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1561
Investigation of PANoptosis pathway in age-related macular degeneration triggered by Aβ1-40
Published 2025-04-01“…Enzyme-linked immunosorbent assay (ELISA) was used to detect the levels of cytokines in cell supernatants, mouse orbital serum, and human plasma to evaluate the severity of inflammation. …”
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1562
Serum exosomal microRNA profiling reveals a down-regulation of hsa-miR-124-3p in patients with severe acne
Published 2025-06-01“…The DAVID database was used to enrich GO function and KEGG pathway analysis of target genes. …”
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1563
Ethyl Acetate Extract of Elsholtzia bodinieri Vaniot Attenuates Oxidative Stress in ALI Mice
Published 2025-06-01“…Different doses of EBEE were feed into ALI mice in vivo (600 mg/kg bw, 200 mg/kg bw) and .RAW 264.7 cells (100 μg/mL, 25 μg/mL) in vitro to evaluate the protection function. Western Blot, immunofluorescence and biochemical factor detection were used to measure the levels of oxidative stress associated factors, and gut microbiota analysis examined the gut microbiota in mice.Results: EBEE, which contained a total of 1374 components, was identified as the most active against oxidative stress. …”
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1564
Decoding canine parvovirus: biomarkers for diagnosis and advances in vaccine development to address emerging challenges
Published 2025-08-01“…Early diagnosis is crucial for timely treatment, but traditional detection methods like hemagglutination inhibition tests often lead to misdiagnosis, delaying therapy. …”
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1565
Biocompatible bright orange emissive carbon dots: Multifunctional nanoprobes for highly specific sensing toxic Cr(VI) ions and mitochondrial targeting cancer cell imaging
Published 2024-12-01“…In addition, they were shown to function as a mitochondria-targeting nanoprobe in human cancer cells (ME 180 cells and Hela cells) for cell imaging. …”
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1566
Comparison of Efficacy and Safety Outcomes of Different Doses Schedules of Thalidomide for Treating Moderate-to-Severe β-Thalassemia Patients
Published 2024-11-01“…Hemolysis effects were assessed via total bilirubin and indirect bilirubin level measurements. Thrombosis detection was performed using ultrasound examinations of deep vein vessels in the upper and lower extremities. …”
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1567
A novel approach to regulate glucose uptake in an anaplastic thyroid cancer cell line
Published 2025-01-01“…Aims and background: Curcumin’s function in affecting cancer metabolic reprogramming remains poorly understood. …”
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1568
Autobiographical memory in Alzheimer’s disease: a systematic review
Published 2025-06-01“…These deficits were characterized by reduced memory specificity across all life periods, with patients showing a tendency toward overgeneralization. …”
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1569
Testosterone Deficiency and Lipid Dysregulation in Individuals with Coexisting Hypothyroidism and Type 2 Diabetes: Clinical and Metabolic Implications
Published 2025-05-01“…Lipid profile analysis revealed significantly higher total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglyceride (TG) levels in the diabetic and hypothyroid diabetic groups, with no major differences in high-density lipoprotein cholesterol levels. Thyroid function tests indicated elevated thyroid-stimulating hormone and reduced free triiodothyronine and free thyroxine in hypothyroid and hypothyroid diabetic individuals. …”
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1570
Association of estimated glucose disposal rate with chronic kidney disease: comparative analysis against traditional insulin resistance indices
Published 2025-07-01“…Additionally, the performance of these indices was evaluated using receiver operating characteristic (ROC) curve analysis.ResultsElevated levels of the eGDR were significantly correlated with improved kidney function and a reduced prevalence of chronic kidney disease (CKD) and albuminuria. …”
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1571
ASIC Current-Reuse Amplifier With MEMS Delta-E Magnetic Field Sensors
Published 2024-01-01“…An application specific integrated circuit (ASIC) and a custom-made microelectromechanical system (MEMS) sensor are presented, designed to function together as a sensor system for measuring low amplitude low frequency magnetic fields. …”
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1572
Antidepressant effects and mechanisms of Wuhua herbal tea in a rat model of chronic unpredictable mild stress
Published 2025-07-01“…It also restores BDNF-CREB pathway function, reducing depressive symptoms.…”
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1573
Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis.
Published 2016-01-01“…The developmental defects in the Osr1+/-Wt1+/- mouse embryos were detected as early as E10.5, during specification of the metanephric mesenchyme, with the Osr1+/-Wt1+/- mouse embryos exhibiting significantly reduced Pax2-positive and Six2-positive nephron progenitor cells. …”
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1574
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma
Published 2022-01-01“…QRT-PCR, Western blot, flow cytometry, and CCK-8 were used to detect the function of Eca-109 and KYSE-510 cells. …”
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1575
HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread
Published 2025-04-01“…Virus cell-to-cell spread efficiency was measured through flow cytometry-based detection of p24, while nutrient uptake assays and mitotracker dye detection served as surrogate markers for T-cell metabolism and mitochondrial function. …”
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1576
Solar Photovoltaic Diagnostic System with Logic Verification and Integrated Circuit Design for Fabrication
Published 2025-05-01“…Once its functionality was confirmed, an ASIC design was proposed for mass production, offering a significantly lower implementation cost and reduced hardware complexity than prior methods. …”
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1577
An AI-Based Open-Source Software for <i>Varroa</i> Mite Fall Analysis in Honeybee Colonies
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1578
PCBP2 as an intrinsic agi ng factor regulates the senescence of hBMSCs through the ROS-FGF2 signaling axis
Published 2025-03-01“…Methods: Unlabeled quantitative proteomics were performed to show differentially expressed proteins in the replicative senescent human bone marrow mesenchymal stromal cells (RS-hBMSCs). ROS and FGF2 were detected in the loss-and-gain cell function experiments of PCBP2. …”
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1579
Effects of Electroacupuncture on Syt3 and GluA2 in Rats With Limb Spasms After Intracerebral Hemorrhage
Published 2025-03-01“…Results Compared to the ICH group, rats in the EA group showed reduced muscle tone in the left limbs and significant improvement in neurological deficits and motor function. …”
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1580
lncRNA OIP5-AS1 Suppresses Cell Proliferation and Invasion of Endometrial Cancer by Regulating PTEN/AKT via Sponging miR-200c-3p
Published 2021-01-01“…In the present study, we demonstrated that long noncoding RNA OIP5-AS1 was significantly reduced in EC tissue compared with normal tissue. …”
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