Suggested Topics within your search.
Suggested Topics within your search.
-
3061
Differential expression of disulfide reductase enzymes in a free-living platyhelminth (Dugesia dorotocephala).
Published 2017-01-01“…Although It was not possible to discriminate DTNB reductase activity due to TrxR from that of TGR, a chromatofocusing experiment with a D. dorotocephala extract resulted in the obtention of a minor protein fraction enriched in TrxR, strongly suggesting its presence as a functional protein. Thus, unlike its parasitic counterparts, in the free-living platyhelminth lineage the three disulfide reductases are present as functional proteins, albeit TGR is still the major disulfide reductase involved in the reduction of both Trx and GSSG. …”
Get full text
Article -
3062
The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster.
Published 2010-03-01“…Through deletion of the C3G locus, we have observed that loss of C3G causes semi-lethality, and that escaping adult flies are characterized by a reduction in lifespan and general fitness. In situ hybridization reveals C3G expression in the developing embryonic somatic and visceral muscles, and indeed analysis of C3G mutants suggests essential functions of C3G for normal body wall muscle development during larval stages. …”
Get full text
Article -
3063
miRNA-29b-1-5p mediates an antiviral activity by targeting the HBV entry receptor in human hepatocytes
Published 2025-07-01“…Functional analysis indicated that miR-29b-1-5p directly targeted the NTCP 3ʹ-UTR, leading to significant inhibition of NTCP transcripts. …”
Get full text
Article -
3064
The Effect of the <i>swnR</i> Gene on Swainsonine Biosynthesis in <i>Alternaria oxytropis</i> OW7.8, an Endophytic Fungus of <i>Oxytropis glabra</i>
Published 2025-06-01“…Compared with <i>A. oxytropis</i> OW 7.8, the Δ<i>swnR</i> exhibited distinct morphological alterations in both colony and mycelial structure, a slower growth rate, and significant reductions in swainsonine (SW) levels, indicating that the function of the <i>swnR</i> gene promoted SW biosynthesis. …”
Get full text
Article -
3065
<i>In Vitro</i> Evaluation of the Microleakage in Bioflex Crowns Luted with Two Different Cements
Published 2025-04-01“…Results: RMGIC showed significantly lower microleakage compared to GIC, with a marked reduction in both the volume and area of leakage. Statistical analysis revealed a significant difference between the two cements, indicating that RMGIC provides a better seal and stronger bond between the crown and tooth. …”
Get full text
Article -
3066
Gastric Microbiota Associated with Gastric Precancerous Lesions in <i>Helicobacter pylori</i>-Negative Patients
Published 2025-01-01“…<i>Prevotella jejuni</i> and the genus <i>Parvimonas</i> were enriched in the IM group. A predictive functional analysis revealed enrichment of the ornithine degradation pathway in the IM and dysplasia groups, suggesting its role in persistent gastric mucosal inflammation associated with gastric precancerous lesions. …”
Get full text
Article -
3067
The smart city concept as a method of building urban resilience to threats: Evidence from Poland
Published 2025-07-01“…Objectives The functioning of cities is strongly influenced by local phenomena and global processes related to the urban natural environment. …”
Get full text
Article -
3068
IoT Integrated Graphene Derivative-Based Capacitive Sensors with Machine Learning Classification for Precision Soil Moisture Monitoring Process
Published 2025-01-01“…Principal Component Analysis (PCA) was employed for dimensionality reduction and was able to capture more than 92% and 95% of data variance for the GO and rGO sensors, respectively. …”
Get full text
Article -
3069
Application of legal enforcement measures for violation of financial legislation: problems of theory and practice
Published 2023-06-01“…The subject of the study is the legal norms that fix the procedure for applying coercive measures for violation of financial legislation, as well as doctrinal approaches and concepts on the chosen subject.The purpose of the article is: firstly, to rethink the leading role of the sectoral approach to the analysis and legal regulation of enforcement measures for violations of financial legislation, the development of which has led to the formation of alternative legal structures for regulating financial relations and parallel legal institutions of legal liability; secondly, in determining effective legal instruments aimed at streamlining the system of measures of state coercion applied to subjects of financial legal relations.The article examines: alternative, bypassing the current legislation, legal regulation of relations in the field of application of coercive measures; parallel legal institutions of legal responsibility for violation of financial legislation, as well as issues of streamlining the system of property sanctions for financial offenses.The use of general logical research methods, including analysis and synthesis, the formal legal and comparative legal methods, allowed the author to come to the following conclusions: (1) the emergence of alternative legal structures for regulating coercive measures for violation of financial legislation is caused by a mixture of state functions between federal executive authorities, the reason for which is a deviation from the concept of a three-tier system of public administration; (2) based on an industry approach, the well-established opinion of the legislator to determine the types of legal liability leads to the absence of conjugation of legislative acts in this area and, as a result, to the unreasonable application of legal liability measures, to double liability, as well as to problems in the field of determining the evidence base in cases of financial offenses; (3) as a basis for streamlining the system of coercive measures for violation of financial legislation, it is advisable to take an approach aimed at overcoming the gap between branches of law, the development of which is manifested in the expansion of the reception of universal legal structures in financial legislation and the application of the obligatory method of imposing property liability, which allows creating a different mechanism for imposing economic sanctions, corresponding to the riskbased approach to the implementation of control and supervisory activities. …”
Get full text
Article -
3070
Effect of occlusal interference on condylar position and trajectory of movement: a randomized crossover-controlled trial
Published 2025-04-01“…Mandibular movements were recorded and measured by using jaw motion analysis system, during which the condylar trajectory and functional parameters, including sagittal condylar inclination (SCI) and Bennett Angle (BA) were analyzed to assess the condylar motion status. …”
Get full text
Article -
3071
Photovoltaic and electrophysical properties of plasmon-enhanced organic solar cells
Published 2017-12-01“… A technique for depositing plasmon silver nanoparticles into various functional layers of an organic solar cell has been developed. …”
Get full text
Article -
3072
The Effect of an advanced nurse practitioner led menopause clinic on quality of life and menopausal symptoms
Published 2025-04-01“…The sample was randomly selected by identifying every second patient on a single medical surgery database. Statistical analysis was ascertained utilizing central tendency excel functionality. …”
Get full text
Article -
3073
DEHP-Induced Glioblastoma in Zebrafish Is Associated with Circadian Dysregulation of PER3
Published 2024-11-01“…Long-term exposure to DEHP can cause endocrine disruption and interfere with the organism’s normal functioning. In order to explore the potential effects of DEHP on the development of biological brain tissues, this study used bioinformatics analysis to confirm the diagnostic and prognostic value of PER3 in gliomas and further validated the neurotoxicity of DEHP using methods such as behavioral experiments and molecular biology in zebrafish. …”
Get full text
Article -
3074
Exploring the interplay of gender, breastfeeding practices, and minimum dietary diversity on stunting among Indonesian children aged 6–23 months
Published 2025-06-01“…Stunting requires a faster reduction in prevalence to avoid functional losses in children. …”
Get full text
Article -
3075
Impact of carbon emission trading on urban electricity efficiency
Published 2025-04-01“…[Objective] A thorough analysis of how the carbon emission trading system would affect the electricity efficiency of cities is of great significance for comprehensively assessing its economic effectiveness in energy conservation and emission reduction, and thereby promoting the realization of the “dual carbon” goals. …”
Get full text
Article -
3076
Bucket working bodies with conveyor bottom: systematics and design features
Published 2020-10-01“…Analysis of the bulk materials handling processes using existing loading appliances identified design flaws that affect the efficiency of their operation. …”
Get full text
Article -
3077
Targeted pancreatic cancer therapy using 4-farnesyloxycoumarin conjugated nanocrystalline cellulose and Chitosan nanoparticles
Published 2025-05-01“…Dynamic light scattering (DLS) analysis revealed a Z-average particle size of 275.68 nm, with a polydispersity index of 0.3020. …”
Get full text
Article -
3078
Untying the antimicrobial and antioxidant potential of silver nanoparticles fabricated from Typhonium trilobatum (L.) Schott
Published 2024-11-01“…The AgNPs were spherical with diameter ranges between 30 and 90 nm, negatively charged at −29.6 mV, crystalline in nature and surrounded by different active functional groups as evident by FTIR spectra analysis. …”
Get full text
Article -
3079
Influential Factors in the Realization of the Third Place in Informal and Sociable Urban Spaces (Case Study: Informal Sitting Spaces Inside Tehran's Cultural and Commercial Complex...
Published 2022-07-01“…Problem statement: The reduction of modern human living space, the obliteration of old neighborhoods and their centers, and the large-scale areas inherited from the modern time have reduced sustainable social interactions and the active presence of people in modern cities. …”
Get full text
Article -
3080