Why might fears and worries persist after a pain education–grounded multimodal intervention for chronic back pain? A qualitative study by Rodrigo R. N. Rizzo, Benedict M. Wand, Hayley B. Leake, Edel T. O'Hagan, Adrian C. Traeger, Sylvia M. Gustin, G. Lorimer Moseley, Saurab Sharma, Aidan G. Cashin, Matthew K. Bagg, James H. McAuley, Samantha Bunzli

“…We used reflexive thematic analysis with an inductive approach. Results:. Twenty participants were interviewed (9 women and 11 men, median age = 54 years, median pain duration = 4 years, 13 reporting at least 30% pain reduction on the trial primary outcome). …”
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Myeloid gasdermin D drives early-stage T cell immunity and peripheral inflammation in a mouse model of Alzheimer’s disease by Wenjuan Rui, Yuqing Wu, Yongbing Yang, Wenting Xie, Dengli Qin, Jie Ming, Zhihan Ye, Liu Lu, Ming Zong, Xianglong Tang, Lieying Fan, Sheng Li

“…Targeted inhibitor experiments and clinical correlation analysis were used to further verify the function of GSDMD in AD. …”
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Distributionally robust hybrid energy management in smart mining using process-coupled primal-dual mirror descent by Dawei Wang, Yifei Li, Cheng Gong, Tianle Li, Fang Wang, Shanna Luo, Jun Li

“…Numerical results indicate a 25.4% reduction in operational costs, a 31.2% cut in carbon emissions, and consistent adherence to safety constraints within a 3% tolerance under all uncertainty scenarios. …”
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PSYCHOLOGICAL CHARACTERISTICS IN PATIENTS WITH CHRONIC HEART FAILURE WAITING FOR HEART TRANSPLANTATION by R. Yu. Shindrikov, A. A. Velikanov, E. A. Demchenko, V. M. Tishkova, O. Yu. Shchelkova

“…A statistically significant reduction in the overall level of cognitive function in patients with concomitant diabetes mellitus was found in comparison with patients without it (U = 61) at p = 0.033; According to the data of SDS depressive symptoms in patients with IHD are more pronounced in comparison with patients with dilated cardiomyopathy U = 47 (p = 0.019).…”
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SGLT2 inhibitors in preventing progression of chronic kidney disease in patients with type 2 diabetes: a literature review by Michał Szczepański, Marcin Kuliga, Mateusz Bajak, Julia Słowik, Julia Inglot, Jadwiga Inglot, Dominik Maciej Feret, Daniel Zapasek, Maciej Mamczur, Damian Sowa

“…Clinical studies have demonstrated significant therapeutic benefits, including a reduction in albuminuria and improvement in renal function. …”
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Differential patterns of the relationship between exercise dose and mortality risk across severities of airflow limitation: a prospective cohort study with a 5-year follow-up perio... by Yide Wang, Hongxia Duan, Yingqi Wang, Yidie Bao, Linhong Jiang, Xiaoyu Han, Fengsen Li, Peijun Li, Weibing Wu, Xiaodan Liu

“…Cox proportional hazards models were used to evaluate PA–mortality associations, with penalized spline analysis detecting threshold effects. Results: Identified thresholds were 41.50 MET·h/week (95% CI: 23.03–64.22) for normal lung function and 13.21 MET·h/week (95% CI: 9.67–16.14) for GOLD 1. …”
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Allopurinol in the complex therapy of acute decompensation of heart failure by Laura H. Sarieva, Marina D. Muksinova, Svetlana N. Nasonova, Igor V. Zhirov, Sergey N. Tereshchenko

“…Significant changes in C-reactive protein levels were found in both groups at discharge. The analysis of echocardiographic parameters revealed a significantly increased left ventricular ejection fraction, a reduction in inferior vena cava size, and a decrease in systolic pressure in the pulmonary artery in both groups. …”
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High Antennal Expression of <i>CYP6K1</i> and <i>CYP4V2</i> Participate in the Recognition of Alarm Pheromones by <i>Solenopsis invicta</i> Buren by Xinyi Jiang, Jiacheng Shen, Peng Lin, Youming Hou

“…To understand whether the highly expressed CYPs in the antennae play an olfactory function in <i>Solenopsis invicta</i> worker, in this study, we find six highly expressed antennal CYPs from the transcriptome of <i>S. invicta</i>. …”
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EFFECTIVENESS OF DISTRACTION AND ORTHOGNATHIC INTERVENTION IN THE TREATMENT OF MESIAL OCCLUSION IN PATIENTS WITH MAXILLARY UNDERDEVELOPMENT by І. Скрипник, С. Шнайдер, О. Дєньга, Ж. Новікова, С. Рачинський, О. Демид

“… Mesial occlusion is a complex orthodontic pathology that adversely affects facial aesthetics, masticatory function, and patient quality of life, making timely treatment critical. …”
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An orally-administered nanotherapeutics with gold nanospheres supplying for rheumatoid arthritis therapy by re-shaping gut microbial tryptophan metabolism by Chuan Yang, Langlang Xie, Zihan Deng, Hongbo Ai, Tingwen Xiang, Xiaojing Yan, Zhiguo Ling, Shiyu Xiao, Yong Tang, Gang Huang, Fei Luo, Yueqi Chen

“…Specifically, GNS notably enriched the probiotic genus Ligilactobacillus while restoring intestinal barrier function by upregulating tight junction proteins Claudin-1 and ZO-1. …”
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Comparison of Clinical Outcomes Between Fluoroscopic and Computer Tomographic Guidance in Concurrent Use of Radiofrequency Ablation and Vertebral Augmentation in Spinal Metastases:... by Qing Zhao Ruan, Syena Sarrafpour, Jamal Hasoon, R. Jason Yong, Christopher L. Robinson, Matthew Chung

“…This combination therapy of RFA with VA, which could be performed under CT or fluoroscopy, has in recent years been recognized as highly successful for pain control and functional restoration of metastatic spine lesions. …”
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PERAN AKSES PERMODALAN NON PERBANKAN MELALUI PROGRAM PNM MEKAAR DALAM PENGEMBANGAN UMKM PEREMPUAN DI KOTA SUNGAI PENUH by Khinanthi Adellia Pratami, Zul Ihsan Mu'arrif

“…The study uses a qualitative methodology with a phenomenological method, where data is collected through in-depth interviews with 10 women MSME entrepreneurs who are recipients of loans from PNM Mekaar. Data reduction, data display, and conclusion drawing are all part of the Miles and Huberman model of analysis. …”
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Influence of Ordinary Cigarettes and Their Substitute IQOS^® on Secretory Immunoglobulin A in Unstimulated Saliva by Niкolai Pavlov, Ivelina Popova-Sotirova, Nina Musurlieva, Ralitsa Raycheva, Konstantin Trifonov, Maria Atanasova, Radka Cholakova

“…Smoking is known to negatively affect immune function, but data on the impact of heated tobacco products such as IQOS^® on sIgA levels are limited. …”
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Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells by Giulia Girolimetti, Sinforosa Gagliardi, Paola Cordella, Grazia Bramato, Riccardo Di Corato, Roberta Romano, Flora Guerra, Cecilia Bucci

“…Seahorse assays, Western blot analysis, mitochondrial staining, and Transmission Electron Microscopy (TEM) were used to assess silencing effects on mitochondrial structure and functioning. …”
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Women-specific reference ranges for serum TSH in Liguria: the impact of age and year of collection in a single-center cross-sectional study by Massimo Giusti, Marilena Sidoti

“…Abstract Background TSH is the first-line test of thyroid function, and the normal TSH references provided by manufacturers are generally used in diagnoses. …”
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Endometrial stromal Menin supports endometrial receptivity by maintaining homeostasis of WNT signaling pathway through H3K4me3 during WOI by Xin Xu, Yichen Han, Keer Jin, Weina Xu, Huanyu Zhang, Yana Ma, Xiangjuan Li, Haibin Wang, Mengying Liu, Xiaona Lin

“…Stromal Menin deficiency not only impairs the decidualization of stromal cells but also negatively impacts the differentiation of epithelial cells through HAND2-FGFs-FGFR axis. Transcriptome analysis reveals that MEN1 knockdown in stromal cells induces the aberrant activation of the WNT signaling pathway, and in vivo experiments show it is associated with a significant reduction in the weight of implantation sites. …”
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Synergizing Multi-Temporal Remote Sensing and Systemic Resilience for Rainstorm–Flood Risk Zoning in the Northern Qinling Foothills: A Geospatial Modeling Approach by Dong Liu, Jiaqi Zhang, Xin Wang, Jianbing Peng, Rui Wang, Xiaoyan Huang, Denghui Li, Long Shao, Zixuan Hao

“…This framework quantitatively evaluates the nonlinear response mechanisms of town–village systems to flood disasters, emphasizing the synergistic effects of spatial scale, morphology, and functional organization. The proposed framework uniquely integrates three innovative modules: (1) a hybrid risk identification engine combining normalized difference vegetation index (NDVI) temporal anomaly detection and spatiotemporal hotspot analysis; (2) a morpho-functional resilience quantification model featuring a newly developed spatial morphological resilience index (SMRI) that synergizes landscape compactness, land-use diversity, and ecological connectivity through the entropy-weighted analytic hierarchy process (AHP); and (3) a dynamic scenario simulator embedding rainfall projections into a coupled hydrodynamic model. …”
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The Effects of Endoscopic Third Ventriculostomy Versus Ventriculoperitoneal Shunt on Neuropsychological and Motor Performance in Patients with Idiopathic Normal Pressure Hydrocepha... by Gianluca Scalia, Nicola Alberio, Pietro Trombatore, Mariangela Panebianco, Grazia Razza, Gianluca Galvano, Giovanni Federico Nicoletti, Francesca Graziano

“…Preoperative and postoperative evaluations will include comprehensive cognitive and motor assessments, standardized quality-of-life instruments, and advanced neuroimaging techniques such as MRI with flowmetry and diffusion tensor imaging (DTI). Functional outcomes will also be evaluated using navigated transcranial magnetic stimulation (nTMS) and wearable motion analysis systems. …”
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C-X-C motif chemokine ligand 1 derived from oral squamous cell carcinoma promotes cancer-associated fibroblast differentiation and tumor growth by Soon Chul Heo, In-hye Nam, Bo Ram Keum, Yeo Gyun Yun, Jae-Yeol Lee, Hyung Joon Kim

“…In vivo, co-injection of SCC25 cells with GFs significantly promoted tumor growth and stromal CAF marker expression, whereas CXCR2 knockdown in GFs led to a ~ 40% reduction in tumor volume and reduced αSMA/vimentin-positive CAFs. …”
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Dominant performance parameter and technical limits of surfactants for oil displacement by Yabing Guo, Youqi Wang, Zengmin Lun, Maolei Cui

“…In chemical flooding, emulsification and interfacial tension (IFT) reduction are crucial for enhanced oil recovery (EOR). …”
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