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2721
Role of T cell exhaustion and tissue-resident memory T cells in the expression and prognosis of colorectal cancer
Published 2025-08-01“…Early stage pf-Trm cells actively participate in immune surveillance and antigen presentation, whereas advanced stage pf-Trm cells exhibit reduced functions. Flow cytometry analysis of clinical cohorts was used to measure the proportions of Tex and pf-Trm. …”
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2722
A dataset of hidden small non-coding RNA in the testis of heat-stressed models revealed by Pandora-seq
Published 2024-07-01“…Male infertility, stemming from spermatogenic dysfunction and reduced sperm quality, stands as a primary factor contributing to infertility. …”
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2723
Novel coronavirus infection SARS-CoV-2 in elderly and senile patients: prevention, diagnosis and treatment. Expert Position Paper of the Russian Association of Gerontology and Geri...
Published 2020-07-01“…Management of elderly and senile patients with COVID19 should include measures for delirium prevention, the detection and improvement of nutrition. The risk of malnutrition with sarcopenia increases with hospitalization of a patient, especially when using artificial ventilation, is associated with an unfavorable prognosis during hospitalization, accelerates the progression of senile asthenia and reduces the quality of life. …”
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2724
Plant-mediated synthesis of metal oxide nanocomposites: emerging prospects in electrochemical corrosion inhibition and biosensing
Published 2025-12-01“…The article discusses synthesis methods, characterization techniques, electrochemical performance metrics, and application specific functionalities, identifying key challenges including reproducibility, real-sample performance, and scale up feasibility. …”
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2725
The immunopeptidome of colon cancer cells treated with topoisomerase inhibiting drug reveals differential as well as common endogenous protein sampling and display of MHC I-associa...
Published 2025-12-01“…Gene Ontology analysis of MHC I-displayed proteins revealed a treatment-induced increase in extracellular vesicle- and nuclear-derived proteins, alongside reduced cytosolic protein sampling. Overall, we present evidence for treatment-inducible differential display of peptides, some of which may affect interactions and functions of immune cells. …”
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2726
Molecular classification of head and neck squamous cell carcinoma based on hypoxia-related genes and clinical significance of STC2
Published 2025-05-01“…Objective To construct a molecular classification system for head and neck squamous cell carcinoma (HNSCC) utilizing hypoxia-related gene (HAG) expression profiles, and to comprehensively examine the clinicopathological significance and biological functions of the hypoxia gene stanniocalcin 2 (STC2) in HNSCC. …”
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2727
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2728
Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway
Published 2021-07-01“…Eight-week administration with GIPS at doses of 30 or 90 mg/kg strongly inhibited tumor growth including the reduction on numbers and the suppression of the size without influencing the animals’ body weight and organ functions. According to the proteomics performing by antibody array, among 308 detected cytokines, GIPS significantly regulated 89 of them. …”
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2729
Immunogenicity of Pneumococcal Polysaccharide Vaccine in patients with rheumatoid arthritis
Published 2024-09-01“…IgG AT generated in response to PPV23 injection shown functional activity even in RA patients whose antibodies were either lowered in patients receiving MTX or were not detectable at protective values following bDMARD therapy. …”
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2730
Low-viscosity oligoether esters (OEEs) as high-efficiency lubricating oils: Insight on their structure–lubricity relationship
Published 2023-12-01“…Abstract Development of energy-efficient lubricants is a way to reduce energy consumption for transportation, with the tendency to design molecules that are beneficial in reducing the viscosity of synthetic oils. …”
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2731
The classical-to-quantum crossover in the strain-induced ferroelectric transition in SrTiO3 membranes
Published 2025-05-01“…With reduced thickness, the SrTiO3 membranes remain elastic with >1% tensile strain cycles. …”
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2732
The clinical application of mitoxantrone hydrochloride tracing in endoscopic radical resection of thyroid carcinoma
Published 2025-07-01“…Abstract To evaluate the effectiveness of tracer mitoxantrone hydrochloride injection (MHI) in mapping central lymph nodes and its role in preserving parathyroid function during endoscopic radical resection of thyroid carcinoma. …”
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2733
Antioxidant Capacity and Phenolic Profile of Defatted Seed Powder Derived from Organically Grown Vine Crops
Published 2024-11-01“…The phenolic profile was determined using High-performance liquid chromatography with diode array detection and mass spectrometry operating in electrospray ionization positive mode, while the total phenolic content was determined using an adapted Folin-Ciocalteu technique, The samples' antioxidant properties were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging ability assessments, as well as Cupric ion reducing antioxidant capacity and Ferric reducing antioxidant power assays. …”
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2734
METHOD THERAPEUTIC INTERVENTION ON PHYSICAL STABILITY AMONG ELDERLY INDIVIDUALS IN KAKAMEGA COUNTY
Published 2024-07-01“…Despite physical activity being known to reduce fall risks, existing studies face challenges like high drop-out rates and limited exercise types. …”
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2735
SHOULD DISEASE-MODIFYING THERAPY BE STOPPED IN PATIENTS WITH RHEUMATOID ARTHRITIS BEFORE ENDOPROSTHETIC JOINT REPLACEMENT?
Published 2011-06-01“…QL was determined using the EQ-5D questionnaire and functional capacity was estimated by the HAQ index. …”
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2736
A Neural Device Inspired by Neuronal Oscillatory Activity with Intrinsic Perception and Decision‐Making
Published 2025-03-01“…This is accomplished using a single interface, which reduces data transmission, simplifies functionality, and eliminates the need for an external power supply. …”
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2737
Immunological parameters in patients with chronic opisthorchiasis coupled to mutant genes associated with predisposition to arterial hypertension development
Published 2025-04-01“…To identify the features of immune system functioning in patients with chronic opisthorchiasis coupled to mutant gene loci associated with arterial hypertension predisposition, comprehensive studies on innate and adaptive immunity were conducted. …”
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2738
Quantitative Proteomics Revealed the Molecular Regulatory Network of Lysine and the Effects of Lysine Supplementation on Sunit Skeletal Muscle Satellite Cells
Published 2025-05-01“…TMT proteomics identified differentially expressed proteins, which underwent functional and interaction analyses, with RT-qPCR validating the corresponding gene expression. …”
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2739
Research on the Thermal Decomposition Characteristics of PE Outer Sheath of High-Voltage Cables Under Different Humidity Levels
Published 2025-07-01“…Gas sensors can provide early warning of fires by detecting pyrolysis gas components in the sheaths of high-voltage cables. …”
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2740
Identification of non-volatile components and anti-fatigue effect of a compound Lujiu
Published 2024-08-01“…Compared with the model group, the body weight reduction of mice in the low, medium and high dose groups was significantly reduced (P<0.01), the weight-bearing swimming time of mice in the medium and high dose groups was significantly prolonged (P<0.01), the content of blood urea nitrogen (BUN) of mice in low and medium dose groups was significantly increased (P<0.01, P<0.05), the activity of lactate dehydrogenase (LDH) and the content of liver glycogen (LG) of mice in the low, medium and high dose groups were significantly increased (P<0.01, P<0.05), indicating that the compound Lujiu was rich in non-volatile substances, which could enhance the body's adaptability to load and had a significant anti-fatigue effect, providing a certain foundation for the development of functional foods.…”
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