Automated Detection of Reduced Ejection Fraction Using an ECG-Enabled Digital Stethoscope by Ling Guo, PhD, Gregg S. Pressman, MD, Spencer N. Kieu, BS, Scott B. Marrus, MD, PhD, George Mathew, PhD, John Prince, PhD, Emileigh Lastowski, MS, Rosalie V. McDonough, MD, MSc, Caroline Currie, BA, John N. Maidens, PhD, Hussein Al-Sudani, MD, Evan Friend, BA, Deepak Padmanabhan, MD, Preetham Kumar, MD, Edward Kersh, MD, Subramaniam Venkatraman, PhD, Salima Qamruddin, MD

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Circulating Cell-Free Nuclear DNA Predicted an Improvement of Systolic Left Ventricular Function in Individuals with Chronic Heart Failure with Reduced Ejection Fraction by Tetiana Berezina, Oleksandr O. Berezin, Michael Lichtenauer, Alexander E. Berezin

“…The identification of predictors for HFimpEF may play a crucial role in the individual management of HF with reduced ejection fraction (HFrEF). Cell-free nuclear (cf-nDNA) DNA is released from damaged cells and contributes to impaired cardiac structure and function and inflammation. …”
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The association of serum hsa-miR-21-5p expression with the severity and prognosis of heart failure with reduced ejection fraction by Lingmiao Wang, Ailin Guo, Shuang Liang, Lingling Yu, Bai Shen, Zhihang Huang

“…Abstract Background Heart failure poses a huge burden on the global population, and approximately 50% cases have reduced ejection fraction, namely, heart failure with reduced ejection fraction (HFrEF). …”
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Case of Acute Graft Failure during Suspected Humoral Rejection with Preserved Ejection Fraction, but Severely Reduced Longitudinal Deformation Detected by 2D-Speckle Tracking by Tor Skibsted Clemmensen, Hans Eiskjær, Pernille B. Kofoed-Nielsen, Søren Høyer, Steen Hvitfeldt Poulsen

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Detecting and reducing heterogeneity of error in acoustic classification by Oliver C. Metcalf, Jos Barlow, Yves Bas, Erika Berenguer, Christian Devenish, Filipe França, Stuart Marsden, Charlotte Smith, Alexander C. Lees

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Time-Adaptive Machine Learning Models for Predicting the Severity of Heart Failure with Reduced Ejection Fraction by Trevor Winger, Cagri Ozdemir, Shanti L. Narasimhan, Jaideep Srivastava

“…<b>Background:</b> Heart failure with reduced ejection fraction is a complex condition that necessitates adaptive, patient-specific management strategies. …”
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Possible risk factors for atrial fibrillation in patients with heart failure with mildly reduced ejection fraction by L. G. Azarapetyan, G. G. Hayrapetyan, S. V. Grigoryan

“…To study possible risk factors (RFs) for the development of paroxysmal and persistent atrial fibrillation (AF) in patients with heart failure with mildly reduced ejection fraction (HFmrHF).Material and methods. …”
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Pentoxyphylline: possibilities to reduce manifestations of chronic heart failure with preserved left ventricular ejection fraction in elderly by V. B. Shatylo, L. A. Bodretska, I. S. Shapovalenko, H. P. Voinarovska, Zh. S. Butynets

“…The aim: to study the effect of add-on pentoxifylline therapy on the structural and functional indicators of the heart state, endothelial function, quality of life and physical abilities in patients with chronic heart failure with preserved left ventricular ejection fraction. …”
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Incidence of Rapid Rate Non‐Sustained and Sustained Ventricular Tachycardia in Implantable Cardioverter‐Defibrillator Recipients and Its Correlation With Heart Failure Guideline‐Di... by Muhammad Taha Khan, Ghazala Irfan, Sarim Ansari, Zubair Mumtaz, Faisal Qadir, Azam Shafquat

“…ABSTRACT Background Ventricular arrhythmias are prevalent among heart failure with reduced ejection fraction (HFrEF) patients. Rapid rate non‐sustained ventricular tachycardia (RR‐NSVT) and sustained ventricular tachycardia (VT) can be detected on implantable cardioverter‐defibrillator (ICD) interrogation due to discrimination algorithms that differentiate supra‐ventricular from ventricular tachycardia. …”
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Frequency of hemodynamic response to orthostatic stress in heart failure with reduced ejection fraction, associations with clinical blood pressure by D. N. Fedorova, A. E. Soloveva, M. Fudim, V. L. Galenko, A. V. Kozlenok, A. V. Berezina, S. V. Villevalde

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Reduced graphene oxide-based absorbance biosensors for detecting Escherichia coli DNA by Chau Nguyen Minh Hoang, Son Hai Nguyen, Mai Thi Tran

“…The functionalized reduced graphene oxide was successfully synthesized using a modified Hummers’ method, followed by a hydrothermal reduction step. …”
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Electrocardiographic signs of impaired depolarization (fragmented QRS, early ventricular repolarization, etc.) as markers of left ventricular systolic dysfunction by M. S. Gordeeva, I. A. Serdiukova, A. S. Krasichkov, E. V. Parmon

“…To study the relationship between a decrease in left ventricular (LV) ejection fraction (EF) and conventional electrocardiographic (ECG) signs associated with myocardial structure changes (pathological Q wave, ventricular arrhythmias), and relatively novel and less studied (fragmented QRS (fQRS), early ventricular repolarization (EVR)) and to evaluate their significance for identifying patients with mildly-reduced EF (mrEF).Material and methods. …”
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Heart failure with preserved ejection fraction: the role of diastolic stress test in diagnostic algorithms by E. N. Pavlyukova, D. A. Kuzhel

“…Despite the preserved left ventricular (LV) and a moderate increase in natriuretic peptide, patients  with HFpEF have the same out-of-hospital mortality as those with HF with reduced ejection fraction (HFrEF). Diagnosis of HFpEF is difficult due to nonspecific symptoms, expensive blood tests, and questionable rest echocardiographic data on diastolic function. …”
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Persistent Fibrosis in Heart Failure With a Reduced Ejection Fraction Linked to Phenotypic Differences in Human Cardiac Fibroblast Populations by Rachel M. Biggs, Yuhua Zhang, Daniel N. Silverman, Catalin F. Baicu, An O. Van Laer, Lauren Wakefield, Devki Bhatt, Stephanie Masline, Lily S. Neff, Arman Kilic, Lucas J. Witer, Brian A. Houston, Samuel J. Coeyman, William J. Richardson, Michael R. Zile, Amy D. Bradshaw

“…Background Myocardial fibrosis is prevalent in cardiomyopathies that result in heart failure with reduced ejection fraction. Heart failure with reduced ejection fraction treated with a left ventricular assist device (LVAD) yields hemodynamic unloading and may provide partial cardiomyocyte recovery, but contemporary studies reveal no consistent reductions in fibrosis. …”
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Reduced graphene oxide-based electrochemical aptasensor for the multiplexed detection of imidacloprid, thiamethoxam, and clothianidin in food samples by Asma Zaid Almenhali, Pandiyaraj Kanagavalli, Marwa Abd-Ellah, Salma Khazaal, Nada El Darra, Shimaa Eissa

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SGLT2 inhibitor with and without ALDosterone AntagonIst for heart failure with preserved ejection fraction: Design paper by João Pedro Ferreira, Francisco Vasques‐Nóvoa, Francisca Saraiva, Ana C. Oliveira, Jorge Almeida, Ana Beatriz Batista, Arsénio Barbosa, Ana Filipa Ferreira, Cátia Costa, Diogo Santos‐Ferreira, Fernando Friões, Cândida Goncalves, João Tiago Guimarães, Marta Leite, Pedro Marques, Joana Mascarenhas, Maria Inês Matos, Catarina Pereira, Pedro Rodrigues, Abhinav Sharma, Gualter Silva, Inês Pereira‐Sousa, Carla Sousa, Faiez Zannad, Joana Pimenta, Ricardo Fontes‐Carvalho, Adelino Leite‐Moreira

“…Abstract Background Sodium glucose co‐transporter 2 inhibitors (SGLT2i) and mineralocorticoid receptor antagonists (MRA) reduce heart failure (HF) events in patients with heart failure and mildly reduced or preserved ejection fraction (HFmr/pEF). …”
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Wide-Based Illumination and Detection in Functional Near-Infrared Spectroscopy for Enhanced Seizure Detection in Grey Matter by Netaniel Rein, Revital Shechter, Evgeny Tsizin, Mordekhay Medvedovsky, Michal Balberg

“…Functional near-infrared spectroscopy (fNIRS) is a non-invasive method for monitoring brain activity by detecting hemodynamic changes. …”
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Correlation between serum matrix metalloproteinase and myocardial fibrosis in heart failure patients with reduced ejection fraction: A retrospective analysis by Ömer Çelik, Ahmet Anıl Şahin, Serdar Sarıkaya, Begüm Uygur

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SARE: an optimized method for detection functional regulatory elements in genome by Mohammadjavad Hosseinpoor

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Incremental diagnostic value of coronary computed tomography angiography derived fractional flow reserve to detect ischemia by Isabelle Ried, Insa Krinke, Rafael Adolf, Markus Krönke, Seyed Mahdi Moosavi, Eva Hendrich, Albrecht Will, Keno Bressem, Martin Hadamitzky

“…Combined CCTA and CT-FFR have improved diagnostic accuracy compared to CCTA alone in detecting ischemia on the coronary vessel level and thus could reduce the use of invasive coronary angiography in the future.…”
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