The association of miR-126-3p, miR-126-5p and miR-664-3p expression profiles with outcomes of patients with metastatic colorectal cancer treated with bevacizumab by Ondrej Fiala, Pavel Pitule, Petr Hosek, Vaclav Liska, Ondrej Sorejs, Jan Bruha, Ondrej Vycital, Tomas Buchler, Alexandr Poprach, Ondrej Topolcan, Jindrich Finek

“…MicroRNAs regulate the expression of genes involved in several important cancer-related processes including cell adhesion, proliferation, and tumour angiogenesis. …”
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Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial). by Stefan Halbherr, Stefanie Lerch, Sebastian Bellwald, Petra Polakova, Bettina Bannert, Marie Roumet, Roch-Philippe Charles, Martin A Walter, Corrado Bernasconi, Valérie Lisa Halbherr, Camille Peitsch, Pascal C Baumgartner, Céline Kaufmann, Vanessa Aires, Heinrich P Mattle, Alain Kaelin-Lang, Andreas Hartmann, Michael Schuepbach

“…A disease-modifying treatment that could ideally stop the neurodegenerative process is direly needed. Monosialotetrahexosylganglioside (GM1) is a promising molecule with neuroprotective effects in preclinical models of PD and has yielded encouraging results in patients with PD in a randomized placebo-controlled trial. …”
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Health risk assessment of heavy metals based on source analysis and Monte Carlo in the Lijiang River Basin, China by Wanjun Zhang, Cunlin Xin, Wenyue Du, Shi Yu

“…Source analysis using the Positive Matrix Factorization (PMF) model indicated dual contamination drivers from natural geological processes and anthropogenic activities, with industrial and agricultural inputs being the most significant contributors. …”
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Wildlife law and policy by S. Bertouille

“…The various aspects of the processes described above were highlighted in the plenary talk and the five oral communications presented during the session on wildlife law and policy. …”
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Effectively removing antimony Sb(V) and Sb(III) from aqueous solutions by granular ferric hydroxide compared with manganese zeolite and activated carbon by Shyh-Fang Kang, Po-Ching Lee, Jr-Lin Lin, Chia-Hsin Hsu, Yaw-Huei Hwang, Huan-Ping Chao, Hai Nguyen Tran

“…Its maximum adsorption capacity (based on the Langmuir model; Qmax) for Sb(OH)3 ions and Sb(OH)6– anions reached 31,375 and 26,279 μg/g. …”
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Tracking freshwater depletion in Northern Australia: A multi-satellite approach by Christopher E. Ndehedehe, Ikechukwu Kalu, Vagner G. Ferreira, Alex O. Onojeghuo, Oluwafemi E. Adeyeri, Mohammad J. Tourian, Matthew Currell, Sue Jackson

“…Building on these findings, we highlight the unique capabilities and benefits of combining satellite gravity and optical data to enhance our understanding of hydrological processes, while also advancing water governance and management responses to droughts and pressures from water extraction.…”
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Statistics on Differences in the Institutional Composition of the National Economy and Issues Related to its Harmonization by O. V. Morozov, A. G. Biryukov, M. A. Vasiliev

“…Criteria of minimum required and maximum possible scale of the public sector have been defined and it is shown that as of 2016 the integral indicator of the scale of the public sector of the Russian economy does not reach the minimum required value. A quantitative model for optimizing the sectoral composition of the national economy has been constructed. …”
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The WHEAT pilot trial—WithHolding Enteral feeds Around packed red cell Transfusion to prevent necrotising enterocolitis in preterm neonates: a multicentre, electronic patient recor... by Neena Modi, Jon Dorling, Chris Gale, Tjeerd Van Staa, Louise Linsell, Ursula Bowler, Ed Juszczak, Mark A Turner, Sena Jawad, Amanda Forster, Andy King, Jenny McLeish, Helen Robberts, Kayleigh Stanbury

“…The use of a simplified opt-out consent model and embedding trial processes within existing electronic patient record (EPR) systems provide opportunities to increase trial efficiency and recruitment.Methods and analysis We will undertake a randomised, controlled, multicentre, unblinded, pilot trial comparing two care pathways: continuing milk feeds (before, during and after red cell transfusions) and withholding milk feeds (for 4 hours before, during and for 4 hours after red cell transfusions), with infants randomly assigned with equal probability. …”
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Global Methane Budget 2000–2020 by M. Saunois, A. Martinez, B. Poulter, Z. Zhang, Z. Zhang, P. A. Raymond, P. Regnier, J. G. Canadell, R. B. Jackson, P. K. Patra, P. K. Patra, P. Bousquet, P. Ciais, E. J. Dlugokencky, X. Lan, X. Lan, G. H. Allen, D. Bastviken, D. J. Beerling, D. A. Belikov, D. R. Blake, S. Castaldi, M. Crippa, B. R. Deemer, F. Dennison, G. Etiope, G. Etiope, N. Gedney, L. Höglund-Isaksson, M. A. Holgerson, P. O. Hopcroft, G. Hugelius, A. Ito, A. K. Jain, R. Janardanan, M. S. Johnson, T. Kleinen, P. B. Krummel, R. Lauerwald, T. Li, X. Liu, K. C. McDonald, J. R. Melton, J. Mühle, J. Müller, F. Murguia-Flores, Y. Niwa, Y. Niwa, S. Noce, S. Pan, R. J. Parker, C. Peng, C. Peng, M. Ramonet, W. J. Riley, G. Rocher-Ros, J. A. Rosentreter, M. Sasakawa, A. Segers, S. J. Smith, S. J. Smith, E. H. Stanley, J. Thanwerdas, J. Thanwerdas, H. Tian, A. Tsuruta, F. N. Tubiello, T. S. Weber, G. R. van der Werf, D. E. J. Worthy, Y. Xi, Y. Yoshida, W. Zhang, W. Zhang, B. Zheng, B. Zheng, Q. Zhu, Q. Zhu, Q. Zhuang

“…Following Saunois et al. (2016, 2020), we present here the third version of the living review paper dedicated to the decadal CH<span class="inline-formula">₄</span> budget, integrating results of top-down CH<span class="inline-formula">₄</span> emission estimates (based on in situ and Greenhouse Gases Observing SATellite (GOSAT) atmospheric observations and an ensemble of atmospheric inverse-model results) and bottom-up estimates (based on process-based models for estimating land surface emissions and atmospheric chemistry, inventories of anthropogenic emissions, and data-driven extrapolations). …”
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Development and Study of Demodulators for Frequency Hopping Spread Spectrum Signals by D. I. Kaplun, V. V. Gulvanskiy, I. I. Kanatov, D. M. Klionskiy, A. B. Khachaturyan, D. N. Butusov, V. F. Lapizkiy, V. I. Bobrovskiy

“…Demodulation task is encountered in many practical applications including digital signal processing and digital communications. Demodulation is connected with the communication system performance. …”
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Structural and Functional Reorganization of the Sensorimotor Cortex During Ligation of the Common Carotid Arteries (Experimental Study) by L. M. Makarieva, V. A. Akulinin, M. S. Korzhuk, S. S. Stepanov, A. Y. Shoronova, D. B. Avdeev, I. G. Tsuskman

“…Incomplete cerebral ischemia was simulated by irreversible bilateral CCAL (2-vessel model of global ischemia without hypotension) on white rats (n=36). …”
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Release Behavior and Bioaccumulation Characteristics of Organophosphate Esters from Plastics in Marine Aquaculture by Zhi YANG, Dongni LIU, Shengnan HUANG, Xuetian DAI, Wei QIAN, Xiaoshan ZHU

“…This physical integration increases their susceptibility to release into the surrounding environment through various processes, such as volatilization, leaching, abrasion, and dissolution, during the product's lifecycle. …”
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Golden hour management in the patient with intraparenchymal cerebral hemorrhage: an Italian intersociety document by Gianluigi Morello, Daniela Alampi, Raffaele Aspide, Alessandra Beretta, Rita Bertuetti, Federico Bilotta, Etrusca Brogi, Giovanni Buscema, Anselmo Caricato, Davide Caruzzo, Carlo Alberto Castioni, Arturo Chieregato, Andrea Cortegiani, Alessandro De Cassai, Andrea Fabbri, Domenico Gelormini, Paolo Gritti, Lucrezia Guadrini, Alberto Librizzi, Nicola Latronico, Nicola Limbucci, Marina Munari, Edoardo Picetti, Giuseppina Pipitone, Gianluca Pucciarelli, Chiara Robba, Danilo Toni, Salvatore Sardo, Simone Maria Zerbi, Nicola Zugni, Frank Rasulo

“…The main causes include vascular malformations, small- and large-vessel angiopathies, and coagulation disorders. Mortality rates reach approximately 40% at 1 month and 54% at 1 year, largely influenced by early management decisions. …”
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Preparation of Magnetic Photocatalyst Fe₃O₄@SiO₂@Fe-TiO₂ and Photocatalytic Degradation Performance of Methyl Orange in Na₂SO... by Li Sun, Zilong Li, Zhigang Yuan, Ying Liu, Shunqi Mei, Fanhe Meng, Xingyu Ouyang, Yi Xiong, Ke Zhang, Zhen Chen

“…Kinetic analysis of the photocatalytic data, based on a first-order model, was conducted to explore the underlying degradation principles.…”
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Evaluation of the relationship between nutrition and the risk of fatal outcomes from cardiovascular diseases in people with type 2 diabetes by A. K. Kuntsevich, A. O. Shchetinina, S. V. Mustafina, E. G. Verevkin, G. I. Simonova, L. V. Shcherbakova, O. D. Rymar

“…The followup period for the observed cohort, including individuals with T2DM, lasted from 2003–2005 to December 31, 2018 and reached on average 12.8 years (1.1 ± 16.0 years). …”
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The impact of technological mega trends on the development of universities in Iran; A case study of the effects of technological developments on the financing of public universitie... by Reza Naghizadeh

“…These technological developments create opportunities and challenges for universities, which must be responded to in a scientific and policy-making process. In this research, two key research questions have been answered: Question 1: What are the mega trends affecting the future of universities in Iran related to the development of new technologies in the field of education? …”
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Results of a feasibility study of the FReSH START intervention to improve quality of life and other outcomes in people who repeatedly self-harm (Function REplacement in repeated Se... by Bethan Copsey, Alexandra Wright-Hughes, Amanda Farrin, Cara Gates, Kate Farley, Cathy Brennan, Dean McMillan, Christopher D. Graham, Chris Bojke, Richard Mattock, Adam Martin, Petra Bijsterveld, Judith Horrocks, Suzanne Hartley, Marsha McAdam, Dafydd Hammond-Jones, Louise D. Bryant, Allan House, Elspeth Guthrie, the FReSH START lived experience group

“…A parallel qualitative study interviewed a sample of therapists and participants to refine the intervention and logic model ahead of a definitive RCT. Results We reached our target of 30 recruited participants and 15 therapists delivered the intervention in a way that was acceptable to participants. …”
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Analysis of Factors Influencing the Development of Community-Based Tourism in Rural Areas, Case Study: Villages Targeted by Tourism in the Markazi Province by Hamid Afshari, Behrouz Mohammadi Yeganeh, Hossein Farahani, Mehdi Cheraghi

“…The information has been processed and coded based on line-by-line analysis technique in MAXQDAversion 20 software. …”
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Sociological Explanation of the Impact of Power Structure in Family on Social Cynicism with Emphasis on the Moderating Role of Social Class (Case Study: Citizens Aged 18 years and... by Zahra Tork Ladani, Hamid Dehghani, Vahid Ghasemi

“…This study aimed to theoretically and empirically develop an analytical model that examined the influence of family power structures (independent variable) on social cynicism (dependent variable), with social class serving as a moderating variable. …”
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Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…On the other hand, innovation ecosystems have gained increasing importance in the last decade, and so far, numerous studies and models of innovation ecosystems have been presented in different industries and sectors. …”
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