Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial. by John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Helen E Stevens, Linsey Porter, Deborah J Smyth, Daniel B Rainbow, Ricardo C Ferreira, Laura Esposito, Kara M D Hunter, Kevin Loudon, Kathryn Irons, Jennie H Yang, Charles J M Bell, Helen Schuilenburg, James Heywood, Ben Challis, Sankalpa Neupane, Pamela Clarke, Gillian Coleman, Sarah Dawson, Donna Goymer, Katerina Anselmiova, Jane Kennet, Judy Brown, Sarah L Caddy, Jia Lu, Jane Greatorex, Ian Goodfellow, Chris Wallace, Tim I Tree, Mark Evans, Adrian P Mander, Simon Bond, Linda S Wicker, Frank Waldron-Lynch

“…Primary analysis of the evaluable population (n = 39) found that the optimal doses of aldesleukin to induce 10% and 20% increases in Tregs were 0.101 × 106 IU/m2 (standard error [SE] = 0.078, 95% CI = -0.052, 0.254) and 0.497 × 106 IU/m2 (SE = 0.092, 95% CI = 0.316, 0.678), respectively. …”
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Designing a Dynamic Model for Evaluating Construction Investment Projects A System Dynamics Approach by Majid Moatamedi, Mohammad Hossein Darvish Motevlli

“…Based on this, the inflation reduction scenario was investigated. With a 15% decrease in inflation, we have seen a relatively significant price decrease and the investment rate has decreased very little. …”
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Prediction of Soil Carbon Sequestration in Rangelands Regarding the Depth and Elevation of Sample Locations using Adaptive Neuro-Fuzzy Inference System (ANFIS) (Case Study: Lar Wat... by zeinab jafarian, zhila ghorbani

“…Conclusion: The increase in the correlation coefficient and the reduction of the mean error deviation in the ANFIS method compared to the linear multivariate regression show that the ANFIS method is more successful in estimating the amount of soil CS under the effects of various factors in the studied land use. …”
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Measuring and estimation of suspended sediment variation using sediment rating curve approach in Mereg River by Sohila Aghabeigi Amin, Heidar Mirzaei

“…The calculation of the estimation error indicates that there is no difference, and in some cases, the error is raised by creating a separate curve for the rising and falling limbs. …”
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Pharmacokinetics of Pegaspargase with a Limited Sampling Strategy for Asparaginase Activity Monitoring in Children with Acute Lymphoblastic Leukemia by Cristina Matteo, Antonella Colombini, Marta Cancelliere, Tommaso Ceruti, Ilaria Fuso Nerini, Luca Porcu, Massimo Zucchetti, Daniela Silvestri, Maria Grazia Valsecchi, Rosanna Parasole, Luciana Vinti, Nicoletta Bertorello, Daniela Onofrillo, Massimo Provenzi, Elena Chiocca, Luca Lo Nigro, Laura Rachele Bettini, Giacomo Gotti, Silvia Bungaro, Martin Schrappe, Paolo Ubezio, Carmelo Rizzari

“…This model predicts the AUC with 6% average error and 35% maximum error compared to the AUC estimated with all available measures. …”
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Identification and analysis of factors affecting the technology transfer process in the power train of automotive (Case study : Iran Khodro Industrial Group) by ٍEbrahim Doostzadeh, Abbas Toloie Ashlaghi, Manochehr Manteghi, Reza Radfard

“…Additionally, the reduction of five other gaps including gearbox vibration, gearbox durability, axle durability, engine noise and gearbox noise requires special attention to the infrastructure factor. …”
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Estimation of long-term gridded cloud radiative kernel and radiative effects based on cloud fraction by X. Liu, T. He, Q. Wang, X. Xiao, Y. Ma, Y. Wang, S. Luo, L. Du, Z. Wu, Z. Wu

“…In Arctic-wide validation experiments, the root mean square error (RMSE) was decreased by approximately 2.5 W m<span class="inline-formula">⁻²</span>, and the bias was reduced by 1.23 W m<span class="inline-formula">⁻²</span>, which was an improvement of 8.7 % (reduction in RMSE) against the CERES EBAF (Clouds and the Earth's Radiant Energy System Energy Balanced and Filled). …”
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Workplace Incivility and Job Alienation: Analyzing the Mediating Role of Social Capital and the Moderating Role of Psychological Capital by Fariborz Fathi Chegeni, Mostafa OmidNezhad

“…Based on the population size, a sampling error of 5%, and a confidence level of 95%, the required sample size was calculated to be 300 individuals. …”
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<i>PI-D^Æ</i>: An Adaptive PID Controller Utilizing a New Adaptive Exponent (Æ) Algorithm to Solve Derivative Term Issues by Juan M. Barrera-Fernández, Juan Pablo Manzo Hernández, Kevin Miramontes Escobedo, Alberto Vázquez-Cervantes, Julio-César Solano-Vargas

“…Simulation results on two systems demonstrate that <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>P</mi><mi>I</mi></mrow></semantics></math></inline-formula>-<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mrow><mi>D</mi></mrow><mrow><mi>Æ</mi></mrow></msup></mrow></semantics></math></inline-formula> achieves a 90% faster response time, a 35% reduction in peak time, and a 100% improvement in settling time compared with conventional PID controllers, all while maintaining a near-zero steady-state error even under external disturbances. …”
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Upper-Bound Analysis of Slope Reliability Considering Anisotropic Spatial Variability and Reinforcement with Anti-slide Piles by ZHAO Zi-hao, WANG Jia-rui, FU Tao-tao, ZHU En-lin

“…Finally, the strength reduction method is employed to calculate the safety factor at the critical state of slope failure. …”
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Mapping football tactical behavior and collective dynamics with artificial intelligence: a systematic review by José E. Teixeira, José E. Teixeira, José E. Teixeira, José E. Teixeira, José E. Teixeira, José E. Teixeira, Eduardo Maio, Eduardo Maio, Eduardo Maio, Pedro Afonso, Pedro Afonso, Samuel Encarnação, Samuel Encarnação, Samuel Encarnação, Guilherme F. Machado, Guilherme F. Machado, Ryland Morgans, Tiago M. Barbosa, Tiago M. Barbosa, António M. Monteiro, António M. Monteiro, Pedro Forte, Pedro Forte, Pedro Forte, Ricardo Ferraz, Ricardo Ferraz, Luís Branquinho, Luís Branquinho, Luís Branquinho, Luís Branquinho

“…Concretely, the tactical behavior was expressed by spatiotemporal tracking data using convolutional neural networks, recurrent neural networks, variational recurrent neural networks, and variational autoencoders, Delaunay method, player rank, hierarchical clustering, logistic regression, XGBoost, random forest classifier, repeated incremental pruning produce error reduction, principal component analysis, and T-distributed stochastic neighbor embedding. …”
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Assessment the Effects of Climate Change on the Degree of Heating and Cooling Days of Iran by Hasan Zolfaqari, Hamid Rahimi, Rohollah Oji

“…It is expected to stabilize and reduce the need for cooling in the Alborz and Zagros ridgetop. In spite of the reduction in heating demand for the country, the horizons are foreseen. …”
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Supplemental parenteral nutrition within an enhanced recovery program for open pancreatoduodenectomy for cancer: a pragmatic, multicenter, randomized controlled trialResearch in co... by Luca Gianotti, Salvatore Paiella, Giovanni Capretti, Nicolò Pecorelli, Isabella Frigerio, Marta Sandini, Alessandro Fogliati, Eleonora Vico, Marco Braga, Christian Cotsoglou, Alfonso Pedalino, Giuseppe Malleo, Simone Ricchitelli, Sabrina Caspani, Giovanni Guarneri, Alessia Vallorani, Alessandro Giardino, Elettra Pasqualoni, Roberto Salvia, Alessandro Zerbi, Massimo Falconi, Giovanni Butturini, Davide Paolo Bernasconi

“…The expected complication rate was 60%, and the type I error rate was set at 5%. Registration at ClinicalTrials.gov (#NCT04438447). …”
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Development of In Vitro Potency Methods to Replace In Vivo Tests for Enterovirus 71 Inactivated Vaccine (Human Diploid Cell-Based/Vero Cell-Based) by Xuanxuan Zhang, Li Yi, Dan Yu, Jun Li, Xintian Li, Xing Wu, Fan Gao, Qian He, Wenhui Wang, Kaiwen Wang, Zejun Wang, Zhengling Liu, Yadong Li, Yong Zhao, Huiyi Li, Xiao Ma, Qingbing Zheng, Longfa Xu, Tong Cheng, Rui Zhu, Jing Guo, Jing Li, Qunying Mao, Zhenglun Liang

“…To align with 3R (Replacement, Reduction, Refinement) principles and enhance quality control, this study referred to WHO guidelines and the European Pharmacopoeia to develop in vitro relative potency (IVRP) methods. …”
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Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning by Bronagh Walsh, Carole Fogg, Tracey England, Sally Brailsford, Paul Roderick, Scott Harris, Simon Fraser, Andrew Clegg, Simon de Lusignan, Shihua Zhu, Francesca Lambert, Abigail Barkham, Harnish Patel, Vivienne Windle

“…In secondary care settings, there could also be reductions in ED attendances, hospital admissions and outpatient appointments. …”
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Eradication of Helicobacter pylori for prevention of aspirin-associated peptic ulcer bleeding in adults over 65 years: the HEAT RCT by CJ Hawkey, Anthony J Avery, Carol AC Coupland, Colin J Crooks, Jennifer S Dumbleton, FD Richard Hobbs, Denise Kendrick, Michael Moore, Clive Morris, Gregory Rubin, Murray Smith, Diane Stevenson

“…Omitting mention of death due to peptic ulcer bleeding from the protocol was an error, but it did not affect the analysis, as there were no pre-hospitalisation deaths. …”
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The use of modern military technologies in the light of the law of weapons and the law of targeting by Behzad Seyfi

“…However, the foundations of international humanitarian law emphasize only the reduction of human pain and suffering. Therefore, the basic principles of humanitarian rights are applied to all new tools and methods without compromise, and any tools and methods that do not comply with the basic rules of international humanitarian and customary law are prohibited. …”
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Benefits of aldosterone receptor antagonism in chronic kidney disease: the BARACK-D RCT by F D Richard Hobbs, Richard McManus, Clare Taylor, Nicholas Jones, Joy Rahman, Jane Wolstenholme, Louise Jones, Jennifer Hirst, Sam Mort, Ly-Mee Yu

“…Due to the higher than anticipated measurement error/fluctuations, the eligible range was extended to 30–50 ml/minute/1.73 m2 following the initial recruitment period. …”
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CREATING THE KULTUK POLYGON FOR EARTHQUAKE PREDICTION: VARIATIONS OF (234U/238U) AND 87SR/86SR IN GROUNDWATER FROM ACTIVE FAULTS AT THE WESTERN SHORE OF LAKE BAIKAL by S. V. Rasskazov, E. P. Chebykin, A. M. Ilyasova, E. N. Vodneva, I. S. Chuvashova, S. A. Bornyakov, A. K. Seminsky, S. V. Snopkov, V. V. Chechel'nitsky, N. A. Gileva

“…Therefore, an indirect assessment of oxidation‐reduction properties of the medium can be based on uranium concentrations. …”
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Machine Learning‐Driven Extraction of Hybrid Compact Models Integrating Neural Networks and Berkeley Short‐Channel Insulated‐Gate Field‐Effect Transistor Model‐Common Multigate for... by Seungjoon Eom, Seunghwan Lee, Hyeok Yun, Kyeongrae Cho, Soomin Kim, Rockhyun Baek

“…Compared with the BSIM model alone, error reductions of 75, 70, 39, 85, and 81%, respectively, were achieved. …”
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