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  1. 3061

    Differential expression of disulfide reductase enzymes in a free-living platyhelminth (Dugesia dorotocephala). by Alberto Guevara-Flores, Álvaro Miguel Herrera-Juárez, José de Jesús Martínez-González, Irene Patricia Del Arenal Mena, Óscar Flores-Herrera, Juan Luis Rendón

    Published 2017-01-01
    “…Although It was not possible to discriminate DTNB reductase activity due to TrxR from that of TGR, a chromatofocusing experiment with a D. dorotocephala extract resulted in the obtention of a minor protein fraction enriched in TrxR, strongly suggesting its presence as a functional protein. Thus, unlike its parasitic counterparts, in the free-living platyhelminth lineage the three disulfide reductases are present as functional proteins, albeit TGR is still the major disulfide reductase involved in the reduction of both Trx and GSSG. …”
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  2. 3062

    The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster. by Margret Shirinian, Milica Popovic, Caroline Grabbe, Gaurav Varshney, Fredrik Hugosson, Hans Bos, Holger Rehmann, Ruth H Palmer

    Published 2010-03-01
    “…Through deletion of the C3G locus, we have observed that loss of C3G causes semi-lethality, and that escaping adult flies are characterized by a reduction in lifespan and general fitness. In situ hybridization reveals C3G expression in the developing embryonic somatic and visceral muscles, and indeed analysis of C3G mutants suggests essential functions of C3G for normal body wall muscle development during larval stages. …”
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  3. 3063

    miRNA-29b-1-5p mediates an antiviral activity by targeting the HBV entry receptor in human hepatocytes by Luc Gailhouste, Yutaka Furutani, Xian-Yang Qin, Shoko Higuchi, Mariko Toguchi, Kaori Yanaka, Koichi Watashi, Takaji Wakita, Soichi Kojima

    Published 2025-07-01
    “…Functional analysis indicated that miR-29b-1-5p directly targeted the NTCP 3ʹ-UTR, leading to significant inhibition of NTCP transcripts. …”
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  4. 3064

    The Effect of the <i>swnR</i> Gene on Swainsonine Biosynthesis in <i>Alternaria oxytropis</i> OW7.8, an Endophytic Fungus of <i>Oxytropis glabra</i> by Ning Ding, Chang Liu, Ping Lu, Lu Bai, Bo Yuan

    Published 2025-06-01
    “…Compared with <i>A. oxytropis</i> OW 7.8, the Δ<i>swnR</i> exhibited distinct morphological alterations in both colony and mycelial structure, a slower growth rate, and significant reductions in swainsonine (SW) levels, indicating that the function of the <i>swnR</i> gene promoted SW biosynthesis. …”
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  5. 3065

    <i>In Vitro</i> Evaluation of the Microleakage in Bioflex Crowns Luted with Two Different Cements by Harsh S Baldawa, Mahesh Ramakrishnan

    Published 2025-04-01
    “…Results: RMGIC showed significantly lower microleakage compared to GIC, with a marked reduction in both the volume and area of leakage. Statistical analysis revealed a significant difference between the two cements, indicating that RMGIC provides a better seal and stronger bond between the crown and tooth. …”
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  6. 3066

    Gastric Microbiota Associated with Gastric Precancerous Lesions in <i>Helicobacter pylori</i>-Negative Patients by Han-Na Kim, Min-Jeong Kim, Jonathan P. Jacobs, Hyo-Joon Yang

    Published 2025-01-01
    “…<i>Prevotella jejuni</i> and the genus <i>Parvimonas</i> were enriched in the IM group. A predictive functional analysis revealed enrichment of the ornithine degradation pathway in the IM and dysplasia groups, suggesting its role in persistent gastric mucosal inflammation associated with gastric precancerous lesions. …”
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  7. 3067

    The smart city concept as a method of building urban resilience to threats: Evidence from Poland by Wioletta Sylwia Wereda, Natalia Moch, Andrzej Skwarski

    Published 2025-07-01
    “…Objectives The functioning of cities is strongly influenced by local phenomena and global processes related to the urban natural environment. …”
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  8. 3068

    IoT Integrated Graphene Derivative-Based Capacitive Sensors with Machine Learning Classification for Precision Soil Moisture Monitoring Process by Ukani Neema Amish, Khera Shelej, Chakole Saurabh S.

    Published 2025-01-01
    “…Principal Component Analysis (PCA) was employed for dimensionality reduction and was able to capture more than 92% and 95% of data variance for the GO and rGO sensors, respectively. …”
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  9. 3069

    Application of legal enforcement measures for violation of financial legislation: problems of theory and practice by E. L. Vasyanina

    Published 2023-06-01
    “…The subject of the study is the legal norms that fix the procedure for applying coercive measures for violation of financial legislation, as well as doctrinal approaches and concepts on the chosen subject.The purpose of the article is: firstly, to rethink the leading role of the sectoral approach to the analysis and legal regulation of enforcement measures for violations of financial legislation, the development of which has led to the formation of alternative legal structures for regulating financial relations and parallel legal institutions of legal liability; secondly, in determining effective legal instruments aimed at streamlining the system of measures of state coercion applied to subjects of financial legal relations.The article examines: alternative, bypassing the current legislation, legal regulation of relations in the field of application of coercive measures; parallel legal institutions of legal responsibility for violation of financial legislation, as well as issues of streamlining the system of property sanctions for financial offenses.The use of general logical research methods, including analysis and synthesis, the formal legal and comparative legal methods, allowed the author to come to the following conclusions: (1) the emergence of alternative legal structures for regulating coercive measures for violation of financial legislation is caused by a mixture of state functions between federal executive authorities, the reason for which is a deviation from the concept of a three-tier system of public administration; (2) based on an industry approach, the well-established opinion of the legislator to determine the types of legal liability leads to the absence of conjugation of legislative acts in this area and, as a result, to the unreasonable application of legal liability measures, to double liability, as well as to problems in the field of determining the evidence base in cases of financial offenses; (3) as a basis for streamlining the system of coercive measures for violation of financial legislation, it is advisable to take an approach aimed at overcoming the gap between branches of law, the development of which is manifested in the expansion of the reception of universal legal structures in financial legislation and the application of the obligatory method of imposing property liability, which allows creating a different mechanism for imposing economic sanctions, corresponding to the riskbased approach to the implementation of control and supervisory activities. …”
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  10. 3070

    Effect of occlusal interference on condylar position and trajectory of movement: a randomized crossover-controlled trial by Miao Wei, Yu Xie, Bingbing Lv, Wenzhi Niu

    Published 2025-04-01
    “…Mandibular movements were recorded and measured by using jaw motion analysis system, during which the condylar trajectory and functional parameters, including sagittal condylar inclination (SCI) and Bennett Angle (BA) were analyzed to assess the condylar motion status. …”
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  11. 3071

    Photovoltaic and electrophysical properties of plasmon-enhanced organic solar cells by A.K. Zeinidenov, N.Kh. Ibrayev

    Published 2017-12-01
    “… A technique for depositing plasmon silver nanoparticles into various functional layers of an organic solar cell has been developed. …”
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  12. 3072

    The Effect of an advanced nurse practitioner led menopause clinic on quality of life and menopausal symptoms by Catriona Keye

    Published 2025-04-01
    “…The sample was randomly selected by identifying every second patient on a single medical surgery database. Statistical analysis was ascertained utilizing central tendency excel functionality. …”
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  13. 3073

    DEHP-Induced Glioblastoma in Zebrafish Is Associated with Circadian Dysregulation of PER3 by Shuhui Men, Jiayun Xu, Zhanhong Yang, Zhenguang Yan

    Published 2024-11-01
    “…Long-term exposure to DEHP can cause endocrine disruption and interfere with the organism’s normal functioning. In order to explore the potential effects of DEHP on the development of biological brain tissues, this study used bioinformatics analysis to confirm the diagnostic and prognostic value of PER3 in gliomas and further validated the neurotoxicity of DEHP using methods such as behavioral experiments and molecular biology in zebrafish. …”
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  14. 3074
  15. 3075

    Impact of carbon emission trading on urban electricity efficiency by SHI Yang, SONG Jia

    Published 2025-04-01
    “…[Objective] A thorough analysis of how the carbon emission trading system would affect the electricity efficiency of cities is of great significance for comprehensively assessing its economic effectiveness in energy conservation and emission reduction, and thereby promoting the realization of the “dual carbon” goals. …”
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  16. 3076

    Bucket working bodies with conveyor bottom: systematics and design features by Yu. M. Lyashenko, E. A. Revyakina, A. Yu. Lyashenko

    Published 2020-10-01
    “…Analysis of the bulk materials handling processes using existing loading appliances identified design flaws that affect the efficiency of their operation. …”
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  17. 3077

    Targeted pancreatic cancer therapy using 4-farnesyloxycoumarin conjugated nanocrystalline cellulose and Chitosan nanoparticles by Fariba Karoonkiani, Masoud Homayouni Tabrizi, Mohammad Taghi Goodarzi, Alireza Jalali

    Published 2025-05-01
    “…Dynamic light scattering (DLS) analysis revealed a Z-average particle size of 275.68 nm, with a polydispersity index of 0.3020. …”
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  18. 3078

    Untying the antimicrobial and antioxidant potential of silver nanoparticles fabricated from Typhonium trilobatum (L.) Schott by Sushree Ghosh, Sankar Narayan Sinha

    Published 2024-11-01
    “…The AgNPs were spherical with diameter ranges between 30 and 90 nm, negatively charged at −29.6 mV, crystalline in nature and surrounded by different active functional groups as evident by FTIR spectra analysis. …”
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  19. 3079

    Influential Factors in the Realization of the Third Place in Informal and Sociable Urban Spaces (Case Study: Informal Sitting Spaces Inside Tehran's Cultural and Commercial Complex... by Maryam Mohammadi Salek, Ali Asgari

    Published 2022-07-01
    “…Problem statement: The reduction of modern human living space, the obliteration of old neighborhoods and their centers, and the large-scale areas inherited from the modern time have reduced sustainable social interactions and the active presence of people in modern cities. …”
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  20. 3080