational management subsystems. …”
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3231
AGE- MACULAR DEGENERATION AND GLAUCOMA. EPIDEMIOLOGICAL AND CLINIC-PATHOGENETIC ASPECTS
Published 2019-02-01“…However, it requires careful monitoring of dynamics of the visual-functional and structural changes of the retina and optic nerve, as well as timely therapy correction. …”
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3232
Strategic model for integrating biogas a framework for sustainable energy integration in agro-industries
Published 2024-12-01“…In this study, the technique of the system in functional analysis is shown systematically to translate various energy requirements in the factory as criteria for performance and functional design to be integrated, optimized, and energy efficient. …”
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3233
MaMsb2, a signaling mucin, is involved in conidiation, stress tolerances, and virulence in the entomopathogenic fungus Metarhizium acridum
Published 2025-12-01“…The signalling mucin gene Msb2 contributes to the modulation of fungal development and virulence, yet its functions have remained unexplored in entomopathogenic fungi. …”
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3234
Abstract 194: Impact of Pre‐treatment Cerebral Microbleeds on the Outcomes of Endovascular Thrombectomy
Published 2023-11-01“…We conducted this meta‐analysis to investigate the effect of cerebral microbleeds (CMBs) on the functional and safety outcomes of EVT in patients with AIS caused by LVO. …”
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3235
Resveratrol-Enhanced Human Neural Stem Cell-Derived Exosomes Mitigate MPP+-Induced Neurotoxicity Through Activation of AMPK and Nrf2 Pathways and Inhibition of the NLRP3 Inflammaso...
Published 2025-02-01“…The findings also demonstrated the increased expression of essential genes involved in mitochondrial biogenesis, such as PGC1α, NRF1, and Tfam, indicating improved mitochondrial function in the presence of RES-hNSCs-Exos. Further analysis revealed that these protective effects were mediated by activating the AMP-activated protein kinase (AMPK) and Nrf2 signaling pathways, which promoted mitochondrial health and reduced oxidative stress. …”
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3236
Unique transcriptomic response to sepsis is observed among patients of different age groups.
Published 2017-01-01“…To understand the human age-specific transcriptomic response to sepsis, a multi-cohort, pooled analysis was conducted on adults, children, infants, and neonates with and without sepsis. …”
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3237
Diversity of clustered protocadherin-α genes in neuronal identity and its role in short-term specific associative memory formation
Published 2025-06-01“…Furthermore, a comprehensive analysis of neural activity during memory recall in 2 h short-term memory and 24 h long-term memory following showed significant reductions in the hippocampus, amygdala, and retrosplenial cortex during short-term memory tasks. …”
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3238
Astrocytic glucocorticoid receptors in the ventral hippocampus modulate anxiety-like behaviors
Published 2025-10-01“…Consistent with this finding, chronic corticosterone administration was found to induce anxiety-like behaviors in mice, accompanied by a significant reduction in the GR expression in the vHPC. The GR reduction, while prominent and functionally significant in astrocytes, is not exclusive to them in the vHPC under these stress conditions. …”
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3239
Effect of LED spectrum on the regulation of appetite-related hormones in the digestive tract of red seabream (Pagrus major)
Published 2025-05-01“…IHC analysis revealed that PP was strongly expressed in the red and white groups, while weakly expressed in the green and blue groups. …”
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3240