Late Presentation of Isolated Persistent Left Superior Vena Cava with Absent Right Superior Vena Cava Manifesting as Heart Failure: A Case Report by Ahmed SA, Dahir OF, Abdi AE, Adan AS, Abdi IA, Waberi MM, Mohamud MA, Fujeyra AMH, Ali AA, Ahmed MA, Adan Ali BA, Hassan MS, Aksu F, Mukhtar MS, Ibrahim IG, Hassan MO

“…In rare cases, it may contribute to hemodynamic disturbances and arrhythmias, potentially leading to heart failure, especially when associated with other cardiac anomalies or conduction abnormalities.Case Presentation: We report the case of a 45-year-old male who presented with progressive symptoms of heart failure, including dyspnea, fatigue, and reduced exercise tolerance. Initial workup revealed an unexplained dilated coronary sinus and reduced left ventricular function with dilated heart chambers. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…In MI mice, expression trends of four hub MitoDEGs (Cox5b, Ndufa2, Ndufs6, and Uqcr11) were consistent with the bioinformatics results, and their downregulation was associated with reduced cardiac function. CD86 and apoptosis-related proteins (BAX/BCL-2 and cleaved caspase-3) were markedly elevated in MI groups.ConclusionThese findings suggest that Cox5b, Ndufa2, Ndufs6, and Uqcr11 act as core regulatory molecules in immunometabolism during MI, providing new insights into its pathogenesis and diagnosis.…”
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Chlorogenic acid alleviates the intestinal barrier dysfunction and intestinal microbiota disorder induced by cisplatin by Ruiqi Tian, Yinchuan Ding, Shijie Zhang, Min Li, Yiran Wang, Qi Wu, Huanhuan Ding, Chengjie Song, Ce Shi, Min Xue

“…The inflammation factor of IL-6, IL-1β, and TNF-α in colonic tissue and serum were detected, respectively. To explore the protection of chlorogenic acid on mucosal barrier’s integrity, we also detected the fecal LPS and the expression of occludin and ZO-1 proteins in colon tissue. …”
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The transcription factor Ste12 mediates the regulatory role of the Tmk1 MAP kinase in mycoparasitism and vegetative hyphal fusion in the filamentous fungus Trichoderma atroviride. by Sabine Gruber, Susanne Zeilinger

“…Here we analyzed the functions of the T. atroviride Ste12 transcription factor whose orthologue in yeast is targeted by the Fus3 and Kss1 MAP kinases. …”
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How Life Experience Shapes Cognitive Control Strategies: The Case of Air Traffic Control Training. by Sandra Arbula, Mariagrazia Capizzi, Nicoletta Lombardo, Antonino Vallesi

“…These results indicate a training-induced change in reactive control, which is described as a transient process in charge of stimulus-driven task detection and resolution. This experience-based enhancement of reactive control strategy denotes how cognitive control and executive functions in general can be shaped by real-life training and underlines the importance of experience in explaining inter-individual variability in cognitive functioning.…”
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Cardiac toxicity in children and adolescents with Hodgkin lymphoma after chemoradiotherapy by R. I. Feoktistov, O. A. Schurova, J. G. Abugova, J. Yu. Dyakonova, O. V. Makarova, N. V. Myakova, N. B. Senyakovich, E. V. Samochatova

“…Reduced contractility was detected in 5 (11.9 %) children after chemoradiotherapy, that requires cardiac function monitoring and cardiologist’s consultation.…”
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Toward Aerosol-Aware Thermal Infrared Radiance Data Assimilation by Shih-Wei Wei, Cheng-Hsuan (Sarah) Lu, Emily Liu, Andrew Collard, Benjamin Johnson, Cheng Dang, Patrick Stegmann

“…The DA framework consists of the detection of hazy-sky pixels and an observation error model as the function of the aerosol effect. …”
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Abstract 149: Metabolic Neuroimaging in the Assessment of Cardiovascular Risk: A Regional FDG‐PET Analysis by Robert C. Subtirelu, Eric M. Teichner, Yvonne Su, Thomas Werner, Abass Alavi, Poul Flemming Høilund‐Carlsen, Mona‐Elisabeth Revheim

“…This study analyzed regional glucose metabolism in individuals with known CVD risk factors. The detection of such metabolic changes could assist in determining the necessity and timing of vascular interventions, such as carotid endarterectomy (CEA) or carotid artery angioplasty with stenting (CAS), contributing to improved patient outcomes and reduced postoperative complications. …”
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Cyanidin-3-<i>O</i>-Glucoside Mitigates Amyloid-Beta (1–42)-Induced Apoptosis in SH-SY5Y Cells by Regulating Ca²⁺ Homeostasis and Inhibiting Mitochondrial Dysfunction by Chao Ma, Yu Nie, Donglei Zhang, Lulu Ran, Su Xu, Xun Ran, Junya Huang, Lingshuai Meng

“…Results: We found that Cyanidin-3-<i>O</i>-glucoside could downregulate the expression of cytochrome c, caspase 9, caspase 3, and other genes and proteins, which consequently reduced the rate of apoptosis. Additionally, it could upregulate Bcl-2 gene and protein expression, downregulate Bax gene and protein expression, regulate mitochondrial membrane permeability and calcium-release channels, reduce calcium influx into mitochondria, maintain intracellular calcium ion levels, reduce intracellular levels of reactive oxygen species and increase ATP levels, maintain the mitochondrial membrane potential at a normal level, maintain normal mitochondrial functioning, and prevent apoptosis. …”
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RL-Cervix.Net: A Hybrid Lightweight Model Integrating Reinforcement Learning for Cervical Cell Classification by Shakhnoza Muksimova, Sabina Umirzakova, Jushkin Baltayev, Young-Im Cho

“…A novel application of RL for dynamic feature refinement and adjustment based on reward functions was employed to optimize the detection capabilities of the model. …”
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An Artificial Neural Network Developed in MATLAB-Simulink for Reconstruction a Distorted Secondary Current Waveform. Part 1 by Yu. V. Rumiantsev, F. A. Romaniuk

“…A possible application of the аrtificial neural networks for the relay protection purposes is the fault occurrence detection and its type identification, current transformer secondary current waveform distortion restoration due to its saturation up to its true value, detection the distorted and undistorted sections of the current transformer secondary current waveform during its saturation, primary power equipment abnormal operating modes detection, for example, power transformer magnetizing current inrush. …”
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SS-31: A promising therapeutic agent against bleomycin-induced pulmonary fibrosis in Mice. by Quankuan Gu, Yunlong Wang, Haichao Zhang, Wei Yang, Xianglin Meng, Mingyan Zhao

“…Electron microscopy and ATP detection further suggested that SS-31 might help protect mitochondrial structure and function. …”
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The effect of mild to moderate knee osteoarthritis on gait and three-dimensional biomechanical alterations by Jing Pan, Zhonghao Xie, Huifang Shen, Zhiguan Huang, Xiaohui Zhang, Bagen Liao

“…BackgroundKnee Osteoarthritis (KOA) is a prevalent chronic degenerative joint disease, particularly among the elderly, leading to pain, stiffness, and diminished functionality. The progression of KOA is often associated with significant changes in gait and biomechanics, yet detailed investigations of these changes—especially in early to moderate stages—remain limited. …”
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Near-Infrared Imaging of Glymphatic Clearance in a Pre-Clinical Model of Repetitive Closed Head Traumatic Brain Injury by Eleftheria Michalaki, Alexis N. Pulliam, Pooja M. Datta Roy, J. Brandon Dixon, Michelle C. LaPlaca

“…These data indicate that TBI disrupts normal brain efflux kinetics and reduces glymphatic drainage to the CLNs, demonstrating that restoring glymphatic function may be a promising therapeutic target.…”
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Cardiovascular evaluation in children with acute moderate to severe malnutrition by Ahmed Behairy, Fatma AlZahraa Mostafa, Rodina Sobhy, Bavly Ghattas, Noha Ali, Christine G. Salama

“…By conventional echo, no myocardial systolic function could be detected. A significantly lower global longitudinal strain (GLS) by strain imaging was found in the cases in addition to reduced muscle mass. …”
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THE CHANGES IN TOTAL PROTEIN LEVEL IN BLOOD SERUM AND ORAL FLUID OF THE PATIENTS DURING THE TREATMENT OF GENERALIZED PERIODONTITIS COMBINED WITH CHRONIC LIVER DISEASES by R.S. Kashivska, М.М. Rozhko, G.М. Melnychuk

“…The increasing of TP level in blood serum of patients with GP after the complex treatment apparently is due to the influence of the applied hepatoprotector Glutargin which contributed to the restoration of the protein-synthesizing liver function. Conclusion. Multidirectional changes of TP level in biological fluids were detected in patients with GP. …”
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Gut microbiota dysbiosis exacerbates heart failure by the LPS-TLR4/NF-κB signalling axis: mechanistic insights and therapeutic potential of TLR4 inhibition by Chunlei Zhang, Xiaodong Teng, Qiuhang Cao, Yanyan Deng, Mo Yang, Lei Wang, Daorong Rui, Xiu Ling, Cao Wei, Yue Chen, Dasheng Lu, Hongxiang Zhang

“…Abstract Objective This study aimed to investigate the associations between gut microbiota dysbiosis and alterations in cardiac function and to elucidate the underlying molecular mechanisms involved. …”
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Effect of Baicalein on Cognitive Impairment in Diabetes Mellitus with Cerebral Small Vessel Disease by Li ZHOU, Zhengqi LU, Xiaoming YE, Wanxin YANG, Zhisheng WEI, Yi KONG, Xuming HUANG

“…After the stable models of DM with CSVD were established, cognitive function scores of all rats were evaluated by Morris water maze test, and the levels of acetylcholine (Ach) and acetylcholinesterase (AchE) in brain were assessed to evaluate the protective effects of baicalein.Results:Morris water maze test showed that learning and memory function had been significantly impaired in rats of DM with CSVD since the 7th day of modeling. …”
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Modeling and Analysis of Noise Reduction Method in SPAD-Based LiDAR System by Kai Ma, Tao Yin, Na Tian, Zhe Wang, Tian Zhao, Jian Liu, Nanjian Wu, Liyuan Liu

“…A behavioral model is established, enabling the simulation of the comprehensive functionality of a SPAD-based LiDAR system in either first-hit mode or multi-event mode, including the histogramming, coincident detection, time- gating functions. …”
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Exploration and Exploitation Mechanism in Pairwise Test Case Generation: A Systematic Literature Review by Muhammad Sabo Yahaya, Ahmad Sobri B. Hashim, Abdullateef Oluwagbemiga Balogun, Aminu Aminu Muazu, Fatima Sabo Usman, Dahiru Adamu Aliyu, Abdullahi Uwaisu Muhammad

“…These methods consistently outperform traditional techniques by reducing test suite sizes and enhancing fault detection capabilities. …”
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