High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats by José Mário Matos-Sousa, Deiweson Souza-Monteiro, Vinicius Ruan Neves dos Santos, Maria Karolina Martins Ferreira, Deborah Ribeiro Frazão, Victória Santos Chemelo, Leonardo de Oliveira Bittencourt, João Daniel Mendonça de Moura, Cristiane do Socorro Ferraz Maia, Fabrício Mezzomo Collares, Luanna de Melo Pereira Fernandes, Rafael Rodrigues Lima

Get full text

COMPARATIVE ASSESSMENT OF RESPIRATORY MUSCLE STRENGTH IN THOSE WITH ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND COMBINATION OF THESE TWO CONDITIONS by B. I. Geltser, K. I. Shakhgeldyan, I. G. Kurpatov, V. N. Kotelnikov

“…Dysfunction of expiratory muscle dominated in asthma patients, while in COPD patients and those with both conditions it was diaphragm dysfunction. The correlation analysis demonstrated the dependence of respiratory muscle strength on the intensity of bronchial obstruction and lung hyperinflation, skeletal muscles mass, body mass index, respiratory discomfort, and functional state of the patients. …”
Get full text

Reduced graphene oxide-based absorbance biosensors for detecting Escherichia coli DNA by Chau Nguyen Minh Hoang, Son Hai Nguyen, Mai Thi Tran

“…This study presents a reduced graphene oxide-based biosensor for the sensitive and specific detection of E. coli DNA. The functionalized reduced graphene oxide was successfully synthesized using a modified Hummers’ method, followed by a hydrothermal reduction step. …”
Get full text

Mutations in hnRNP A1 drive neurodegeneration and alternative RNA splicing of neuronal gene targets by Ansalna Ansari, Patricia A. Thibault, Hannah E. Salapa, Joseph-Patrick W.E. Clarke, Michael C. Levin

“…RNA sequencing and differential alternative splicing analysis of mutant-expressing neurons revealed dramatic changes in alternative RNA splicing of transcripts critical to neuronal function. …”
Get full text

Long-term outcome of vagus nerve stimulation therapy in drug-resistant epilepsy: a retrospective single-center study by Si Chen, Xiaxin Yang, Shujun Xu, Baomin Li, Chao Li, Ning Yang, Xue Yang, Xiaotang Wang, Shuo Xu, Xiuhe Zhao, Xiuhe Zhao

Get full text

Extraction, Isolation, and TEMPO-NaBr-NaClO Oxidation Modification of Cellulose from Coffee Grounds by Mourad Ouhammou, Abdellah Mourak, Aziz Ait-Karra, Jaouad Abderrahim, Najat Elhadiri, Mostafa Mahrouz

“…The results indicate a reduction in crystallinity index from native cellulose (80%) to oxidized cellulose (65%), reflecting partial disruption of the microfibril structure and the introduction of new chemical functionalities. …”
Get full text

Soluble fibres modulate dough rheology and gluten structure via hydrogen bond density and Flory-Huggins water interaction parameter by Stefano Renzetti, Lisa Lambertini, Helene C.M. Mocking-Bode, Ruud G.M. van der Sman

“…Soluble fibres are gaining increasing interest for functional food applications like bread, but their interaction with gluten and effects on dough rheology are not fully elucidated. …”
Get full text

FORMAL REPRESENTATION OF THE PIXEL-BY-PIXEL CLASSIFICATION PROCESS USING A MODIFIED WANG-MENDEL NEURAL NETWORK by Oleksii Kolomiitsev, Volodymyr Pustovarov

“…The following tasks are solved in the article: analysis of possibilities of Wang-Mendel network modification based on representation of membership functions in terms of interval fuzzy sets of the second type (IFST2) and realization of phasing, aggregation and activation operations using IFST 2 operations, development of the architecture of the modified fuzzy neural production network of Wang-Mendel as a classifier for image segmentation. …”
Get full text

The number, status and organizational aspects of Serbs in Zagreb by Župarić-Iljić Drago

“…This paper provides an overview of the basic characteristics regarding number, as well as normative and functional status, i.e. legal and institutional status of Serbs in Zagreb. …”
Get full text

Stromal-vascular fraction of adipose tissue using in the repair of distal biceps tendon tears by M. S. Lisunov, M. L. Holovakha, M. O. Kozhemiaka

“…The using of SVF allowed the reduction of the recovery time and decreased in the incidence of complications, as well as improved functional outcomes. …”
Get full text

Impact of rhizosphere quantitative microbiome and soil properties on alkaloid levels in Lycoris aurea herb by Guang-hua Liu, Jianglin Li, Long-Xia Yan, Hong-Ping Deng, Miao-Hua Quan, You-Wei Zuo

“…Functional annotations of microbial taxa revealed differences in metabolic functions such as chitinolysis and nitrate reduction in the high alkaloid groups, respectively. …”
Get full text

Green synthesis of zinc oxide nanoparticles: A trifecta of antioxidant, antifungal, and catalytic excellence by Abraham Y. Danas, Ayomide H. Labulo, Abdullahi Usman, Ibrahim Hassan, Augustine D. Terna, Festus O. Ogungbemiro, David A. Oyinade, Ambo A. Idzi, Mojisola Owoseni, Maryam Isah, Rukayat A. Ashonibare, Kehinde A. Ojedola, Hafsat O. Dahiru, Zikhona Tywabi-Ngeva, Muhammad A. Said, Caroline A. Muaka

“…The synthesis of ZnONPs with distinct properties was successfully demonstrated by the structural and morphological investigations. The existence of functional groups involved in the stabilisation and reduction of the nanoparticles was established by FTIR. …”
Get full text

Biological Activity of Biomarkers Associated With Metastasis in Osteosarcoma Cell Lines by Nidia Ednita Beltrán‐Hernández, Luis Cardenas, Verónica Jimenez‐Jacinto, Leticia Vega‐Alvarado, Heriberto Manuel Rivera

“…Conclusions The gene functional enrichment analysis of DEGs enabled the identification of interaction networks in osteosarcoma, thereby revealing potential biomarkers. …”
Get full text

Integration of single-cell sequencing and drug sensitivity profiling reveals an 11-gene prognostic model for liver cancer by Qunfang Zhou, Jingqiang Wu, Jiaxin Bei, Zixuan Zhai, Xiuzhen Chen, Wei Liang, Jing Meng, Mingyu Liu

“…Functional analysis revealed that upregulated genes in high-risk groups were enriched in cell adhesion pathways, while downregulated genes were enriched in metabolic pathways. …”
Get full text

Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…The results of this trial need to be interpreted with caution because it did not recruit the required number of participants to achieve intended statistical power; however, the estimates of the effect size of bisoprolol were close to unity and consideration of the CIs suggests that the ITT analysis narrowly failed to exclude a predefined clinically important ≥ 15% reduction in COPD exacerbations. …”
Get full text

Diffusion imaging changes in the treated tract following focused ultrasound thalamotomy for tremor by Erin L. Mazerolle, Robyn Warwaruk-Rogers, Paul Romo, Tejas Sankar, Sarah Scott, Conrad P. Rockel, Samuel Pichardo, Davide Martino, Zelma H.T. Kiss, G. Bruce Pike

“…No significant correlations were detected between diffusion measures and clinical effects, suggesting that microstructural changes in the treated portion of the DRTT alone do not fully explain tremor reduction and motivating additional research using higher spatial resolution diffusion imaging and multimodal approaches such as integrating diffusion and functional magnetic resonance imaging data. …”
Get full text

Cost efficiency of inpatient rehabilitation following acquired brain injury: the first international adaptation of the UK approach by Ian D Cameron, Julie Ratcliffe, Ian Cameron, Belinda Gabbe, Rachel Milte, Ciara Ryan, Karen Roberts, Zhibin Chen, Russell Gruen, Laura Jolliffe, Natasha A Lannin, Peter Hunter, Maria Crotty, Lynne Turner-Stokes, Lisa Cameron, David Attwood, Anne Holland, Jacqui Morarty, Lynne Turner Stokes, Christine Latimer, Dina Watterson, John Rabling, Melanie Reed, Mithu Palit, Troy Huggins, Verna Smith, Elizabeth O’Shannessy, Rebecca Nicks, Alison Gehrig, Katelyn Moloney, Sophie O’Keefe, Megan Coulter, Margaret Inches, Erin Gee, Sue McLellan

“…Objectives To adapt and apply a model for evaluating the functional benefits and cost efficiency of specialist inpatient rehabilitation to the Australian context, comparing functional outcomes and savings in the cost of ongoing care after acquired brain injury.Design An observational cohort analysis of prospectively collected clinical data from admission to discharge, with follow-up to 3 years.Setting A newly established state-wide inpatient postacute rehabilitation unit in Victoria, Australia for patients with moderate to severe acquired brain injury.Participants This study included consecutive patients admitted to the programme during its first 2 years’ operation (January 2016 to December 2017). …”
Get full text

Metagenome-assembled genomes provide insight into the microbial taxonomy and ecology of the Buhera soda pans, Zimbabwe. by Ngonidzashe Mangoma, Nerve Zhou, Thembekile Ncube

“…The MAGs were subjected to taxonomic placement, phylogenetic profiling and functional annotation in order to establish their possible ecological roles in the soda pan ecosystem. …”
Get full text

Computational investigation of Belzutifan drug delivery mechanisms using SiC nanocrystals via combined DFT and molecular dynamics approaches by Wael A. Mahdi, Adel Alhowyan, Ahmad J. Obaidullah

“…Electronic structure analysis reveals significant charge transfers (-0.25e) from Belzutifan to the nanocrystal, accompanied by a substantial reduction in the HOMO-LUMO gap from 5.427 eV (pristine SiC) to 3.41 eV (Belzutifan@SiC-COOH complex), indicating improved electronic coupling. …”
Get full text

THE EFFECTIVENESS OF MEDICAL REHABILITATION IN CORONARY HEART DISEASE AS A PART OF THE SPA RESORT TREATMENT by A. S. Ivashchenko, V. V. Iezhov, N. A. Severin, N. A. Prokopenko

“…Reliable positive trends were set for a number of domains: the sensation of pain and dizziness (b280 and b2401), blood pressure (b420), tolerance to physical exercises (b455), general metabolic functions (b540) and the sensations associated with the functioning of the cardiovascular and respiratory systems (b4601).Conclusions. …”
Get full text