NPS-2143 suppresses malignant phenotypes of retinoblastoma cells involved in regulating NF-κB pathway by Cuiying Zhang, Tao Yu, Guanghua Sun, Miao Li

“…Abstract NPS-2143, as a CaSR allosteric antagonist, performs an important role in diverse cancers. However, the function and mechanism of NPS-2143 in human retinoblastoma have not been reported. …”
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Identification of fresh leaves of Anji White Tea: S-YOLOv10-ASI algorithm fusing asymptotic feature pyra-mid network. by Chunhua Yang, Wenxia Yuan, Qiang Zhao, Zejun Wang, Bowu Song, Xianqiu Dong, Yuandong Xiao, Shihao Zhang, Baijuan Wang

“…Intersection over Union (IoU) is used to optimize the loss function calculation. The slice-assisted super-reasoning algorithm is integrated to improve the recognition ability of YOLOv10 network for long-distance and small-target tea. …”
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miR-203 negatively regulates RLR-mediated antiviral immune response via targeting trim25 in rainbow trout (Oncorhynchus mykiss) by Yongjuan Li, Lu Zhao, Jinqiang Huang, Shenji Wu, Yujun Kang

“…Herein, we detected expression patterns of miR-203 and trim25 after rainbow trout infected with IHNV, and overexpressed and repressed miR-203 and trim25 to investigate their functions in vitro and in vivo. …”
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A Hybrid Path Planning Algorithm for Orchard Robots Based on an Improved D* Lite Algorithm by Quanjie Jiang, Yue Shen, Hui Liu, Zohaib Khan, Hao Sun, Yuxuan Huang

“…For global path planning, an enhanced D* Lite algorithm is used with a cost function that jointly considers centerline proximity, turning angle smoothness, and directional consistency. …”
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Deep metabolic profiling of immune cells by spectral flow cytometry—A comprehensive validation approach by Claire L. Wishart, Alanna G. Spiteri, Jian Tan, Claudio Counoupas, James A. Triccas, Laurence Macia, Nicholas J.C. King

“…This standardized approach reduces cost and experimental complexity, enabling researchers to elucidate how metabolism drives immune function across broader immunological and clinical contexts.…”
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Relaxation-exchange magnetic resonance imaging (REXI): a non-invasive imaging method for evaluating trans-barrier water exchange in the choroid plexus by Xuetao Wu, Qingping He, Yu Yin, Shuyuan Tan, Baogui Zhang, Weiyun Li, Yi-Cheng Hsu, Rong Xue, Ruiliang Bai

“…However, non-invasive imaging techniques to assess its function remain limited. This study was conducted to develop a novel, contrast-agent-free MRI technique, termed relaxation-exchange magnetic resonance imaging (REXI), for evaluating CP-CSF water transport, a potential biomarker of CP function. …”
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Oxytranscriptome of soybean seedlings under short-term cadmium treatment by Jarosław Gzyl, Marek Żywicki, Joanna Deckert, Mikołaj Lichocki, Yara Skafe, Jacek Bąk, Wojciech Roszka, Yang Shen, Xiaoli Sun, Jagna Chmielowska-Bąk

“…In turn, the lowly oxidized transcripts (LOTs) are involved in mitochondria functioning, response to stimuli and gibberellic acid (GA) metabolism.…”
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The effect of workplace environment on coal miners' gut microbiota in a mouse model by Lei Li, Lei Li, Mei Zhi, Mei Zhi, Siwei Wang, Siwei Wang, Siwei Wang, Jun Deng, Jun Deng, Qing Cai, Dayun Feng

“…After intervention with compound probiotics, the intestinal function of CEBS + Mix mice was improved and inflammation levels were reduced. …”
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CMOS-integrated organic neuromorphic imagers for high-resolution dual-modal imaging by Salihuojia Talanti, Kerui Fu, Xiaolong Zheng, Youzhi Shi, Yimei Tan, Chenxi Liu, Yanfei Liu, Ge Mu, Qun Hao, Kangkang Weng, Xin Tang

“…The fabricated imager allows in-sensor memorization (>18 min) and real-world spatiotemporal imaging with reduced computation resource, demonstrating its potential for industrial monitoring and motion detection.…”
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Investigation of the inhibitory effects of total flavonoids of litchi seed on Clonorchis sinensis-induced liver damage and fibrosis by Liuchun Luo, Liuchun Luo, Jilong Wang, Qiuchen Cheng, Zuochao Lu, Jiahui Lv, Suyu Xiao, Lili Tang, Shanshan He, Dengyu Liu, Zeli Tang, Qing Li, Tingzheng Zhan, Tingzheng Zhan, Tingzheng Zhan

“…The protein levels of α-SMA and collagen I was detected by Western blot.ResultsTFL improved liver function in C. sinensis-infected rats, as indicated by reduced levels of transaminases, bilirubin, and bile acids. …”
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Improving the conditions of regional hemodinamics of the eyes as a method of treatment in optic neuropathy at short-sightedness of high degree. by N. G. Zavgorodnyaya, O. O. Denisova, N. A. Vesnina, N. A. Kudinova- Savchenko

“…In the main group managed to reduce this figure by 14% in the control group - 10%. …”
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Tunable Emissions in Zero‐Dimensional (C6H5CH2NH3)3InBr6 Enabled by Controlled Structural Amorphization by Qian Li, Bin Xu, Xiaofan Xu, Yayun Wang, Zewei Quan

“…However, precise functionalization of organic moieties and controlled modulation of self‐trapped exciton (STE) emission from inorganic polyhedra remain challenging. …”
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Optimization of the Raman spectroscopic method for crystal orientation and residual stress of aluminum oxide by Miaoxia Xie, Chengyu Xiang, Xueliang Zeng, Xuesu Zhang, Linjie Zhang, Jiangtao Xiong

“…The measurement accuracies of crystal orientations when using different correction methods of light intensity were compared, and on that basis, a measurement system and a measurement method for the crystal orientation of 95% aluminum oxide (Al2O3) were established, which improved the accuracy and handleability of crystal orientation detection. Then, the number of Raman peak shifts needed for solving equations was reduced to three by studying the simplification method of stress fields, exploring the Raman selection method, and introducing the differential evolution algorithm. …”
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Proof-of-Concept of a Monopulse Antenna Architecture Enabling Radar Sensors in Unmanned Aircraft Collision Avoidance Systems for UAS in U-Space Airspaces by Javier Ruiz Alapont, Miguel Ferrando-Bataller, Juan V. Balbastre

“…In this ConOps, the Remain Well Clear (RWC) and CA functions are treated separately: RWC is the responsibility of ground-based U-space services, while CA is implemented as an airborne safety net using onboard equipment. …”
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Successful surgical procedure based on careful preoperative imaging for chronic idiopathic colonic pseudo-obstruction: a case report by Kosuke Yoshimura, Hiroki Ohge, Norimitsu Shimada, Shinnosuke Uegami, Yusuke Watadani, Ikki Nakashima, Toshinori Hirano, Hiroki Kitagawa, Yuki Kaiki, Shinya Takahashi

“…Careful imaging before surgery is important for detecting the extent of excision required. This will reduce the need for additional surgery due to symptom relapse in the remnant colon. …”
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HyenaCircle: a HyenaDNA-based pretrained large language model for long eccDNA prediction by Fuyu Li, Wenxiang Lu, Yunfei Bai

“…Long eccDNAs (typically 1–5 kb) pose detection challenges due to their large size, hindering functional studies. …”
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THE EFFECT OF THE DRUG MUMIJO ON THE PARAMETERS OF PLATELETS IN RESIDENTS OF AREAS WITH A CONSTANT COMBINED EFFECT OF NATURAL AND TECHNOGENIC IONIZING RADIATION by P.G. Kovalenko

“…Thus, the frequency of detection of persons with a reduced platelet content probably (Р<0.05) decreased, the limits of individual fluctuations of the platelet content shifted upwards to the limits of the norm, the average indicators probably increased (Р<0.05) with a tendency towards normalization. …”
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In vivo tracking of grape marc biomarkers, bioconversion, metabolic tracers, and microbiota modulation in swine fed a polyphenol-rich extract diet. by Aly Castillo, Maria Celeiro, Beatriz Martínez-Vallespín, Laura Rubio, Diego Gonzalez-Iglesias, Rocío Facorro, Carmen Garcia-Jares, Jürgen Zentek, Marta Lores

“…This was performed with the aim of testing the in vivo bioavailability of functional compounds, mainly phenolics, through the digestive system and excreta, together with the detection of bioconversion products associated with gut microbiota improvements. …”
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Optimal fuzzy-PID controller design for object tracking by Yaregal Limenih Melese, Girma Kassa Alitasb, Mequanent Degu Belete

“…It involves object representation, detection, and tracking. It becomes an important field of study due to the need in video surveillance, traffic monitoring, live sport video analysis and many other applications. …”
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Protective role of extracellular vesicles against oxidative DNA damage by Jordi Ribas-Maynou, Ana Parra, Pablo Martínez-Díaz, Camila Peres Rubio, Xiomara Lucas, Marc Yeste, Jordi Roca, Isabel Barranco

“…In addition, our in vitro study opens path to detect, localize and quantify the protective effects against oxidation of extracellular vesicles derived from different fluids, elucidating their function in physiopathological states.…”
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