Targeting ERRs to counteract age-related muscle atrophy associated with physical inactivity: a pilot study by Roberto Bonanni, Angela Falvino, Antonio Matticari, Anna Maria Rinaldi, Giovanna D’Arcangelo, Giovanna D’Arcangelo, Pierangelo Cifelli, Riccardo Iundusi, Elena Gasbarra, Virginia Tancredi, Virginia Tancredi, Ida Cariati, Umberto Tarantino

“…In addition, significantly higher expression of NOX4, concomitant with reduced levels of SIRT1, PGC-1α, ERRα, and FNDC5, was detected in the muscle tissue of inactive women. …”
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Analysis of the capabilities of an information system for improving sleep quality based on biometric data analysis by M.S. Graf, A.V. Yakoniuk, D.V. Krant, I.I. Golovach

“…The study shows that these technologies not only improve sleep conditions, but also have a positive impact on the user's overall health and reduce stress levels. The system is able to function independently thanks to the use of machine learning algorithms, including LSTM for prediction, Kalman filter for data cleaning, Isolation Forest for anomaly detection, and K-means for clustering sleep patterns.…”
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THE METHOD OF CALCULATION OF COEFFICIENTS OF THE PHASE ABERRATIONS OF AXIALLY ASYMMETRIC DUAL REFLECTOR ANTENNAS by B. N. Laskin, E. A. Bolelov

“…Aerodrome-enroute surveillance radar systems (ARSR) of civil aviation are designed for detection of aerial objects and determination of their range and movement parameters. …”
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A directed greybox fuzzer for windows applications by Xin Ren, Peng-fei Wang, Xu Zhou, Kai Lu

“…This paper proposes WinDGF, a novel directed greybox fuzzer for Windows applications that addresses challenges including target function localization in persistent testing, GUI bypassing, and fitness metric calculation. …”
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The Effect of SMOTE and Optuna Hyperparameter Optimization on TabNet Performance for Heart Disease Classification by Danang Wijayanto, Robert Marco, Acihmah Sidauruk, Mulia Sulistiyono

“…Heart disease is a medical condition affecting the cardiovascular system, disrupting blood circulation and reducing cardiac function efficiency, which can lead to severe health complications. …”
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Research progress on the application of digital technology in the diagnosis and treatment of tooth wear by HE Yi, WANG Dingjie, XIAO Yuhong

“…Tooth wear not only affects the oral function and esthetics of patients but may also lead to tooth sensitivity, temporomandibular joint diseases, and other related complications. …”
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Lightweight deep learning system for automated bone age assessment in Chinese children: enhancing clinical efficiency and diagnostic accuracy by Pang Hai, Zhang Bin, Liu Kesheng, Li Cong, Xu Fei

“…In the first stage, the YOLOv8 algorithm precisely localizes 13 key epiphyses in hand radiographs, achieving a mean Average Precision (mAP) of 99.5% at Intersection over Union (IoU) = 0.5 and 94.0% within IoU 0.5–0.95, demonstrating robust detection performance. The second stage employs a modified EfficientNetB3 architecture for fine-grained epiphyseal grade classification, enhanced by the Rectified Adam (RAdam) optimizer and a composite loss function combining center loss and weighted cross-entropy to mitigate class imbalance. …”
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CARBON-FIBRE-REINFORCED POLYMER PARTS EFFECT ON SPACECRAFT OPTOELECTRONIC MODULE LENS SCATTERING by S. S. Kolasha, R. V. Fiodortсev, A. V. Starovoitov

“…The work included experimental study in order to determine bidirectional reflectance distribution function by goniometric method for LUP-0.1 carbon fabric check test pieces of EDT-69U epoxy binder with EPOFLEX-0.4 glue layer and 5056-3.5-23-A aluminium honeycomb filler. …”
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Path Planning for Lunar Rovers in Dynamic Environments: An Autonomous Navigation Framework Enhanced by Digital Twin-Based A*-D3QN by Wei Liu, Gang Wan, Jia Liu, Dianwei Cong

“…A multi-dimensional reward function balances path efficiency, safety, energy, and time, while priority experience replay accelerates training convergence. …”
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Bridging molecular insights and clinical application: non-coding RNAs, targeted drug delivery, and metastatic breast cancer therapy by Sohini Chakraborty, Satarupa Banerjee

“…It also addresses the new advances in nanotechnology-based drug delivery systems (DDS) that function to enhance the specificity of treatments while simultaneously reducing systemic toxicity. …”
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Paying attention to distortion: improving the accuracy of multistep-ahead carbon price forecasting with shape and temporal criteria by Tong Niu, Yuan Chen, Tao Li, Shaolong Sun, Weigang Zhao, Mingjian Cui, Jiakang Wang, Shiyu Han, Jiujiang Li, Yunkai Zhai

“…However, current state-of-the-art carbon price forecasting models, which are trained primarily via the mean squared error loss function, struggle to deliver precise and timely forecasts. …”
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A YOLOv8n-T and ByteTrack-Based Dual-Area Tracking and Counting Method for Cucumber Flowers by Liyang Su, Shujuan Zhang, Hongtu Zhang, Xiangsen Meng, Xiongkui He

“…The YOLOv8n-T incorporates a Coordinate Attention (CA) mechanism and lightweight modules while optimizing the loss function, thereby improving floral feature extraction capabilities and reducing computational complexity. …”
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Robust Optical and SAR Image Matching via Attention-Guided Structural Encoding and Confidence-Aware Filtering by Qi Kang, Jixian Zhang, Guoman Huang, Fei Liu

“…Additionally, a match-aware multi-task loss function jointly enforces spatial consistency, affine invariance, and structural coherence for end-to-end optimization. …”
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Apical-out intestinal organoids as an alternative model for evaluating deoxynivalenol toxicity and Lactobacillus detoxification in bovine by Min Gook Lee, Bo Ram Lee, Poongyeon Lee, Soyoung Choi, Jong-Hui Kim, Mi-Hwa Oh, Jae Gyu Yoo

“…Therefore, we sought to investigate the possibility of replacing animal testing with bovine apical-out small intestinal organoids (Apo-IOs) by confirming the toxicity of mycotoxins and effectiveness of L. plantarum as mycotoxin-reducing agents. The characteristics and functions of Apo-IOs were first confirmed. …”
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Tannic acid mitigates salmonella-induced lung injury via gut-lung axis in broilers by Aoao Wu, Liu Xu, Yinzhu Zhang, Yuanyuan Zhu, You Wu, Jing Wu, Lixin Wen, Zhihang Yuan, Ji Wang

“…After a ten-day infection period, although Salmonella was not detected in the intestinal content of broilers, the infected broilers exhibited reduced body weight and compromised intestinal barrier function. …”
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An improved statistical bias correction method for Global Climate Model (GCM) precipitation projection: A case study on the CMCC-CM2-SR5 model projection in China’s Huaihe River Ba... by Yuning Luo, Ke Zhang, Wen Wang, Xinyu Chen, Jin Feng, Haijun Wang, Wei Liu, Cheng Guo, Cuiying Chen, Xiaozhong Wang

“…The Expert Team on Climate Change Detection and Indices (ETCCDI) extreme precipitation indices and spatial patterns of extreme precipitation in July 2020 in the observations and bias-corrected data were then compared to evaluate the effectiveness of these methods on capturing precipitation extremes.New hydrological insights for the region: Results show that the LS-EDCDF method outperforms the other three methods in correcting monthly CDFs, reducing biases, and preserving extreme precipitation. …”
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基于药物基因组学的急性缺血性卒中个体化抗栓治疗进展 Advances in Pharmacogenomics-Based Individualized Antithrombotic Therapy for Acute Ischemic Stroke by 杨佳洁，张亮，黄立安（YANG Jiajie, ZHANG Liang, HUANG Li’an ）

“…Patients carrying loss-of-function alleles such as CYP2C19*2 or CYP2C19*3 demonstrate diminished responses to standard antiplatelet therapy and cannot effectively reduce the risk of stroke recurrence. …”
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Revealing the physical restrictions of caecal influx in broilers through the use of solid and soluble markers by Paulien Vanderghinste, An Bautil, Michael R. Bedford, Gemma González-Ortiz, Chris Lamberigts, Imran Aslam, Maarten Roeffaers, Christophe M. Courtin

“…This study aimed to understand the physical limitations of caecal influx as a function of broiler age by using both solid and soluble markers. …”
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Drosophila pheromone-sensing neurons expressing the ppk25 ion channel subunit stimulate male courtship and female receptivity. by Vinoy Vijayan, Rob Thistle, Tong Liu, Elena Starostina, Claudio W Pikielny

“…Here we show that ppk25 is expressed and functions in neurons that detect female-specific pheromones and mediates their stimulatory effect on male courtship. …”
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Sirtuin 5 inhibits mitochondrial metabolism in liver cancer cells and promotes apoptosis by mediating the desuccinylation of CS by Huimin Cao, Dongsheng Wei, Dongsheng Wei, Han Li, Mei Zhao, Yixin Ma, Liang Kong, Guoyuan Sui, Lianqun Jia

“…In contrast, de-succinylation of CS at the K375 site significantly impaired mitochondrial function and ATP levels, increased ROS levels, and induced apoptosis in HepG2 cells.ConclusionSuccinylation of CS is crucial for maintaining mitochondrial function and promoting cell proliferation in liver cancer cells. …”
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