PiRNA hsa_pir_018849 promotes the proliferation and invasion of osteosarcoma cells by regulating the stability of CCN5 mRNA by Jiale Huang, Saishuai Yang, Peng Liu, He Jiang, Zhiming Cui, Jiajia Chen

“…The expression levels of CCN5 were reduced by hsa_piR_018849. Hsa_piR_018849 reduced the stability of CCN5 by binding to the coding sequence (CDS) region of CCN5 mRNA. …”
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Can machine-learning algorithms improve upon classical palaeoenvironmental reconstruction models? by P. Sun, P. B. Holden, H. J. B. Birks, H. J. B. Birks

“…We considered three versions of the model: (1) a standard version of MEMLM, which uses only taxon abundance data; (2) MEMLMe, which uses only dimensionally reduced assemblage information, using a natural language-processing model (GloVe), to detect associations between taxa across the training data set; and (3) MEMLMc which incorporates both raw taxon abundance and dimensionally reduced summary (GloVe) data. …”
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Shotgun Quantitative Proteomic Analysis of Proteins Responding to Drought Stress in Brassica rapa L. (Inbred Line “Chiifu”) by Soon-Wook Kwon, Mijeong Kim, Hijin Kim, Joohyun Lee

“…The results of clustering analysis, gene ontology (GO) enrichment analysis, and analysis of composite expression profiles of functional categories for the differentially expressed proteins indicated that drought stress reduced the levels of proteins associated with photosynthesis and increased the levels of proteins involved in catabolic processes and stress responses. …”
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Tumor-derived exosomes and their application in cancer treatment by Afsaneh Javdani-Mallak, Seyed Javad Mowla, Mona Alibolandi

“…Researchers are now interested in tumor-derived exosomes as markers and potential novel vehicles for the delivery of therapeutics in cancer treatment since they exhibit different molecular profiles and biological functions. Methods PubMed, Scopus, and Google Scholar were methodically explored for articles estimating the dual functions of TDEs and their potential applications as new therapeutic targets and drug delivery vehicles for the transportation of anti-cancer drugs and immune-modulating compounds. …”
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Thermographic Insights into Degenerative Spinal Disorders: Evaluating the Diagnostic Potential of Digital Infrared Thermography Imaging by Sathish Muthu, Guna Pratheep Kalanchiam, Ashok Shyam

“…Degenerative spinal disorders are a growing concern, affecting millions worldwide and often leading to chronic pain, functional impairment, and reduced quality of life. …”
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Active Disturbance Rejection Vector Control for High-Power Asynchronous Motor to Suppress Measurement Noise by Xuesong ZHOU, Chenglong WANG, Youjie MA, Boning WU

“…The linear extended state observer (LESO) has the function of filtering the output signal of the system. …”
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Research on Rate Adaptation of Underwater Optical Communication with Joint Control of Photoelectric Domain by Yu Chen, Hongbing Qiu, Yanlong Li

“…In the optical domain, the incident light’s power is adaptively adjusted by controlling the transmittance of the liquid crystal light valve to reduce saturation distortion. In the electrical domain, the constellation distribution is optimized according to the desired probability mass function, and the modulation order is adjusted in real time by estimating the received signal-to-noise ratio of the link. …”
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Effect of Bazi Bushen Capsule on D‐Galactose‐Induced Human Endothelial Cell Senescence Through PI3K/Akt/eNOS Signaling Pathway by Lulu Yao, Fuyao Li, Jingnian Ni, Mingqing Wei, Ting Li, Jing Shi, Jinzhou Tian

“…ABSTRACT Objectives BaZi BuShen capsule (BZBS) is a Chinese herbal prescription with the function of nourishing the kidney, replenishing essence, and combating aging. …”
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Quality of life as a criterion for assessing the effectiveness of rehabilitation programs in patients with painful external genital endometriosis by E. Begovich, B. Baigalmaa, A. G. Solopova, V. O. Bitsadze, J. Kh. Khizroeva, E. A. Son, Sh. Kh. Zobaid, G. K. Bykovshchenko

“…The assessment of QoL (subjective) was performed using specialized questionnaires: visual analog scale (VAS), PainDETECT questionnaire, Endometriosis Health Profile-30 (EHP-30) questionnaire, Hospital Anxiety and Depression Scale (HADS), Female Sexual Function Index (FSFI). …”
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Evaluation of four KCNMA1 channelopathy variants on BK channel current under CaV1.2 activation by Ria L. Dinsdale, Andrea L. Meredith

“…The effects of gain-of-function (GOF) and loss-of-function (LOF) variants have been predominantly studied on BK channel currents evoked under steady-state voltage and Ca2+ conditions. …”
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Multimodal imaging of dark without pressure in high myopia reveals evidence that photoreceptor microscopic lesions may be reversible by Qingge Guo, Xiuxiu Jin, Xiaoyu Xin, Xiaohong Guo, Shuai Ming, Yuxiang Li, Bo Lei

“…Previous studies have concluded that DWP alone has no impact visual acuity, visual field, or other visual functions. This study aims to reveal the multimodal imaging manifestations of DWP in high myopia and to explore its impact on retinal function. …”
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Single-cell RNA sequencing reveals adrb1 as a sympathetic nerve-regulated immune checkpoint driving T cell exhaustion and impacting immunotherapy in esophageal squamous cell carcin... by Qun Li, Shuning Xu, Yulin Ren, Cheng Zhang, Ke Li, Ying Liu

“…Immunofluorescence confirmed colocalization of ADRB1 with T cells, and fluorescence-activated cell sorting (FACS) showed that ADRB1 expression was elevated alongside exhaustion markers, while immune function markers were reduced. CNV analysis highlighted malignant cells in the tumor microenvironment, and intercellular interaction analysis explored ADRB1+ T cells’ role in immune support. …”
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Screening for severe coronary stenosis in patients with apparently normal electrocardiograms based on deep learning by Zhengkai Xue, Shijia Geng, Shaohua Guo, Guanyu Mu, Bo Yu, Peng Wang, Sutao Hu, Deyun Zhang, Weilun Xu, Yanhong Liu, Lei Yang, Huayue Tao, Shenda Hong, Kangyin Chen

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Cohort profile: the Oxford Parkinson’s Disease Centre Discovery Cohort MRI substudy (OPDC-MRI) by Ricarda A L Menke, Michael Lawton, Thomas R Barber, Johannes C Klein, Clare Mackay, Konrad Szewczyk-Krolikowski, Michele T Hu, Michal Rolinski, Ludovica Griffanti, Samuel G Evetts, Faye Begeti, Marie Crabbe, Jane Rumbold, Richard Wade-Martins

“…The primary aim is to detect pathological changes in brain structure and function, and develop, together with the clinical data, biomarkers to stratify, predict and chart progression in early-stage Parkinson’s and at-risk individuals.Participants Participants are recruited from the OPDC Discovery Cohort, a prospective, longitudinal study. …”
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Thermodynamic Modeling of Hashtag Dynamics for Social Media Clustering: A Maxwell-Boltzmann Approach by Krishnan Batri, Rajermani Thinakaran, Bhuvana Jayabalan, L. Karthikeyan, S. Lakshmi, R. Sowrirajan, Sivaram Murugan

“…Our approach incorporates activation thresholds and power-law scaling behaviors through a temperature-dependent function, with Simple Moving Average techniques implemented to stabilize temperature estimation, mathematically reducing variance by a factor of 1/N. …”
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Machine learning for QoS and security enhancement of RPL in IoT-Enabled wireless sensors by Abubakar Wakili, Sara Bakkali, Ahmed El Hilali Alaoui

“…Simulations demonstrate that our framework significantly improves network throughput, reduces latency, and enhances packet delivery ratios while maintaining low jitter. …”
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Texture-preserving and information loss minimization method for infrared and visible image fusion by Qiyuan He, Yongdong Huang

“…TPFusion consists of the following key components: a multi-scale feature extraction module for enhancing the capability of capturing features; a texture enhancement module and contrast enhancement module, which helps to preserve fine-grained textures and extract salient contours and contrast information; a dual-attention fusion module for fusing the features extracted from the source images; an information content based loss function minimizing the feature discrepancy between the fused images and the source images and effectively reducing the information loss. …”
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Innovative Design and Performance Evaluation of Bionic Imprinting Toothed Wheel by Zhihong Zhang, Xiaoyang Wang, Jin Tong, Carr Stephen

“…Characteristics in the dung beetle’s foreleg end-tooth were extracted and studied by the edge detection technique. Then, this special outer contour curve was modeled by a nine-order polynomial function and used for the innovative design of imprinting the tooth’s cutting edge. …”
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Precoding Method Interference Management for Quasi-EVD Channel by Wei Duan, Wei Song, Sang Seob Song, Moon Ho Lee

“…Also, in our proposed CD-BD IA algorithm, the relaying function is made use to restructure the quasieigenvalue decomposition (quasi-EVD) equivalent channel. …”
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Current trends in neurocritical care: a comprehensive review by Vinothini Murugaiyan, Kingston Samraj Kirubakaran Jebaraj, Srinivas Kalaiselvan

“…Continuous neuromonitoring using tools like electroencephalogram and intracranial pressure monitoring offers real-time data on brain function, aiding in the early detection of complications. …”
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