Role of BDNF-TrkB signaling pathway in early-life cadmium exposure induced cognitive dysfunction in mice by Yan SHI, Siqi YANG, Yougang WANG, Qiumei WU, Jinquan LI

“…The cadmium content in brain was detected and the learning and memory ability was tested by Y maze and Morris water maze to evaluate cognitive function of offspring mice. …”
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An Integrated Approach to the Design of Wireless Sensor Networks for Structural Health Monitoring by Fabio Federici, Fabio Graziosi, Marco Faccio, Andrea Colarieti, Vincenzo Gattulli, Marco Lepidi, Francesco Potenza

“…In this paper, possible benefits and critical issues related with the use of Wireless Sensor Networks for structural monitoring are analysed, specifically addressing network design strategies oriented to the damage detection problem. A global cost function is defined and used for the definition of possible design methodologies. …”
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The differential expression of MAGI2 in glomerulopathies and its application as a molecular discriminator of podocytopathies by Florian Siegerist, Eleonora Hay, Elke Hammer, Anna Iervolino, Claudia Weber, Juan Saydou Dikou, Eleni Stamellou, Linus Butt, Thomas Benzing, Thorsten Wiech, Paul T. Brinkötter, Uwe Zimmerman, Giovambattista Capasso, Christos Chatziantoniou, Christos E. Chadjichristos, Tobias B. Huber, Uwe Völker, Maximilian Schindler, Nicole Endlich

“…This downregulation was also conserved in a zebrafish model of focal and segmental glomerulosclerosis (FSGS), and the podocyte-specific MAGI2 ortholog Magi2a was reduced post podocyte injury. CRISPR/Cas9-generated zebrafish mutants for magi2a exhibited marked glomerular filtration barrier defects and downregulation of nephrin, underscoring MAGI2's critical role in podocyte function. …”
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Assessing the cumulative effects of nearshore habitat restoration actions for multiple populations of juvenile salmon in Whidbey Basin, Washington: foundation and approach for synt... by Kathryn L. Sobocinski, Michael LeMoine, Joshua W. Chamberlin, Letitia Conway-Cranos, Annelise Del Rio, Heida L. Diefenderfer, Heida L. Diefenderfer, Correigh M. Greene, Jason Hall, Gary E. Johnson, Ronald M. Thom, Elene Trujillo, Todd Zackey

“…Ecosystem restoration is a common tool for re-establishing ecosystem processes, structures, and functions to improve biodiversity and services in coastal and estuarine ecosystems. …”
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Species-level enumeration of low-concentration lactic acid bacteria in breast milk by Yue Sun, Qiming Li, Mengling Hu, You Wu, Yunchao Wa, Hai Lu, Shilong Jiang, Hui Wang, Qiaosi Wei, Yujun Huang, Ruixia Gu, Chenchen Zhang

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Ischemic postconditioning protects against acute kidney injury after limb ischemia reperfusion by regulating HMGB1 release and autophagy by Zhongdi Liu, Yifan Chen, Zhe Du, Fengxue Zhu, Wei Huang

“…The levels of kidney function parameters, serum inflammatory factors, and autophagy markers were detected. …”
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Experimental Study on the Inhibition of RANKL-Induced Osteoclast Differentiation In Vitro by Metformin Hydrochloride by Zhang Chen, Liu Zige, Yeow Sai Kiang, Chen Desheng

“…Real-time fluorescence quantitative PCR was performed to detect the expression of Cathepsin K, osteoclast associated receptor (OSCAR), and TRAP, and the effect of Met on Mitogen-activated protein kinases (MAPK) signaling pathway was detected by Western blot. …”
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The possible impact of pre-transfusion laboratory interference by Luís Moura, Liliana Fonseca, Emanuel Rodrigues, Rui Lobo, Arnaldo Brito, Mariana Costa

“… Introduction: Pre-transfusion tests allow the detection of clinically significant antibodies and the prior compatibility of units to be transfused. …”
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Methylprednisolone effects on serum biochemical factors (CRP, PCT, IL-6, TNF-a) in viral pneumonia by Zeng Hongping, Zhu Qi, Bai Shaoyu, Liu Jie, Ren Dengjie, Chen Xin

“…C-reactive protein (CRP), procalcitonin (PCT), and interleukin-6 (IL-6) were detected. Pulmonary function parameters were assessed using a pulmonary function testing device. …”
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An Inverse Modeling Multi-Objective Optimization Technique Based on Incremental Learning and Fuzzy Clustering by Gadallah Mohamed Abd Elaziz, Yasmine Abouelseoud, Sara H. Kamel

“…Extensive simulations on various benchmark problems show that the proposed algorithm drastically reduces the number of function evaluations required to reach an optimal solution compared to existing methods. …”
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A novel rapid and reproducible flow cytometric method for optimization of transfection efficiency in cells. by Stefanie Homann, Christian Hofmann, Aleksandr M Gorin, Huy Cong Xuan Nguyen, Diana Huynh, Phillip Hamid, Neil Maithel, Vahe Yacoubian, Wenli Mu, Athanasios Kossyvakis, Shubhendu Sen Roy, Otto Orlean Yang, Theodoros Kelesidis

“…One of the biggest challenges to investigate the protein function and interaction in gene therapy studies is to have reliable monospecific detection reagents, particularly antibodies, for all human gene products. …”
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Assessing Locomotive Syndrome Through Instrumented Five-Time Sit-to-Stand Test and Machine Learning by Iman Hosseini, Maryam Ghahramani

“…Locomotive syndrome (LS) refers to a condition where individuals face challenges in performing activities of daily living. Early detection of such deterioration is crucial to reduce the need for nursing care. …”
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Robust DOA Estimation via a Deep Learning Framework with Joint Spatial–Temporal Information Fusion by Yonghong Zhao, Xiumei Fan, Jisong Liu

“…A post-processing strategy based on peak detection and quadratic interpolation is also employed to refine DOA estimations and reduce quantization errors. …”
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Identification of Coal Mine Infrastructure Facilities with Inefficient Power Consumption by Belyaevsky R.V., Ahmetgareev A.R.

“…The analysis was conducted using Mathcad 15, which allows the calculation of confidence intervals via the inverse Laplace function. The practical significance of this research lies in reducing energy audit costs by prioritizing inspections of problematic facilities. …”
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Epidemiology of kidney disease in patients with COVID-19 by N. G. Kulchenko

“…Early detection and correction of violations of filtration and excretory function of the kidneys, including adequate hemodynamic support and restriction of nephrotoxic drugs, can improve the prognosis of recovery of a patient with COVID-19.…”
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Pathogenetic substantiation of a differential approach to the treatment of endometrial hyperplasia in women with abdominal obesity by Nataliia Mokrianyn

“…According to the Global Cancer Observatory 2019, endometrial cancer affects 382,000 women worldwide per year. With timely detection and treatment of endometrial hyperplasia and modification of the factors that lead to excessive proliferation of the internal lining of the uterus, it will be possible to reduce the incidence and preserve the fertility of women of reproductive age. …”
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DANNET: deep attention neural network for efficient ear identification in biometrics by Deepthy Mary Alex, Kalpana Chowdary M., Hanan Abdullah Mengash, Venkata Dasu M., Natalia Kryvinska, Chinna Babu J., Ajmeera Kiran

“…This shift has highlighted the need for reliable biometric systems that can function effectively even when facial features are partially obscured. …”
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Review of Pre-processing Techniques for Meteorological Satellite Data Assimilation in Numerical Prediction by Ma Gang, Huang Jing, Gong Xinya, Xi Shuang, Xue Lei, Li Juan, Zhang Peng, Gong Jiandong

“…In the development of satellite data assimilation pre-processing technology, reprocessing of pre-processed satellite data by using a unified data format, expanding the processing for satellite imagery and active detection data, and front-loading a part of satellite data assimilation quality control function into data assimilation pre-processing are important trends in the development of future assimilation pre-processing technology for Fengyun satellite data.…”
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Application of Chelex-100 and SPR-IDA Resin in Combination with the Optimized Beam Deflection Spectrometry for High-Sensitivity Determination of Iron Species in Sediment Porewater by Hanna Budasheva, Mohanachandran Nair Sindhu Swapna, Arne Bratkič, Dorota Korte

“…In this work, photothermal beam deflection spectrometry (BDS), combined with a passive sampling technique of diffusive gradients in thin film (DGT), is optimized to improve the method’s sensitivity. The limit of detection (LOD) is then reduced by a factor of 2 (to the value of 20 nM). …”
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Funding the future: safeguarding pediatric health equity through CMS and CHIP by Carlie N. Myers, Meera Rao, Rishiraj Bandi, Sebastian Densley, Daniella Diaz, Michelle Knecht, Lea Sacca

“…Across these studies, common themes emerged: community engagement, cross-sector collaboration, and expanded insurance access improved outcomes and reduced costs. Medicaid expansion reduced in-hospital mortality and improved access to rehabilitative care, while CHIP increased preventive service use among near-poor children. …”
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