A review to determine regulatorily and reimbursement successes of studies conducted using data from Canadian patient support programs based on the real-world evidence guidelines published by Canadian drug agency and health Canada by Catherine Y. Lau

“…Data collected from these programs generate unique Canadian data serving as a valuable source of real-world data (RWD), generally adopted in EU and US as a source of evidence generation. …”
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Real-world effectiveness and safety of first-line chemoimmunotherapy combinations in metastatic non-small cell lung cancer with programmed death ligand-1 < 50%: results from an Italian observational study by Alessandro Inno, Antonello Veccia, Ettore D’Argento, Floriana Morgillo, Elio Gregory Pizzutilo, Fabiana Vitiello, Alberto Pavan, Fiorella Lombardo, Marco Russano, Vincenzo Sforza, Francesca Colamartini, Carlo Genova, Rita Chiari, Antonella Cristofano, Alessandro Delconte, Emanuela Vattemi, Alessandra Dessi, Daniele Galanti, Simona Busato, Giovanni Palazzolo, Clementina Savastano, Antonio Bianco, Francesco Verderame, Cristina Mazzi, Fabiana Marchetti, Stefania Kinspergher, Denis Occhipinti, Carminia Maria Della Corte, Daniele Piscazzi, Marina Gilli, Emilio Bria, Orazio Caffo, Stefania Gori

“…Abstract Introduction This multi-center, observational cohort study aimed to evaluate the real-world effectiveness and safety of two first-line chemoimmunotherapy combinations—pembrolizumab plus chemotherapy and nivolumab/ipilimumab plus chemotherapy—in patients with metastatic non-small cell lung cancer (NSCLC) and programmed death ligand-1 (PD-L1) expression < 50%. …”
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Experience from Turkish centers participating in the Early Access Program (EAP): Preliminary real-world safety data of nivolumab (nivo) combined with ipilimumab (ipi) in pre-treated advanced melanoma patients by Nuri Karadurmus, Mehmet Ali Nahit Sendur, Burcak Karaca, Omer Fatih Olmez, Ilhan Hacibekiroglu, Hasan Senol Coskun, Serkan Degirmencioglu, Yasemin Kemal, Saadettin Kilickap, Ahmet Taner Sumbul, Burc Aydin, Hande Turna, Muhammet Ali Kaplan, Nalan Babacan, Umut Demirci, Alper Ata, Dilek Erdem, Ahmet Ozet, Huseyin Abali

“…Objective: We aimed to evaluate the safety of nivolumab + ipilimumab (nivo + ipi) in advanced melanoma patients who had relapsed after ≥1 line of systemic treatment in a real-world setting. Methods: Adult patients with advanced melanoma who had progressed after ≥1 line of systemic treatment were eligible for nivo 1 mg/kg + ipi 3 mg/kg Q3W × 4, followed by nivo 3 mg/kg Q2W until progression, or unacceptable toxicity for up to 24 months in the Early Access Program (EAP) in Turkey. …”
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Real-Time Controller Based on FPGA and DSP for Solar Ground Layer Adaptive Optics Prototype System at 1-m NVST by Lin Kong, Lei Zhu, Lanqiang Zhang, Hua Bao, Changhui Rao

Subjects: “…Real-time controller…”
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Two Weighted Fuzzy Goal Programming Methods to Solve Multiobjective Goal Programming Problem by Mousumi Gupta, Debasish Bhattacharjee

“…Mohamed proposed that every fuzzy linear program has an equivalent weighted linear goal program where the weights are restricted as the reciprocals of the admissible violation constants. …”
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Fuzzy goal programming approach for solving linear fractional programming problems with fuzzy conditions by Rajeev Prasad, Indrani Maiti, Sapan Das, Surapati Pramanik, Tarni Mandal

“…Due to high information uncertainty and complicated factors influencing the industrial sector, traditional data-driven prediction approaches can hardly reflect real changes in practical situations. Fuzzy programming is a powerful prediction reasoning and risk assessment model for uncertain environments. …”
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A PRACTICE OF OPEN DATA ADOPTION TO «PROGRAMMING» COURSE OF «SOFTWARE ENGINEERING» BACHELOR PROGRAM by Olga V. Maksimenkova, Vadim V. Podbelskiy

“…The technique of the use of open data sets when developing training and control tasks on programming for students of a bachelor degree of information and technological educational program specialization is offered; standard tasks templates are presented.The application of open data in the educational purposes is a rather new direction in education that considerably enables to improve the quality of training of an expert in the field of computer sciences: to bring closer educational tasks to real; to increase variability of control tasks; to increase motivation of students. …”
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Design of Auxiliary Inverter Debug Diagnosis by YAN Zhiyong, ZENG Minggao, DUAN Luping, YUAN Fang, PENG Xuebiao, ZHONG Yuan

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MODELING OF PROCESSES IN APPLICATION PROGRAM by G. A. Mankaeva, L. N. Dzhimbeeva, B. B. Mikhaliaev, S. B. Derteev, A. B. Matsakova, M. A. Trofimenko

“…Since people learned to create models and conduct calculations on Basiq, Fortran, there have been many attempts to recreate physical processes close to real ones, mathematical programs have replaced these programs - Maple, MATLAB, Mathematica, and also special software - an interactive environment for modeling and imitation of scientific and technical processes COMSOL Multiphysics.…”
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ARP: asexual reproduction programming by Alireza Khanteymoori, Fatemeh Alamdar, Farzaneh Ghorbani

“…GP was developed to evolve programming in computers and is a population-based algorithm. …”
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Real-Time Cyber-Physical Digital Twin for Low Earth Orbit Satellite Constellation Network Enhanced Wide-Area Power Grid by Tianshi Cheng, Tong Duan, Venkata Dinavahi

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Integration of anti-PD-1 antibody into chemotherapeutic regimens improved the outcome of aggressive NK cell leukemia: a single-center retrospective real-world analysis by Kai Shen, Yi Liao, Yang Dai, Jie Ji, Pu Kuang, Zhigang Liu, Liping Xie, Ting Niu, Nenggang Jiang, Hongbing Ma

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Power BI as an auxiliary tool for biostatistics by N. Yu. Dmitrieva

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MODELING OF OPTIMAL PROGRAM OF PRODUCTION AND SALES by V. M. Machulin, V. E. Sidorchuk

“…Optimization of production program and binding of expenses to the real situation is one of the ways to change the strategy of the enterprise development.…”
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A Program for Master of Information Technology by Kabale University

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Accuracy of colposcopy in the Swedish screening program by Emilia Alfonzo, Chenyang Zhang, Forogh Daneshpip, Björn Strander

“…Abstract Introduction Sensitivity and specificity of colposcopy vary greatly between studies and efficacy in clinical studies seldom corresponds with effectiveness in a real‐life setting. It is unclear whether colposcopists’ experience affects assessment; studies show divergent results. …”
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Benefits of the Person-Oriented Perspective for Program Evaluation: Analyzing the Differential Treatment Effects of the Vienna E-Lecturing Program by Dominik Lapka, Petra Wagner, Barbara Schober, Petra Gradinger, Christiane Spiel

“…Setting: Both approaches will be applied in the evaluation of a showcase program conducted in real life setting. The results of the two perspectives will be compared. …”
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Program Report—Transplant Manitoba Adult Kidney Program Cutting Costs, Not Corners: Value of Quality Improvement Initiatives by Christie Rampersad, Aaron Trachtenberg, James Shaw, Nancy Dodd, Krista Maxwell, Martin Karpinski, Chris Wiebe, Peter Nickerson, Julie Ho

“…Sources of information: Transplant Manitoba Adult Kidney Program database and quality metrics, Manitoba Health Physician’s Manual (April 1, 2024), PubMed. …”
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Small Group Learning in Real Property Law by Adiva Sifris, Elspeth McNeil

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Real time Data Acquisition of Solar Panel by Youssef Rehouma, Mohamed Abd El basset Mahboub, Aicha Degla, Djafer Ghorma, Ahmed Abd Alouareth Nadjemi

“…We created a real-time acquisition system to track the voltage, current and temperature changes of the solar panel as we installed it in a charging regulator with a battery. …”
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