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2461
Coilin Affects the Prognosis of Hepatocellular Carcinoma Through Cell Cycle and Apoptosis
Published 2025-02-01“…The relationship between COIL expression and clinical outcomes was assessed, and COIL’s biological function in HCC was investigated through cellular assays.Results: Analysis of cell lines and HCC tissue samples revealed that COIL mRNA or protein expression levels were significantly higher in HCC cell lines/tissues compared to normal liver cells/tissues. …”
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2462
Silencing circ_0043256 inhibited CoCl2-induced proliferation, migration, and aerobic glycolysis in gastric cancer cells
Published 2025-01-01“…The impact of circ_0043256 silencing on the proliferation, migration, apoptosis, and aerobic glycolysis of MKN-45 and AGS cells induced by CoCl2 was assessed through the utilization of CCK-8, wound healing assay, flow cytometry, and metabolic analysis. The interaction between circ_0043256 and miR-593-5p, as well as the involvement of the miR-593-5p/RRM2 axis in gastric cancer, were confirmed via luciferase assay, Western blot, and bioinformatics analysis. …”
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2463
Peculiarities of children’s health status after acute respiratory viral infections: a look at the problem, ways to solve it
Published 2024-10-01“…This determines the urgency of finding appropriate methods of correction with etiopathogenetic (inhibition of oxidative stress, reduction of acidosis and hypoxia, restoration of liver function), immunoregulatory (improvement of the immune system), and symptomatic (improvement of appetite) effects. …”
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2464
CD73low B-cell phenotypes and distinct cytokine profiles in patients with active anti-Jo-1 antibody positive idiopathic inflammatory myopathies
Published 2025-04-01“…Objectives We performed multiparameter phenotyping of peripheral B cells in anti-Jo-1 antibody positive idiopathic inflammatory myopathies (IIM) to delineate disease-associated immunological profiles and the influence of B cells on disease activity.Methods Purified B cells from peripheral blood mononuclear cells from 16 patients with anti-Jo-1 antibody positive IIM (7 with untreated active IIM, 4 with active and treated IIM and 5 with inactive IIM) were analysed by multiparameter spectral flow cytometry. Dimensionality reduction and clustering analysis were applied to pre-gated CD19+B cells. …”
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2465
Metabolic profiling and insecticidal activities of Rosmarinus officinalis L. for the management of Aphis craccivora Koch and Planococcus lilacinus Cockerell
Published 2025-04-01“…Further, EAE significantly inhibited in vivo enzyme acetylcholinesterase (AChE), glutathione-S-transferase (GST), and mixed function oxidase (MFO) in A. craccivora after 24 and 48 h. …”
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2466
Developing a novel aging assessment model to uncover heterogeneity in organ aging and screening of aging-related drugs
Published 2025-07-01“…Abstract Background The decline in organ function due to aging significantly impacts the health and quality of life of the elderly. …”
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2467
Ultrasound Stimulation Modulates Microglia M1/M2 Polarization and Affects Hippocampal Proteomic Changes in a Mouse Model of Alzheimer's Disease
Published 2024-11-01“…This study investigated the effects of ultrasound stimulation on the proportion and function of microglia of different phenotypes, as well as on the levels of inflammatory factors. …”
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2468
RAISE study protocol: a cross-sectional, multilevel, neurobiological study of resilience after individual stress exposure
Published 2021-01-01“…We will use dimension reduction techniques (principal component analysis) on standard-normally transformed individual parameters of mental health, social functioning and CA to calculate a composite measure of adaptive (ie, ‘resilient’) psychosocial functioning. …”
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2469
Examining the Design of Different Types of DM EMI Filters and Their Effect on EMI Noise and Control Characteristics for Cuk DC-DC Converter
Published 2023-01-01“…After that, transfer functions of each filter topology are obtained. Lastly, the entire transfer functions of the system using both the Cuk converter and each filter are acquired, separately. …”
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2470
Bleb Morphology Using Anterior-Segment Optical Coherence Tomography after Ahmed Glaucoma Valve Surgery with Tenon Capsule Resection
Published 2020-01-01“…AS-OCT was beneficial in the analysis of bleb morphology after AGV surgery where there were more diffuse functioning multicystic blebs and less thinning in the bleb wall thickness during the hypertensive phase after resection of the Tenon capsule, which might be related to the less incidence of fibrosis around the surgical site.…”
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2471
Geographical indication certification of agricultural products and agricultural carbon emissions—empirical evidence from China
Published 2025-08-01“…Additional heterogeneity analysis shows that the carbon emission reduction effects of GIAP vary substantially across different regions, economic zones, functional areas, and “hot” and “cold” spatial clusters. …”
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2472
Development of an onboard monitoring device for freight car shock-absorbing device’s technical condition
Published 2019-11-01“…The study enabled development and manufacturing of a mockup onboard monitoring device freight car shock-absorbing device’s technical condition, with its functional capabilities described. To increase the diagnostics accuracy, technology defi ning failure criteria of the controlled unit and reduction of its operation effectiveness is developed. …”
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2473
Effect of recasting on the thickness of metal-ceramic interface of nickel-chromium and cobalt-chromium alloys
Published 2008-01-01“…Metal-ceramic interface determines their functional integrity and prevents damages on ceramics during mastication. …”
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2474
Seismic Vibration Control and Multi-Objective Optimization of Transmission Tower with Tuned Mass Damper Under Near-Fault Pulse-like Ground Motions
Published 2024-11-01“…Based on the obtained analysis results, artificial neural network (ANN) is trained to predict the vibration reduction ratios of peak responses and the corresponding vibration reduction cost. …”
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2475
Economic essence of biofuel as an object of accounting
Published 2025-03-01“…Modern problems of environmental pollution and reduction of exhaustible energy resources pose an urgent task for society to find alternative, environmentally friendly energy sources. …”
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2476
Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial
Published 2025-05-01“…Secondary analysis indicated significant improvements in psychosocial function at 36 and 48 weeks. …”
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2477
Investigation of DC-Biased Optical OFDM With Precoding Matrix for Visible Light Communications: Theory, Simulations, and Experiments
Published 2018-01-01“…The simulation and experiment results are consistent with our theoretical analysis.…”
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2478
Integrated decision support system for optimizing time and cost trade offs in linear repetitive construction projects
Published 2025-06-01“…Specifically, GA achieved approximately a 3.25% reduction in direct costs, a 20% reduction in indirect costs, and a 7% reduction in total construction costs. …”
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2479
From paediatric trauma to adult outcomes: surgical management and long-term results in paediatric femoral neck fractures
Published 2025-08-01“…Abstract Background The current study aimed to examine the short- and long-term relationship between complications and radiologic and functional outcomes in surgically treated patients with Delbet type II and type III paediatric femoral neck fractures (PFNFs). …”
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2480
Life Cycle Assessment Comparison of Orchard Tractors Powered by Diesel and Hydrogen Fuel Cell
Published 2024-09-01“…This article presents a comparative analysis, according to different impact categories, of the life cycle impacts of a traditional diesel-powered tractor and a fuel-cell hybrid tractor, designed considering operative requirements and functional constraints. …”
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