Comprehensive GWAS and Transcriptome Analysis Discovered Candidate Gene Associated with Starch Pasting Properties of Temperate japonica rice (Oryza sativa L.) by Yoon Kyung Lee, Su Jang, Jihwan Im, Hee-Jong Koh

“…Haplotype analysis revealed significant variations in viscosity traits associated to OsGLUTN alleles, and functional validation using enhancer active tagging line showed significantly reduced starch viscosity, confirming its role in EQ regulation. …”
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Water-soluble garlic polysaccharide (WSGP) improves ulcerative colitis by modulating the intestinal barrier and intestinal flora metabolites by Xin Shao, JiaLong Li, Qi Shao, Rong Qu, Xin Ouyang, Yong Wang, ChunBo Chen

“…This study demonstrates that WSGP supplementation attenuates UC mice by suppressing the NF-κB/STAT3 signaling pathway, enhancing mucosal barrier function, reducing pro-inflammatory cytokines, and modulating gut microbial metabolites.…”
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A universal ground test equipment design for the Chang’e series spacecraft by Wenjie Zhao, Wenjie Zhao, Jianing Rao, Jianing Rao, Cheng Hao, Wenyuan Jia, Zhenxing Dong, Zhenxing Dong, Xiaoyong Ma, Miao Ma, Wenhui Yang, Wenhui Yang, Yan Zhu, Yan Zhu, Junshe An, Junshe An

“…To address these issues, this paper proposes a universal ground testing device that integrates remote control and telemetry communication, scientific data transmission, as well as AD (Analog-to-Digital) and OC (Open Collector) signal detection, and DA (Digital-to-Analog) and Open Collector signal output functions through a modular architecture. …”
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Potential innovations from the application of beneficial soil microbes to promote sustainable crop production by Chinenyenwa Fortune CHUKWUNEME, Ayansina Segun AYANGBENRO, Vittori VENTURI, Bernard R. GLICK, Olubukola Oluranti BABALOLA

“…However, microorganisms that are found in the rhizosphere can aid in the mobilization of essential soil nutrients, facilitate plant growth, and reduce abiotic and biotic stresses of plants. Soil microbes accomplish these beneficial functions via several mechanisms. …”
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SEX DIFFERENCES OF VLF100 AND VLF50 SPECTRUM OF HEART RATE VARIABILITY IN HEALTHY INDIVIDUALS OF YOUNG AGE AND OLDER SUBJECTS WITH VASCULAR PATHOLOGY IN TERMS OF SEVEN-TEST, HYPERV... by Арнольд Наумович Флейшман, Татьяна Валентиновна Кораблина, Игорь Германович Халиулин, Станислав Альфредович Петровский, Артем Андреевич Неретин

“…Unlike women functional loads increased the power of 10 sec. rhythms in men with vagal dominance. …”
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Alfacalcidol in clinical practice: focus on the efficacy and safety of the Russian generic drug by N. V. Toroptsova, M. V. Kozyreva, O. V. Dobrovolskaya

“…In addition to sufficient physical activity, medications are needed that have a positive effect on the strength and functional performance of the skeletal muscles. Vitamin D supplements play a key role in this therapeutic approach.Objective: to investigate the tolerability, safety and efficacy of the generic drug Alfacalcidol Canon on the functional status of patients with reduced bone mineral density in clinical practice.Material and methods. …”
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A synbiotic combination of mixed probiotics and oligofructose restores intestinal microbiota disturbance in DSS-induced colitis in mice by Weiwei Ma, Lian Lian, Lidong Guo, Yanan Wu, Lili Huang

“…The results showed that the combination of mixed probiotics and oligofructose could significantly alleviate the symptoms of colitis in mice, improve the weight loss symptoms of DSS mice, reduce the diarrhea index, restore the colon length, reduce tissue pathological damage, and improve the integrity of the intestinal barrier. …”
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The in vitro mechanism of Vaspinregulates the proliferation and steroidogenesis of rat lutein cells by Xiao-wen Fu, Ling Liu, Xiao-yu Zhu, Jian-jun Wang

“…Objective Stable luteal cell function is an important prerequisite for reproductive ability and embryonic development. …”
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The Impact of Physical Activity on Breast Cancer Prevention by Krystian Zukierski, Weronika Jarych, Katarzyna Michalak, Michał Mazur, Katarzyna Żak, Aleksandra Pliszka, Hubert Jucha, Katarzyna Madyniak, Agnieszka Kluz

“…Preventive strategies, especially those emphasizing the promotion of physical activity, play a crucial role in breast cancer prevention by positively influencing hormonal regulation, reducing systemic inflammation, and enhancing metabolic functions. …”
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Pregnancy-acquired memory CD4+ regulatory T cells improve pregnancy outcome in mice by Kristin Thiele, Christopher Urbschat, Julia. Isabel. Amambay Riquelme, Lisa. Sophie Ahrendt, Ronja Wöhrle, Steven Schepanski, Judith Joana Eckert, Etienne Becht, Minyue Qi, Malik Alawi, Martin Becker, Nicola Gagliani, Hans-Willi Mittrücker, Anke Diemert, Petra Clara Arck

“…Here we identify higher frequencies of fetal-antigen-specific CD4+ regulatory T (Treg) cells both postpartum and in subsequent pregnancies in mice which are partly originating from trans-differentiated Th17 cells. Our functional experiments demonstrate that these CD4+ Treg cells have memory functions (CD4+ mTreg) and account for an improved fetal development and pregnancy outcome, also during adverse conditions, such as gestational sound stress. …”
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Multiparametric MRI for the improved diagnostic accuracy of Alzheimer's disease and mild cognitive impairment: Research protocol of a case-control study design. by Albert Dayor Piersson, Buhari Ibrahim, Subapriya Suppiah, Mazlyfarina Mohamad, Hasyma Abu Hassan, Nur Farhayu Omar, Mohd Izuan Ibrahim, Ahmad Nazlim Yusoff, Normala Ibrahim, M Iqbal Saripan, Rizah Mazzuin Razali

“…Magnetic resonance imaging (MRI) using structural MRI (sMRI), functional MRI (fMRI), diffusion tensor imaging (DTI), and magnetic resonance spectroscopy (1H-MRS) performed alone is inadequate. …”
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PREGNANCY AND DENTAL HEALTH: NAVIGATING THE COMPLEXITIES OF ORAL CARE, RISKS AND PREVENTIVE APPROACHES FOR EXPECTANT MOTHERS by Ciprian Gavrila Ilea, Irina Liviana Stoian, Alexandra Pangal, Bogdan Doroftei, Adeline Samar Nassouh, Laurian Lucian Francu, Corina Ciupilan, Monica Mihaela Scutariu

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SEARCH FOR CLINICAL PREDICTORS OF PULMONARY HYPERTENSION IN PATIENTS WITH SYSTEMIC SCLEROSIS by N. A. Klyaus, M. A. Simakova, A. L. Maslyansky, O. M. Moiseeva

“…PH was detected in 10 of the 57 patients enrolled in the trial. …”
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Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis by Alexandra T. Matola, Dorottya Csuka, Ágnes Szilágyi, Michael Rudnicki, Zoltán Prohászka, Mihály Józsi, Barbara Uzonyi

“…Antibody–antigen complexes were detected in the patient’s serum using Western blot. …”
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Blockade of PVN neuromedin B receptor alleviates inflammation via the RAS/ROS/NF-κB pathway in spontaneously hypertensive rats by Kai-Li Liu, Tian-Ze Sun, Yu Yang, Qian-Xi Gao, Li-Mei Tu, Jia-Yue Yu, Qiao-Zhen Tian, Li-Yan Fu, Shu-Huan Tang, Hong-Li Gao, Jie Qi, Yu-Ming Kang, Xiao-Jing Yu

“…However, studies regarding the NMB function in paraventricular nucleus (PVN) are lacking. …”
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Unraveling the molecular mechanisms of Fufangduzhong formula in alleviating high-fat diet-induced non-alcoholic fatty liver disease in mice by Yu Mou, Yu Mou, Yu Mou, Yao Tang, Yao Tang, Yao Tang, Xiuyan Zheng, Xiang Liu, Xiang Liu, Xiang Liu, Xuemei Wu, Xuemei Wu, Xuemei Wu, Hongji Wang, Hongji Wang, Hongji Wang, Jie Zeng, Jie Zeng, Jie Zeng, Qing Rao, Qing Rao, Qing Rao, Yaacov Ben-David, Yaacov Ben-David, Yaacov Ben-David, Yaacov Ben-David, Yanmei Li, Yanmei Li, Yanmei Li, Lei Huang, Lei Huang, Lei Huang

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Age-dependent cortical overconnectivity in Shank3 mice is reversed by anesthesia by Elena Montagni, Manuel Ambrosone, Alessandra Martello, Lorenzo Curti, Federica Polverini, Laura Baroncelli, Guido Mannaioni, Francesco Saverio Pavone, Alessio Masi, Anna Letizia Allegra Mascaro

“…Notably, the severity of FC imbalance is highly dependent on the brain state: global network alterations are more pronounced in the awake state and are strongly reduced under anesthesia. These results underscore the crucial role of anesthesia in detecting autism-related FC alterations and identify a significant network of early cortical dysfunction associated with autism. …”
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INDICATORS OF CYTOKINE ACTIVITY AND BETA-ENDORPHIN PRODUCTION LEVEL IN ARTERIAL HYPERTENSION ASSOCIATED WITH ASTHENIC/NEUROTIC DISORDERS IN YOUNG MEN EMPLOYED IN STRESSFUL PROFESSI... by A. V. Gertsev, V. N. Ischuk, Yu. N. Zakrevsky

“…Neuropeptide-cytokine profile of the immune system was evaluated by levels of proinflammatory cytokines (TNFα, IL-1β, IL-6), antiinflammatory cytokines (IL-4, IL-10), and β-endorphin.In the course of clinical and laboratory examination, we have found that, in the patients with hypertension and astheno-neurotic disorders, activation of proinflammatory cytokines (TNFα, IL-1β, IL-6), suppression of anti-inflammatory cytokines (IL-4, IL-10), and reduced β-endorphin in the blood are registered. Moreover, the disturbances detected showed the mutual interactions between autonomic nervous and immune systems in these patients.…”
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The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence. by Patricia P Peterson, Jin-Tae Choi, Ci Fu, Leah E Cowen, Sheng Sun, Yong-Sun Bahn, Joseph Heitman

“…Here, STRIPAK components Pph22, Far8, and Mob3 were functionally characterized. Whole-genome sequencing revealed that mutations in STRIPAK complex subunits lead to increased segmental and chromosomal aneuploidy, suggesting STRIPAK functions in maintaining genome stability. …”
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Metabolic characterization of selected probiotic consortia during gluten and wheat bread simulated digestion by Mirco Vacca, Giuseppe Celano, Olga Nikoloudaki, Bodo Speckmann, Francesco Maria Calabrese, Marco Gobbetti, Maria de Angelis

“…As functional contribution, digested extracts with MCs also proved to reduce the inflammatory cytokine concentrations in cell lines exposed to lipopolysaccharide trigger. …”
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