The Effects of Hot Spring Aquatic Exercise for 4 Weeks on Lower Extremity Strength and Balance Ability in Individuals With Nonspecific Knee Pain by Ki-Song Kim, Tae-Hyeong Kim, Jong-Min Woo, Sunhee Lee, Hana Yu, In-Cheol Jeon

“…The hot spring aquatic exercise consisted of aquatic walking, aquatic stretching, aquatic side step, aquatic forward reach, aquatic squat, leg lift, and aquatic arm and leg rotation. …”

Formulation Optimization and Quality Analysis of Dendrobium officinale Chewable Tablets by Wenyu ZHANG, Xianshu FU, Xue BAI, Shiwen WU, Jiabin LI, Xiaoping YU, Mingzhou ZHANG, Zihong YE

“…To explore whether Dendrobium officinale, Polygonatum sibiricum, and Ziziphus jujuba can be used as active pharmaceutical ingredient (APIs), a functional snack that is easy to carry and eat was developed. …”
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Biodegradable Liquid Slow-Release Mulch Film Based on Bamboo Residue for Selenium-Enriched Crop Cultivation by Chaoqi Chen, Zhaoshuang Li, Kuaile Yin, Lei Li, Zhen Zhang, Xu Xu, He Liu, Yan Qing, Xingong Li, Yiqiang Wu

“…The weed suppression mechanism of PVA@CMC/QL was explained through the lens of density functional theory. In addition, the selenium content of pak choi seedlings under PVA@CMC/QL cover could reach 28.5 μg/kg, making the mulch film both degradable and highly reusable. …”
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Equine Adipose-Derived Mesenchymal Stromal Cells Release Extracellular Vesicles Enclosing Different Subsets of Small RNAs by Stefano Capomaccio, Katia Cappelli, Cinzia Bazzucchi, Mauro Coletti, Rodolfo Gialletti, Franco Moriconi, Fabrizio Passamonti, Marco Pepe, Stefano Petrini, Samanta Mecocci, Maurizio Silvestrelli, Luisa Pascucci

“…Enrichment analyses were performed to infer involved pathways and functional categories. Results. Electron microscopy showed the presence of vesicles ranging in size from 30 to 300 nm and expressing typical markers. …”
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Prevalence and screening of hemoglobinopathies and glucose-6-phosphate dehydrogenase deficiency in Yemeni blood donors by Mohammed A.W. Almorish, Ahmed M. E. Elkhalifa, Elsharif. A. Bazie, Elsadig Mohamed Ahmed, Isameldin Mohamed Abdalla Hamad, Omer M. Aburaida, Rabei M. Elbadry, Yasir S. Kaloda, Tarig Babikir Algak Khalid

“…Various tests were performed, including complete blood count (CBC), serum ferritin, sickling test, G6PD assay, NESTROF test and high-performance liquid chromatography (HPLC).Results The prevalence of hematological abnormalities among blood donors reached 68.9%, with functional RBC abnormalities at 51.9%, leukopenia at 10.4%, thrombocytosis at 1.9%, and thrombocytopenia at 4.7%. …”
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Effects of curing age and magnesium slag grinding time on mechanical properties and hydration characteristics of magnesium slag-based backfill materials by Xiaobing Yang, Jian Yang, Xi Wang, Shenghua Yin, Zepeng Yan, Xizhi Zhang, Gongcheng Li, Xun Chen, Yaobin Qi, Wei Chen

“…Linear and quadratic polynomial functions effectively illustrate the relationship between both curing age as well as grinding time with respect to compressive strength in MS-based backfill. …”
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Patient-reported improvements in paroxysmal nocturnal hemoglobinuria treated with iptacopan from 2 phase 3 studies by Antonio M. Risitano, Carlos de Castro, Bing Han, Austin Kulasekararaj, Jaroslaw P. Maciejewski, Phillip Scheinberg, Yasutaka Ueda, Susan Vallow, Georgina Bermann, Marion Dahlke, Rakesh Kumar, Régis Peffault de Latour

“…In APPLY-PNH (iptacopan, n = 62; C5i, n = 33), more patients in the iptacopan versus the C5i group reached the MWPC threshold for FACIT-Fatigue (51% vs 11%). …”
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Factors driving the variation in soil fertility associated with extension of the alfalfa (Medicago sativa L.) cultivation period by Zeyu Liu, Junqi Wang, Xinhe Shan, Pinhang Liang, Lizhao Fan, Chengyu Song, Zhaopu Jia, Yuxia Zhang, Yunlong Zhang, Lei Liu, Ding Huang

“…These findings underscore the effects of continuous alfalfa cultivation on soil physicochemical, microbial properties and functional contributions to soil health in Henan Province. …”
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Coupling genome-wide continuous perturbation with biosensor screening reveals the potential targets in yeast isopentanol synthesis network by Qi Xiao, Jingjing Shi, Lixian Wang, Guoping Zhao, Yanfei Zhang

“…While enhanced production of isopentanol has been achieved in a variety of chassis, the fermentation yield has not yet reached levels suitable for industrial-scale production. …”
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An organotypic human melanoma-in-skin model as an in vitro tool for testing Vγ9Vδ2-T cell-based immunotherapy by E. Michielon, L.A. King, T. Waaijman, M. Veth, S.W. Spiekstra, H.J. van der Vliet, S. Gibbs, T.D. de Gruijl

“…Evidence of actual tumor cell elimination, although not significant, was only obtained after preincubation of Mel-RhS with pamidronate, a phosphoantigen-inducing agent, indicating the need for additional T cell receptor-mediated signaling for Vγ9Vδ2-T cells to reach their full oncolytic potential. Conclusions: This study highlights the viability and persistence of Vγ9Vδ2-T cells within the 3D microenvironment, their migratory and antitumor functionality, and the suitability of the model for testing T cell-based therapies, contributing both to the understanding of Vγ9Vδ2-T cell biology and their application in cancer immunotherapy.…”
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Phytochemical Profiling of Processed Açaí Pulp (<i>Euterpe oleracea</i>) Through Mass Spectrometry and Its Protective Effects Against Oxidative Stress in Cardiomyocytes and Rats by Jefferson Romáryo Duarte da Luz, Eder Alves Barbosa, Rubiamara Mauricio de Sousa, Maria Lúcia de Azevedo Oliveira, Marcela Fabiani Silva Dias, Ingrid Reale Alves, Gisele Custódio de Souza, Elenilze Figueiredo Batista Ferreira, Carla Guzmán-Pincheira, Maria das Graças Almeida, Gabriel Araujo-Silva

“…Hydroxyl and superoxide radical scavenging activities reached 80% inhibition, similar to that of ascorbic acid. …”
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The Effectiveness and Feasibility of Palliative Care via Video Telemedicine for Patients with Advanced Cancer: A Nonrandomized Prospective Clinical Trial Comparing Combination of T... by Akihiko Chida, Yasuo Hamamoto, Kenro Hirata, Yasunori Sato, Eiichiro So, Shotaro Kishimoto, Satoko Noguchi, Sara Horie, Yuki Saito, Keitaro Shimozaki, Kai Tsugaru, Kazuhiro Togasaki, Kenta Kawasaki, Hideyuki Hayashi, Takanori Kanai

“…The primary endpoint was QOL, which was evaluated using the difference in the Functional Assessment of Cancer Therapy-General (FACT-G) scores between baseline and one-month follow-up. …”
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Implementation and effectiveness of a nurse-enabled, shared-care follow-up model for early breast cancer survivors (The IBIS-Survivorship Study): protocol for a stepped-wedge clust... by Karla Hemming, Jane Turner, Meinir Krishnasamy, Nicolas H Hart, Patsy Yates, Helen Skerman, Elizabeth Eakin, Jon Emery, Jane Mahony, Kerry Patford, Bogda Koczwara, Fiona Crawford-Williams, Caroline Kristunas, Raymond J Chan, G Bruce Mann, Mary Azer, Louisa G Collins, Jasotha Sanmugarajah, Bethany Crowe, Gillian Blanchard, Laura Healey, Rhea Liang, Paul Craft, Amy Shorthouse, Ruth McCaffery

“…Health-related quality of life at 12 months assessed by the Functional Assessment of Cancer Therapy - Breast Cancer questionnaire will be the primary endpoint, along with a range of patient-reported outcomes, safety indicators and cost-effectiveness measures as secondary endpoints. …”
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Climate, soil and management factors drive the quantitative relationships between soil fertility and spring maize water productivity in northern China by Jiao Shi, Minggang Xu, Xinhua He, Huaiping Zhou, Jianhua Li

“…The potential QRs determined by boundary functions were reached up to 6.2, 5.26 and 6.12 kg m−3 in NW, at dry years and under NPK, respectively. …”
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Arginine-Mediated Liver Immune Regulation and Antioxidant Defense in Largemouth Bass (<i>Micropterus salmoides</i>): Multi-Omics Insights into Metabolic Remodeling During <i>Nocard... by Yu-Long Sun, Shuai-Liang Zhang, Feng-Feng Zhou, Yuan-Xin Qian, Yang He, Run-Zhe Zhang, Fen Dong, Qiang Chen, Han-Ying Xu, Ji-Teng Wang, Yu-Ting Deng, Tao Han

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Prognostic value of HLA class I expression in patients with cutaneous melanoma and soft tissue sarcomas treated with cancer-testis antigens-based vaccine by Tatiana L. Nekhaeva, Aleksei V. Novik, Dmitry V. Girdyuk, Anna B. Danilova, Polina A. Savchenko, Alina V. Grigoryevskaya, Maria A. Nekrasova, Natalia A. Efremova, Andrey V. Orekhov, Irina A. Baldueva

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INTERRELATION OF TEMPOROMANDIBULAR JOINT DYSFUNCTION IN PATIENTS WITH GYNECOLOGICAL CHANGES IN ANAMNESIS ACCORDING TO THE QUESTIONNAIRE SURVEY by V.M. Novykov, A.I. Shvets, K.Y. Rezvina, M.A. Korostashova

“…Much attention is drawn to the study of estrogen, which, in addition to regulating the functioning of the reproductive system in a woman's body, also performs a number of other important functions, including helping the joint to remain healthy - preventing calcium leaching, stimulating collagen recovery and the work of osteoblasts. …”
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Efficacy and safety of rapid dose escalation of methotrexate in rheumatoid arthritis. Results of the multicenter “METEOR” study by V. N. Amirjanova, E. Yu. Polishchuk, O. N. Anoshenkova, I. B. Vinogradova, E. V. Zonova, L. V. Ivanova, R. R. Samigullina, T. S. Salnikova, E. L. Shakhramanova, E. I. Shmidt, S. P. Yakupova, A. M. Lila, E. L. Nasonov

“…The evaluation of the effectiveness of therapy, functional status, and QoL was carried out after 4–12–18–24 weeks.Results. …”
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Tratamiento quirúrgico de fractura subcapital de cadera no desplazada: Femoral Neck System vs. tornillos canulados. Estudio comparativo by P. Lalueza-Andreu, Á. Martínez-García, P. Checa-Betegón, J. García-Coiradas, J.A. Valle-Cruz, F. Marco-Martínez

“…The FNS also presented a lower rate of avascular necrosis (0% versus 11.1%, p = 0.391) and nonunion (0% versus 20%, p = 0.163), although these differences did not reach statistical significance. Conclusions: Although both treatment methods, cannulated screws and the FNS, showed similar short-term functional outcomes in the management of undisplaced subcapital femoral fractures, the FNS demonstrated a significantly lower rate of complications and reoperations. …”
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[Translated article] Surgical treatment of non-displaced subcapital hip fracture: Femoral Neck System vs. cannulated screws. Comparative study by P. Lalueza-Andreu, Á. Martínez-García, P. Checa-Betegón, J. García-Coiradas, J.A. Valle-Cruz, F. Marco-Martínez

“…The FNS also presented a lower rate of avascular necrosis (0% versus 11.1%, p = 0.391) and nonunion (0% versus 20%, p = 0.163), although these differences did not reach statistical significance. Conclusions: Although both treatment methods, cannulated screws and the FNS, showed similar short-term functional outcomes in the management of undisplaced subcapital femoral fractures, the FNS demonstrated a significantly lower rate of complications and reoperations. …”
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