Peripheral blood transcriptomic differences predict depression status in individuals undergoing bariatric surgery by Rebecca Milton, Anna P. McLaughlin, Nicole Mariani, Melisa Kose, Zuzanna Zajkowska, Giulia Lombardo, Naghmeh Nikkheslat, Esperanza Perucha, Valeria Mondelli

“…Data were analysed for differential expression and gene set enrichment across the 3 groups of interest. Analysis of the differential gene expression showed seven genes differentially expressed across the three groups, with genes mainly involved in immune activation or synaptic function. …”
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Nature defect-mediated room temperature ferromagnetism in lead-free ferroelectric Ba(Zr0.2Ti0.8)O3: A first-principles study by V.T. Lam, N.H. Lam, D.Q. Van, N.T. Trang, J.P. Singh, N.H. Linh, N.H. Thoan, N.N. Trung, D.D. Dung

“…These magnetic moments primarily originate from the nearby oxygen atoms associated with vacancies, while the contributions from other cations, such as Zr, Ba, or Ti, are less significant. Our analysis of the optical properties further reveals the material’s diverse characteristics, including absorption, dielectric behavior, conductivity, reflectivity, refractive index, and loss function, all of which are crucial for the design of optoelectronic devices.…”
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Efficacy of Yijinjing-inspired exercises on sleep disorders in Parkinson’s disease: a controlled fNIRS study by Zekai Hu, Jing Shi, Jinyan Wang, Ting Liu, Yujia Li, Han Xue, Xueming Jin, Yiting Xue, Jie Wang, Xinhao Liu, Jun Hu

“…Between-group analysis revealed greater PSQI reduction in exercise versus control (Δ = -1.19 ± 0.85 vs. -0.19 ± 1.53; P = 0.001 after Bonferroni adjustment, Cohen's d = 0.87), but not versus music therapy (P = 0.018 > 0.0167). fNIRS confirmed cortical reorganization in dorsolateral prefrontal cortex (Brodmann Area 9; Channel 3) and primary motor cortex (Brodmann Area 4; Channel 9) at FDR-corrected P < 0.05. …”
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Intestinal Fut2 deficiency exacerbated alcohol‐related liver disease by disrupting nicotinamide metabolism by Liuying Chen, Zhongwei Yin, Luorui Shang, Hang Yuan, Wenkang Gao, Shuhan Wang, Shuyan Wang, Xiaohua Hou, Shenglan Yang, Huikuan Chu

“…Methods We generated mice with intestinal epithelial cell‐specific Fut2 knockout (Fut2△IEC) and established a chronic‐binge alcohol model. 16S rRNA sequencing and metabolomics analysis were used to reveal differences in the composition and function of faecal bacteria. …”
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Breaking down the recovery of O2 pathway: Peripheral extraction recovery pattern defines exercise capacity and clinical outcomes by Ahmed El Shaer, Mariana Garcia‐Arango, Anas Abed, Shannon Heffernan, Yuning Wang, Tashfeen Javed, Amirhossein Esmaeeli, Abdul Wahab Arif, Ran Tao, Naga Dharmavaram, James Runo, Jill N. Barnes, Farhan Raza

“…Physiologically, it elucidates the importance of skeletal muscle and peripheral vascular function.…”
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Can Zinc Oxide Nanoparticles Alleviate the Adverse Effects of Salinity Stress in <i>Coffea arabica</i>? by Jegnes Benjamín Meléndez-Mori, Yoiner K. Lapiz-Culqui, Eyner Huaman-Huaman, Marileydi Zuta-Puscan, Manuel Oliva-Cruz

“…Furthermore, the combined effect of ZnO-NP (100 mg L⁻¹) and salt resulted in a significant reduction in carotenoids, limiting their photoprotective function. …”
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The influence of the NRG1/ERBB4 signaling pathway on pulmonary artery endothelial cells by Jin‐Bo Huang, Qin Shen, Zhi‐Qi Wang, Song‐Shi Ni, Fei Sun, Yun Hua, Jian‐An Huang

“…Abstract This study aimed to examine the influence of the Neuregulin‐1 (NRG1)/ERBB4 signaling pathway on the function of human pulmonary artery endothelial cells (HPAECs) and investigate the underlying mechanisms. …”
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Angelica sinensis polysaccharide as potential protectants against recurrent spontaneous abortion: focus on autophagy regulation by Yeli Sun, Guohua Li, Mengwen Kong, Junyuan Li, Shuyun Wang, Yuan Tan

“…However, it remains uncertain whether its primary active component, Angelica sinensis polysaccharide (ASP), plays a definitive role in its therapeutic effects. The specific function and mechanism of ASP in the context of RSA require further investigation.MethodsIn this study, we sought to evaluate autophagy levels at the maternal-fetal interface in RSA patients and in an RSA mouse model treated with ASP, complemented by a comprehensive metabolomic analysis. …”
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Long-term clinical comparison of three different femoral stems in Total Hip Arthroplasty with femoral shortening in patients with high-riding hips by Kutalmis Albayrak, Yakup Alpay, Ozgur Ismail Turk, Muhammed Mert, Deniz Akbulut, Akif Albayrak

“…Abstract Background Developmental hip dysplasia is a common cause of hip arthrosis in young adults, necessitating total hip arthroplasty (THA) for improved function and pain relief. In cases of high-riding hips, transverse femoral shortening osteotomy is often required to facilitate reduction and prevent neurovascular complications. …”
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Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism by Yang Yang, Yang Yang, Qing Hong, Qing Hong, Xuehong Zhang, Zhenmin Liu, Zhenmin Liu

“…The expression of intestinal barrier protein was analyzed by qPCR to evaluate the intestinal barrier function. Alterations in gut microbiota and metabolites were assessed by 16S rDNA and non-targeted metabolomics.ResultsThe findings reveal that administering Bifidobacterium animalis BD400 orally led to a significant reduction in arthritis clinical scores and paw swelling thickness in CIA rats. …”
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Preclinical Research on Cinnamic Acid Derivatives for the Prevention of Liver Damage: Promising Therapies for Liver Diseases by Liseth Rubí Aldaba-Muruato, Brayan Escalante-Hipólito, Aldo Yoshio Alarcón-López, Pablo A. Martínez-Soriano, Enrique Angeles, José Roberto Macías-Pérez

“…LQM755 completely prevented albumin reduction, while LQM717 only partially prevented it. …”
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Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling by Tariq G. Alsahli, Khalid Saad Alharbi, Sattam Khulaif Alenezi, Reem Alqahtani, Muhammad Afzal, Nadeem Sayyed

“…Administration of aegeline at both tested doses led to a significant (P < 0.05) reduction in liver enzyme levels such as ALT, ALP, and AST—in rats with DOX-induced hepatotoxicity, indicating improved liver function. …”
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Green Synthesis and Characterization of Silver Nanoparticles Using Rice (Oryza sativa) and Spent Coffee (Coffea robusta) Grounds from Agricultural Waste§ by Nithiskanna Nallusamy, Nurul Afifah Mohd Kamal Rufadzil, Jasvini Bala Murally, Jing Zhi Liam, Wan Nor Dalila Wan Fauzi, Hawa Dalily Mohd Jefri, Al-Ashraf Abdullah Amirul, Seeram Ramakrishna, Sevakumaran Vigneswari

“…The AgNPs were synthesised using spent coffee grounds and rice husks, which are rich in biomolecules that serve as effective reducing and stabilising agents. FTIR analysis identified functional groups involved in the reduction and stabilisation of nanoparticles, while XRD confirmed their face-centred cubic (FCC) crystalline structure. …”
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Associations between endothelial dysfunction and clinical and laboratory parameters in children and adolescents with sickle cell anemia. by Rozana Santos Teixeira, Regina Terse-Ramos, Tatiane Anunciação Ferreira, Vinícius Ramos Machado, Marya Izadora Perdiz, Isa Menezes Lyra, Valma Lopes Nascimento, Ney Boa-Sorte, Bruno B Andrade, Ana Marice Ladeia

“…<h4>Conclusions</h4>Children and adolescents with SCA exhibit impaired endothelial function. Reductions in FMD values are associated with ACS. …”
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Environmental Impact Assessment of Heat Storage System in Rock-Bed Accumulator by Mateusz Malinowski, Stanisław Bodziacki, Stanisław Famielec, Damian Huptyś, Sławomir Kurpaska, Hubert Latała, Zuzanna Basak

“…The boundaries of the analyzed system include manufacturing the components of the storage device, land preparation for the construction of the accumulator, the entire construction process, including transportation of materials, and its operation in cooperation with a horticultural facility (foil tunnel) during one growing season, as well as the photovoltaic installation. The functional unit in the analysis is 1 square meter of rock-bed accumulator surface area. …”
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A genetic screen for attenuated growth identifies genes crucial for intraerythrocytic development of Plasmodium falciparum. by Bharath Balu, Naresh Singh, Steven P Maher, John H Adams

“…Large-scale functional analysis of the parasite genome is essential to pave the way for novel therapeutic intervention strategies against the disease and yet difficulties in genetic manipulation of this deadly human malaria parasite have been a major hindrance for functional analysis of its genome. …”
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Genetic variants in HLA-DQA1/DQB1 genes modulate the risk of gestational diabetes mellitus in a southern Chinese population by Lijie Nie, Yan Sun, Ruiqi Li, Qiulian Liang, Guocun Deng, Xinyu He, Yifei Zeng, Hui Zheng, Xinhe Xiao, Xiaodong Ding, Jian Huang, Xiangyuan Yu, Xiangyuan Yu

“…Multifactor dimensionality reduction (MDR) analysis revealed that rs9274666 was the best single locus model, whereas the 7-loci model was the best multifactor interaction model for predicting GDM risk (χ²=134.28, P&lt;0.0001). …”
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Use of Black Pepper Essential Oil to Produce a Healthier Chicken Pâté by Sandra S. Q. Rodrigues, Ana Leite, Lia Vasconcelos, Etelvina Pereira, Natália L. Seixas, Leticia Estevinho, Alfredo Teixeira

“…These results highlight the potential for optimizing BPEO or black garlic content to ensure both consumer acceptance and enhanced functional properties. While further analysis will help pinpoint the best formulation, the current findings are a promising step towards achieving an optimal balance.…”
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Two casting methods compared in patients with Colles' fracture: A pragmatic, randomized controlled trial. by Lauri Raittio, Antti P Launonen, Teemu Hevonkorpi, Toni Luokkala, Juha Kukkonen, Aleksi Reito, Minna K Laitinen, Ville M Mattila

“…<h4>Methods and findings</h4>We performed a pragmatic, randomized, controlled trial in three emergency centers in Finland. After closed reduction of the fracture, the wrist was placed in either volar-flexion and ulnar deviation cast or functional cast position. …”
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The role of the cast index in predicting clinical outcomes in elderly patients with distal radius fractures by Cumhur Deni̇z Davulcu, Muhammed Yusuf Afacan

“…This study investigates the relationship between the cast index and clinical, radiographic, and functional outcomes in patients aged 65 and older with distal radius fractures treated with closed reduction and casting. …”
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