TREATMENT FOR ACUTE/SUBACUTE MUSCULOSKELETAL PAIN, BY USING AN ALGORITHM FOR STEPWISE CHOICE OF ANALGESIC DRUGS AND FOR MONITORING THEIR EFFICACY: PRELIMINARY DATA OF THE ANALGESIC... by N. V. Gontarenko, A. V. Tsurgan, A. E. Karateev

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A Post-Authorisation Safety Study of a Respiratory Syncytial Virus Vaccine in Pregnant Women and Their Offspring in a Real-World Setting: Generic Protocol for a Target Trial Emulat... by Odette de Bruin, Linda Nab, Jungyeon Choi, Oisin Ryan, Hae-Won Uh, Fariba Ahmadizar, Shahar Shmuel, Heather Rubino, Kitty Bloemenkamp, Cynthia de Luise, Miriam Sturkenboom

“…<b>Background:</b> Assessing the real-world safety of preventive products against respiratory syncytial virus (RSV) in pregnant women holds significant public health implications, especially as vaccination programs become more widespread. …”
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First-line pembrolizumab in patients with advanced non-small cell lung cancer and high PD-L1 expression: real-world data from a Spanish multicenter study by Aida Piedra, Aida Piedra, Sergio Martínez-Recio, Ainhoa Hernández, Teresa Morán, Edurne Arriola, Jordi Recuero-Borau, Manuel Cobo, Patricia Cordeiro, Joaquín Mosquera, Manuel Fernández, Rosario García-Campelo, Antonio Calles, Rosa Álvarez, María Zapata-García, Dolores Isla, Ana Callejo, Patricia Iranzo, Jorgina Serra-López, Andrés Barba, Ivana Sullivan, Enriqueta Felip, Margarita Majem

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A toolbox for the identification of foot-floor contact sequences to analyze atypical gait cycles in a real-life scenario: application on patients after proximal femur fracture and... by Marco Ghislieri, Nicolas Leo, Marco Caruso, Clemens Becker, Andrea Cereatti, Valentina Agostini

“…Abstract Background The detection of gait subphases is pivotal for a comprehensive assessment of gait quality, playing a key role in different applications such as rehabilitation programs, movement disorder diagnostics, and fall prevention strategies. …”
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A real-world study on the efficacy and safety of low-dose PD-1 monoclonal antibody alone or in combination as the first-line treatment for advanced non-small cell lung cancer by Tao Han, Xin Li, Lu Xu, Jingqi Sun, Junli Hao, Sha Shi, Heming Li, Mingfang Zhao

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The comparison of efficacy and safety between cadonilimab (PD-1/CTLA-4) and anti-PD-1 inhibitors in patients with recurrent or metastatic cervical cancer: a retrospective real-worl... by Baoyue Pan, He Huang, Ting Wan, Qidan Huang, Shanyang He, Shijie Xu, Siyu Chen, Jiaxin Yin, Jundong Li, Min Zheng

“…However, the efficacy of cadonilimab in patients with prior failure of anti- programmed death receptor-1 (PD-1) inhibitors, as well as a direct comparison of its efficacy and safety with anti-PD-1 inhibitors, has not been reported in real-world settings.MethodsWe conducted a retrospective study at our hospital, including two R/M CC patient cohorts. …”
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Protocol of the TransformUs Secondary schools program: a type II hybrid implementation-effectiveness trial to increase adolescents’ physical activity and reduce sedentary time in s... by Harriet Koorts, Anna Timperio, Jo Salmon, David Revalds Lubans, Gavin Abbott, Nicola D Ridgers, Natalie Lander, Ana María Contardo Ayala, Emiliano Mazzoli

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Herbal medicine evaluation for reimbursement-based facial palsy (HERB-FP): a retrospective analysis using Korean health insurance claim data 2020–2024 by Soo-Dam Kim, Man Young Park, Eunbyul Cho, Jiyun Cha, Changsop Yang, Sungha Kim

“…This study aimed to evaluate the real-world utilization, clinical effectiveness, and safety of herbal medicine (HM) for FP within this national reimbursement program. …”
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Transforming Non-Digital, Clinical Workflows to Detect and Track Vision-Threatening Diabetic Retinopathy via a Digital Platform Integrating Artificial Intelligence: Implementation... by Peranut Chotcomwongse, Paisan Ruamviboonsuk, Chaiwat Karavapitayakul, Koblarp Thongthong, Anyarak Amornpetchsathaporn, Methaphon Chainakul, Malee Triprachanath, Eckachai Lerdpanyawattananukul, Niracha Arjkongharn, Varis Ruamviboonsuk, Nattaporn Vongsa, Pawin Pakaymaskul, Turean Waiwaree, Hathaiphan Ruampunpong, Richa Tiwari, Viroj Tangcharoensathien

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Development of sequential winning-percentage prediction model for badminton competitions: applying the expert system sequential probability ratio test by Eunhye Jo

“…Future research should focus on developing a program to identify the most effective model among the six and implement it practically.…”
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L’inversion des rôles ? Aménageurs, promoteurs immobiliers et pouvoirs publics dans la régulation des ZAC du Grand Lyon by Romain Maurice

“…The ZAC is a legal framework that allows the public sector to delimit an area for future development and to negotiate the program with the potential developers (either public or private). …”
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On Signifiable Computability: Part II: An Axiomatization of Signifiable Computation and Debugger Theorems by Vladimir A. Kulyukin

“…The first theorem shows that, for a singifiably partially computable function signified by a program on a finite-memory device <inline-formula><math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"><semantics><mi mathvariant="script">D</mi></semantics></math></inline-formula>, the memory capacity of <inline-formula><math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"><semantics><mi mathvariant="script">D</mi></semantics></math></inline-formula> is exceeded when running the program on signifiable discretely finite real numbers outside of the function’s domain. …”
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The genomic copy number determination of improved Cre in transgenic mice using standards derived from megaprimer PCR constructed tandem repeats by Ge Diao, Min Tian, Runbo Li, Jie Huang, Jian Han, Jianxin Guo

“…The established method is a universal and sensitive program for genomic copy number determination of iCre in transgenic mice.…”
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Diagnostics of heat exchange equipment on basis of operating parameters of diesel fuel hydrotreating unit by A. М. Demin, A. P. Naumenko

“…According to the results of calculations on a mathematical model of a typical hydrotreating unit using a real-time diagnostic program based on monitoring operational parameters, the criterion for assessing the state of the reactor unit heat exchanger increases from 1 to 1.37 with an increase in the annulus pollution coefficient. …”
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Individualized effort dynamics and monitoring-based training in sprint kayaking: a practical model for enhancing athlete performance by Aurel Alecu, Valentina Stefanica, Raul Ioan Muntean, Paul Florinel Visan, Ana Maria Tataru, Diana Hristache, Florin Cojanu

“…Results indicate consistent physiological adaptations and enhanced race-specific performance following individualized load modulation based on real-time feedback. EDCM appears feasible for high-performance settings, supporting the value of threshold-based, individualized programming, while warranting replication in broader, controlled studies.…”
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A Novel Solution Technique for the Expansion Planning of Modern Distribution Systems: A Feasibility-Driven Approach by Jonathan A. Marcelo, Gregorio Munoz-Delgado, Javier Contreras, Jose R. Sanches Mantovani

“…Scalability is further evaluated using a real 135-node distribution system.…”
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Enhancing Computational Thinking of Deaf Students Using STEAM Approach by Saowaluck Kaewkamnerd, Alisa Suwannarat

“…The learning program composes four courses: learning concepts, implementing concepts, finding solutions to real problems and developing innovations. …”
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PROJECT METHOD IN STEM EDUCATION USING ARDUINO SOFTWARE AND HARDWARE PLATFORM by Олексій Воронкін, Сергій Лущин

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Inhibition of microRNA-21 via locked nucleic acid-anti-miR suppressed metastatic features of colorectal cancer cells through modulation of programmed cell death 4 by Reza Nedaeinia, Mohammadreza Sharifi, Amir Avan, Mohammad Kazemi, Abdolreza Nabinejad, Gordon A Ferns, Majid Ghayour-Mobarhan, Rasoul Salehi

“…MicroRNAs are endogenous non-coding small RNA molecules that function as post-transcriptional regulators of gene expression. Recently, programmed cell death 4 has been identified as a protein that increases during apoptosis. …”
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Outcomes for Dostarlimab and Real-World Treatments in Post-platinum Patients With Advanced/Recurrent Endometrial Cancer: The GARNET Trial Versus a US Electronic Health Record-Based... by Scott Goulden, Qin Shen, Robert L. Coleman, Cara Mathews, Matthias Hunger, Ankit Pahwa, Rene Schade

“… # Objectives The objective of this study was to compare overall survival (OS) and describe time to treatment discontinuation (TTD) for dostarlimab (GARNET Cohort A1 safety population) with an equivalent real-world external control arm receiving non-anti-programmed death (PD)-1/PD-ligand (L)1/2 treatments (constructed using data from a nationwide electronic health record–derived de-identified database and applied GARNET eligibility criteria)…”
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