CTLA-4 and PD-1 combined blockade therapy for malignant melanoma brain metastases: mechanisms, challenges, and prospects by Jia-Wen Wang, Ying-Fa Feng, Jia-Hui Liu

“…Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1), as critical immune checkpoints, play pivotal roles in the progression of MBM. …”
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Energy Production from Landfill Gas: Short-Term Management by Nuno Soares Domingues

“…The present study introduces the formalism for a computer application that simulates the technical–economic behaviour of the short-term management of biogas for the conversion of electricity, and the mathematical model is formulated as a mathematical programming problem with constraints. A simulation for a case study of short-term management is given using the real landfill data available. …”
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Problems of digital transformation of film distribution by A. R. Akopyan, A. M. Arakelyan, Y. V. Vorontsova, V. V. Krysov

“…The paper reveals that the Governments of many countries have a national policy that is aimed at maintaining internal programming on traditional video platforms. Such policies range from licensing, which requires serving the “public interest” and defines rules for the distribution of certain types of content produced domestically, to requiring content distributors to contribute to the financing of the production of domestic content. …”
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Anti-drug vaccines as a harm reduction strategy: potential, limitations, and translational challenges by Laxit K. Bhatt

“…While traditional harm reduction strategies—such as opioid substitution therapy, needle exchange programs, and contingency management—have improved health outcomes, additional biomedical tools are needed. …”
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Artificial Intelligence (AI) and the University. How AI Will Change Our Approach to Education by Jacek Grzybowski

“…The current expansion of AI is leading to situations where we will not be able to verify whether a given work of literature or a piece of art are the result of human effort (i.e. whether they have come into being as a result of human creativity) or whether they have been generated by computer programming algorithms. We are already aware of the impact that artificial intelligence is having on our everyday lives, so we cannot disregard its influence on educational tasks appertaining to schools and universities. …”
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AMEND 2.0: module identification and multi-omic data integration with multiplex-heterogeneous graphs by Samuel S. Boyd, Chad Slawson, Jeffrey A. Thompson

“…Software is freely available in the R programming language at https://github.com/samboyd0/AMEND .…”
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Improvement of a Subpixel Convolutional Neural Network for a Super-Resolution Image by Muhammed Fatih Ağalday, Ahmet Çinar

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Implementing electronic data collection platform for household surveys in resource-constrained settings by Prasanna Samuel Premkumar, Santhosh Kumar Ganesan, Balaji Pandiyan, Dhivya Kumari Krishnamoorthy

“…The household survey questionnaires were programmed using the Microsoft Excel for data collection in the ODK collect android application. …”
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Monitoring and Controlling in the Process of Managerial Transformation of Enterprises by Poliakova Yevheniia S.

“…The article provides recommendations for overcoming implementation barriers, such as investments in training and workforce development programs, which are crucial for employees to acquire the necessary skills for the effective use of advanced technological tools. …”
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Multi-Depot Pickup and Delivery Problem with Resource Sharing by Yong Wang, Lingyu Ran, Xiangyang Guan, Yajie Zou

“…First, a bi-objective mathematical programming model that minimizes the logistics cost and the number of vehicles is constructed, in which vehicles are allowed to be used multiple times by one or multiple logistics facilities. …”
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Development of a remote therapeutic monitoring platform: applications for movement disorders by Sreetharan Thankathuraipandian, Walter Greenleaf, Anahita Kyani, Tucker Tomlinson, Binesh Balasingh, Erika Ross, Yagna Pathak

“…Wearable technology and mobile health platforms can offer remote monitoring capabilities, allowing for real-time virtual programming with optimization of patients’ therapy, use of digital biomarkers that can help identify the onset, symptoms, medication-related fluctuations and side-effects, and response to DBS treatment. …”
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Retinal “sweet spot” for myopia treatment by Barbara Swiatczak, Hendrik P. N. Scholl, Frank Schaeffel

“…The eye tracker software accessed each individual movie frame in real-time and covered the points of fixation in the movie with a uniform grey patch. …”
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Financial Institutions and poverty Alleviation: A case study of Peoples Bank of Zanzbar (Pbz) in Western District of Zanzibar. by Mohamed, Dadi

“…Findings revealed that the respondents who participated in training and support programs had benefited them. The majority of the respondents felt that they had attained a real change in their lives as compared to themselves before they joined the bank and accessing training services. …”
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Bridging the gap: enhancing data science and leadership knowledge and skills in the context of the public health workforce by Diana Hamer, Madelyn Gustafson, Christine Ortiz Gumina, Danielle C. Landis, Patricia Bockelman, Elaina Perry, Sarah D. Matthews

“…Significant gaps in workforce capacity, accessibility, and training were highlighted, particularly in aligning academic curricula with real-world public health needs.AnalysisThe study revealed a disconnect between current public health programs and workforce preparedness, performance, and practice. …”
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Performance Evaluation of Battery Swapping Stations for EVs: A Multi-Method Simulation Approach by Maria Grazia Marchesano, Valentina Popolo, Anastasiia Rozhok, Gianluca Cavalaglio

“…A hybrid modelling approach combines agent-based discrete event simulation and linear programming to model the dynamic behaviour of batteries and operational processes within the BSS. …”
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Optimal scheduling of district heat pumps conceived for implementation in Energy Management Systems to participate in demand response by Roberto Rocca, Stefano Leonori, Gregorio Fernández Aznar, Riccardo Toffanin, Luis Luengo-Baranguan

“…Nowadays, the exponential growth of Indirect Demand Response (IDR) and Direct Demand Response (DDR) programs is urging researchers to investigate new strategies to enable the provision of flexibility services from any type of energy device. …”
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RISK MANAGEMENT ALGORITHM FOR ENSURING THE SANITARY SAFETY OF THE POPULATION IN THE AREA OF THE OIL REFINERY by M. A. Fomenko, G. A. Fomenko, E. A. Skuratova

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A multi-user multi-operator computing pricing method for Internet of things based on bi-level optimization by Wei Jiang, Huiqiang Wang, Bingyang Li, Haibin Lv, Qingchuan Meng

“…The Internet of mobile things is a promising paradigm that generates, stores, and processes amount of real-time data to render rich services for mobile users. …”
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Tanzanian women´s knowledge about Cervical Cancer and HPV and their prevalence of positive VIA cervical screening results. Data from a Prevention and Awareness Campaign in Northern... by Antje Henke, Ulrike Kluge, Theda Borde, Bariki Mchome, Furaha Serventi, Oliver Henke

“…Limited cancer care facilities, prevention programs and sparse knowledge among community members and healthcare workers contribute to late-stage presentation leading to a high mortality rate. …”
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Gaze behavior and decision-making among handball referees: exploring gender and expertise differences by Jacek Świdwa, Stefanie Klatt, Adam Kantanista

“…The absence of gender differences in gaze patterns challenges prior research suggesting systematic visual search disparities. Future studies in real-game settings are needed to explore the impact of physical and psychological demands on referees’ performance, providing practical insights for training programs.…”
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