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3161
Organ-on-a-Chip Models—New Possibilities in Experimental Science and Disease Modeling
Published 2024-12-01“…By consolidating multicellular structures, tissue–tissue interfaces, and physicochemical microenvironments, these microchips can replicate key organ functions. They also enable the high-resolution, real-time imaging and analysis of the biochemical, genetic, and metabolic activities of living cells in the functional tissue and organ contexts. …”
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3162
Individual Pharmacotherapy Management (IPM-II) for Patient and Drug Safety in Polypharmacy via Clinical Electronic Health Record Is Associated with Significant Fall Prevention
Published 2024-11-01“…IPM was associated with a significant reduction in in-hospital falls from 18 (9%) in CG to 3 (1.5%) in IG, a number needed to treat of 14, relative risk reduction 83%, OR 0.17 [95% CI 0.04; 0.76], <i>p =</i> 0.021 in multivariable regression analysis. …”
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3163
B cell c-Maf signaling promotes tumor progression in animal models of pancreatic cancer and melanoma
Published 2024-11-01“…RNA-seq analysis of isolated B cells revealed that B cell c-Maf signaling modulates immunoglobulin-associated genes and tumor-specific Ab production. …”
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3164
Long-term Results of Treatment of Patients with Non-proliferative Diabetic Retinopathy Angioprotectors
Published 2017-03-01“…We take into account the compensation of diabetes on the level of glycated hemoglobin (HbA1C) blood.Results: When monitoring patients with type 2 diabetes to optimize the treatment of established efficacy and safety of drug therapy Doxi-Hem® in the prevention and treatment of pre-clinical and early manifestations of DR (DR0, DR1), which is confirmed by reliable positive dynamics of visual functions (BCVA, p <0.05, before treatment 0,8±0,02, after treatment increased to 0,92±0,02), morphological reduction in retinal thickness (PZT, p <0.05; before treatment 272,3±5,8 mm, after treatment 241.5±15.8 um), increased sensitivity of the macula (CM, p <0.05, before treatment 22.2±1.5 dB, after treatment 27.0±3.2 dB). …”
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3165
Obesity drives depot-specific vascular remodeling in male white adipose tissue
Published 2025-06-01“…Additionally, we detect this fenestrated EC subtype in male human WAT, which undergoes reduction in individuals with obesity. Collectively, this atlas serves as a valuable tool for future studies to decipher the functional significance of different WAT EC subtypes.…”
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3166
CITED2 Binding to EP300 Regulates Human Spermatogonial Stem Cell Proliferation and Survival Through HSPA6
Published 2025-01-01“…These findings provide novel insights into the regulatory and functional mechanisms of CITED2-mediated hSSC development.…”
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3167
The Impact of Parental Support on Adherence to Therapist-Assisted Internet-Delivered Acceptance and Commitment Therapy in Primary Care for Adolescents With Anxiety: Naturalistic 12...
Published 2025-01-01“…Nevertheless, no differences in overall functioning measured by the Children’s Global Assessment Scale were found. …”
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3168
The peculiarities of changes in myocardial electrical activity and heart rate variability in patients with coronary artery disease depending on the stage of concomitant iron defici...
Published 2023-12-01“…There were no statistically significant correlations between indicators of iron metabolism and HRV in patients with CAD and functional ID. Conclusions. The decrease in iron stores in the body due to its tissue and transport reserves is accompanied by changes in the myocardial electrical activity, a progressive reduction in heart rate variability, autonomic dysfunction towards a suppression of the parasympathetic domain activity, confirming the relevant correlations with the ferrokinetic parameters. …”
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3169
Evaluation of the effectiveness of rehabilitation for diabetic foot syndrome
Published 2023-04-01“…An assessment of the quality of life indicators in diabetic patients with diabetic foot syndrome after using different treatment schemes has confirmed the effectiveness of the new method based on the obtained significant difference between the studied indicators in the MG and CG according to the Mann-Whitney criterion (Р ˂ 0.05) with regard to the following components: physical functioning, role functioning, pain, general health, and emotional functioning. …”
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3170
Design of a Convolutional Neural Network with Type-2 Fuzzy-Based Pooling for Vehicle Recognition
Published 2024-12-01“…This innovative pooling method utilizes type-2 fuzzy membership functions to effectively manage local imprecision in feature maps. …”
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3171
An Improved Spatio-Temporal Network Traffic Flow Prediction Method Based on Impedance Matrix
Published 2024-06-01“…The Impedance-STTN model integrates K-medoids clustering for data analysis, generating a real-time impedance matrix from impedance functions, traffic big data, and real-time flow data. …”
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3172
Construction of a tumor mutational burden-derived LncRNA prognostic computational framework associated with therapy sensitivity in skin cutaneous melanoma
Published 2024-10-01“…Methods TILPI was developed using a combination of gene set variation analysis, differential expression analysis, and COX regression analysis. …”
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3173
The meaning of sport and physical activity from a youth perspective
Published 2025-02-01“…Methods: This study uses a qualitative phenomenological approach with data collection methods through in-depth interviews using purposive sampling with 18 informants aged 15-29 who are active in sports in Semarang City. Data analysis was conducted using the Miles and Huberman model, which includes data reduction, data presentation, and conclusion drawing. …”
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3174
Particle Size Optimization of Melinjo (Gnetum gnemon L.) Seed Hardshell: A Potential Antioxidant Alternative
Published 2024-08-01“…In this context, physical manipulation, specifically particle size reduction, is an effective strategy to address these issues. …”
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3175
Review article developing safety and enjoyment factors in karst cave tourism model: review discussing the model, factors and results
Published 2025-12-01“…The results obtained were 268 articles, then data reduction was carried out and 39 journals were obtained for review. …”
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3176
Particle Size Optimization of Melinjo (Gnetum gnemon L.) Seed Hardshell: A Potential Antioxidant Alternative
Published 2024-08-01“…In this context, physical manipulation, specifically particle size reduction, is an effective strategy to address these issues. …”
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3177
Migrating from Developing Asynchronous Multi-Threading Programs to Reactive Programs in Java
Published 2024-12-01“…The results are examined in terms of functional equivalence, testing, and comparative analysis of response times, resource utilization, and throughput, as well as the cases where the reactive paradigm proves to be a solution worth considering. …”
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3178
Peculiarities of lymphocytes emigration from newborn thymus
Published 2017-12-01“…The profound microscopic analysis of cell contents, lymphatic vessels morphology in morpho-functional areas of rats’ thymuses during the first week after birth in 4 hours interval was carried out. …”
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3179
Validation of an Eye-Tracking Algorithm Based on Smartphone Videos: A Pilot Study
Published 2025-06-01“…<b>Introduction:</b> This study aimed to develop and validate an efficient eye-tracking algorithm suitable for the analysis of images captured in the visible-light spectrum using a smartphone camera. …”
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3180
THE USE OF SUBSTANDARD VOCABULARY AS TRANSGRESSIVE COMMUNICATIVE STRATEGY IN THE FIELD OF MODERN MASS MEDIA
Published 2021-09-01“…The focus of this work is on comprehension of active process in the modern Russian language: changes in lexis and grammar, widening of stylistic variability and social functioning of the language, formation of a particular communicative area, which has a virtual status, and new strategies of speech behavior. …”
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