Potential induction of the relative mRNA expression levels of CYP450 by Zhicaowu-Hezi (Aconiti kusnezoffii radix preparata and Terminalia chebula Retz.) by Junxuan Zhu, Ming An, Weiting Wang, Jingjing Guo, Mengting Chen, Longlong Fang, Cen Wang, Dong Zhang, Guodong Wu

“…At the molecular level, RT-qPCR analysis demonstrated that Zhicaowu significantly suppressed hepatic CYP1a2, CYP2d2, CYP3a1, and CYP2c11 mRNA expression, while Hezi co-treatment restored their expression to normal or elevated levels.ConclusionHezi dose-dependently induced CYP450 enzyme activity, reversing Zhicaowu’s inhibition of CYP1a2/2d2/3a1/2c11 and markedly improving liver function and histopathology. …”
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Efficacy and safety of 3D-therapy at HCV-related subcompensated liver cirrhosis (genotype 1b) by P. O. Bogomolov, M. V. Matsiyevich, A. O. Buyeverov, V. D. Beznosenko, Ye. V. Fedosova, M. Yu. Petrachenkova, S. V. Koblov, K. Yu. Kokina, O. S. Kuzmina, N. V. Voronkova

“…The assessment of liver function compensation degree in 6 months after CAT termination demonstrated 3 to 4 points reduction of the Child-Pugh Score in 21 patients (33.9 %), 1 to 2 points in 35 patients (56.5 %). …”
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Mapping climate change-driven epidemics by Allyson Murray, Anna Ignaszak, Anna Ignaszak

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Transformations in physicochemical properties and pore structure of biochar derived from rice straw revealed by synchrotron techniques by Saowalak Somboon, Samuel Schlichenmaier, Kanjana Thumanu, Phakkhananan Pakawanit, Sujitra Yodda, Tanabhat-Sakorn Sukitprapanon, Phrueksa Lawongsa

“…Synchrotron-based XTM analysis revealed an 18% increase in total porosity, driven by a 19% rise in open-pore porosity and a 91% reduction in closed-pore porosity. …”
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An insight into pyocyanin: production, characterization, and evaluation of its in vitro antibacterial, antifungal, antibiofilm and in vivo anti-schistosomal potency by Marwa M. Eltarahony, Salwa S. Younis, Sara A. Abdel Salam, Fadwa M. Arafa

“…For antiparasitic potency, PYO-treated mice, at the juvenile stage, exhibited a significant reduction (p ≤ 0.05) in the total worm load (23.83 ± 2.79), with a reduction percentage of 34.41%, while PZQ-treated mice failed to show any significant reduction. …”
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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial. by John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Helen E Stevens, Linsey Porter, Deborah J Smyth, Daniel B Rainbow, Ricardo C Ferreira, Laura Esposito, Kara M D Hunter, Kevin Loudon, Kathryn Irons, Jennie H Yang, Charles J M Bell, Helen Schuilenburg, James Heywood, Ben Challis, Sankalpa Neupane, Pamela Clarke, Gillian Coleman, Sarah Dawson, Donna Goymer, Katerina Anselmiova, Jane Kennet, Judy Brown, Sarah L Caddy, Jia Lu, Jane Greatorex, Ian Goodfellow, Chris Wallace, Tim I Tree, Mark Evans, Adrian P Mander, Simon Bond, Linda S Wicker, Frank Waldron-Lynch

“…<h4>Background</h4>Interleukin-2 (IL-2) has an essential role in the expansion and function of CD4+ regulatory T cells (Tregs). Tregs reduce tissue damage by limiting the immune response following infection and regulate autoreactive CD4+ effector T cells (Teffs) to prevent autoimmune diseases, such as type 1 diabetes (T1D). …”
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Solid State Transformers: A Review—Part I: Stages of Conversion and Topologies by Dragoș-Mihail Predescu, Ștefan-George Roșu

“…In addition to magnetic circuit reduction, SSTs provide enhanced functionalities such as power factor correction, voltage regulation, and the capability to interface with various sources and loads. …”
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The nrfA-type microbial communities are widespread in hot springs of the Tibet-Yunnan geothermal zone by Xi Chen, Geng Wu, Zhicheng Yu, Fangming Li, Hongchen Jiang

“…Investigating the distribution of DNRA-functional bacteria is of great significance to understanding the source of biological nitrogen production in geothermal environments. …”
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Approaching the Entrepreneurs’ Point of View for the Public Sector by Papadopoulos Sotirios, Polychronidou Persefoni

“…Entrepreneurship is an important factor in economic development and the reduction of unemployment in any country. In Greece, entrepreneurship faces various challenges over time, which are usually influenced by the functioning of public administration and legislation. …”
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Sustainable Fabrication of Reddish Silk Fabric with Enhanced Color Intensity and Fastness Using Lycopene by Jiahong Zuo, Yuyang Zhou

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Cool temperature inhibits binary fission and results in phenotypic and transcriptomic changes that suggest inducible aging in Diadumene lineata by Clyde Eugene Makamure, Stephen Justinen, Daniel E. Martínez, David A. Hessinger, Isaac Kremsky

“…Functional enrichment analysis of the differentially expressed genes is consistent with an aging phenotype at 16oC, and suggests that the 16oC anemones may undergo gametogenesis prior to the development of senescence. …”
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Optimization of surgical treatment of cataract in patients with diabetes mellitus by Dmitriy Valentinovich Lipatov, Timofey Alexandrovich Chistyakov, Anatoliy Gennad'evich Kuz'min

“…Materials and methods. Analysis included data on 209 patients (221 eyes) treated from January 2008 to December 2009 in the Department ofRetinopathy and Ophthalmosurgey, Endocrinological Research Centre. …”
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Trophic Niche Partitioning of Freshwater Fish in Eutrophic Lakes: A Food Quality Perspective by Yiduo Luo, Fen Guo, Jing Lu, Xiaoguang Ouyang, Feilong Li, Wei Gao, Juan Tao, Yuan Zhang

“…Trophic niche analysis is essential for understanding species interactions and ecosystem functioning, especially in the context of environmental changes such as nutrient enrichment. …”
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High-Performance Identification and Control of MIMO (Multiple Input—Multiple Output) Experimental Module with Fractional-Order Approach Application by Alexandre Marques de Almeida, Alisson Luan Daga, Rafael Palma Setti Penteado Lanzarini, Ervin Kaminski Lenzi, Marcelo Kaminski Lenzi

“…The results demonstrate the superior performance and robustness of the FOPI-PSO fractional control, which achieves up to 79.6% reduction in ITAE and 72.1% reduction in ITSE criteria. …”
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Preparation and study of electrophysical and optical properties of TiO2-GO nanocomposite material by А.Zh. Zhumabekov, N.Kh. Ibrayev, Е.V. Seliverstova, G.B. Kamalova

“…The formation of nanocomposite was confirmed by FTIR analysis. It is shown that the functional groups characteristic of graphene oxide partially disappear in TiO2–GO, which indicates its partial reduction during synthesis. …”
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SOCIALLY-ENGINEERING ACTIVITY IN THE INFORMATION EPOCH by L. F. Matronina, A. N. Agafonov

“…Based on scientific methods (the method of systemic functional analysis, the comparative-analytical method, the hermeneutic approach and others) the article considers the features of social forecasting as a part of social engineering activities, describes the basic mechanisms of their influence on the attitude of public opinion capable of giving rise to anthropological risks and leading to a threat for information security. …”
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The Implementation of Quality Control Management for Student Guidance in Man 1 Parepare by Abdul Halik, St. Wardah Hanafie Das

“…This research method is case study at MAN 1 Parepare as the research object, data collecting technique are observation, interview, document study, triangulation, and Focus Group Discussion (FGD). Data analysis techniques are the identification and reduction of data, analysis, verification and conclusion. …”
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Identifying conducive contexts and working mechanisms of sedentary behaviour interventions in older adults: a realist review protocol as part of the ‘Stand UP Seniors’ project by Sebastien F M Chastin, Greet Cardon, Sofie Compernolle, Delfien Van Dyck, Kenneth Vanhove, Emelien Lauwerier

“…Sedentary behaviour is ubiquitous in older adults and has a strong link with age-related functional declines and chronic health conditions. Although several interventions have been developed aimed at the reduction of sedentary behaviour in older adults, little in-depth information is available on how these complex interventions work in different contexts. …”
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Pregnancy in obese mice protects selectively against visceral adiposity and is associated with increased adipocyte estrogen signalling. by Silvia M A Pedroni, Sophie Turban, Tiina Kipari, Donald R Dunbar, Kerry McInnes, Philippa T K Saunders, Nicholas M Morton, Jane E Norman

“…Attenuation of adipose inflammation was functionally confirmed by a 45% reduction of CD11b+CD11c+ adipose tissue macrophages (expressed as a proportion of all stromal vascular fraction cells) in HF pregnant compared to HF non pregnant animals (P<0.001). …”
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Technology and implementation of flax stripping in the primary flax processing line by R. A. Rostovtsev, V. G. Chernikov, S. V. Solovyov, I. B. Kazakov

“…The application of the factory's stripping technology is expected to ensure a 10 percent reduction in seed losses and an additional 6 percent reduction in production costs. …”
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