Effect of phototherapy on event-related potentials in patients with post-stroke depression through serum tetrahydrobiopterin level intervention: a clinical study by Bingchuan Xie, Zhenguo Wu, Zixuan Zhou, Wenting Lu, Lin Liu, Lizhuang Zhang

“…Conclusions Phototherapy positively influenced BH4 levels, improved evoked potentials, alleviated depressive symptoms, enhanced cognitive function, and reduced inflammation in post-stroke depression patients.…”
Get full text

Subclinical Myocardial Dysfunction in Pediatric and Adolescent Celiac Disease Patients: A Systematic Review and Meta-Analysis by Elpida Emmanouilidou-Fotoulaki, Maria Kavga, Michail Delis, Evangelia Farmaki, Charalampos Agakidis, Kyriaki Papadopoulou-Legbelou

“…Our results showed a trend toward reduced myocardial function in all echocardiographic parameters (conventional and advanced), with statistical significance in fractional shortening and the myocardial performance index. …”
Get full text

Research on Dynamic Performance of Locomotive Wheelset Driving Unitwith Gear Teeth Cracks by FAN Jiafeng, DENG Tiesong, LI Fuzhong, SU Zhaoyi

“…Moreover, without the inner FE (force element) gear-pair of SIMPACK, thegear-pair meshing model was realized through the methods of moved markers, function expressions, input functions and so on. The resultsshowed that the difference between gear-pair meshing model and FE gear-pair was smaller than 10 percent; The meshing vibration ofgear-pair performed the time-varying character of the meshing stiffness; The reference circle crack would have a time-domain impact onthe dynamic performance of wheelset driving unit; Through the basic frequency of the smaller gear which was exhibited by the wheelsetdriving unit, the impact could be detected through frequency-domain method when the crack reached to some certain depth (i.e. thestiffness reduced to some certain value). …”
Get full text

Extracellular matrix and left atrial remodeling in patients with ischemic chronic heart failure and renal dysfunction by D. A. Lashkul

“…Collagen metabolism markers (MMP-9, TIMP-1, РІСР), cystatin C activity were studied in 336 patients with ischemic chronic heart failure using ELISA method. Structural and functional parameters of the heart were detected by echocardiography. …”
Get full text

Case Report: Sequential treatment with rituximab and belimumab in a pediatric patient of type 1 diabetes mellitus complicated with systemic lupus erythematosus by Fangfang Li, Yuci Zhang, Jing Yin, Linsheng Zhao, Chongwei Li

“…However, due to the prolonged disease course of T1DM, the pancreatic cell function was not reversed.…”
Get full text

DNMT3a-Mediated Enterocyte Barrier Dysfunction Contributes to Ulcerative Colitis via Facilitating the Interaction of Enterocytes and B Cells by Bo Cheng, Ai-mei Rong, Wenlu Li, Xiuqian Bi, Xinguang Qiu

“…The primary intestinal epithelial cells (IECs) were isolated and treated with lipopolysaccharide (LPS) to establish an in vitro inflammatory model. We detected mouse clinical symptoms, histopathological damage, enterocyte barrier function, B cell differentiation, DNA methylation level, and cytokine production. …”
Get full text

Mutual interaction between motor cortex activation and pain in fibromyalgia: EEG-fNIRS study. by Eleonora Gentile, Antonio Brunetti, Katia Ricci, Marianna Delussi, Vitoantonio Bevilacqua, Marina de Tommaso

“…Functional near-infrared spectroscopy is a portable and optical method to detect cortical metabolic changes. …”
Get full text

Selective Retention of an Inactive Allele of the DKK2 Tumor Suppressor Gene in Hepatocellular Carcinoma. by Yung-Feng Lin, Ling-Hui Li, Chih-Hung Lin, Mei-Hua Tsou, Ming-Tai Kiffer Chuang, Keh-Ming Wu, Tsai-Lien Liao, Jian-Chiuan Li, Wei-Jie Wang, Angela Tomita, Beverly Tomita, Shiu-Feng Huang, Shih-Feng Tsai

“…In an effort to identify the functional alleles associated with hepatocellular carcinoma (HCC), we investigated 152 genes found in the 4q21-25 region that exhibited loss of heterozygosity (LOH). …”
Get full text

Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice by Shiyan Wang, Ye Zhou, Yucheng Wu, Yali Lang, Yajun Mao, Guoyuan Pan, Zhenzhen Gao

“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).ConclusionAerobic exercise enhances memory and learning abilities, improves cognitive function, and reduces the oxidative stress levels in the hippocampus of AD mice, which involves in the activation of Keap1/Nrf2/GPX4 pathway.…”
Get full text

A Ship Underwater Radiated Noise Prediction Method Based on Semi-Supervised Ensemble Learning by Xin Huang, Rongwu Xu, Ruibiao Li

“…Accurate prediction of ship underwater radiated noise (URN) during navigation is critical for evaluating acoustic stealth performance and analyzing detection risks. However, the labeled data available for the training of URN prediction model is limited. …”
Get full text

Evaluation of additional points in the 24-2C visual field test in pre-perimetric glaucoma by Gökhan Çelik, Tuncay Karaçocuk, Furkan Çiftci

“…Conclusion: Although no glaucomatous change was observed in the VF in patients with PPG, these patients showed reduced sensitivity of the additional points. The reduced sensitivity of the additional points in the 24-2C VF test may reflect early macular functional alterations that correlate with structural damage during the pre-perimetric period.…”
Get full text

Mucin adsorbed by E. coli can affect neutrophil activation in vitro by Elena Mikhalchik, Nadezhda Balabushevich, Tatiana Vakhrusheva, Alexey Sokolov, Julia Baykova, Daria Rakitina, Petr Scherbakov, Sergey Gusev, Alexander Gusev, Zaira Kharaeva, Olga Bukato, Olga Pobeguts

“…Activation was evaluated based on the detection of reactive oxygen species production by a chemiluminescent reaction (ChL), observation of morphological alterations in neutrophils and detection of exocytosis of myeloperoxidase and lactoferrin. …”
Get full text

An Observational Study on the Reversibility of Left Ventricular Diastolic Dysfunction, Impaired Left Ventricular Ejection Fraction and Abnormal Left Ventricular Mass with Levothyro... by Abhirup Chatterjee, Anupam Mandal, Sattik Siddhanta, Rajdip Sen

“…Objectives: To find out the change in left ventricular systolic and diastolic function as well as left ventricular mass index (LVMI) with treatment of primary hypothyroidism with levothyroxine replacement in 6 months time frame and to detect reversibility, if present at all, of E/E´(E—early transmitral diastolic velocity, E´– tissue Doppler early diastolic velocity), left ventricular ejection fraction (LVEF) and LVMI after patient become biochemically euthyroid. …”
Get full text

Simultaneous removal and optical determination of mercury ions by constructing fluorescent recombinant T. thermophila SB210 strains by Shu-Hui Zhao, Kai-Kang Hu, Jie Xiong, Jia-Wei Tu, Wei Miao

“…Removing and monitoring Hg2+ ions in the pollution sources based on microorganisms have the advantages of low cost and convenience. To reduce the harm of Hg2+ ions to humans and ecosystems in the environment, it is considered very meaningful to establish a biological treatment method using protozoa to simultaneously detect and remove Hg2+ ions in polluted water. …”
Get full text

Effect of Systematic Errors on Building Component Sound Insulation Measurements Using Near-Field Acoustic Holography by Wei Xiong, Wuying Chen, Zhixin Li, Heyu Zhu, Xueqiang Wang

“…However, based on Green’s function, the microphone array’s inherent amplitude and phase mismatch errors will exponentially amplify the sound field inversion process, significantly reducing the measurement accuracy. …”
Get full text

Research on Buckwheat Weed Recognition in Multispectral UAV Images Based on MSU-Net by Jinlong Wu, Xin Wu, Ronghui Miao

“…The neuron death caused by the original ReLU activation function may lead to misidentification, so it was replaced by the Swish function to improve the adaptability to complex inputs. …”
Get full text

肉苁蓉总苷经PI3K-Akt信号通路对大鼠脑缺血再灌注损伤的神经保护作用及机制研究 Neuroprotective Effect and Mechanism of Glycosides of Cistanche on Cerebral Ischemia-Reperfusion Injury in Rats Based on PI3K-Akt Signal... by 王璐1，张士滨2，吕雪2，杨占君3，贾建新3，吴丽娥1 (WANG Lu1, ZHANG Shibin2, LYU Xue2, YANG Zhanjun3, JIA Jianxin3, WU Li’e1 )

“…Results Compared with the sham group, the CIRI model rats exhibited severe neurological deficit symptoms, increased neurological function scores (P<0.05), reduced motor function, enlarged cerebral infarction area, increased apoptotic cells, and elevated expression of pro-apoptotic factors B-cell lymphoma-2 (Bcl-2) associated X protein (Bax) and cytochrome C (CytC) (P<0.05). …”
Get full text

Targeting MAD2B as a strategy for ischemic stroke therapy by Lijing Zhang, Hengzhen Cui, Wandi Hu, Xianfang Meng, Chun Zhang

“…MAD2B is an inhibitor of Cdh1/APC, and loss of Cdh1/APC function in mature neurons increases ROCK2 activity, leading to changes in synaptic plasticity and memory loss in mouse neurons. …”
Get full text

The biomarker potential of circPOLD1 and its binding protein YBX1 in cervical carcinogenesis by Lu Zhao, Xin Chen, Yanan Zhang, Yixuan Cen, Tingjia Zhu, Lingfang Wang, Lili Xia, Yang Li, Xiaodong Cheng, Xing Xie, Weiguo Lu, Junfen Xu

“…Mechanistically, circPOLD1 functioned as an oncogene by binding to and phosphorylating YBX1, activating the AKT/mTOR/HIF-1α pathway to enhance glycolysis-driven tumorigenesis. …”
Get full text

Analysis of dynamic network reconfiguration in HIV patients with cognitive impairment based multilayer network by Xingyuan Jiang, Juming Ma, Chuanke Hou, Hongjun Li

“…Our study aims to evaluate changes in the dynamic activity patterns of functional brain communities in the early stages of HIV infection by comparing time-varying multilayer network metrics. …”
Get full text